Growth Plates re-opening

[RazeX]

THIS IS ALL THEORETICAL

The very first response to any environmental stimuli, is the corresponding gene.

When my growth plates fused, i realized that even if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

For that reason, i decided to investigate, the very first event i bumped into was the

https://www.researchgate.net/publication/305551142_Reporting_two_cases_with_reappearance_of_growth_plate_after_trauma_in_ankle

Now the Medical/Scientific explanation it’s some long boring shit just know that it was labeled as “Subchondral bone resorption”

From there i started to investigate about a monogene (or family) that could reverse the cartilage fusion allowing for new stem cells to go through apoptosis.

What motivated me is the mainstream confirmation that is theoretically possible for a gene capable of reversing the growth plates to be existing.

I could have kept investigating in general until i would have eventually found something, but the numbers of possible gene is astronomical, so i just played by exclusion.

(Unfortunately this doesn’t guarantee the theoretical location to be true)

“If such gene existed we would expect it to be inside the cartilage” that was my first supposition, it turned out to be true

well guess what, we went from billions to several thousands of genes, but it’s still an enormous amount to identify, so i filtered again simply by diving monogenes and polygenes, it turned out that if such gene existed it would most likely be a monogene (I mean it’s pretty fucking obvious considering it’s literally made to give humans the ability to reverse Plates fusion)

As I said, doesn’t give us a guarantee, but it’s a rational guessing.

Now let just keep filtering, how many monogenes inside the cartilage exists?

There’s not an identified number even tho the governative unknome should know, but it’s up to 450 genes.

From there i have no clue where to go anymore, so i posted this thread with the solely intention to allow someone who knows better than me (pretty sure in this community there’s tons of people) to be inspired and possibly discover something.

Thanks for reading

 

[JohanBigBalle]

if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

LOOL

 

[Vireon]

 

[Etson]

THIS IS ALL THEORETICAL

The very first response to any environmental stimuli, is the corresponding gene.

When my growth plates fused, i realized that even if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

For that reason, i decided to investigate, the very first event i bumped into was the

https://www.researchgate.net/publication/305551142_Reporting_two_cases_with_reappearance_of_growth_plate_after_trauma_in_ankle

Now the Medical/Scientific explanation it’s some long boring shit just know that it was labeled as “Subchondral bone resorption”

From there i started to investigate about a monogene (or family) that could reverse the cartilage fusion allowing for new stem cells to go through apoptosis.

What motivated me is the mainstream confirmation that is theoretically possible for a gene capable of reversing the growth plates to be existing.

View attachment 4837111

I could have kept investigating in general until i would have eventually found something, but the numbers of possible gene is astronomical, so i just played by exclusion.

(Unfortunately this doesn’t guarantee the theoretical location to be true)

“If such gene existed we would expect it to be inside the cartilage” that was my first supposition, it turned out to be true

View attachment 4837119

well guess what, we went from billions to several thousands of genes, but it’s still an enormous amount to identify, so i filtered again simply by diving monogenes and polygenes, it turned out that if such gene existed it would most likely be a monogene (I mean it’s pretty fucking obvious considering it’s literally made to give humans the ability to reverse Plates fusion)

View attachment 4837127

As I said, doesn’t give us a guarantee, but it’s a rational guessing.

Now let just keep filtering, how many monogenes inside the cartilage exists?

There’s not an identified number even tho the governative unknome should know, but it’s up to 450 genes.

From there i have no clue where to go anymore, so i posted this thread with the solely intention to allow someone who knows better than me (pretty sure in this community there’s tons of people) to be inspired and possibly discover something.

Thanks for reading

 

[masseter.chief]

This is a really interesting theory, I’m very invested in trying to find a way to reopen my growth plates, for now I’m just height frauding with Rick Owens boots to reach 6’1

 

[2s2f]

whatever helps you cope

 

[RazeX]

This is a really interesting theory, I’m very invested in trying to find a way to reopen my growth plates, for now I’m just height frauding with Rick Owens boots to reach 6’1

I forgot to mention PGDH15 is suspected to be correlated to the reversing gene and has potential to reverse age

 

[RazeX]

whatever helps you cope

Be mature for once and if you believe it’s a incorrect theory explain your point rather than insult people

 

[iwannascendpls]

buy 450 mice and activate an individual gene on each

 

[RazeX]

buy 450 mice and activate an individual gene on each

LOL I can’t even say it’s wrong as an idea, lowkey this is giving me ideas

 

[exsttttt]

THIS IS ALL THEORETICAL

The very first response to any environmental stimuli, is the corresponding gene.

