huracaan
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This guide was written by hand ON MOBILE. This is a no BS guide on DNP written by someone who has done DNP and has hours upon hours of research on the chemical.
As I’m writing this I see another thread that already has all of this info I’m already too far in to give up
Brief History:
Dinitrophenol is a chemical that was popularized during WW2 for its usages in making bombs. It’s a very potent and flammable chemical which explodes under heat.
Dinitrophenol (DNP) became a weight loss drug when put into capsules due to its affects on the factory line workers reporting extremely high internal body temperatures and weight loss when handling the chemical. Companies capitalized on this and turned it into a pill and sold it to the public. If you have heard of DNP before, you may have heard that it’s “deadly” which stems from idiots taking an extremely high dosage in hopes of losing more weight because “muhhh bigger is better”
DNP is now classified as a poison by every government agency in the USA and UK, this is because of people misusing it and overdosing.
How does it work?
A more scientific study done here, which I will be pulling info from : https://www.sciencedirect.com/topics/neuroscience/2-4-dinitrophenol
Essentially, DNP uncouples parts of the mitochondria in the affected environment which RAISES YOUR METABOLIC RATE. This drug quite literally makes your metabolism faster, now you can stop wishing you had a faster metabolism.
It does some shit with your thyroid, so if you have a pre-existing thyroid issue, do more research or simply do not take it, it’s not worth your life. (It interacts with T4)
Safety and Precautions:
DNP is a very safe compound to use, as long as you aren’t taking more than 300mg daily.
The only reported deaths on DNP have been from overdoses starting at 1000MG, or people who are prone to getting cataracts, or if you are allergic to it. So realistically, there’s a very low chance of dying if you are SANE.
NOTE: Do not mess with DNP, it’s not a nice compound, if you fuck up and take too much, or do something you should whilst on it, you will die, and there is nothing the paramedics can do. As of December 2024 (now) there is zero cure for a DNP overdose.
The best way to figure out if DNP is safe for you is to purchase antihistamine and anti allergy pills on Amazon which have a good chance of genuinely saving you if you encounter what I’m going to talk about.
What to look for after taking the pill:
(Around 90% of people are NOT allergic)
Supplements to Take:
I have seen a few posts on here asking about supplements to take, so I’ll be answering that.
Whilst on DNP, you’re going to want to supplement antioxidants because a rare second order metabolite of DNP (a semiquinone) can cause cataracts. Most people (99%-99.9%) are able to neutralize this pro-oxidant without any problems. The other few probably have some deficiency or genetic mutation that makes them susceptible. Antioxidants can be thought of as insurance against this for those unlucky few who are susceptible.
My typical recommendation is simple: a normal daily dose of the commons - vit C, vit E, and if you have them ALA and coQ10. DO NOT SUPERDOSE.
Side Effects:
The most common side effects reported by most users are:
Dehydration, fatigue, diarrhea (at a high dose), drowsiness, extreme heat.
Personally, the sides are dose dependent, this meaning that the sides change or worsen based on how high your dose is. At 250mg, I typically just get demotivated, tired, heat. But recently I took 500mg per day and it was NOT worth it, I wasn’t losing much more weight than I was on 250mg, and the sides were pure misery. I wasn’t comfortable at any point during the day, my body temperature was so high I would be sitting in front of a fan and be SWEATING (literal beads running down my forehead) and my throat still hurts so bad because of the dehydration, it’s like getting strep throat but 5x worse. Keep in mind I live somewhere COLD (35F usually) and I was that hot. On 500mg I was genuinely depressed, every task was exhausting.
Over time, your body does build up a tolerance to DNP, ever so slightly. This only really happens when doing a long cycle. In 1937 there was a study done by a doctor referred to as Simkins, who studied the effects of DNP on 159 subjects who were kept on DNP for many months to over a year. It's worth noting that he looked at a number of different markers of health, reporting no hepatotoxicity, no renal toxicity, no cardiovascular effects (except for a marked drop in blood pressure in hypertensive patients), no cardiotoxicity, no consistent effect on blood sugar, an improvement in carbohydrate tolerance, negligible effects on the gastro-intestinal tract, and no effect on blood cholesterol.
Your main enemy is going to be HEAT when taking DNP. If you live in a hot state without AC, I wouldn’t take it. The heat on 250mg honestly isn’t terrible, when you first start taking it, you will feel it, but later into your cycle you start to get more comfortable.
Dosing
I’d personally recommend 250MG every day as a dosage. As for “what time should I take it” I personally take my pill at 10PM, this is because DNP is fully in your system 5 hours after you take the pill, so you might as well be sleeping while at your hottest.
There's a great deal of variation in individual response to DNP. While some people can produce a fever with as little as 300mg/day, others can take 600mg/day and still be under 99 degrees. There are a number of different factors involved: people metabolize DNP at different rates, some people are larger than others so that a given dosage is lower relative to their bodyweight, and some people seem better able to radiate heat. All of these factors and more make dosage prescriptions extremely individual with DNP. For this reason, sweeping generalizations for dosing are completely inadequate. Users need to start with a low dosage and slowly increase it until they find the dosage that's right for them, be it 200mg/day or 600mg/day. As a rough, general guideline, though, I'd say 200mg/day is a low dosage, 400mg/day is a moderate dosage, and 600mg/day is a high (dangerous) dosage.
A rule of thumb when choosing a dosage on DNP is to think of 100MG = 10% increase in metabolic rate.
IMPORTANT: HALF LIFE
DNP has a half life of 36 hours meaning it reaches full potency in your system. It takes about 5 days for it to reach its full potency.
Do NOT take another few pills if you don’t feel anything the first day or 2, you will most likely be miserable if you do.
This concludes my guide for now, feel free to ask questions, I’m hesitant to put my all into this thread bc I forgot someone else already made a thread on this.
