Anti anxiety/ social max substances.

BrahminBoss

BrahminBoss

God make my neurotransmitters great inc
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Taurine : Safe to combine with many drugs, increases both GABA and dopamine while decreasing glutamate, also has pro - liver and brain function, increase testosterone by functioning as antioxidant in testes. (9/10 A tier , safe as fuck, although you wont be extremely low inhib or anything ) anywhere from 1000- 2000 mg is probably maximising the anti anxiety component

Theanine: Found in tea, some say benefits peak at 300 mg and not much after, but some also advocate for a megadose. I personally dont have a strong opinion on dosage but it did seem like 600 mg was just a bit stronger in relaxing me than 300. Works similar to taurine, and also has some fat loss benefits by modulating gut bacteria and turning on brown adipose tissue. 7/10 , indispensable for most anti anxiety stacks as it synergises well. Works by reducing glutamate and serotonin.

Caffeine: While caffeine is often thought of as pro anxiety, ive found lower doses are actually anxiolytic (relieving anxiety) while higher doses increase it. Imo a small amount of caffeine with sugar and cream can releive anxiety as caffeine also has abundant doses of magnesium, antioxidants, anti opiods (4- caffeoyl quinide) and methyl xanthines which can promote alertness and urge for socialisation. (the classic red bull plus alcohol combo may exploit this by leveraging caffeine's pro alertness prop with alcohol's lower inhibition) - i give 6/10 as it may be hard to gauge the exact and sometimes maybe unpredictable reaction

AlcohoL: 6/10, reliably lowers inhib, is freely served etc but imo leads to lapses of judgement. I think best is to work up to a slight buzz (3-4 shots of vodka) and use the other substances I mentioned here beforehand so it synergises.

Lyrica: My intital impressions werent all that good, as it reliably lowers IQ by 10 points atleast even at 75 mg, however i think 30 mg (half of the capsule) can be used and it does lower inhib a bit without IQ and humour loss although it needs to be stacked w the others mentioned. DO NOT COMBINE WITH ALCOHOL, DO NOT REDOSE, DO NOT USE MORE THAN ONCE A WEEK"

Creatine: Works by increasing DHT and decreasing serotonin.

Magnesium Glycinate: Tried and tested drug, pop two of these and maybe eat some gelatin rich gummies 2 hours beforehand and youll again reliably lower inhib by a lot. Also great for sleep (unlike theanine which keeps me up a bit)

Valerian root: Havent tried it but it has decent reviews.

Kava: Youre not that guy.


Phenibut: Have not tried but seems to be great for all nighter in clubs etc. just dont drink and do it sparingly. If you get dependent dont quit cold turkey, taper off and use safer GABA agonists liek baclofen

Baclofen: Muscle relaxer, OTC in some places. 40 mg (60 depedning on body weight) will reliably lower inhib if you give it two hours ( most drugs in my list take 2 hours to come up and peak in 2-4 hours). Legal alternative to phenibut, (baclofen simply has an extra chlorine atom)

GHB: Supposed to be God tier but leads to addiction quick, if you do get a nice clean source which I doubt , research it before you do take it. DO NOT MIX WITH ALCOHOL, MAY RESULT IN DEATH.

Plain Old GABA: If you want to increase GABA, just take GABA lol! The idea that oral GABA does not get absorbed by the brain is false . You can take it or Gabapentin which is an anti epileptic.

Progesterone/ Allopregnenolone/ 7 keto DHEA: All these will reliably nuke anxiety, and 7 keto DHEA may even get you off your chair hyped and ready to socialise unlike high doses of alchol which will put you in slump. Do your reseatch on appropriate doses if you go ahead with thse.

White/ Green Kratom: Ive used it and it feels great, however I think probably not good for cold approaching/ it enhances socialisation when already comfortable but doesnt make you want to meet new people atleast in my experience. DO NOT MIX with alcohol.

