20/04/2008
Master
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Tell me youve never used accutane without telling me youve never used accutane niggaKill yourself instead of taking accutane theory
I still take accutane after 3 years + DnrdTell me youve never used accutane without telling me youve never used accutane nigga
Short term Accutane sides :
Your skin get worse the first week and make it bloated and if you have scars it hurt like a mf
You became weak to sunlight like a fucking vampire
Can make you bleed and can literraly cut your lips like Mpmd
And after a month it can even have effects on your mood like their dermatologist claiming that their patients won’t to kill themselves after accutane
And for long term go see babies skull who took accutane sooo…. Accutane is a no
Short term sides of megaflsing panthonoic acid
None
Long term
Toxicity
If accutane was that safe skin care company would be bankrupt and accutane would be available to the mass and would be like top 5 medicines ever created
Nigga you microdosed it or else you some sort of generic freak who can handle all the sidesI still take accutane after 3 years + Dnrd
There's no fucking side effects dumbass just get a good dermatologist and at most your skin and hair becomes dryNigga you microdosed it or else you some sort of generic freak who can handle all the sides
How mush you usedThere's no fucking side effects dumbass just get a good dermatologist and at most your skin and hair becomes dry
There's no fucking side effects dumbass just get a good dermatologist and at most your skin and hair becomes dry
It Improved because your hair is oily, i took 40mg daily for my acne treatment and now i take 20mg daily to maintain glass skinHow mush you used
+you fucking lier i tried accutane in the past and my hair actually improved what are you larpibg about
With medical follow-up thoIt Improved because your hair is oily, i took 40mg daily for my acne treatment and now i take 20mg daily to maintain glass skin
nigga thats baby dose i knew you micro dose itIt Improved because your hair is oily, i took 40mg daily for my acne treatment and now i take 20mg daily to maintain glass skin
It's not retard, you don't need more than 40mg, just need to take it for at least 1 year straightnigga thats baby dose i knew you micro dose it
Nigga the lowest people take is like 0.5 mg/kg it can go up to 2mg/kg for them to use 40 mg they have to be femboys like tf how did you see any results im sure your either lying or skinny as hell or your a fucking femboy or somth cause that doesn’t make senseIt's not retard, you don't need more than 40mg, just need to take it for at least 1 year straight
40mg+ isn't even legal in 99,99% of countries nigger, i'm actually concerned that you might have mental problemsNigga the lowest people take is like 0.5 mg/kg it can go up to 2mg/kg for them to use 40 mg they have to be femboys like tf how did you see any results im sure your either lying or skinny as hell or your a fucking femboy or somth cause that doesn’t make sense
Wtf are you on like the lowest accutane dose is 40 mg tablets their arent 20 mg40mg+ isn't even legal in 99,99% of countries nigger, i'm actually concerned that you might have mental problems
40mg+ isn't even legal in 99,99% of countries nigger, i'm actually concerned that you might have mental problems
Imma busy man and seriously is it all you can reply me with “why are you replying me 4 weekz later muhh muhh” cause i dont fucking rot in org like you you literally responded to me in literally like 2-5 min you descholarized jobbless fagotNigga why are you replying after 4 weeks shut yo ass up
Sub 90 iq faggot40mg+ isn't even legal in 99,99% of countries nigger, i'm actually concerned that you might have mental problems (traduction : i just larp saying whatever tf just to sound smart )
JoinedJun 17, 2024Posts634Imma busy man and seriously is it all you can reply me with “why are you replying me 4 weekz later muhh muhh” cause i dont fucking rot in org like you you literally responded to me in literally like 2-5 min you descholarized jobbless fagot
Arent you the zetsy guy who said hell gladly suck david cock ?JoinedJun 17, 2024Posts634
Yes thats me i would suck his cockArent you the zetsy guy who said hell gladly suck david cock ?
