teenagelovepilldnr
Iron
- Joined
- Nov 4, 2025
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why I think stacking MK + real HGH is actually mogger and not redundant (unlike stacking test + SARMs):
1. Different mechanisms = synergy
- MK-677 is a oral ghrelin receptor agonist → spikes pulsatile GH release via pituitary + ↑ IGF-1 through natural pathway
- Exogenous HGH is direct recombinant 191aa → gives constant baseline elevation, blunts the natural pulses a bit but still mogs any secretagogue alone
2. HGH does NOT shut down your natural GH like test shuts down test
Negative feedback on exogenous HGH mainly hits GHRH, but ghrelin pathway (MK-677) is way less suppressed. Studies show when you add a GHRP/GH secretagogue on top of HGH injections you still get additional pulses and higher IGF-1 than HGH solo (Rudman 1990, Rahim 1998, etc.)
3. Real world data & bloodwork from vets
Guys pulling 20-30 mg pharma + 25 mg MK nightly are hitting IGF-1 levels of 800-1100 ng/mL consistently while guys on 8-10 IU HGH alone usually cap around 600-750. That’s literally 40-50 % higher IGF for basically no extra sides except a bit more water and hunger.
4. Practical benefits for looksmax
- Higher IGF-1 = better facial bloat recovery? No, actually faster collagen synthesis, better skin thickness, more pronounced bone remodeling if you’re sub-25
- Constant baseline from HGH + huge nocturnal pulses from MK = round-the-clock anabolism, better sleep, insane recovery
5. Sides are basically the same
You’re already getting lethargy/water from HGH, MK just adds appetite (which is good when you’re trying to lean bulk or heightmax fuel)
TLDR: Not the same pathway as TRT + RAD where you nuke natural test. This is like TRT + HCG for GH/IGF axis. You get the baseline elevation + still keep big natural pulses → skyhigh IGF-1 = maximum forward growth / frame / face gains.
Thoughts? Anyone running this stack right now drop bloods (pre and on cycle IGF-1) would be legendary.
1. Different mechanisms = synergy
- MK-677 is a oral ghrelin receptor agonist → spikes pulsatile GH release via pituitary + ↑ IGF-1 through natural pathway
- Exogenous HGH is direct recombinant 191aa → gives constant baseline elevation, blunts the natural pulses a bit but still mogs any secretagogue alone
2. HGH does NOT shut down your natural GH like test shuts down test
Negative feedback on exogenous HGH mainly hits GHRH, but ghrelin pathway (MK-677) is way less suppressed. Studies show when you add a GHRP/GH secretagogue on top of HGH injections you still get additional pulses and higher IGF-1 than HGH solo (Rudman 1990, Rahim 1998, etc.)
3. Real world data & bloodwork from vets
Guys pulling 20-30 mg pharma + 25 mg MK nightly are hitting IGF-1 levels of 800-1100 ng/mL consistently while guys on 8-10 IU HGH alone usually cap around 600-750. That’s literally 40-50 % higher IGF for basically no extra sides except a bit more water and hunger.
4. Practical benefits for looksmax
- Higher IGF-1 = better facial bloat recovery? No, actually faster collagen synthesis, better skin thickness, more pronounced bone remodeling if you’re sub-25
- Constant baseline from HGH + huge nocturnal pulses from MK = round-the-clock anabolism, better sleep, insane recovery
5. Sides are basically the same
You’re already getting lethargy/water from HGH, MK just adds appetite (which is good when you’re trying to lean bulk or heightmax fuel)
TLDR: Not the same pathway as TRT + RAD where you nuke natural test. This is like TRT + HCG for GH/IGF axis. You get the baseline elevation + still keep big natural pulses → skyhigh IGF-1 = maximum forward growth / frame / face gains.
Thoughts? Anyone running this stack right now drop bloods (pre and on cycle IGF-1) would be legendary.
