N
Not_Sim0o
Iron
- Joined
- Sep 19, 2025
- Posts
- 5
- Reputation
- 6
1. MEWING AND THUMBPULLIMG
Even if many people say they're cope I still want to give them a shot:
-Mewing 24/7(+10 minutes humming experimental)
-Thumbpulling 600 cycles a day per part (10min each)
-Hard chewing 30-60minutes a day
-Orbital pulling (Frontozygomatic suture) same routine as thunbpulling
Thumbpulling works by placing traction on the mid palatal suture, this mechanical tension upregulates DALRD3, which via a tRNA modification (m^3C) enhances translation of ID3 (an inhibitor of DNA binding 3) and thereby boosts osteogenic differentiation of suture stem cells (SuSCs).
Traction causes ECM and Collagen fibers to realign and cause structural mechanosensing, Mesenchymal stem/cell activation and migration toward bone border happens, Up-regulation of Dalrd3 leads to increased IRNA m'C modification which leads to enhanced translation of osteogenic mRNAs (eg., Id3). Osteogenic differentiation of SuSCs/mesenchymal cells causes bone matrix deposition at suture border which causes Sutural growth/adaptation (widening, expansion, shape change)
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC12175324/
pmc.ncbi.nlm.nih.gov
pmc.ncbi.nlm.nih.gov
500+ Anedoctal results and more if counting Mewing only
pmc.ncbi.nlm.nih.gov
Bonesmashing + VIBRATION THERAPY
Nasion:2 minutes x E0D
Chin 5 minutes x E0D
Vibration therapy:10minutes a day(experimental)
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC6877967/
www.nature.com
link.springer.com
pmc.ncbi.nlm.nih.gov
pmc.ncbi.nlm.nih.gov
PHARMACEUTICALS (when I will get money)
Testosterone E300 : 250mg / week
HGH : 6 IU's day
Aromasin : 6.5mg E0D or 12.5 3x / week
Masteron : 150mg/200mg
If I can:
GHK-cu 1mg day
Cebrolysin 20mg
Oral Minoxidil 2.5mg day
Injectable Aminoacids
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC7705876/
pubmed.ncbi.nlm.nih.gov
pmc.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
pubmed.ncbi.nlm.nih.gov
DIET
Animal based diet(Paul Saladino version)
Studies:https://www.cambridge.org/core/jour...olled-trials/6427FFE371BAAC054742E8EBE8147B1D
www.cambridge.org
pubmed.ncbi.nlm.nih.gov
There are clearly more things that I will do,this is just a starting point,I will experiment with Biohacking. I have everything and everyone against me,but I will somehow do it!
Even if many people say they're cope I still want to give them a shot:
-Mewing 24/7(+10 minutes humming experimental)
-Thumbpulling 600 cycles a day per part (10min each)
-Hard chewing 30-60minutes a day
-Orbital pulling (Frontozygomatic suture) same routine as thunbpulling
Thumbpulling works by placing traction on the mid palatal suture, this mechanical tension upregulates DALRD3, which via a tRNA modification (m^3C) enhances translation of ID3 (an inhibitor of DNA binding 3) and thereby boosts osteogenic differentiation of suture stem cells (SuSCs).
Traction causes ECM and Collagen fibers to realign and cause structural mechanosensing, Mesenchymal stem/cell activation and migration toward bone border happens, Up-regulation of Dalrd3 leads to increased IRNA m'C modification which leads to enhanced translation of osteogenic mRNAs (eg., Id3). Osteogenic differentiation of SuSCs/mesenchymal cells causes bone matrix deposition at suture border which causes Sutural growth/adaptation (widening, expansion, shape change)
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC12175324/
Associations of tongue and hyoid position, tongue volume, and pharyngeal airway dimensions with various dentoskeletal growth patterns - PMC
This study investigated the association between tongue and hyoid position, tongue volume, and pharyngeal airway dimensions with craniofacial growth patterns in the sagittal, vertical, and transverse planes. Cone beam computed tomography was used to ...
