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Deleted member 23558
God make my neurotransmitters great inc
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Might be of interest to looksmaxers in the 25-30 range since tretinoin may have helped you with collagen but your elasitn levels may be decreasing especially if you tan hard:
The expression of IGF-1 decreases with increasing age40. In this 3D skin model, we have shown an upregulation of IGF-1 transcription upon MB treatment (Fig. 6D), which further supports the idea that MB treatment increases collagen in the dermis. Elastin, the second most abundant ECM component, is a fibrous protein that contributes to 2~4% of the dry weight of the dermis. It provides natural elasticity and strength to human skin and also plays a role in tissue repair3, 41. We found a robust increase in elastin expression by MB, suggesting that MB treatment enhances skin elasticity and improves skin wound healing (Fig. 6A–C). Based on these results, we speculate that by regulating and orchestrating the expression of these ECM genes, MB may reduce the formation of skin wrinkles. In addition, the enhanced skin hydration from MB application will delay the development of wrinkles.
The expression of IGF-1 decreases with increasing age40. In this 3D skin model, we have shown an upregulation of IGF-1 transcription upon MB treatment (Fig. 6D), which further supports the idea that MB treatment increases collagen in the dermis. Elastin, the second most abundant ECM component, is a fibrous protein that contributes to 2~4% of the dry weight of the dermis. It provides natural elasticity and strength to human skin and also plays a role in tissue repair3, 41. We found a robust increase in elastin expression by MB, suggesting that MB treatment enhances skin elasticity and improves skin wound healing (Fig. 6A–C). Based on these results, we speculate that by regulating and orchestrating the expression of these ECM genes, MB may reduce the formation of skin wrinkles. In addition, the enhanced skin hydration from MB application will delay the development of wrinkles.
