Antagonizing the mineralocorticoid receptor

[Clavicular]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).

I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.

Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.

The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

 

[Clavicular]

@Alexanderr @NorwoodAscender @Rigged any sciencecels ?

 

[Deleted member 4633]

Just use sprio, no price barrier, won't feminize you because you're on gear and it's probably equally as efficacious Eplerenone

 

[fluoride1337]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).
View attachment 3240353
I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.
View attachment 3240359
Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.
View attachment 3240366
The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

Clavicular.

Boy oh boy, where do I even begin. Clavicular... my master slayer, my PSL god. I have admired you ever since I first laid eyes on your posts. The way you talk about 'slaying beckies' with such confidence, your dedication to nuking DHT with dutasteride, and your relentless pursuit of perfection through roiding and other looksmaxxing tactics—it all strikes fear into the heart of mere normies. Your willingness to go to any lengths for that ideal jawline, even if it means battling a bit of bloat—that's true dedication. We all know it's just temporary water retention from your cycle, anyway.

You've had your ups and downs, but you never gave up hope in the looksmaxxing journey. You're even more amazing when you drop knowledge bombs on the forum; sometimes I even call you my sensei. I forever dread the day you might step away from the game. I'd sacrifice my ownlife if it meant giving you a permanent +2 to your PSL.

You've given me so much joy and inspiration over the years. I remember when you hit a plateau with your looksmaxxing efforts—it was like my heart broke into a million pieces. But a tear still fell from my eye when I saw you push through with a new regimen, because deep down, my glorious king Clavicular never stops. I just wanted you to reach that next level. And finally, you did, my sweet aesthetics guru reached his peak and I rejoiced. 2024 was a rough year, but your transformation made history happen. You led the incels to the Promised Land of Becky's DMs, and I couldn't believe it.

I was crying, bawling even, when I read your post where you declared, 'BOUNCERMAXXING IS JUST THE BEGINNING!' Not only have you changed the game of looksmaxxing forever, but you've eternally changed my world. And even though you're bulking right now, we all know it's part of the master plan, my bloated yet beautiful king. I love you, my glorious king, Clavicular.

 

[Donkeyballs]

what about this doe? https://www.cdc.gov/nchhstp/director-letters/nlaad-2024.html

 

[Deleted member 87612]

this is a balding prevention mechanism?

 

[yue]

, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.

why would it not, shouldn't the upswing be equal to the downswing

 

[Rigged]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).
View attachment 3240353
I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.
View attachment 3240359
Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.
View attachment 3240366
The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

Finerenone

 

[Fartmaxxing]

order ELP from BG pharma it is really cheap

 

[Fartmaxxing]

why not hydrochlorothiazide

 

[Deleted member 26345]

DNR, your downfall will be swift when your kidney implodes

 

[Deleted member 80562]

Or just get off roids JFL

Girls don’t even care about muscles anyway

 

[lucifer6969]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).
View attachment 3240353
I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.
View attachment 3240359
Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.
View attachment 3240366
The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

buy it from india mart it is a legit site

https://www.google.com/url?sa=t&source=web&rct=j&opi=89978449&url=https://m.indiamart.com/proddetail/eplerenone-tablet-25-mg-2850328353691.html&ved=2ahUKEwjF3_PihJKJAxVJnq8BHccYINYQr4kDegQIGRAA&usg=AOvVaw2Zjq_2nYG-nopCQhvmlbEc

 

[Deleted member 77820]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).
View attachment 3240353
I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.
View attachment 3240359
Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.
View attachment 3240366
The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

Their is no fucking way
Are you reading my mind like wtf
Like everything i have learned just recently boom 1 week later you write a thread about it

 

[LooksmaxAutist]

If your goal is to induce diuresis and reduce reabsorption your best bet first off is sleeping with your body at a slope, at roughly a 5-10 degree decline, to induce the release of atrial natriuretic peptide. As far as long term use of diuretics is concerned if I was to use long term diuretics I would likely go with osmotic diuretics as it is safer and doesn't work through pharmacologic means reducing the risk, which does come with a trade off of being less effective. All of this considered your body does a good job of balancing water and minerals by itself usually with the proper intake of electrolytes. One thing I will say is do not fuck around with potassium sparing diuretics as if you mess up with these you can kill yourself via inhibition of heart activity due to excess potassium ions.

