Retin-A Causes Loss of Subcutaneous Fat

DrunkenSailor

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janoycresva said:
Acutally made a thread a year ago about me being like 230lbs yet having almost no fat around my face. I used retin-a for years growing up to keep my acne under control. I think this is legit, I have very bad fat loss.
Can you post the link of the thread itt pls?
 
RAITEIII

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TubOfLard said:
Surely it wouldve been a looksmax if it removed fat from your face, no?
To a certain extent.

Now I truly don't know what to believe :feelswhy: because I'm seeing less undereye support and when I touch my face i feel less subcutaneous fat too, but that's fat that I do not need to lose jfl.

I'll put it on my abs everyday that will tell me the reality.
janoycresva said:
Acutally made a thread a year ago about me being like 230lbs yet having almost no fat around my face. I used retin-a for years growing up to keep my acne under control. I think this is legit, I have very bad fat loss.
How tall?

Maybe if I'm in calorie surplus there are less downsides...?

What was ur face like before and after starting?
 
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DrunkenSailor said:
Can you post the link of the thread itt pls?
can't find the link, sorry buddy boyo. i'm not sure if it was on .co or here.
RAITEIII said:
To a certain extent.

Now I truly don't know what to believe :feelswhy: because I'm seeing less undereye support and when I touch my face i feel less subcutaneous fat too, but that's fat that I do not need to lose jfl.

I'll put it on my abs everyday that will tell me the reality.

How tall?

Maybe if I'm in calorie surplus there are less downsides...?

What was ur face like before and after starting?
6'0, it's hard to remember my face before starting. i do believe I had a very plump child like face tho, good collagen. i really overused it though.
 
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RAITEIII

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I don't want to, but as of today I'm quiting retin a. I can clearly see a loss of undereye fat. Maybe it's not that and just weight related but i don't wanna risk tbh...
 
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rawdogprince said:
i didnt read. You need to post pics of why this is bad. also can't u just junkfood max your fat back?
Yeah, My orbitals lost all of there fat when I was only eating one meal a day and came back once I started eating more.
RAITEIII said:
I don't want to, but as of today I'm quiting retin a. I can clearly see a loss of undereye fat. Maybe it's not that and just weight related but i don't wanna risk tbh...
rather than quit you should try Icing your eye area. I did that with eating more and plumped up fast
 
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DrOtaku said:
Yeah, My orbitals lost all of there fat when I was only eating one meal a day and came back once I started eating more.

rather than quit you should try Icing your eye area. I did that with eating more and plumped up fast
Why do u speculate that icing your eye area has benefits when there are studies indicating that applying cold kills fat cels?
 
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RAITEIII said:
Why do u speculate that icing your eye area has benefits when there are studies indicating that applying cold kills fat cels?
I noticed more fat around the eyes and less around the cheeks personally. Almost as if the fat moves to the organs.
 
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RAITEIII said:
Why do u speculate that icing your eye area has benefits when there are studies indicating that applying cold kills fat cels?
DrOtaku said:
I noticed more fat around the eyes and less around the cheeks personally. Almost as if the fat moves to the organs.
The puffiness under the eye might help by applying ice, it won't do anything for fat cells (as far as I'm aware). You might just have a lot of fluid retention in that area, does not sound like fat.
 
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Haven't been following these threads too much lately, so what is teh general current take on retin A? Is it something you should start with as soon as possible no matter what?
 
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DrOtaku said:
I noticed more fat around the eyes and less around the cheeks personally. Almost as if the fat moves to the organs.
Idk what to believe lol. All your body is composed by organs, I don't see a reason for cels to respond different and have a complete opposite effect...
 
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jackthenerd said:
Haven't been following these threads too much lately, so what is teh general current take on retin A? Is it something you should start with as soon as possible no matter what?
I started Retin-A after I read this thread.
 
RAITEIII

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jackthenerd said:
Haven't been following these threads too much lately, so what is teh general current take on retin A? Is it something you should start with as soon as possible no matter what?
More doubts than ever for me lol.

Just checked back on the mirror and yes I'm quiting till gaining some fat back lol I can't look at those sunken eyes jfl
 
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I'm just coming to report that retin a melted away fat under my eyes. I really wouldn't recommend using it there jfl.

Most people are landwhalemaxxed that's why they never notice jfl
 
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RAITEIII said:
I'm just coming to report that retin a melted away fat under my eyes. I really wouldn't recommend using it there jfl.

Most people are landwhalemaxxed that's why they never notice jfl

By under eyes you mean just above the cheekbone right under the eye or also the upper part of the cheek?
 
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EverythingMattersCel said:
By under eyes you mean just above the cheekbone right under the eye or also the upper part of the cheek?
Sorry i didn't notice the thread. I noticed everything thinner but my undereye is what hurt me lol
 
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Lev Peshkov

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So is this cope or not JFL
 
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Lev Peshkov said:
So is this cope or not JFL
I don't think so. My eye area is over level tbh
 
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RAITEIII said:
I don't think so. My eye area is over level tbh
Rip, would fat grafts save you?
 