T3: a small dose (say 5 mcg) of t3 is anti anxiety by reducing adrenaline/ increasing ATP output/ increase steroid synthesis/ detoxing estrogen/ increasing ability to store magnesium in cells/ water stabilsing etc etc. Taking t3 like a bodybuilder aka 25/50 mcg all at once will greatly increase anxiety and cause heart fibrosis. T3 needs to be dosed at a physiological dose (body makes around 4 mcg in 4 hours)

Sugar/potassium : Sometimes theyre all that;s needed

Microdosed LSD/ 4 aco DMT/ Shrooms: Has evidence it works if used long term and even offers some acute benefits.

DHT: If its a big night , using a few mg DHT wont really shut you down and you will notice a boost in libido/ mood/ reduction in anxiety etc.Use the gel form

Adaptogens like ashwagandha/ rodhiola/ Horny goat weed: Does work through phytochemicals/ plant steroids that can function to reduce anxiety/ increase libido etc , although needs to be cycled and benefits probably go away

Honorable mention:

Cigarettes: Smoking is the best convo starter and while it doesnt nuke anxiety in certain areas smoking can be reliable way to not come across as creep if ur not 6 psl plus.



No interest in SNRI, Vorinostat. If you need that shit to be low anxiety it never began. But you can do your research on those.

Btw im incel so do with that what you will.
 
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@n9wiff @incel194012940
 
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Good read, why off-topic though?
 
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Alpha GPC, Theanine, Magnesium glycinate and possibly caffeine

I need to start nootropics my family has a history of neurological disorders, especially bipolar disorder and seizures.
 
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ignoring the connotation of ashwagandha it reduces cortisol on average by 24% and boost cognitive function
 
ignoring the connotation of ashwagandha it reduces cortisol on average by 24% and boost cognitive function
I included ashwagandha in the adaptogenic sessions, sadly it also raises sertonin too much if done too often which is why it needs to be cycled.
 
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I included ashwagandha in the adaptogenic sessions, sadly it also raises sertonin too much if done too often which is why it needs to be cycled.
i have a genetic defect for me to get 50% or 2x less serotonin I forgot which so I think ashwagandha might be helping with that then
 
The only things that work from that list are Alcohol, GHB, phenibut
 
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The only things that work from that list are Alcohol, GHB, phenibut
well yea only TRT works for hypogonadal cels but most people are just average T and can probably get it up without blasting.
 
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Bones don’t lie

New short story📝!!!:


bones don’t lie” out August 17th, 2024 12:00 Pm EST

When millimeters of bone cheat you out of a good life, what then is laid out before you on the path ahead?

1200px-Meister_Francke_003.jpg

“Do Not Weep For I am Set Free”
 
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mf sits on his fat ass posting on incel forums all day, tf u need "socialmaxx" supplements for 💀💀💀
 
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mf sits on his fat ass posting on incel forums all day, tf u need "socialmaxx" supplements for 💀💀💀
I vc my Dravidian I need to get prepared for that
 
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i have a genetic defect for me to get 50% or 2x less serotonin I forgot which so I think ashwagandha might be helping with that then
Not sure about that is it MAOI related or tryptophan conversion
 
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Not sure about that is it MAOI related or tryptophan conversion
I forgot what it was I took a genetic test that shows all my abnormalities they were testing for I have the paper in a file box but that take forever to find
 
sanju
 
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I changed my mind on lyrica after trying a microdose of it rather tha bigger doses, @Michael Myers can u let me edit as this is a looksmax related post and kindly move to looksmax section?
 
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I changed my mind on lyrica after trying a microdose of it rather tha bigger doses, @Michael Myers can u let me edit as this is a looksmax related post and kindly move to looksmax section?
I can’t make you edit it but I can edit it. What do you want to add? I’ll move to Looksmax.
 
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bad guide, drank 41 monsters for taurine ended up losing a kidney
 
tbh absence of caffeine makes more more anxious than say a higher dose (3-4+ cups of coffee)
 
Brahmin bangers
 
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Cypro?
 
