Cjc dac hype

[reidm10Z!]

What is the hype over cjc no dac im curious why everyone prefers it, its more expensive to run for a while you need to pin more and its half life literally can go as low as 30 minutes the drug affinity complex and literally last an entire week and u get a higher gh and igf output over time.

 

[jflwarrior05]

DAC - as a drug affinity complex means that it will be for longer periods of time in your blood, because of binding to albumins and other less significant blood proteins. I guess the hype is about the fact that Cjc no DAC "mimmics the natural release" of the GHRH. The issue with DAC is that it can lead to desensitization of GHRH-R (growth hormone releasing hormone receptors) that you target with CJC and lower the physiological response.

 

[reidm10Z!]

DAC - as a drug affinity complex means that it will be for longer periods of time in your blood, because of binding to albumins and other less significant blood proteins. I guess the hype is about the fact that Cjc no DAC "mimmics the natural release" of the GHRH. The issue with DAC is that it can lead to desensitization of GHRH-R (growth hormone releasing hormone receptors) that you target with CJC and lower the physiological response.

Yeah but what’s the point if you can go average doses for maybe 4 months max of it with the drug affinity complex the desensitization probably won’t even happen

 

[jflwarrior05]

That's why it's just lowering the risk and not eliminating it completly. CJC is a research chemical rather than regular pharmaceutical so we don't know that much about it. What I wrote is just the general rule when it comes to G protein receptors (which GHRH-R is). When receptor is phosphorylated too much or too often beta-arrestine causes it to internalize lowering the number of available receptors. Lot of physiology and other stuff. TLDR: You pin more, because you assume it will happen.

 

[reidm10Z!]

That's why it's just lowering the risk and not eliminating it completly. CJC is a research chemical rather than regular pharmaceutical so we don't know that much about it. What I wrote is just the general rule when it comes to G protein receptors (which GHRH-R is). When receptor is phosphorylated too much or too often beta-arrestine causes it to internalize lowering the number of available receptors. Lot of physiology and other stuff. TLDR: You pin more, because you assume it will happen.

Okay yeah true but why not take the risk with dac doesn’t the Desensitization go away after a somewhat short amount of time I don’t think it’s true but a few months?

 

[jflwarrior05]

That's up to you

 

[reidm10Z!]

That's up to you

Have you done either?

 

[jflwarrior05]

Have you done either?

No I haven't and I don't think I will. When it comes to compounds that alternate anabolic pathways I try to avoid it and find other solution. I don't know if I am overly cautious since GHRH mimmicing peptides can only boost GH/IGF-1 x1.5-x2 times so much less than regular HGH injections. Everything comes with risk, you can slay stacies or get hepatocarcinoma. I thought about MT-2 tho, but it is still just a thought.

 

[reidm10Z!]

No I haven't and I don't think I will. When it comes to compounds that alternate anabolic pathways I try to avoid it and find other solution. I don't know if I am overly cautious since GHRH mimmicing peptides can only boost GH/IGF-1 x1.5-x2 times so much less than regular HGH injections. Everything comes with risk, you can slay stacies or get hepatocarcinoma. I thought about MT-2 tho, but it is still just a thought.

Mt-2 is kinda weird I would use it but I heard it makes u nauseous and comes with a bunch of other weird stuff like libido not super crazy plus hyperpigmentation but I don’t think that’s super common.

 

[jflwarrior05]

Mt-2 is kinda weird I would use it but I heard it makes u nauseous and comes with a bunch of other weird stuff like libido not super crazy plus hyperpigmentation but I don’t think that’s super common.

With libido I read it's opposite, it's higher. My only concern is uncertainty about the link between melatonan (1 and 2) and melanoma. But I don't mind nausea, neoplasms on the other hand........

 

[reidm10Z!]

With libido I read it's opposite, it's higher. My only concern is uncertainty about the link between melatonan (1 and 2) and melanoma. But I don't mind nausea, neoplasms on the other hand........

I would use it but maybe only once spring starts at the least, I feel like it would look weird during the winter especially since everyone is pale but coloring lowkey ascends me so much lowkey.