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RAITEIII said:
Idk bro. I'm junk maxxing u. U
JFL so it's a prank. Dude my English is so bad
 
RAITEIII

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Lev Peshkov said:
JFL so it's a prank. Dude my English is so bad
What's a prank, sorry? My English also kinda sucks btw
 
Lev Peshkov

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Lol does it affect fat or where u joking?
RAITEIII said:
What's a prank, sorry? My English also kinda sucks btw
 
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Lev Peshkov said:
Lol does it affect fat or where u joking?
Not joking, i personally experienced rapid worsening.
 
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Fuck man that sucks
RAITEIII said:
Not joking, i personally experienced rapid worsening.
 
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RAITEIII said:
Everyday it's even more over than before
Motivation to surgery max tho tbh
 
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RAITEIII said:
Not joking, i personally experienced rapid worsening.
Cope
 
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I am gonna start Retin-A just for this then lmao
 
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where to get retin a?
 
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PapiMew @PapiMew so aslong as i dont use it around the eyes i shoul be good right?
 
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razerftw said:
I am 30 years old, people here rated me around 5.5 PSL. Last girl I banged 2 days ago 17y old:
This is how I look now, have some hairloss (started Minoxidil recently)
Height?
 
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RAITEIII said:
I'm just coming to report that retin a melted away fat under my eyes. I really wouldn't recommend using it there jfl.

Most people are landwhalemaxxed that's why they never notice jfl
Post before and after or shut the fuck up dude.
 
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This was mentioned previously in this thread but let me go into more depth.

Retin-A and other things derived from Vitamin A have been shown to lower white adipose (bad fat!). But this is only prevalent in systematic effects of tretinoin. Although oral intake has both systematic and topical effects (works similarly to accutane or Isotretinoin), tropical tretinoin does not have systemic effects at all and is purely cosmic. Topically, tretinoin causes cells on the skins surface to produce more collagen which allows for the structure of the skin on the face to be more sturdy which is the exact opposite, so topical effects are desirable and are present in both forms. Unfortunately not enough research has been done to completely confirm this. Also think of it like this. Wrinkles are difficult to erase, but fat pads can easily be replaced with fat transfer or fillers. I would rather have perfect skin with shit pads than damaged skin with good fat pads.

TLDR: Loss of subcutaneous fat only applies to oral tretinoin. Topical effects are good and is present in both oral and tropically applied forms. Systematic effects may be harmful but are only exist in oral tretinoin. But even then the fat it burns is bad fat.
 
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JeremyMeeks

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elfmaxx said:
Post before and after or shut the fuck up dude.

Experienced same thing - retin-a doesn't do shit for under eyes + eyelids so don't put it near there at all
 
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Stare said:
Good
I am gonna start using that too, just waiting for the quarantine to end.
Update.
More then 1 month in using that stuff.
It helped lessen dark circles significantly. But it's not a magical difference.
It did :
* Add a bit of volume
* Caused tightening of the skin there
* Colorating of skin changed a bit, maybe due to it promotes skin thickness growth a bit.

All 3 above things caused some change.
I went from visible dark circles. To dark circles visible Lite
 
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eduardkoopman said:
Update.
More then 1 month in using that stuff.
It helped lessen dark circles significantly. But it's not a magical difference.
It did :
* Add a bit of volume
* Caused tightening of the skin there
* Colorating of skin changed a bit, maybe due to it promotes skin thickness growth a bit.

All 3 above things caused some change.
I went from visible dark circles. To dark circles visible Lite
Thank you for reporting back.
So, it works but isn't a holygrail. People shouldn't expect getting Chico's eye area while on it.
 
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I'm still breaking out around the chin from the stuff. Purge has been ongoing for 5 weeks now. I have put 0.025% around the chin, jaw and upper lip, 0.05% everywhere else.
 
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EverythingMattersCel said:
I'm still breaking out around the chin from the stuff. Purge has been ongoing for 5 weeks now. I have put 0.025% around the chin, jaw and upper lip, 0.05% everywhere else.
Keep going.
 
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Stare said:
Thank you for reporting back.
So, it works but isn't a holygrail. People shouldn't expect getting Chico's eye area while on it.
truth.
My imporvement was/is kinda like this picture, actually my improvement is alittle bit better, like maybe 1 teint less dark "circles".
less dark circles (I had limited/no wrinkles already there anyways, so that didn't need fixing). BUT not totally gone, at all either.
Worth the 60 euro's (for ONLY 15 ml)?? depends on your budget/income. But you can improve a little bit

 
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JeremyMeeks

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PapiMew said:
Edit: It seems like a got abundance of questions on why this is bad. First, I recommend you at least try to read most of the thread. If you can't, refer to my [Note:] at the very bottom.

Now why this is bad you ask? It depends on how you look at it but facial fat is key in creating facial fullness alongside collagen. If you want more insight look up the results of subcutaneous fat loss over a span of time.