When my growth plates fused, i realized that even if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

For that reason, i decided to investigate, the very first event i bumped into was the

https://www.researchgate.net/publication/305551142_Reporting_two_cases_with_reappearance_of_growth_plate_after_trauma_in_ankle

Now the Medical/Scientific explanation it’s some long boring shit just know that it was labeled as “Subchondral bone resorption”

From there i started to investigate about a monogene (or family) that could reverse the cartilage fusion allowing for new stem cells to go through apoptosis.

What motivated me is the mainstream confirmation that is theoretically possible for a gene capable of reversing the growth plates to be existing.

View attachment 4837111

I could have kept investigating in general until i would have eventually found something, but the numbers of possible gene is astronomical, so i just played by exclusion.

(Unfortunately this doesn’t guarantee the theoretical location to be true)

“If such gene existed we would expect it to be inside the cartilage” that was my first supposition, it turned out to be true

View attachment 4837119

well guess what, we went from billions to several thousands of genes, but it’s still an enormous amount to identify, so i filtered again simply by diving monogenes and polygenes, it turned out that if such gene existed it would most likely be a monogene (I mean it’s pretty fucking obvious considering it’s literally made to give humans the ability to reverse Plates fusion)

View attachment 4837127

As I said, doesn’t give us a guarantee, but it’s a rational guessing.

Now let just keep filtering, how many monogenes inside the cartilage exists?

There’s not an identified number even tho the governative unknome should know, but it’s up to 450 genes.

From there i have no clue where to go anymore, so i posted this thread with the solely intention to allow someone who knows better than me (pretty sure in this community there’s tons of people) to be inspired and possibly discover something.

Thanks for reading

maybe if you dissolve the bone in the epiphyseal scar and put a scaffold filled with growth factors with perfect autonomous regulation it could be possible, but no gene is gonna dissolve the bone where the gp was, induce mesenchymal stem cell condensation, and restart longitudinal growth.

 

[exsttttt]

buy 450 mice and activate an individual gene on each

mice dont fuse

 

[Femboy_slayer69420]

copium lol

 

[iwannascendpls]

mice dont fuse

i was joking but I also didn't knew they didn't fuse so I guess ill just kms

 

[vi24v_]

Im sorry but ur interpreting the studies wrong and they don’t mean shit. The study shows damaged bone mimicking cartilage structure not new functional growth plates. The patients in the study did not restart height growth. Growth plates are also controlled by many different systems like PTHrP, estrogen, fgrfr3, IHH etc so there is no singular mechanism that can reverse growth plate fusion lets be realistic. So the statment “a monogene that reverses growth plate fusion” is wrong. - there’s lots of other stuff that’s wrong but I’m too tired to go into it. It was a good theory tho

 

[vi24v_]

I forgot to mention PGDH15 is suspected to be correlated to the reversing gene and has potential to reverse age

U mean 15-PGDH - it works by breaking down PGE2 so when it’s inhibited it can improve healing in tissues (including bone marrow) but that’s bcz the stem cells are still intact, after a plate fuses it replaces stem cells and cartilage with bone which can’t be rebuilt into a growth plate. This is not true and just speculation with no evidence and is not even a theory that could make sense

 

[RazeX]

maybe if you dissolve the bone in the epiphyseal scar and put a scaffold filled with growth factors with perfect autonomous regulation it could be possible, but no gene is gonna dissolve the bone where the gp was, induce mesenchymal stem cell condensation, and restart longitudinal growth.

I totally agree only if the entire idea wasn’t the gene to be able to do all of it by itslef

 

[RazeX]

Im sorry but ur interpreting the studies wrong and they don’t mean shit. The study shows damaged bone mimicking cartilage structure not new functional growth plates. The patients in the study did not restart height growth. Growth plates are also controlled by many different systems like PTHrP, estrogen, fgrfr3, IHH etc so there is no singular mechanism that can reverse growth plate fusion lets be realistic. So the statment “a monogene that reverses growth plate fusion” is wrong. - there’s lots of other stuff that’s wrong but I’m too tired to go into it. It was a good theory tho

there’s a lot of this I don’t know about, you clearly know more than me, but you missed one key factor, the entire idea was based off the possibility for that gene to exist and as long as it’s backed up by mainstream source (as in photos) I believe there’s at least a connection to what I said, other than that, you’re very informed

 

[RazeX]

U mean 15-PGDH - it works by breaking down PGE2 so when it’s inhibited it can improve healing in tissues (including bone marrow) but that’s bcz the stem cells are still intact, after a plate fuses it replaces stem cells and cartilage with bone which can’t be rebuilt into a growth plate. This is not true and just speculation with no evidence and is not even a theory that could make sense

Absolutely but as I said, the idea behind it was for the possibility that 15 PGDH could have a connection with the theoretical gene I was referring to, so you could call it “biological gambling”

 

[spanishmanlet]

THIS IS ALL THEORETICAL

The very first response to any environmental stimuli, is the corresponding gene.