pmc.ncbi.nlm.nih.gov
Effects of tongue volume reduction on craniofacial growth: A longitudinal study on orofacial skeletons and dental arches - PMC
The interaction between tongue size/volume and craniofacial skeletal growth is essential for understanding the mechanism of specific types of malocclusion and objectively measuring outcomes of various surgical and/or orthodontic treatments. ...
pmc.ncbi.nlm.nih.gov
Correlation between mandibular morphology and masticatory muscle thickness in normal occlusion and mandibular prognathism - PMC
The aim of this study was to evaluate the relationship between masticatory muscle thickness and mandibular morphology in young Korean adults with normal occlusion and mandibular prognathism. Multidetector computed tomography (MDCT) was used to ...
pmc.ncbi.nlm.nih.gov
Bonesmashing + VIBRATION THERAPY
Nasion:2 minutes x E0D
Chin 5 minutes x E0D
Vibration therapy:10minutes a day(experimental)
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC6877967/
Alternated activation with relaxation of periosteum stimulates bone modeling and remodeling - Scientific Reports
Gradual elevation of the periosteum from the original bone surface, based on the principle of distraction osteogenesis, induces endogenous hard and soft tissue formation. This study aimed to assess the impact of alternating protocols of activation with relaxation (periosteal pumping) on bone...
www.nature.com
Subperiosteal new bone formation with the distal tibial classic metaphyseal lesion: prevalence on radiographic skeletal surveys - Pediatric Radiology
Background The classic metaphyseal lesion (CML) is a strong indicator of infant abuse, and the distal tibia is one of the most common sites for this injury. Objective To determine the prevalence of subperiosteal new bone formation accompanying the distal tibial CMLs identified on infant skeletal...
link.springer.com
Surface microcracks signal osteoblasts to regulate alignment and bone formation - PMC
Microcracks are present in bone and can result from fatigue damage due to repeated, cyclically applied stresses. From a mechanical point, microcracks can dissipate strain energy at the advancing tip of a crack to improve overall bone toughness. ...
pmc.ncbi.nlm.nih.gov
Vibration therapy: clinical applications in bone - PMC
The musculoskeletal system is largely regulated through dynamic physical activity and is compromised by cessation of physical loading. There is a need to recreate the anabolic effects of loading on the musculoskeletal system, especially in frail ...
pmc.ncbi.nlm.nih.gov
PHARMACEUTICALS (when I will get money)
Testosterone E300 : 250mg / week
HGH : 6 IU's day
Aromasin : 6.5mg E0D or 12.5 3x / week
Masteron : 150mg/200mg
If I can:
GHK-cu 1mg day
Cebrolysin 20mg
Oral Minoxidil 2.5mg day
Injectable Aminoacids
Studies:https://pmc.ncbi.nlm.nih.gov/articles/PMC7705876/
Testosterone-mediated sex differences in the face shape during adolescence: subjective impressions and objective features - PubMed
Sex identification of a face is essential for social cognition. Still, perceptual cues indicating the sex of a face, and mechanisms underlying their development, remain poorly understood. Previously, our group described objective age- and sex-related differences in faces of healthy male and...
pubmed.ncbi.nlm.nih.gov
Second to fourth digit ratio and face shape - PMC
The average human male face differs from the average female face in size and shape of the jaws, cheek-bones, lips, eyes and nose. It is possible that this dimorphism is determined by sex steroids such as testosterone (T) and oestrogen (E), and ...
pmc.ncbi.nlm.nih.gov
Use of aromatase inhibitors to increase final height - PubMed
During puberty in both sexes, the mechanism involved in epiphyseal fusion is mediated by the action of estrogen through a cascade of events including proliferation, differentiation, and apoptosis of chondrocytes. The enzyme P450 aromatase catalyzes the aromatization of C19 androgens...
pubmed.ncbi.nlm.nih.gov
Aromatase Inhibitors Treatment Alone or With GH Increases Final Height in Short-statured Pubertal Boys-Real-world Data - PubMed
AI treatment extends the growth period, resulting in an AHt surpassing initial predictions. Our findings underscore the potential of AI treatment in midpubertal boys with a short PAHt due to advanced BA and in those treated with GH for ISS.
