Collagenmaxxing / The Epidermal Pharmacopoeia

[Sator]

• 5-ARI
  • (a.) Dutasteride: 0.5-2.5mg
  • (b.) Finasteride: 1mg
    • Desc. DHT upregulates expression of matrix metalloproteinases; specifically MMP-1, MMP-2, and MMP-9. MMPs kill collagen and elastin. Preventing DHT production can protect elastin and collagen from MMPs. Finasteride - targets type I 5α-reductase enzyme. Dutasteride - targets type II 5α-reductase enzymes. Dutasteride is more potent and more systemic than finasteride
• α-Ketoglutarate (AKG)
  • Calcium-Alpha Ketoglutarate (Ca-AKG)
    • 1g
      • Pair w/ vitamin C and vitamin K (K, if using calcium form)
        • Desc. Enhances collagen synthesis + prevents gray hair
• Astaxanthin
  
  • Haematococcus pluvialis extract not synthetic
    • Take w/ high-fat repast
      • 12-24mg
        • Desc. Enhances skin color (i.e. glow), protects skin from UV damage, reduces inflammation and oxidative stress. Collagen stimulator when paired w/ hydrolyzed peptides
• Collagen
  
  • Hydrolysate / hydrolyzed / peptides
    • Type: I, III
      • Bovine
        • Grass-fed
          • Max. 153-200mg / kg bodyweight
            • Min. 1g / 10kg bodyweight
              • Desc. Places collagen fragments (hydrolyzed peptides / hydrolysate) in the bloodstream which signal to the epidermis to stimulate collagen
• Glucosamine
  • Glucosamine sulfate
    • 1-1.8g
      • Desc. Inhibits matrix metalloproteinases ((MMPs) enzymes that kill collagen and elastin)
• Glycine
  
  • 1-2g if already supplementing collagen
    • Desc. Amino acid building block of collagen
• Heliocare (Polypodium Leucotomos Extract)
  
  • 240mg
    • Desc. Patented plant extract (Fernblock) that's clinically shown to act as an oral sunblock. Effective only when paired w/ SPF (ideally broad-spec. SPF 50+ PA++++)
• Hyaluronic Acid
  • High-molecular weight
    • 200mg
      • Desc. Increases hyaluronic acid found in the skin, enhances epidermal hydration = aesthetic appearance + mildly reduces wrinkles
• Isotretinoin (Accutane)
  
  • Low-dose (10mg)
    • 2-3x / week
      • Don't take w/ vitamin A
        • Desc. increases collagen production
• Magnesium
  
  • Magnesium Malate
    • 1-2g (300-400mg magnesium, rest malate)
      • Desc. Collagen precursor
• Niacin (Vitamin B3)
  
  • Flush-form
    
    • 50-100mg
      • Desc. Enhances epidermal appearance
• NutraKOS (HY6AA)
  • 1x / day
    • Desc. Oral form of SuneKOS (injection): a patended blend of hyaluronic acids and amino acids. Increases elastin, fibronectin, and expression of collagen types IV and VII (types not found in other collagen supplements). SuneKOS can increase collagen expression six months after a single post-op
• Orthosilicic Acid (Biosil)
  • 1x / day
    • Desac. Patented collagen stimulator and protector. Neutralizes homocysteine (destroys collagen) like TMG
• Probiotics
  
  • ≥25,000,000,000CFU
    • Desc. Reduce MMP activity
• Pyncogenol (French Maritime Pine Bark Extract)
  • 50-100mg
    • Desc. Collagen stimulator
• Vitamin A
  • Don't take vitamin A w/ isotretinoin
    • Retinyl Palmitate
      • ≤50,000IU
        • Desc. Efficacious in reducing appearance of UV-damaged skin
• Vitamin C
  
  • Liposomal or ascorbic acid
    • 100-1000mg (if taking 1000mg, split dose throughout the day, not all at once)
      • Desc. Antioxidant and collagen precursor
• Zinc
  • Zinc gluconate, glycinate, or picolinate
    • Pair w/ low-dose copper, take each supplement at different times (copper and zinc inhibit each other's absorption)
      • 15-25mg
        • Desc. Collagen precursor

 

[hungrythanos414]

w post bhai...this is my collagen maxxing routine: Bone broth + collagen peptides, ghk-cu(200mcg inject daily), tret(.01), spf broad spectrum mineral 50+, folic acid(b5), magnesium(glycinate) + melatonin(1mg), primal diet, raw liver weakly, niacinamide + hyaluronic acid serum at night, derma stamp occasionally when i am not breaking out. Lmk what i should add. Also DO i just hop on Accutane apt, my acne doesnt go away bc of acting hormones. Lmk, any advice would be appreciated.

 

[Sator]

w post bhai...this is my collagen maxxing routine: Bone broth + collagen peptides, ghk-cu(200mcg inject daily), tret(.01), spf broad spectrum mineral 50+, folic acid(b5), magnesium(glycinate) + melatonin(1mg), primal diet, raw liver weakly, niacinamide + hyaluronic acid serum at night, derma stamp occasionally when i am not breaking out. Lmk what i should add. Also DO i just hop on Accutane apt, my acne doesnt go away bc of acting hormones. Lmk, any advice would be appreciated.