When my growth plates fused, i realized that even if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

For that reason, i decided to investigate, the very first event i bumped into was the

https://www.researchgate.net/publication/305551142_Reporting_two_cases_with_reappearance_of_growth_plate_after_trauma_in_ankle

Now the Medical/Scientific explanation it’s some long boring shit just know that it was labeled as “Subchondral bone resorption”

From there i started to investigate about a monogene (or family) that could reverse the cartilage fusion allowing for new stem cells to go through apoptosis.

What motivated me is the mainstream confirmation that is theoretically possible for a gene capable of reversing the growth plates to be existing.

View attachment 4837111

I could have kept investigating in general until i would have eventually found something, but the numbers of possible gene is astronomical, so i just played by exclusion.

(Unfortunately this doesn’t guarantee the theoretical location to be true)

“If such gene existed we would expect it to be inside the cartilage” that was my first supposition, it turned out to be true

View attachment 4837119

well guess what, we went from billions to several thousands of genes, but it’s still an enormous amount to identify, so i filtered again simply by diving monogenes and polygenes, it turned out that if such gene existed it would most likely be a monogene (I mean it’s pretty fucking obvious considering it’s literally made to give humans the ability to reverse Plates fusion)

View attachment 4837127

As I said, doesn’t give us a guarantee, but it’s a rational guessing.

Now let just keep filtering, how many monogenes inside the cartilage exists?

There’s not an identified number even tho the governative unknome should know, but it’s up to 450 genes.

From there i have no clue where to go anymore, so i posted this thread with the solely intention to allow someone who knows better than me (pretty sure in this community there’s tons of people) to be inspired and possibly discover something.

Thanks for reading

You should start lab testing ngl. Or the chinese find a solution in 5 years

 

[spanishmanlet]

THIS IS ALL THEORETICAL

The very first response to any environmental stimuli, is the corresponding gene.

When my growth plates fused, i realized that even if there were a method to re-initialize cartilage growth, certainly ”they” wouldn’t allow to know, so if someone like me knew something, probably got kirked.

For that reason, i decided to investigate, the very first event i bumped into was the

https://www.researchgate.net/publication/305551142_Reporting_two_cases_with_reappearance_of_growth_plate_after_trauma_in_ankle

Now the Medical/Scientific explanation it’s some long boring shit just know that it was labeled as “Subchondral bone resorption”

From there i started to investigate about a monogene (or family) that could reverse the cartilage fusion allowing for new stem cells to go through apoptosis.

What motivated me is the mainstream confirmation that is theoretically possible for a gene capable of reversing the growth plates to be existing.

View attachment 4837111

I could have kept investigating in general until i would have eventually found something, but the numbers of possible gene is astronomical, so i just played by exclusion.

(Unfortunately this doesn’t guarantee the theoretical location to be true)

“If such gene existed we would expect it to be inside the cartilage” that was my first supposition, it turned out to be true

View attachment 4837119

well guess what, we went from billions to several thousands of genes, but it’s still an enormous amount to identify, so i filtered again simply by diving monogenes and polygenes, it turned out that if such gene existed it would most likely be a monogene (I mean it’s pretty fucking obvious considering it’s literally made to give humans the ability to reverse Plates fusion)

View attachment 4837127

As I said, doesn’t give us a guarantee, but it’s a rational guessing.

Now let just keep filtering, how many monogenes inside the cartilage exists?

There’s not an identified number even tho the governative unknome should know, but it’s up to 450 genes.

From there i have no clue where to go anymore, so i posted this thread with the solely intention to allow someone who knows better than me (pretty sure in this community there’s tons of people) to be inspired and possibly discover something.

Thanks for reading

You should start lab testing ngl. Or the chinese find a solution in 5 years

 

[BP.KOON]

Yeah bro lets just wait until 2050 and we 50y when we do this