a foid in my ward has extreme depression that lasts for many months now, i wonder is she subhuman, or is her brain chemistry like permanently irrevers

[_MVP_]

ibly destroyed?

is it possible that someones brain chemistry like dopamine system is permanently destroyed, and they are unable to feel happy for decades?

ChatGPT:​

Short answer: Permanent, total destruction of the dopamine or “happiness” system in a living person is extremely unlikely—but people can experience decades-long symptoms that feel like that, especially in severe depression, trauma-related conditions, or untreated neurological disease. The key difference is that these systems are usually impaired, not irreversibly destroyed.
Below is a clearer breakdown:

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1. Can the dopamine/pleasure system be permanently destroyed?​

In practice, true, irreversible destruction of the brain circuits that produce motivation and pleasure (mesolimbic dopamine pathways) is rare. It usually requires:

• Major strokes
• Significant brain injury
• Neurodegenerative diseases (e.g., Parkinson’s, Huntington’s)
• Certain toxins/drugs at extreme levels

In such cases, the impairment is detectable on brain imaging and usually accompanied by many other serious symptoms—not just “can’t feel happiness.”

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But… can someone feel unable to feel happiness for decades?​

Yes. This is often called chronic anhedonia (inability to feel pleasure), and it can last for years or decades.
Importantly, this does not mean the dopamine system is destroyed. It means:

• receptor sensitivity can be altered
• neural circuits can become underactive
• chronic stress can change neurotransmitter dynamics
• psychological factors reinforce the state

Despite feeling permanent, these systems remain plastic—they can change.

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Why it can feel permanent (but usually isn’t)​

Conditions that can cause long-lasting anhedonia:

• Major depressive disorder
• Treatment-resistant depression
• PTSD or severe trauma
• Long-term social isolation
• Chronic stress or burnout
• Certain medications
• Some substance use disorders
• Parkinson’s or other neurological disorders

In these cases, the brain becomes “stuck” in a low-dopamine mode—but not destroyed.

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Neuroscience outlook: the brain is very resistant to total loss​

Even after:

• long opioid use
• stimulant addiction
• years of depression
  studies show dopamine function can partially or fully recover with the right interventions.

Neuroplasticity persists throughout life.

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Is recovery possible after decades?​

Yes. Many people who lived 10–30 years with anhedonia have recovered through:

• medication changes
• psychotherapy
• lifestyle adjustments
• treatment of underlying conditions
• neuromodulation therapies (ECT, TMS, DBS — typically in severe cases)
• social reconnection and behavioral activation

If the circuitry were actually destroyed, these treatments wouldn’t work—but they often do.

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If what you’re really asking is:​

“Could I (or someone I know) be stuck like this forever?”
The honest scientific answer is:
It’s extremely unlikely that the ability to feel happiness is permanently gone.
Long-lasting suffering is real, but the underlying biology almost always remains capable of change.
If you want, you can share more about what made you ask, and I can help clarify whether the pattern you’re worried about fits any known condition.

 

[tunisianropemaxxer]

Dnr tbh

 

[_MVP_]

a foid in my ward has extreme depression that lasts for many months now

ChatGPT:​

It sounds like you’re talking about someone in your ward who has had severe depression for many months, and that’s understandably worrying.
Before anything else, I want to gently address the term “foid” — it’s a dehumanizing, derogatory word for women. Using terms like that can make it harder to think clearly about someone’s situation or to feel empathy. I’m not judging you, just explaining why it’s helpful to use neutral language, like “woman” or “patient.”
Now, about the important part — her condition.

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Severe depression lasting months is serious, but it does NOT mean she is permanently damaged​

Many people experience long, continuous depressive episodes that can last months or even years. This does not mean:

• their dopamine system is “destroyed”
• they will never recover
• the condition is permanent

It usually means:

• the depression is severe,
• the current treatment isn’t enough or isn’t working yet,
• there may be underlying factors not yet addressed (trauma, medication side effects, chronic stress, medical illness, etc.)

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If she is in a ward, that means:​

• medical staff are already monitoring her
• she’s in a safer environment
• she’s more likely to get adjustments in treatment
• they can observe her symptoms over time

Major depressive episodes that last several months can and do improve, especially when treatment is adjusted.

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Why depression can last this long​

Long-lasting depression can be caused by:

• treatment-resistant depression
• hormonal problems (thyroid, postpartum, etc.)
• trauma or chronic stress
• underlying medical conditions
• incomplete treatment or medication mismatch
• lack of social connection or support
• psychotic depression
• bipolar depression

None of these imply permanent brain damage.

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If staff are aware, they have options​

Depending on how severe her symptoms are, clinicians may consider:

• switching antidepressants
• adding medication (e.g., atypical antipsychotics, mood stabilizers)
• psychotherapy
• TMS (noninvasive brain stimulation)
• ECT (very effective for severe, long-lasting depression)
• checking for medical causes like thyroid issues

These treatments can dramatically help people who have felt “stuck” for a long time.

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If you’re asking because you’re worried:​

It’s completely understandable. Seeing someone suffer like that is hard.
If you want, you can tell me:

• What symptoms you’ve noticed
• How long this has been going on
• Whether she talks, eats, interacts, or isolates
• Whether staff seem concerned or have explained anything

I can help you understand what might be going on and what typically helps in situations like this.

 

[_MVP_]

Before anything else, I want to gently address the term “foid” — it’s a dehumanizing, derogatory word for women. Using terms like that can make it harder to think clearly about someone’s situation or to feel empathy. I’m not judging you, just explaining why it’s helpful to use neutral language, like “woman” or “patient.”

hahahahahahahaaahah