Yes thats me i would suck his cock
Ur subhuman and mixed you don't deverse it niggerThen sock my cock you gay faggot
Nigga i never posted my faceUr subhuman and mixed you don't deverse it nigger
@ClavicularTitle
@Clavicular what was your experience with it ?@Clavicular
fucking retarded cretin you can get results with 5mg a fucking week you retarded nigger that is an acutal microdosenigga thats baby dose i knew you micro dose it
Nigga i swear i know some bodybuilders who use 150 mg accutanefucking retarded cretin you can get results with 5mg a fucking week you retarded nigger that is an acutal microdose
40mg is literally very high unless you go with outdated science from 20th century then go ahead you retarded nigger
yes nigger maybe because they are retarded + use fucking 10 kilos of tren havent you given that a thoughtNigga i swear i know some bodybuilders who use 150 mg accutane
Aren’t you the guy who recommended people to use accutane and finasteride while they aren’t even on gear do you know the impact it can have on someone personallity like nigga they would get fucking anhedonia at this pointyes nigger maybe because they are retarded + use fucking 10 kilos of tren havent you given that a thought
yes anhedonia and severe depression and 0 t they would also transition and have permament brain damage with 0 dopamineAren’t you the guy who recommended people to use accutane and finasteride while they aren’t even on gear do you the impact it can have on someone personallity like nigga they would get fucking anhedonia at this point
Tf are you talking aboutyes anhedonia and severe depression and 0 t they would also transition and have permament brain damage with 0 dopamine
side effects of accutane and dht blockers. brutal stuff manTf are you talking about
also they are very well documented with very high quality clinical trialsyes anhedonia and severe depression and 0 t they would also transition and have permament brain damage with 0 dopamine
Nigga no go read some research about finasteride post syndromeside effects of accutane and dht blockers. brutal stuff man
yea man thats very good research with science backing it up a nigga cant denyNigga no go read some research about finasteride post syndrome
And anecdotes of accutane users or dermatologists
what is nigger even waffling manNigga no one should take you ass seriously im sure you have some mental problems
Like nigga why tf do you like hitler that mush to call him a legend
you said if hitler was born 400 years ago he would be a legendyea man thats very good research with science backing it up a nigga cant deny
and also here are my sources for dhtwhat is nigger even waffling man
you could refer to the fact i use the word nigger every sentence but you chose hitler when i literally never even said anything about the nigger
thats trueyou said if hitler was born 400 years ago he would be a legend
nigger what the actual fuck even is thatand also here are my sources for dht
Stoner, E. (1990). The clinical development of a 5α-reductase inhibitor, finasteride. The Journal of steroid biochemistry and molecular biology, 37(3), 375-378. [2] Vuichoud, C., & Loughlin, K. R. (2015). Benign prostatic hyperplasia: epidemiology, economics and evaluation. Can J Urol, 22(Suppl 1), 1-6. [3] Adil, A., & Godwin, M. (2017). The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis. Journal of the American Academy of Dermatology, 77(1), 136-141. [4] Schumacher, M., Hussain, R., Gago, N., Oudinet, J. P., Mattern, C., & Ghoumari, A. (2012). Progesterone synthesis in the nervous system: implications for myelination and myelin repair. Frontiers in neuroscience, 6, 10. [5] Skeldon, S. C., Macdonald, E. M., Law, M. R., Huang, A., Paterson, J. M., Mamdani, M. M., & Juurlink, D. (2017). The cardiovascular safety of dutasteride. The Journal of urology, 197(5), 1309-1314. [6] Lee, H. J., & Chang, C. (2003). Recent advances in androgen receptor action. Cellular and Molecular Life Sciences CMLS, 60(8), 1613-1622. [7] Bolton, E. C., So, A. Y., Chaivorapol, C., Haqq, C. M., Li, H., & Yamamoto, K. R. (2007). Cell-and