Does isotretinoin close growth plates?

[Void_]

Isotretinoin for severe, persistent acne that hasn't responded to any treatments. 30mg at 16.5 years old, will my plates close prematurely?

 

[Gaygymmaxx]

Yes

 

[Gaygymmaxx]

But first things first, have you tried mewing?

 

[Deleted member 11126]

Isotretinoin for severe, persistent acne that hasn't responded to any treatments. 30mg at 16.5 years old, will my plates close prematurely?

Anecdotal evidence but my friend was 15-16 took it in the middle of growth spurt and stopped growing past 5'6 he also seemed younger for his age for years. I feel like it slowed puberty for him

 

[castelldefels]

Potential Effects of Oral Isotretinoin on Growth Plate and Height

Longitudinal growth and puberty are the result of a complex interaction of genetic, hormonal, nutritional, and environmental factors. Acne vulgaris is a chronic disease of the pilosebaceous unit that affects 85% of adolescents worldwide. Isotretinoin is a synthetic vitamin A derivative drug...

www.mdpi.com

TLDR: Isotretinoin might cause growth impairment by inducing premature fusion of the growth plates, which seems to be associated with younger age, incremental doses, and the duration of the therapy, beyond individual susceptibility.

Yes