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Taurine : Safe to combine with many drugs, increases both GABA and dopamine while decreasing glutamate, also has pro - liver and brain function, increase testosterone by functioning as antioxidant in testes. (9/10 A tier , safe as fuck, although you wont be extremely low inhib or anything ) anywhere from 1000- 2000 mg is probably maximising the anti anxiety component

Theanine: Found in tea, some say benefits peak at 300 mg and not much after, but some also advocate for a megadose. I personally dont have a strong opinion on dosage but it did seem like 600 mg was just a bit stronger in relaxing me than 300. Works similar to taurine, and also has some fat loss benefits by modulating gut bacteria and turning on brown adipose tissue. 7/10 , indispensable for most anti anxiety stacks as it synergises well. Works by reducing glutamate and serotonin.

Caffeine: While caffeine is often thought of as pro anxiety, ive found lower doses are actually anxiolytic (relieving anxiety) while higher doses increase it. Imo a small amount of caffeine with sugar and cream can releive anxiety as caffeine also has abundant doses of magnesium, antioxidants, anti opiods (4- caffeoyl quinide) and methyl xanthines which can promote alertness and urge for socialisation. (the classic red bull plus alcohol combo may exploit this by leveraging caffeine's pro alertness prop with alcohol's lower inhibition) - i give 6/10 as it may be hard to gauge the exact and sometimes maybe unpredictable reaction

AlcohoL: 6/10, reliably lowers inhib, is freely served etc but imo leads to lapses of judgement. I think best is to work up to a slight buzz (3-4 shots of vodka) and use the other substances I mentioned here beforehand so it synergises.

Lyrica: My intital impressions werent all that good, as it reliably lowers IQ by 10 points atleast even at 75 mg, however i think 30 mg (half of the capsule) can be used and it does lower inhib a bit without IQ and humour loss although it needs to be stacked w the others mentioned. DO NOT COMBINE WITH ALCOHOL, DO NOT REDOSE, DO NOT USE MORE THAN ONCE A WEEK"

Creatine: Works by increasing DHT and decreasing serotonin.

Magnesium Glycinate: Tried and tested drug, pop two of these and maybe eat some gelatin rich gummies 2 hours beforehand and youll again reliably lower inhib by a lot. Also great for sleep (unlike theanine which keeps me up a bit)

Valerian root: Havent tried it but it has decent reviews.

Kava: Youre not that guy.


Phenibut: Have not tried but seems to be great for all nighter in clubs etc. just dont drink and do it sparingly. If you get dependent dont quit cold turkey, taper off and use safer GABA agonists liek baclofen

Baclofen: Muscle relaxer, OTC in some places. 40 mg (60 depedning on body weight) will reliably lower inhib if you give it two hours ( most drugs in my list take 2 hours to come up and peak in 2-4 hours). Legal alternative to phenibut, (baclofen simply has an extra chlorine atom)

GHB: Supposed to be God tier but leads to addiction quick, if you do get a nice clean source which I doubt , research it before you do take it. DO NOT MIX WITH ALCOHOL, MAY RESULT IN DEATH.

Plain Old GABA: If you want to increase GABA, just take GABA lol! The idea that oral GABA does not get absorbed by the brain is false . You can take it or Gabapentin which is an anti epileptic.

Progesterone/ Allopregnenolone/ 7 keto DHEA: All these will reliably nuke anxiety, and 7 keto DHEA may even get you off your chair hyped and ready to socialise unlike high doses of alchol which will put you in slump. Do your reseatch on appropriate doses if you go ahead with thse.

White/ Green Kratom: Ive used it and it feels great, however I think probably not good for cold approaching/ it enhances socialisation when already comfortable but doesnt make you want to meet new people atleast in my experience. DO NOT MIX with alcohol.

T3: a small dose (say 5 mcg) of t3 is anti anxiety by reducing adrenaline/ increasing ATP output/ increase steroid synthesis/ detoxing estrogen/ increasing ability to store magnesium in cells/ water stabilsing etc etc. Taking t3 like a bodybuilder aka 25/50 mcg all at once will greatly increase anxiety and cause heart fibrosis. T3 needs to be dosed at a physiological dose (body makes around 4 mcg in 4 hours)

Sugar/potassium : Sometimes theyre all that;s needed

Microdosed LSD/ 4 aco DMT/ Shrooms: Has evidence it works if used long term and even offers some acute benefits.