gene-specific regulation of primary target genes by the androgen receptor. Genes & development, 21(16), 2005-2017. [8] Winiarska, A., Mandt, N., Kamp, H., Hossini, A., Seltmann, H., Zouboulis, C. C., & Blume-Peytavi, U. (2006). Effect of 5α-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells. Skin pharmacology and physiology, 19(6), 311-321. [9] Chhipa, R. R., Halim, D., Cheng, J., Zhang, H. Y., Mohler, J. L., Ip, C., & Wu, Y. (2013). The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific. The Prostate, 73(14), 1483-1494. [10] Mella, J. M., Perret, M. C., Manzotti, M., Catalano, H. N., & Guyatt, G. (2010). Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review. Archives of dermatology, 146(10), 1141-1150. [11] Di Loreto, C., La Marra, F., Mazzon, G., Belgrano, E., Trombetta, C., & Cauci, S. (2014). Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. PLoS One, 9(6). [12] Overstreet, J. W., Fuh, V. L., Gould, J., Howards, S. S., Lieber, M. M., Hellstrom, W., ... & LEWIS, R. (1999). Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men. The Journal of urology, 162(4), 1295-1300. [13] Samplaski, M. K., Lo, K., Grober, E., & Jarvi, K. (2013). Finasteride use in the male infertility population: effects on semen and hormone parameters. Fertility and sterility, 100(6), 1542-1546. [14] Amory, J. K., Wang, C., Swerdloff, R. S., Anawalt, B. D., Matsumoto, A. M., Bremner, W. J., ... & Clark, R. V. (2007). The effect of 5α-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men. The Journal of Clinical Endocrinology & Metabolism, 92(5), 1659-1665. [15] Traish, A. M. (2020). Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm. The World Journal of Men's Health, 38. [16] Traish, A., Haider, K. S., Doros, G., & Haider, A. (2017). Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction. Hormone molecular biology and clinical investigation, 30(3). [17] Doulabi, S. R. S. M., Kavoussi, H., Isapour, D., Hashemian, A., & Taheriniya, A. (2013). Effect of finasteride on lipid profile in individuals with androgenetic alopecia. African Journal of Pharmacy and Pharmacology, 7(6), 315-317. [18] Duskova, M., Hill, M., & Starka, L. (2010). Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride. Endocr Regul, 44(1), 3-8. [19] Gild, P., Cole, A. P., Krasnova, A., Dickerman, B. A., von Landenberg, N., Sun, M., ... & Kibel, A. S. (2018). Liver disease in men undergoing androgen deprivation therapy for prostate cancer. The Journal of urology, 200(3), 573-581. [20] Mendenhall, C. L. (1968). Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis. The American journal of digestive diseases, 13(9), 783-791. [21] Jacqueson, A., Thevenin, M., Warnet, J. M., Claude, J. R., & Truhaut, R. (1978). Comparative Study of the Protective Effect of an Anabolic Steroid. In Toxicological Aspects of Food Safety (pp. 193-196). Springer, Berlin, Heidelberg. [22] Kelly, D. M., Nettleship, J. E., Akhtar, S., Muraleedharan, V., Sellers, D. J., Brooke, J. C., ... & Jones, T. H. (2014). Testosterone suppresses the expression of regulatory enzymes of fatty acid synthesis and protects against hepatic steatosis in cholesterol-fed androgen deficient mice. Life sciences, 109(2), 95-103. [23] Lin, H. Y., Yu, I. C., Wang, R. S., Chen, Y. T., Liu, N. C., Altuwaijri, S., ... & Yeh, S. (2008). Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology, 47(6), 1924-1935. [24] Völzke, H., Aumann, N., Krebs, A., Nauck, M., Steveling, A., Lerch, M. M., ... & Wallaschofski, H. (2010). Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men. International journal of andrology, 33(1), 45-53. [25] Velazquez, I., & Alter, B. P. (2004). Androgens and liver tumors: Fanconi's anemia and non‐Fanconi's conditions. American journal of hematology, 77(3), 257-267. [26] Di Loreto, C., La Marra, F., Mazzon, G., Belgrano, E., Trombetta, C., & Cauci, S. (2014). Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. PLoS One, 9(6). [27] Hsieh, J. T., Chen, S. C., Yu, H. J., & Chang, H. C. (2011). Finasteride upregulates expression of androgen receptor in hyperplastic prostate and LNCaP cells: implications for chemoprevention of prostate cancer. The Prostate, 71(10), 1115-1121. [28] Pinsky, M. R., Gur, S., Tracey, A. J., Harbin, A., & Hellstrom, W. J. (2011). The effects of chronic 5‐alpha‐reductase inhibitor (dutasteride) treatment on rat erectile function. The journal of sexual medicine, 8(11), 3066-3074. [29] Iacono, F., Prezioso, D., Ruffo, A., Illiano, E., Romis, L., Di Lauro, G., ... & Amato, B. (2012). Testosterone deficiency causes penile fibrosis and organic erectile dysfunction in aging men. Evaluating association among Age. BMC surgery, 12(S1), S24. [30] Zhang, M. G., Wang, X. J., Shen, Z. J., & Gao, P. J. (2013). Long-term oral administration of 5α-reductase inhibitor attenuates erectile function by inhibiting autophagy and promoting apoptosis of smooth muscle cells in corpus cavernosum of aged rats. Urology, 82(3), 743-e9. [31] Melcangi, R. C., Caruso, D., Abbiati, F., Giatti, S., Calabrese, D., Piazza, F., & Cavaletti, G. (2013). Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post‐finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. The journal of sexual medicine, 10(10), 2598-2603. [32] Alanazi, N. (2016). Assessing the quality of life and health outcomes of Androgenic Alopecia patients using Propecia (Doctoral dissertation, Rutgers University-School of Health Related Professions). [33] Melcangi, R. C., Caruso, D., Abbiati, F., Giatti, S., Calabrese, D., Piazza, F., & Cavaletti, G. (2013). Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post‐finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. The journal of sexual medicine, 10(10), 2598-2603. [34] Caruso, D., Abbiati, F., Giatti, S., Romano, S., Fusco, L., Cavaletti, G., & Melcangi, R. C. (2015). Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma. The Journal of steroid biochemistry and molecular biology, 146, 74-79. [35] Melcangi, R. C., Santi, D., Spezzano, R., Grimoldi, M., Tabacchi, T., Fusco, M. L., ... & Simoni, M. (2017). Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. The Journal of steroid biochemistry and molecular biology, 171, 229-235. [36] Martinez, P. E., Rubinow, D. R., Nieman, L. K., Koziol, D. E., Morrow, A. L., Schiller, C. E., ... & Schmidt, P. J. (2016). 5α-reductase inhibition prevents the luteal phase increase in plasma allopregnanolone levels and mitigates symptoms in women with premenstrual dysphoric disorder. Neuropsychopharmacology, 41(4), 1093. [37] Basaria, S., Jasuja, R., Huang, G., Wharton, W., Pan, H., Pencina, K., ... & Labrie, F. (2016). Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. The Journal of Clinical Endocrinology & Metabolism, 101(12), 4669-4680. [38] Van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002). Functional neurogenesis in the adult hippocampus. Nature, 415(6875), 1030-1034. [39] Stockmeier, C. A., Mahajan, G. J., Konick, L. C., Overholser, J. C., Jurjus, G. J., Meltzer, H. Y., ... & Rajkowska, G. (2004). Cellular changes in the postmortem hippocampus in major depression. Biological psychiatry, 56(9), 640-650. [40] Jacobs, B. L., Van Praag, H., & Gage, F. H. (2000). Adult brain neurogenesis and psychiatry: a novel theory of depression. Molecular psychiatry, 5(3), 262-269. [41] Römer, B., Pfeiffer, N., Lewicka, S., Ben-Abdallah, N., Vogt, M. A., Deuschle, M., ... & Gass, P. (2010). Finasteride treatment inhibits adult hippocampal neurogenesis in male mice. Pharmacopsychiatry, 43(05), 174-178. [42] Samuels, B. A., & Hen, R. (2011). Neurogenesis and affective disorders. European Journal of Neuroscience, 33(6), 1152-1159. [43] Romeo, E., Ströhle, A., Spalletta, G., Michele, F. D., Hermann, B., Holsboer, F., ... & Rupprecht, R. (1998). Effects of antidepressant treatment on neuroactive steroids in major depression. American Journal of Psychiatry, 155(7), 910-913. [44] Uzunova, V., Sampson, L., & Uzunov, D. P. (2006). Relevance of endogenous 3α-reduced neurosteroids to depression and antidepressant action. Psychopharmacology, 186(3), 351-361. [45] Uzunova, V., Sheline, Y., Davis, J. M., Rasmusson, A., Uzunov, D. P., Costa, E., & Guidotti, A. (1998). Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proceedings of the National Academy of Sciences, 95(6), 3239-3244. [46] Schüle, C., Nothdurfter, C., & Rupprecht, R. (2014). The role of allopregnanolone in depression and anxiety. Progress in neurobiology, 113, 79-87. [47] Rasmusson, A. M., Pinna, G., Paliwal, P., Weisman, D., Gottschalk, C., Charney, D., ... & Guidotti, A. (2006). Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biological psychiatry, 60(7), 704-713. [48] Hellgren, C., Åkerud, H., Skalkidou, A., Bäckström, T., & Sundström-Poromaa, I. (2014). Low serum allopregnanolone is associated with symptoms of depression in late pregnancy. Neuropsychobiology, 69(3), 147-153. [49] Schüle, C., Nothdurfter, C., & Rupprecht, R. (2014). The role of allopregnanolone in depression and anxiety. Progress in neurobiology, 113, 79-87. [50] Murphy, B. P., Abbott, F. V., Allison, C. M., Watts, C., & Ghadirian, A. M. (2004). Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome. Psychoneuroendocrinology, 29(2), 245-268. [51] Uzunova, V., Sheline, Y., Davis, J. M., Rasmusson, A., Uzunov, D. P., Costa, E., & Guidotti, A. (1998). Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proceedings of the National Academy of Sciences, 95(6), 3239-3244. [52] Romeo, E., Ströhle, A., Spalletta, G., Michele, F. D., Hermann, B., Holsboer, F., ... & Rupprecht, R. (1998). Effects of antidepressant treatment on neuroactive steroids in major depression. American Journal of Psychiatry, 155(7), 910-913. [53] Li, L., Kang, Y. X., Ji, X. M., Li, Y. K., Li, S. C., Zhang, X. J., ... & Shi, G. M. (2018). Finasteride inhibited brain dopaminergic system and open‐field behaviors in adolescent male rats. CNS neuroscience & therapeutics, 24(2), 115-125. [54] Litim, N., Bourque, M., Al Sweidi, S., Morissette, M., & Di Paolo, T. (2015). The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson's disease. Neuropharmacology, 97, 86-94. [55] Dazzi, L., Serra, M., Seu, E., Cherchi, G., Pisu, M. G., Purdy, R. H., & Biggio, G. (2002). Progesterone enhances ethanol‐induced modulation of mesocortical dopamine neurons: antagonism by finasterid
so please get the fuck out of my thread you subhuman 45 iq subhuman
nigger if you want to have a scientific discussion send one or 2 sources you believe best support your claim then ill maybe read ityou said if hitler was born 400 years ago he would be a legend
and also here are my sources for dht
Stoner, E. (1990). The clinical development of a 5α-reductase inhibitor, finasteride. The Journal of steroid biochemistry and molecular biology, 37(3), 375-378. [2] Vuichoud, C., & Loughlin, K. R. (2015). Benign prostatic hyperplasia: epidemiology, economics and evaluation. Can J Urol, 22(Suppl 1), 1-6. [3] Adil, A., & Godwin, M. (2017). The effectiveness of treatments for androgenetic alopecia: a systematic review and meta-analysis. Journal of the American Academy of Dermatology, 77(1), 136-141. [4] Schumacher, M., Hussain, R., Gago, N., Oudinet, J. P., Mattern, C., & Ghoumari, A. (2012). Progesterone synthesis in the nervous system: implications for myelination and myelin repair. Frontiers in neuroscience, 6, 10. [5] Skeldon, S. C., Macdonald, E. M., Law, M. R., Huang, A., Paterson, J. M., Mamdani, M. M., & Juurlink, D. (2017). The cardiovascular safety of dutasteride. The Journal of urology, 197(5), 1309-1314. [6] Lee, H. J., & Chang, C. (2003). Recent advances in androgen receptor action. Cellular and Molecular Life Sciences CMLS, 60(8), 1613-1622. [7] Bolton, E. C., So, A. Y., Chaivorapol, C., Haqq, C. M., Li, H., & Yamamoto, K. R. (2007). Cell-and gene-specific regulation of primary target genes by the androgen receptor. Genes & development, 21(16), 2005-2017. [8] Winiarska, A., Mandt, N., Kamp, H., Hossini, A., Seltmann, H., Zouboulis, C. C., & Blume-Peytavi, U. (2006). Effect of 5α-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells. Skin pharmacology and physiology, 19(6), 311-321. [9] Chhipa, R. R., Halim, D., Cheng, J., Zhang, H. Y., Mohler, J. L., Ip, C., & Wu, Y. (2013). The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific. The Prostate, 73(14), 1483-1494. [10] Mella, J. M., Perret, M. C., Manzotti, M., Catalano, H. N., & Guyatt, G. (2010). Efficacy and safety of finasteride therapy for androgenetic alopecia: a systematic review. Archives of dermatology, 146(10), 1141-1150. [11] Di Loreto, C., La Marra, F., Mazzon, G., Belgrano, E., Trombetta, C., & Cauci, S. (2014). Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. PLoS One, 9(6). [12] Overstreet, J. W., Fuh, V. L., Gould, J., Howards, S. S., Lieber, M. M., Hellstrom, W., ... & LEWIS, R. (1999). Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men. The Journal of urology, 162(4), 1295-1300. [13] Samplaski, M. K., Lo, K., Grober, E., & Jarvi, K. (2013). Finasteride use in the male infertility population: effects on semen and hormone parameters. Fertility and sterility, 100(6), 1542-1546. [14] Amory, J. K., Wang, C., Swerdloff, R. S., Anawalt, B. D., Matsumoto, A. M., Bremner, W. J., ... & Clark, R. V. (2007). The effect of 5α-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men. The Journal of Clinical Endocrinology & Metabolism, 92(5), 1659-1665. [15] Traish, A. M. (2020). Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm. The World Journal of Men's Health, 38. [16] Traish, A., Haider, K. S., Doros, G., & Haider, A. (2017). Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction. Hormone molecular biology and clinical investigation, 30(3). [17] Doulabi, S. R. S. M., Kavoussi, H., Isapour, D., Hashemian, A., & Taheriniya, A. (2013). Effect of finasteride on lipid profile in individuals with androgenetic alopecia. African Journal of Pharmacy and Pharmacology, 7(6), 315-317. [18] Duskova, M., Hill, M., & Starka, L. (2010). Changes of metabolic profile in men treated for androgenetic alopecia with 1 mg finasteride. Endocr Regul, 44(1), 3-8. [19] Gild, P., Cole, A. P., Krasnova, A., Dickerman, B. A., von Landenberg, N., Sun, M., ... & Kibel, A. S. (2018). Liver disease in men undergoing androgen deprivation therapy for prostate cancer. The Journal of urology, 200(3), 573-581. [20] Mendenhall, C. L. (1968). Anabolic steroid therapy as an adjunct to diet in alcoholic hepatic steatosis. The American journal of digestive diseases, 13(9), 783-791. [21] Jacqueson, A., Thevenin, M., Warnet, J. M., Claude, J. R., & Truhaut, R. (1978). Comparative Study of the Protective Effect of an Anabolic Steroid. In Toxicological Aspects of Food Safety (pp. 193-196). Springer, Berlin, Heidelberg. [22] Kelly, D. M., Nettleship, J. E., Akhtar, S., Muraleedharan, V., Sellers, D. J., Brooke, J. C., ... & Jones, T. H. (2014). Testosterone suppresses the expression of regulatory enzymes of fatty acid synthesis and protects against hepatic steatosis in cholesterol-fed androgen deficient mice. Life sciences, 109(2), 95-103. [23] Lin, H. Y., Yu, I. C., Wang, R. S., Chen, Y. T., Liu, N. C., Altuwaijri, S., ... & Yeh, S. (2008). Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology, 47(6), 1924-1935. [24] Völzke, H., Aumann, N., Krebs, A., Nauck, M., Steveling, A., Lerch, M. M., ... & Wallaschofski, H. (2010). Hepatic steatosis is associated with low serum testosterone and high serum DHEAS levels in men. International journal of andrology, 33(1), 45-53. [25] Velazquez, I., & Alter, B. P. (2004). Androgens and liver tumors: Fanconi's anemia and non‐Fanconi's conditions. American journal of hematology, 77(3), 257-267. [26] Di Loreto, C., La Marra, F., Mazzon, G., Belgrano, E., Trombetta, C., & Cauci, S. (2014). Immunohistochemical evaluation of androgen receptor and nerve structure density in human prepuce from patients with persistent sexual side effects after finasteride use for androgenetic alopecia. PLoS One, 9(6). [27] Hsieh, J. T., Chen, S. C., Yu, H. J., & Chang, H. C. (2011). Finasteride upregulates expression of androgen receptor in hyperplastic prostate and LNCaP cells: implications for chemoprevention of prostate cancer. The Prostate, 