Also, why this might be good? Let’s say you are predisposed to this side effect. You could indefinitely use it as spot reduction.

TLDR: Transretinoic acid impairs the PPAR-gamma transcription factors that control lipogenesis. The bulk of those who experience this effect are relatively young and thus have not dealt with the UV-induced fat loss common in older people, so that is likely why the fat loss is more pronounced and noticeable.

Background: Saturday night I mentioned to a couple of users about how I when I tried Retin-A for a couple of months earlier in the year I got acne scars for the first time. Another user told me they shared the same experience. However, they also mentioned they heard that Tretinoin may cause fat loss, so they were using it very scarcely if any at all. I indefinitely assumed it was an external factor (Diet, Lifestyle) and Retin-A couldn't have possibly been the root of the problem. This was news to me as I never had heard such a claim.

That led me to decide to Google --> Retin-A Fat Loss and well that led me down a rabbit hole that I will share…

The first thread I opened was this: https://www.realself.com/question/atlanta-la-retin-a-cause-fat-loss-please-answer

Summary: A user on Realself complained about fat loss around the cheeks after only a few weeks of 0.05% usage. OP claimed she hadn’t changed anything relating to diet or lifestyle. The only external factor that had been changed was the addition of tretinoin.

Dr. Morgan replied claiming she does notice a sudden loss of buccal fat, which is unusual. She refers to multiple laboratory studies on mice that show that vitamin A can lead to loss of fat or loss of different kinds of fat. Furthermore, she does claim that there have yet to be any studies conducted that claim Retin-A caused fat loss in humans.

The very next thread pertained more to me. A user claiming they had experienced acne scars.
I then decided to look into some studies, I needed some scientific research backing these anecdotal claims.

Studies claiming that retinoic acid directly impairs the process of adipogenesis by inhibiting adipocyte differentiation in several ways both in Vivo (When research or work is done with or within an entire, living organism) and Vitro (Work that's performed outside of a living organism):

To summarize the studies are claiming retinoids do indeed inhibit fat production in some shape or form.
User on reddit summarized this very well:
https ://www.reddit.com/r/SkincareAddiction/comments/8rn11p/anti_aging_how_to_fix_deplated_looking_face/e18sr1h/

A study claiming that Vitamin A ingested orally can affect fat adiposity in mice:
Vitamin A is a regulator of adipose growth.Tretinoin (Retin-A) is a derivative of Vitamin A. High doses of Vitamin A can cause a significant reduction in adipose index, and a significant reduction in white adipose (Fat).

Why has there been no clinical trials in which participants noted a loss in facial fat?
  • Most literature on retinoids has been performed with middle-aged females as subjects.
  • Perhaps a loss in subcutaneous fat would not be noted in these cases because most of the facial fat of people in this age group has already been nuked by chronic UVA ray exposure.
  • Also, there has been no long-term research following people who have used retinoids for 20+ years.
Note: I genuinely think that there might be some sort of genetic component that puts certain people at more of a risk. I don't think that drastic fat loss will occur in the majority of people who use retinoids, and may very well not apply to your skin type and I think it is also very possible that the effects of retinoids are not as well understood as many would like to believe.

Do you think how much retin-a is applied can affect this.

Personally (I know many other people do this) - I use about 2-3 pea-sized amounts for my face and neck. Do you think just using a pea size amount (maybe a bit less) and not applying it anywhere near to the under-eye area (tear troughs or eye-cheek area) can prevent the loss of volume or at least reduce it.

I have experienced fat loss like you mentioned.
 
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eduardkoopman said:
Update.
More then 1 month in using that stuff.
It helped lessen dark circles significantly. But it's not a magical difference.
It did :
* Add a bit of volume
* Caused tightening of the skin there
* Colorating of skin changed a bit, maybe due to it promotes skin thickness growth a bit.

All 3 above things caused some change.
I went from visible dark circles. To dark circles visible Lite
How long does that flask last? Is there any cheaper alternative?
 
eduardkoopman

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TITUS said:
How long does that flask last? Is there any cheaper alternative?
how long it's gonna last? I guestimate 3 months max.

So I think the main ingredients in that product are DMAE
and Hyalronic acid.

Now hylaroinc acid I could by for cheap I know. https://www.douglas.nl/productbrand_015497.html

But the DMAE. I dunno yet where I could buy that?

if these 2 things/ingredients do the trick. Then one could just buy DMAE and Hyalronic acid, and apply then both to the eye erea. Thyat would be alo cheaper.
but i'm not sure if these 2 main ingredients in that product from Pericore do all the work, or some of the other ones do alot as well.

You could try out.
 
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Applying tretinoin every night thickens collagen and necessitates daily spf50 usage which combats the UV related fat loss which is more powerful than whatever fat loss tretinoin causes (pic unrelated)
 
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lifefuel i have disproportionaly fat cheeks retin a is literally godsent to me
 

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