
idkmanimao
𝐂𝐀𝐈 𝐂𝐫𝐞𝐰 𝐌𝐞𝐦𝐛𝐞𝐫
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- Feb 20, 2025
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By @Proex and @idkmanimao
Datura blocks muscarinic acetylcholine receptors in the brain. These are involved in overthinking, shame response, self-monitoring, and internal speech.
This will shut down your default mode network (DMN). That’s the part of your brain making you socially anxious and overly self-aware.
It removes your filter to simplify it. No more overanalyzing. No more “what if I look weird.”
Researchers have already sequenced the Datura stramonium genome. They found multiple duplications of tropane alkaloid biosynthesis genes.
The exact ones that produce the inhibition-killing scopolamine and atropine.
Other studies confirm: scopolamine crosses the blood-brain barrier and directly impacts the hippocampus, cortex, and reticular formation.
-in short, it gets rid of your inhibition.
https://www.sciencedirect.com/science/article/abs/pii/S0944711321001641
https://www.nature.com/articles/s41467-023-37133-4.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC10343631/
https://www.mdpi.com/2076-3921/10/8/1291
Weed- makes most people's inhibitions worse.
https://en.wikipedia.org/wiki/Depol...pression_of_inhibition?utm_source=chatgpt.com
SSRis- Blunts emotion, not inhibition. https://pubmed.ncbi.nlm.nih.gov/11110015/
Phenibut- Good for verbal output, but obvious. https://pubmed.ncbi.nlm.nih.gov/11830761/
Testosterone- helps with baseline emotions and self anxiousness (fucks some people up after cycle sometimes) https://pubmed.ncbi.nlm.nih.gov/27448713/
Datura- shuts down your inhibition. https://pubmed.ncbi.nlm.nih.gov/30192928/
“Tl; dr: Smoked dried flowers of Datura at an ancient Shiva temple, had a very pleasant experience. The only discomfort was dry mouth.”
https://www.erowid.org/experiences/exp.php?ID=114609&utm_source=chatgpt.com
“I have had depression, anxiety, and social anxiety all my life. I have been using Datura for the last 3 months, and it helps a lot.”
https://www.erowid.org/experiences/exp.php?ID=7842&utm_source=chatgpt.com
“Today is Tuesday, July 3rd 2001. Last Thursday was the best 19 hours of my life.”
“Users report a temporary removal of social inhibitions and filters, leading to a state where speech flows unfiltered and spontaneous social interactions become effortless.”
“When dosed carefully, Datura can serve as a powerful tool to explore unconscious thoughts and suppressed emotions.”
“Anecdotally, Datura has been described as a ‘neurochemical reset’ by some, helping to temporarily wipe the slate clean of habitual mental patterns, including social anxiety and inhibition.”
@Proex who helped make this thread has taken datura a week ago in this thread:
looksmax.org
he found datura in his grandma's yard, most of you inkwells can do the same.
His trip report:
For his trip he only used 20 seeds, even tho it's a small amount he says it helped him dramatically,
He took the seeds at 3am by soaking them in water and then drinking it.
1h latter he started spewing nonsense to me in this thread:
https://looksmax.org/threads/alrmo-i-hope-you-took-the-fogs.1542022/
He then left the forum cause he was feeling scared at 5am and experienced first signs of delirium
His mouth was dry, he constantly went to the toilet and his heart was pounding at first but then he could barely walk and he started seeing imaginary mosquitos.
He reported smoking an imaginary cig
And then a shadow of @MoggerGaston that looks like the pic bellow
Then he went to bed and had crazy dreams.
The shit is no joke,
but after this he reported very low inhib,
he could finally talk to foids on the street and was outside much more often,
it's like this trip made him an extrovert, this is the best drug since test tbh.
@Proex @Mainlander @Copercel
Datura blocks muscarinic acetylcholine receptors in the brain. These are involved in overthinking, shame response, self-monitoring, and internal speech.
This will shut down your default mode network (DMN). That’s the part of your brain making you socially anxious and overly self-aware.
It removes your filter to simplify it. No more overanalyzing. No more “what if I look weird.”
Researchers have already sequenced the Datura stramonium genome. They found multiple duplications of tropane alkaloid biosynthesis genes.
The exact ones that produce the inhibition-killing scopolamine and atropine.
Other studies confirm: scopolamine crosses the blood-brain barrier and directly impacts the hippocampus, cortex, and reticular formation.
-in short, it gets rid of your inhibition.
https://www.sciencedirect.com/science/article/abs/pii/S0944711321001641
https://www.nature.com/articles/s41467-023-37133-4.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC10343631/
https://www.mdpi.com/2076-3921/10/8/1291
Weed- makes most people's inhibitions worse.
https://en.wikipedia.org/wiki/Depol...pression_of_inhibition?utm_source=chatgpt.com
SSRis- Blunts emotion, not inhibition. https://pubmed.ncbi.nlm.nih.gov/11110015/
Phenibut- Good for verbal output, but obvious. https://pubmed.ncbi.nlm.nih.gov/11830761/
Testosterone- helps with baseline emotions and self anxiousness (fucks some people up after cycle sometimes) https://pubmed.ncbi.nlm.nih.gov/27448713/
Datura- shuts down your inhibition. https://pubmed.ncbi.nlm.nih.gov/30192928/
“Tl; dr: Smoked dried flowers of Datura at an ancient Shiva temple, had a very pleasant experience. The only discomfort was dry mouth.”
https://www.erowid.org/experiences/exp.php?ID=114609&utm_source=chatgpt.com
“I have had depression, anxiety, and social anxiety all my life. I have been using Datura for the last 3 months, and it helps a lot.”
https://www.erowid.org/experiences/exp.php?ID=7842&utm_source=chatgpt.com
“Today is Tuesday, July 3rd 2001. Last Thursday was the best 19 hours of my life.”
“Users report a temporary removal of social inhibitions and filters, leading to a state where speech flows unfiltered and spontaneous social interactions become effortless.”
“When dosed carefully, Datura can serve as a powerful tool to explore unconscious thoughts and suppressed emotions.”
“Anecdotally, Datura has been described as a ‘neurochemical reset’ by some, helping to temporarily wipe the slate clean of habitual mental patterns, including social anxiety and inhibition.”
@Proex who helped make this thread has taken datura a week ago in this thread:

My Datura microdose Experience [BOTB]
FOR PEOPLE WHO DON'T KNOW WHAT THE PLANT IS: https://psychonautwiki.org/wiki/Datura so the story starts when i found some seeds in my grandma's garden the other day https://looksmax.org/threads/i-found-datura-in-my-grandmas-yard.1536911/ but you niggas know @Proex is smart :bigbrain: and...
His trip report:
For his trip he only used 20 seeds, even tho it's a small amount he says it helped him dramatically,
He took the seeds at 3am by soaking them in water and then drinking it.
1h latter he started spewing nonsense to me in this thread:
https://looksmax.org/threads/alrmo-i-hope-you-took-the-fogs.1542022/
He then left the forum cause he was feeling scared at 5am and experienced first signs of delirium
His mouth was dry, he constantly went to the toilet and his heart was pounding at first but then he could barely walk and he started seeing imaginary mosquitos.
He reported smoking an imaginary cig
And then a shadow of @MoggerGaston that looks like the pic bellow
Then he went to bed and had crazy dreams.
The shit is no joke,
but after this he reported very low inhib,
he could finally talk to foids on the street and was outside much more often,
it's like this trip made him an extrovert, this is the best drug since test tbh.
@Proex @Mainlander @Copercel