pubmed.ncbi.nlm.nih.gov
Comparative effects of growth hormone, testosterone, and aromatase inhibitors on height gain in children and adolescents with idiopathic short statures: a network meta-analysis - PubMed
GH, AIs, and combination therapies improve height in children and adolescents with ISS, with letrozole showing a modest advantage but no clear superiority, highlighting the need for individualised treatment.
pubmed.ncbi.nlm.nih.gov
The effect of dihydrotestosterone exposure during or prior to the masculinization programming window on reproductive development in male and female rats - PubMed
Masculinization is programmed by androgen exposure during a masculinization programming window (MPW). Deficiency in MPW androgen action results in reduced size of all reproductive organs and anogenital distance (AGD) and reproductive disorders. Although timing of MPW closing has been defined...
pubmed.ncbi.nlm.nih.gov
Relationship between plasma testosterone and dihydrotestosterone concentrations and male facial hair growth - PubMed
Linear facial hair growth and the density of facial hair were measured by a photographic method and their relationship to plasma testosterone (T) and dihydrotestosterone (DHT) concentrations was examined in twelve healthy men. In addition, we investigated eight men with coeliac disease in whom...
pubmed.ncbi.nlm.nih.gov
Biological effects of androgens and identification of specific dihydrotestosterone-binding sites in cultured human fetal epiphyseal chondrocytes - PubMed
The biological effects of dihydrotestosterone (DHT) and testosterone (T) on cultured human fetal epiphyseal chondrocytes were assessed by studying the ability of these androgens to promote DNA synthesis. DNA synthesis was evaluated by measuring [3H]thymidine incorporation into DNA. After 48-h...
pubmed.ncbi.nlm.nih.gov
1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes - PubMed
Growth plate chondrocytes are affected by 1,25(OH)2D3 and androgens, which may critically interact to regulate proliferation and differentiation during the male pubertal growth spurt. We investigated possible interactions of 1,25(OH)2D3 and the non-aromatizable androgen dihydrotestosterone (DHT)...
pubmed.ncbi.nlm.nih.gov
Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5-alpha reductase type 1 - PubMed
Rat costochondral growth plate chondrocytes exhibit sex-specific and cell maturation dependent responses to testosterone. Only male cells respond to testosterone, although testosterone receptors are present in both male and female cells, suggesting other mechanisms are involved. We examined the...
pubmed.ncbi.nlm.nih.gov
Treatment of delayed male puberty: efficacy of aromatase inhibition - PubMed
We hypothesized that inhibition of estrogen synthesis would delay maturation of the growth plates and ultimately result in increased adult height in boys with delayed puberty. We conducted a randomized, double-blind, placebo-controlled study in which we treated boys with constitutional delay of...
pubmed.ncbi.nlm.nih.gov
Pharmacological management of children with short stature: the role of aromatase inhibitors - PubMed
Among the pharmacological treatments for short stature, aromatase inhibitors are indicated in cases in which bone age advancement may constitute an obstacle for reaching a final height that is in keeping with the family's target height.
pubmed.ncbi.nlm.nih.gov
DIET
Animal based diet(Paul Saladino version)
Studies:https://www.cambridge.org/core/jour...olled-trials/6427FFE371BAAC054742E8EBE8147B1D
Animal products improve child nutrition in Africa
The consumption of milk products, eggs and fish has a positive effect on childhood development in Africa. This has been demonstrated in a recent study. The researchers used representative data from five African countries with over 32,000 child observations. If the children had a diet containing...
www.sciencedaily.com
Intake of micronutrients high in animal-source foods is associated with better growth in rural Kenyan school children | British Journal of Nutrition | Cambridge Core
Intake of micronutrients high in animal-source foods is associated with better growth in rural Kenyan school children - Volume 95 Issue 2
Effects of animal source foods, with emphasis on milk, in the diet of children in low-income countries - PubMed
This review evaluates evidence for benefits of including animal source foods (ASF) in the diets of children in developing countries. In observational studies, a higher usual intake of ASF in such countries is associated with better growth, status of some micronutrients, cognitive performance...
pubmed.ncbi.nlm.nih.gov
There are clearly more things that I will do,this is just a starting point,I will experiment with Biohacking. I have everything and everyone against me,but I will somehow do it!
lmfao