DHT: If its a big night , using a few mg DHT wont really shut you down and you will notice a boost in libido/ mood/ reduction in anxiety etc.Use the gel form

Adaptogens like ashwagandha/ rodhiola/ Horny goat weed: Does work through phytochemicals/ plant steroids that can function to reduce anxiety/ increase libido etc , although needs to be cycled and benefits probably go away

Honorable mention:

Cigarettes: Smoking is the best convo starter and while it doesnt nuke anxiety in certain areas smoking can be reliable way to not come across as creep if ur not 6 psl plus.



No interest in SNRI, Vorinostat. If you need that shit to be low anxiety it never began. But you can do your research on those.

Btw im incel so do with that what you will.
What should I abuse from this list which helps mood and T
 
Phenibut used to be goat but doesn’t work anymore for me, even after a few months off. Idk if the formula changed (I had to change vendors and lift mode stopped selling it) or what. But judging from everyone on Reddit complaining it’s no longer working too, I think something changed
 
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same shit for me, what about selegiline 2.5mg sublingual ?
I stopped it as it is prone to interaction w other substances , but if ur not using anything else it may work ( more for sociability than anxiety tho although latter also improves )
 
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I stopped it as it is prone to interaction w other substances , but if ur not using anything else it may work ( more for sociability than anxiety tho although latter also improves )
pregaba/Kratom = god mode
 
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Good thread OP but for nootropic purposes I think low-dose fluvoxamine should be included (50mg) should be included because of sigma-1 agonism, 5ht1a desensitisation and indirect 5ht3 antagonism. It’s also an open channel blocker of NMDA receptors and does so in a voltage-dependant manner, and has been shown to increase BDNF. Very good for increasing the dopaminergic effects of low dose amphetamine, especially if combined with a MAO-B inhibitor (also low dose) like Xadoga or Selegiline, or a reverse MAO-A inhibitor like moclobemide if you want the noradrenergic effects too.

Bupropion would be another good option to combine with low dose amphetamine and fluvoxamine. Possibly Quetiapine to enhance the dopaminergic and glutamatergic modulating effects of Luvox too.

Some other drugs/supps that should be included are memantine, taurine, lamictal, ginkgo, schisandra, glycine, NAC. Plus, here’s some extra info on the benefits of creatine:

**• Creatine can specifically bind to the benzodiazepine binding site of the GABA-A receptor, leading to increased GABAergic activity in certain brain regions.**

[*”The multiple benefits of supplementary creatine arise from the fact that the creatine-phosphocreatine [PCr] system has physiologically important roles that include maintenance of intracellular ATP and acid–base balance, post-ischaemic recovery of protein synthesis, cerebral vasodilation, antioxidant actions, and stabilisation of lipid membranes. In the brain, creatine not only reduces lipid peroxidation and improves cerebral perfusion, its interaction with the benzodiazepine site of the GABAA receptor is likely to counteract the effects of glutamate excitotoxicity.”*](https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/1471-2393-14-150)

**• Creatine supplementation reduces cortical glutamate concentration, which is thought to play a role in neuronal degeneration. By lowering excessive glutamate levels, creatine may help protect neurons.**


[*”Concussion and a TBI alter the release of the excitatory amino acid glutamate that over activates the N-methyl-D-aspartate receptor, leading to an excitotoxic cascade including increasing cellular calcium (Ca2+), neuronal death, damage, and dysfunction [12, 58, 59]. In a rodent primary embryonal hippocampal and cortical cell culture model (> 99% neuronal, < 1% glial) that was challenged by glutamate or H2O2, the presence of creatine (5 mM) enhanced cellular energy and bioenergetics, reduced oxidative stress, and attenuated the Ca2+ response to N-methyl-D-aspartate receptor stimulation [60]”** - **”In addition to delaying motor deficits and extending survival, Andreassen et al. [106] observed that creatine supplementation reduced cortical glutamate concentration, which is thought to play a role in neuron degeneration and death. If so, these findings may provide some evidence for the potential mechanistic role for how creatine contributes to increased longevity and improved motor performance.”*](https://link.springer.com/article/10.1007/s40279-023-01870-9)