71(10), 1115-1121. [28] Pinsky, M. R., Gur, S., Tracey, A. J., Harbin, A., & Hellstrom, W. J. (2011). The effects of chronic 5‐alpha‐reductase inhibitor (dutasteride) treatment on rat erectile function. The journal of sexual medicine, 8(11), 3066-3074. [29] Iacono, F., Prezioso, D., Ruffo, A., Illiano, E., Romis, L., Di Lauro, G., ... & Amato, B. (2012). Testosterone deficiency causes penile fibrosis and organic erectile dysfunction in aging men. Evaluating association among Age. BMC surgery, 12(S1), S24. [30] Zhang, M. G., Wang, X. J., Shen, Z. J., & Gao, P. J. (2013). Long-term oral administration of 5α-reductase inhibitor attenuates erectile function by inhibiting autophagy and promoting apoptosis of smooth muscle cells in corpus cavernosum of aged rats. Urology, 82(3), 743-e9. [31] Melcangi, R. C., Caruso, D., Abbiati, F., Giatti, S., Calabrese, D., Piazza, F., & Cavaletti, G. (2013). Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post‐finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. The journal of sexual medicine, 10(10), 2598-2603. [32] Alanazi, N. (2016). Assessing the quality of life and health outcomes of Androgenic Alopecia patients using Propecia (Doctoral dissertation, Rutgers University-School of Health Related Professions). [33] Melcangi, R. C., Caruso, D., Abbiati, F., Giatti, S., Calabrese, D., Piazza, F., & Cavaletti, G. (2013). Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post‐finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. The journal of sexual medicine, 10(10), 2598-2603. [34] Caruso, D., Abbiati, F., Giatti, S., Romano, S., Fusco, L., Cavaletti, G., & Melcangi, R. C. (2015). Patients treated for male pattern hair with finasteride show, after discontinuation of the drug, altered levels of neuroactive steroids in cerebrospinal fluid and plasma. The Journal of steroid biochemistry and molecular biology, 146, 74-79. [35] Melcangi, R. C., Santi, D., Spezzano, R., Grimoldi, M., Tabacchi, T., Fusco, M. L., ... & Simoni, M. (2017). Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients. The Journal of steroid biochemistry and molecular biology, 171, 229-235. [36] Martinez, P. E., Rubinow, D. R., Nieman, L. K., Koziol, D. E., Morrow, A. L., Schiller, C. E., ... & Schmidt, P. J. (2016). 5α-reductase inhibition prevents the luteal phase increase in plasma allopregnanolone levels and mitigates symptoms in women with premenstrual dysphoric disorder. Neuropsychopharmacology, 41(4), 1093. [37] Basaria, S., Jasuja, R., Huang, G., Wharton, W., Pan, H., Pencina, K., ... & Labrie, F. (2016). Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. The Journal of Clinical Endocrinology & Metabolism, 101(12), 4669-4680. [38] Van Praag, H., Schinder, A. F., Christie, B. R., Toni, N., Palmer, T. D., & Gage, F. H. (2002). Functional neurogenesis in the adult hippocampus. Nature, 415(6875), 1030-1034. [39] Stockmeier, C. A., Mahajan, G. J., Konick, L. C., Overholser, J. C., Jurjus, G. J., Meltzer, H. Y., ... & Rajkowska, G. (2004). Cellular changes in the postmortem hippocampus in major depression. Biological psychiatry, 56(9), 640-650. [40] Jacobs, B. L., Van Praag, H., & Gage, F. H. (2000). Adult brain neurogenesis and psychiatry: a novel theory of depression. Molecular psychiatry, 5(3), 262-269. [41] Römer, B., Pfeiffer, N., Lewicka, S., Ben-Abdallah, N., Vogt, M. A., Deuschle, M., ... & Gass, P. (2010). Finasteride treatment inhibits adult hippocampal neurogenesis in male mice. Pharmacopsychiatry, 43(05), 174-178. [42] Samuels, B. A., & Hen, R. (2011). Neurogenesis and affective disorders. European Journal of Neuroscience, 33(6), 1152-1159. [43] Romeo, E., Ströhle, A., Spalletta, G., Michele, F. D., Hermann, B., Holsboer, F., ... & Rupprecht, R. (1998). Effects of antidepressant treatment on neuroactive steroids in major depression. American Journal of Psychiatry, 155(7), 910-913. [44] Uzunova, V., Sampson, L., & Uzunov, D. P. (2006). Relevance of endogenous 3α-reduced neurosteroids to depression and antidepressant action. Psychopharmacology, 186(3), 351-361. [45] Uzunova, V., Sheline, Y., Davis, J. M., Rasmusson, A., Uzunov, D. P., Costa, E., & Guidotti, A. (1998). Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proceedings of the National Academy of Sciences, 95(6), 3239-3244. [46] Schüle, C., Nothdurfter, C., & Rupprecht, R. (2014). The role of allopregnanolone in depression and anxiety. Progress in neurobiology, 113, 79-87. [47] Rasmusson, A. M., Pinna, G., Paliwal, P., Weisman, D., Gottschalk, C., Charney, D., ... & Guidotti, A. (2006). Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biological psychiatry, 60(7), 704-713. [48] Hellgren, C., Åkerud, H., Skalkidou, A., Bäckström, T., & Sundström-Poromaa, I. (2014). Low serum allopregnanolone is associated with symptoms of depression in late pregnancy. Neuropsychobiology, 69(3), 147-153. [49] Schüle, C., Nothdurfter, C., & Rupprecht, R. (2014). The role of allopregnanolone in depression and anxiety. Progress in neurobiology, 113, 79-87. [50] Murphy, B. P., Abbott, F. V., Allison, C. M., Watts, C., & Ghadirian, A. M. (2004). Elevated levels of some neuroactive progesterone metabolites, particularly isopregnanolone, in women with chronic fatigue syndrome. Psychoneuroendocrinology, 29(2), 245-268. [51] Uzunova, V., Sheline, Y., Davis, J. M., Rasmusson, A., Uzunov, D. P., Costa, E., & Guidotti, A. (1998). Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine. Proceedings of the National Academy of Sciences, 95(6), 3239-3244. [52] Romeo, E., Ströhle, A., Spalletta, G., Michele, F. D., Hermann, B., Holsboer, F., ... & Rupprecht, R. (1998). Effects of antidepressant treatment on neuroactive steroids in major depression. American Journal of Psychiatry, 155(7), 910-913. [53] Li, L., Kang, Y. X., Ji, X. M., Li, Y. K., Li, S. C., Zhang, X. J., ... & Shi, G. M. (2018). Finasteride inhibited brain dopaminergic system and open‐field behaviors in adolescent male rats. CNS neuroscience & therapeutics, 24(2), 115-125. [54] Litim, N., Bourque, M., Al Sweidi, S., Morissette, M., & Di Paolo, T. (2015). The 5α-reductase inhibitor Dutasteride but not Finasteride protects dopamine neurons in the MPTP mouse model of Parkinson's disease. Neuropharmacology, 97, 86-94. [55] Dazzi, L., Serra, M., Seu, E., Cherchi, G., Pisu, M. G., Purdy, R. H., & Biggio, G. (2002). Progesterone enhances ethanol‐induced modulation of mesocortical dopamine neurons: antagonism by finasterid
so please get the fuck out of my thread you subhuman 45 iq subhuman
niiigga im tired you are right just let me alonenigger if you want to have a scientific discussion send one or 2 sources you believe best support your claim then ill maybe read it
you are delusional if you think anyone is going to sign up on some goofy site and read all that shit
i can probably also list you what is wrong with these studies and why they are shit without even looking at them
hell nah nigger i will keep fucking drilling u wont stop me son of a bitchniiigga im tired you right just let me alone
piece of shit
nigga you just like harrasing people thenhell nah nigger i will keep fucking drilling u wont stop me son of a bitch
love it im just not gonna lie niggernigga you just like harrasing people then
nigger i went through all this fucking bullshit all studies these absolute retards refer to are dogshiti just dont have the enrgy to debate with a wall
soo just write leo longevity finasteride syndrome watch 2 or 3 videos and come back to me
the number one biohacker in hair department is mpmd and even him dont reccomend people to use finasteride and especially the dose you give to people
why tf are you making me work why dont yousend studies to back your claim im a lazy fuck the only reason i sent you those studies is because i enrigistred them in notes in my iphone
Are you talking to talknigger i went through all this fucking bullshit all studies these absolute retards refer to are dogshit
or better yet they dont even refer to studies just make anecdotal claims out of their ass or dont know how dht works because they think exogenous has the same effect on body as endogenous