 

[DR. NICKGA]

I never get bloated, i got good genetics

 

[craven]

If your goal is to induce diuresis and reduce reabsorption your best bet first off is sleeping with your body at a slope, at roughly a 5-10 degree decline, to induce the release of atrial natriuretic peptide. As far as long term use of diuretics is concerned if I was to use long term diuretics I would likely go with osmotic diuretics as it is safer and doesn't work through pharmacologic means reducing the risk, which does come with a trade off of being less effective. All of this considered your body does a good job of balancing water and minerals by itself usually with the proper intake of electrolytes. One thing I will say is do not fuck around with potassium sparing diuretics as if you mess up with these you can kill yourself via inhibition of heart activity due to excess potassium ions.

cope dnr

 

[chan]

why not hydrochlorothiazide

I lowk stole mine and it's really effective but I recommend some lil bit of coffee on top of it

 

[Deleted member 86877]

Keep barking

 

[MUSTYCOPER]

I lowk stole mine and it's really effective but I recommend some lil bit of coffee on top of it

Legit, i take 2 g pottasium + 1 white monstor + 50 mg of hctz and debloat well + no sides at all , maybe dry eyes every now and the

 

[idkwhattoputhere]

head above feet?

If your goal is to induce diuresis and reduce reabsorption your best bet first off is sleeping with your body at a slope, at roughly a 5-10 degree decline, to induce the release of atrial natriuretic peptide. As far as long term use of diuretics is concerned if I was to use long term diuretics I would likely go with osmotic diuretics as it is safer and doesn't work through pharmacologic means reducing the risk, which does come with a trade off of being less effective. All of this considered your body does a good job of balancing water and minerals by itself usually with the proper intake of electrolytes. One thing I will say is do not fuck around with potassium sparing diuretics as if you mess up with these you can kill yourself via inhibition of heart activity due to excess potassium ions.

 

[LooksmaxAutist]

head above feet?

no feet above head, if you increase the amount of blood in the heart, specifically the right atrium, atrial naturistic peptide is released to which excretes water and salt to help reduce blood pressure. If you sleep with your legs above your head at an angle some of the blood that would have gone to your legs will end up in your heart and as a result cause your body to release ANP throughout sleep.

 

[chan]

why not hydrochlorothiazide

I lowk stole mine and it's really effective but I recommend some lil bit of coffee on top

Legit, i take 2 g pottasium + 1 white monstor + 50 mg of hctz and debloat well + no sides at all , maybe dry eyes every now and the

the side effects i experience are just a lil bit of a headache

 

[Sadist]

MCR Antagonists seem to be the only way to save yourself from becoming a subhuman aldosteronecel (test bloat).
View attachment 3240353
I have severe conns syndrome from 750mg of creatine in minecraft, so I hope to counteract this failo with MCR antagonists like EPLERENONE or spironolactone.
Eplerenone being the clear choice of the 2 for a multitude of reasons, but unfortunately its like 400$ per kilogram and you need 500mg+ to get the results from it.
View attachment 3240359
Loop diuretics like lasix are prob unhealthy overtime for your kidneys but EPL is much better for you as it just blocks aldosterone without depleting you of all electrolytes.
Lasix has its time and place for clubmaxing and needing a quick debloat in sub 2 hours. EPL is good for a sustained chiselmax

Spoiler: source about healthmax

https://dom-pubs.pericles-prod.literatumonline.com/doi/10.1111/dom.13393

Estimated long-term benefits of finerenone in heart failure

About The Study: In this prespecified secondary analysis of the FINEARTS-HF randomized clinical trial, long-term treatment with the nonsteroidal mineralocorticoid receptor antagonist finerenone was estimated to extend event-free survival by up to 3 years among people with heart failure with...

www.eurekalert.org

Another article claiming MCR antagonists increase lifespan by 3 years. So you get the best of both worlds in terms of chisel and health.
View attachment 3240366
The only issue is half life, but aldosterone shouldnt really rebound to quickly in theory so you can prob dose once per day.
Im looking into sources from china for a cheap bulk order but its brutally expensive atm

Gatekeeping the biggest looksmax - GTFIH

HOLY SHIT Eplerenone mogs so fucking hard. I took this shit and had 0 facial fluid in 4 hours. 25 MG daily and you will never bloat again, and its long term safe, you can perma blast it. Lasix is shilled on here a ton but you will go to the hospital from it ! It blocks aldosterone too making...

looksmax.org

I been trying it for ages but shit is so goshdarn expensive! I was coping hard with 25mg. Ill keep looking into other ways to antagonize MCR without breaking the bank.

Maybe @Dyorotic knows

dnrd