Is your routine budgeted or flexible? If on a budget, stick to the necessities like collagen peptides, tretinoin, and especially SPF. If your budget is flexible, you can incorporate every supplement I mentioned (which is also what I currently use). I will be making another collagenmaxxing guide that isn't on supplements at a later date.

Also, I would ditch the hyaluronic acid serum unless you live in a rainforest or you have a humidifier that's running next to you after every application. Application of exogenous hyaluronic acid serum will draw water from your dermis (inner layer of skin) to plump up your epidermis (outer layer); thus drying your skin out. A better alternative would be polyglutamic acid or oral hyaluronic acid.

I find copper peptides to be a last resort treatment. Not sure what your case is, but GHK-Cu can make the skin look worse if overused.

You should have a humidifier in your bedroom regardless of skincare and if you live in a cold environment. You should also invest in a form of red light therapy that has a wavelength of anywhere between 605-690 nanometers for 20 minutes a day and use it after each microneedling / dermastamp session, or any form of exfoliation for that matter.

Definitely add slugging to your evening routine. Basically use any non-comedogenic oil on your face so your face is shiny (squalene >>>) and you'll wake up with excellent skin.

Btw, does your SPF give you a cast when you apply it?

 

[20/04/2008]

• 5-ARI
  • (a.) Dutasteride: 0.5-2.5mg
  • (b.) Finasteride: 1mg
    • Desc. DHT upregulates expression of matrix metalloproteinases; specifically MMP-1, MMP-2, and MMP-9. MMPs kill collagen and elastin. Preventing DHT production can protect elastin and collagen from MMPs. Finasteride - targets type I 5α-reductase enzyme. Dutasteride - targets type II 5α-reductase enzymes. Dutasteride is more potent and more systemic than finasteride
• α-Ketoglutarate (AKG)
  • Calcium-Alpha Ketoglutarate (Ca-AKG)
    • 1g
      • Pair w/ vitamin C and vitamin K (K, if using calcium form)
        • Desc. Enhances collagen synthesis + prevents gray hair
• Astaxanthin
  
  • Haematococcus pluvialis extract not synthetic
    • Take w/ high-fat repast
      • 12-24mg
        • Desc. Enhances skin color (i.e. glow), protects skin from UV damage, reduces inflammation and oxidative stress. Collagen stimulator when paired w/ hydrolyzed peptides
• Collagen
  
  • Hydrolysate / hydrolyzed / peptides
    • Type: I, III
      • Bovine
        • Grass-fed
          • Max. 153-200mg / kg bodyweight
            • Min. 1g / 10kg bodyweight
              • Desc. Places collagen fragments (hydrolyzed peptides / hydrolysate) in the bloodstream which signal to the epidermis to stimulate collagen
• Glucosamine
  • Glucosamine sulfate
    • 1-1.8g
      • Desc. Inhibits matrix metalloproteinases ((MMPs) enzymes that kill collagen and elastin)
• Glycine
  
  • 1-2g if already supplementing collagen
    • Desc. Amino acid building block of collagen
• Heliocare (Polypodium Leucotomos Extract)
  
  • 240mg
    • Desc. Patented plant extract (Fernblock) that's clinically shown to act as an oral sunblock. Effective only when paired w/ SPF (ideally broad-spec. SPF 50+ PA++++)
• Hyaluronic Acid
  • High-molecular weight
    • 200mg
      • Desc. Increases hyaluronic acid found in the skin, enhances epidermal hydration = aesthetic appearance + mildly reduces wrinkles
• Isotretinoin (Accutane)
  
  • Low-dose (10mg)
    • 2-3x / week
      • Don't take w/ vitamin A
        • Desc. increases collagen production
• Magnesium
  
  • Magnesium Malate
    • 1-2g (300-400mg magnesium, rest malate)
      • Desc. Collagen precursor
• Niacin (Vitamin B3)
  
  • Flush-form
    
    ​
    • 50-100mg
      • Desc. Enhances epidermal appearance
• NutraKOS (HY6AA)
  • 1x / day
    • Desc. Oral form of SuneKOS (injection): a patended blend of hyaluronic acids and amino acids. Increases elastin, fibronectin, and expression of collagen types IV and VII (types not found in other collagen supplements). SuneKOS can increase collagen expression six months after a single post-op
• Orthosilicic Acid (Biosil)
  • 1x / day
    • Desac. Patented collagen stimulator and protector. Neutralizes homocysteine (destroys collagen) like TMG
• Probiotics
  
  • ≥25,000,000,000CFU
    • Desc. Reduce MMP activity
• Pyncogenol (French Maritime Pine Bark Extract)
  • 50-100mg
    • Desc. Collagen stimulator
• Vitamin A
  • Don't take vitamin A w/ isotretinoin
    • Retinyl Palmitate
      • ≤50,000IU
        • Desc. Efficacious in reducing appearance of UV-damaged skin
• Vitamin C
  
  • Liposomal or ascorbic acid
    • 100-1000mg (if taking 1000mg, split dose throughout the day, not all at once)
      • Desc. Antioxidant and collagen precursor
• Zinc
  • Zinc gluconate, glycinate, or picolinate
    • Pair w/ low-dose copper, take each supplement at different times (copper and zinc inhibit each other's absorption)
      • 15-25mg
        • Desc. Collagen precursor

Its good
You just screwed the dosages
The compound you promote are legit

 

[Sator]

Its good
You just screwed the dosages
The compound you promote are legit

Which dosages