As I’m writing this I see another thread that already has all of this info I’m already too far in to give up
Brief History:
Dinitrophenol is a chemical that was popularized during WW2 for its usages in making bombs. It’s a very potent and flammable chemical which explodes under heat.
Dinitrophenol (DNP) became a weight loss drug when put into capsules due to its affects on the factory line workers reporting extremely high internal body temperatures and weight loss when handling the chemical. Companies capitalized on this and turned it into a pill and sold it to the public. If you have heard of DNP before, you may have heard that it’s “deadly” which stems from idiots taking an extremely high dosage in hopes of losing more weight because “muhhh bigger is better”
DNP is now classified as a poison by every government agency in the USA and UK, this is because of people misusing it and overdosing.
How does it work?
A more scientific study done here, which I will be pulling info from : https://www.sciencedirect.com/topics/neuroscience/2-4-dinitrophenol
Essentially, DNP uncouples parts of the mitochondria in the affected environment which RAISES YOUR METABOLIC RATE. This drug quite literally makes your metabolism faster, now you can stop wishing you had a faster metabolism.
It does some shit with your thyroid, so if you have a pre-existing thyroid issue, do more research or simply do not take it, it’s not worth your life. (It interacts with T4)
Safety and Precautions:
DNP is a very safe compound to use, as long as you aren’t taking more than 300mg daily.
The only reported deaths on DNP have been from overdoses starting at 1000MG, or people who are prone to getting cataracts, or if you are allergic to it. So realistically, there’s a very low chance of dying if you are SANE.
NOTE: Do not mess with DNP, it’s not a nice compound, if you fuck up and take too much, or do something you should whilst on it, you will die, and there is nothing the paramedics can do. As of December 2024 (now) there is zero cure for a DNP overdose.
The best way to figure out if DNP is safe for you is to purchase antihistamine and anti allergy pills on Amazon which have a good chance of genuinely saving you if you encounter what I’m going to talk about.
What to look for after taking the pill:
- Peripheral Neuropathy
(Around 90% of people are NOT allergic)
Supplements to Take:
I have seen a few posts on here asking about supplements to take, so I’ll be answering that.
Whilst on DNP, you’re going to want to supplement antioxidants because a rare second order metabolite of DNP (a semiquinone) can cause cataracts. Most people (99%-99.9%) are able to neutralize this pro-oxidant without any problems. The other few probably have some deficiency or genetic mutation that makes them susceptible. Antioxidants can be thought of as insurance against this for those unlucky few who are susceptible.
My typical recommendation is simple: a normal daily dose of the commons - vit C, vit E, and if you have them ALA and coQ10. DO NOT SUPERDOSE.
Side Effects:
The most common side effects reported by most users are:
Dehydration, fatigue, diarrhea (at a high dose), drowsiness, extreme heat.
Personally, the sides are dose dependent, this meaning that the sides change or worsen based on how high your dose is. At 250mg, I typically just get demotivated, tired, heat. But recently I took 500mg per day and it was NOT worth it, I wasn’t losing much more weight than I was on 250mg, and the sides were pure misery. I wasn’t comfortable at any point during the day, my body temperature was so high I would be sitting in front of a fan and be SWEATING (literal beads running down my forehead) and my throat still hurts so bad because of the dehydration, it’s like getting strep throat but 5x worse. Keep in mind I live somewhere COLD (35F usually) and I was that hot. On 500mg I was genuinely depressed, every task was exhausting.
Over time, your body does build up a tolerance to DNP, ever so slightly. This only really happens when doing a long cycle. In 1937 there was a study done by a doctor referred to as Simkins, who studied the effects of DNP on 159 subjects who were kept on DNP for many months to over a year. It's worth noting that he looked at a number of different markers of health, reporting no hepatotoxicity, no renal toxicity, no cardiovascular effects (except for a marked drop in blood pressure in hypertensive patients), no cardiotoxicity, no consistent effect on blood sugar, an improvement in carbohydrate tolerance, negligible effects on the gastro-intestinal tract, and no effect on blood cholesterol.
Your main enemy is going to be HEAT when taking DNP. If you live in a hot state without AC, I wouldn’t take it. The heat on 250mg honestly isn’t terrible, when you first start taking it, you will feel it, but later into your cycle you start to get more comfortable.
Dosing
I’d personally recommend 250MG every day as a dosage. As for “what time should I take it” I personally take my pill at 10PM, this is because DNP is fully in your system 5 hours after you take the pill, so you might as well be sleeping while at your hottest.
There's a great deal of variation in individual response to DNP. While some people can produce a fever with as little as 300mg/day, others can take 600mg/day and still be under 99 degrees. There are a number of different factors involved: people metabolize DNP at different rates, some people are larger than others so that a given dosage is lower relative to their bodyweight, and some people seem better able to radiate heat. All of these factors and more make dosage prescriptions extremely individual with DNP. For this reason, sweeping generalizations for dosing are completely inadequate. Users need to start with a low dosage and slowly increase it until they find the dosage that's right for them, be it 200mg/day or 600mg/day. As a rough, general guideline, though, I'd say 200mg/day is a low dosage, 400mg/day is a moderate dosage, and 600mg/day is a high (dangerous) dosage.
A rule of thumb when choosing a dosage on DNP is to think of 100MG = 10% increase in metabolic rate.
IMPORTANT: HALF LIFE
DNP has a half life of 36 hours meaning it reaches full potency in your system. It takes about 5 days for it to reach its full potency.
Do NOT take another few pills if you don’t feel anything the first day or 2, you will most likely be miserable if you do.
This concludes my guide for now, feel free to ask questions, I’m hesitant to put my all into this thread bc I forgot someone else already made a thread on this.