HeightMaxxing: 3-D printed cartilage and connective tissue

[Deleted member 1973]

https://physicsworld.com/a/handheld-biopen-prints-human-cartilage/

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Handheld biopen prints human cartilage
04 Oct 2018

A handheld “biopen” capable of 3D printing cartilage tissue could for the first time be used during surgery to treat cartilage injuries and osteoarthritus. The extrusion-based device, which prints live stem cells embedded in a hydrogel material, produces constructs that look and behave just like natural articular tissue (Biofabrication 10 045006).

“This is in stark contrast to conventional reparative cartilage made of fibrocartilage, which is very different in structure to physiological cartilage, inferior in quality and not durable,” say the researchers, a multidisciplinary team that includes surgeons, biologists, physicists and engineers. “Our technique and the scaffolds we are able to produce provide much hope for treating patients suffering from cartilage injuries and osteoarthritis.”

While some success has been reported for surgical treatments that exploit engineered cartilage tissue, existing procedures require two separate operations: one to remove the damaged tissue, and another to replace the tissue once it is repaired. What’s more, surgeons report a high failure rate – partly because pre-fabricated scaffolds might not perfectly match the defect, and partly because the implanted tissue is not similar enough to natural cartilage to survive for long inside the body.

Note that this is WITHOUT major attention being paid to the field of cartilage tissue engineering. Furthermore, this article actually serves as a follow-up to this other article:

https://physicsworld.com/a/biopen-speeds-up-stem-cell-repair/

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Biopen speeds up stem-cell repair
20 Mar 2018

As 3D printing technology evolves and advances, we are getting ever closer to the goal of being able to implant 3D printed tissues inside the body. At present, 3D printed cells must first be cultivated and then allowed to grow into viable tissue – which normally takes a few days. But a new instrument, dubbed the biopen, could help to speed up this process. The biopen, developed by researchers in Australia, could allow surgeons to repair damaged bone and cartilage by “drawing” new cells directly onto bone during surgery and then filling in any damaged areas.

I've taken the liberty of bolding and underlining something particularly interesting about these two articles. Notice what it is? The second article, which is about the original release of the Biopen, was published on March 20th of this year, while the first one, which details successful forays into cartilage printing using the Biopen (and even upcoming attempts to surgically implant the tissue) was published this month, roughly 7 months later.

Then there's this:

https://www.sciencedaily.com/releases/2018/10/181010105531.htm

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With today's technology, we can 3-D-print sculptures, mechanical parts, prosthetics, even guns and food. But a team of University of Utah biomedical engineers have developed a method to 3-D-print cells to produce human tissue such as ligaments and tendons, a process that will greatly improve a patient's recovery. A person with a badly damaged ligament, tendon, or ruptured disc could simply have new replacement tissue printed and ultimately implanted in the damaged area, according to a new paper published in the Journal of Tissue Engineering, Part C: Methods.

The paper, for the scientifically-inclined:

https://www.liebertpub.com/doi/10.1089/ten.tec.2018.0184

So it's now possible to 3D print connective tissue such as ligaments and tendons, which are among the soft tissue that is distended and damaged by distraction osteogenesis (ultimately resulting in loss of physical ability). The paper was published on September 14th of this year. This again follows up on the Bi-open article from months before, as well as several other research papers involving printed biological tissue that have been published throughout this year.

And again I repeat that all this progress comes without any special attention paid to the field of tissue engineering. This is a natural progression. So, as I've always said, there's nothing absurd about asserting that a non-crippling, safer, better alternative to distraction osteogenesis could be as close as 10 years away, probably more like 7 or 8 if height increase had as much impetus from the (overwhelmingly male) community of short stature d people who want to be taller as androgenic alopecia gets from men/women who are balding or weight loss procedures get from overweight people.

Stuff like this is the reason why bull sh*t copes like "therapy" and "acceptance" (i.e. resignation) should NEVER be suggested as "solutions" to height dysphoria or any problems involving a person's height. The community ought to be encouraging short people who have experienced height-ism and/or are otherwise unhappy with their height to make as much money as they possibly can so we can all come together and help FUND research like this, so that we can ALL have a solution that doesn't involve excruciating pain and risk of being permanently crippled a la unicorn from this board.

New Scientific Research: 3-D printed cartilage and connective tissue

New Scientific Research: 3-D printed cartilage and connective tissue

www.limblengtheningforum.com

 

[Deleted member 6305]

Lifefuel for manlets

 

[needsolution]

cope for manlets

 

[JustBeCurry]

lifefuel thread thank you

 

[GigaMogger]

I'm 6'2, just here to gloat

 

[W0KESTMOTHF]

Tl dr

 

[needsolution]

I'm 6'2, just here to gloat

no height for face

 

[JizzFarmer]

I'm 6'2, just here to gloat

That's average on this site

So is a 9-inch cock​

 

[Merlix]

Once everyone is 6'2 there is no advantage to being 6'2. Then face will matter even more. Until everyone can have an opry face then money and status will matter more. Its a never ending cycle.

 

[TheEndHasNoEnd]

Once everyone is 6'2 there is no advantage to being 6'2. Then face will matter even more. Until everyone can have an opry face then money and status will matter more. Its a never ending cycle.

That's why you gotta be the first ones to get it

 

[Deleted member 1973]

Extremis is god-tier LLF user

 

[Deleted member 1973]

Surgical uses of 3D printing-centric therapies have a history beginning in the mid-1990s with anatomical modeling for bony reconstructive surgery planning. Patient-matched implants were a natural extension of this work, leading to truly personalized implants that fit one unique individual.[119] Virtual planning of surgery and guidance using 3D printed, personalized instruments have been applied to many areas of surgery including total joint replacement and craniomaxillofacial reconstruction with great success.[120] One example of this is the bioresorbable trachial splint to treat newborns with tracheobronchomalacia[121] developed at the University of Michigan. The use of additive manufacturing for serialized production of orthopedic implants (metals) is also increasing due to the ability to efficiently create porous surface structures that facilitate osseointegration. The hearing aid and dental industries are expected to be the biggest area of future development using the custom 3D printing technology.[122]

In March 2014, surgeons in Swansea used 3D printed parts to rebuild the face of a motorcyclist who had been seriously injured in a road accident.[123] In May 2018, 3D printing has been used for the kidney transplant to save a three-year-old boy.[124] As of 2012, 3D bio-printing technology has been studied by biotechnology firms and academia for possible use in tissue engineering applications in which organs and body parts are built using inkjet printing techniques. In this process, layers of living cells are deposited onto a gel medium or sugar matrix and slowly built up to form three-dimensional structures including vascular systems.[125] Recently, a heart-on-chip has been created which matches properties of cells