**• Creatine found to be neuroprotective for dopaminergic neurons, protecting them against neurotoxic and metabolic insults. Also increases GABA receptor density through its activity as a neuromodulator.**

[*”The hippocampal enzyme glutamic acid decarboxylase 67, which is responsible for over 90% of GABA production in the CNS, was downregulated after TBI. Nevertheless, this effect was reversed by creatine supplementation ( 28 ). These reports declare that creatine is able to maintain the GABAergic tonus and maintain the GABA-mediated synaptic inhibition in the brain. Moreover, studies have revealed that chronic creatine supplementation treatment results in a moderate enhancement in the density of GABA neurons in spinal cord cultures ( 31 ).”*](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10787915/)

**• Has an agonist effect on GABA receptors, and may act as a neurotransmitter in the central nervous system.**
- https://www.futuremedicine.com/doi/10.2217/cnc-2016-0016

**• More information from a study - and keep in mind much more research needs to be done on this topic but nevertheless I find these results rather intriguing - exploring the neuroprotective properties and neurobiological mechanisms of creatine. Thereby showing its promising potential for use as an adjunct treatment for psychiatric diseases and other CNS abnormalities.**

[*”Dietary creatine confers neuroprotection against a range of toxic substances and can minimize physical damage from traumatic insults in rodent models of disease (Brustovetsky et al., 2001; Matthews et al., 1998; 1999; Sullivan et al., 2000; Roy et al., 2002). The proposed mechanisms underlying these effects include the ability of creatine to increase energy availability, to promote neuronal proliferation and survival, and to reduce oxidative stress, apoptosis and necrosis of neurons (Andres et al., 2005; Brdiczka et al., 1998; Dolder et al., 2003; Ducray et al., 2007a, b; Lawler et al., 2001; Sestilli et al., 2006, 2011). The antioxidant effects of creatine are one plausible neurobiological mechanism for the treatment of psychiatric disease. Metabolic disturbances in the frontal and limbic regions have been described for schizophrenia, mood and anxiety disorders (see Section 4.2.). Briefly, a decline in ATP concentrations, which is typically observed in psychiatric illness, leads to an accumulation of intracellular calcium (Ca2+), the formation of radical and reactive oxygen species, and ultimately mitochondrial damage from oxidative stress. Creatine supplementation prevents oxidative damage through direct antioxidant activity in mammalian cell cultures (Lawler et al., 2002; Sestili et al., 2006; Young et al., 2010). Creatine also has a neuromodulatory function in the CNS, and may influence neurotransmitter systems or neuroplasticity factors associated with mental illness. Evidence indicates that creatine can be released in an excitotic, action-potential dependent manner in response to membrane depolarization (Almeida et al., 2006). Specifically, researchers have demonstrated that depolarization of rat brain tissue produced an influx of Ca2+ and then subsequent release of creatine. When Ca2+ was not present or when Na+ channels were blocked by tetrodotoxin, creatine was not released. This is usually typical of neurotransmitter release. This and other work indicates that creatine acts as a partial agonist of central GABAA receptors (Almeida et al., 2006; Koga et al., 2005), and creatine has also been shown to modify NMDA receptor activity (Oliveira et al., 2008; Royes et al., 2008). Other evidence has suggested creatine is related to serotonin and dopamine (Agren and Niklasson, 1988; Allen et al., 2010; Andres et al., 2005).”*](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340488/)
 
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i have a genetic defect for me to get 50% or 2x less serotonin I forgot which so I think ashwagandha might be helping with that then
Supp with 5htp
 
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Some other drugs/supps that should be included are memantine, taurine, lamictal, ginkgo, schisandra, glycine, NAC.
Jfl misread taurine as something else
 
I dead got a method that is rarely mentioned on dis forum I might drop it for dat lifetime vip 🤑
 
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Phenibut works really well for me even at low dose (250mg)
 
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i forgot to mention positive allosteric modulators of GABA will probably let you have lower baseline anxiety even after coming off thse substances so taurine, and prog should maybe be high in the list or androsterone mayb? @7zyzz7 @incel194012940
 
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One of the best threads very useful,gonna be trying some of this stuff to,to try fraud nt better
 

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