How do SOME sarms cause cancer??

Alex_notmogging

Alex_notmogging

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i will try to keep it as short as possible .

Ive been digging a bit into threads about sarms and ive noticed in every thread it say ,, SARMs causes cancer ,,

and im wondering how do people on this forum figured that out ?

For example ostarine , one of the safest SARMs known to humas atm . Ive tried to do the research and for me the accusations of ,, Sarms causing cancer ,, doesnt really make sense to me and this is why

( in this whole time , im talking about ostarine because its a decently mild SARM )

1. Studies

There is no Human study that properly says that Sarms are causing cancer . ( pretty dumb argument but i had to add it )

2. Logic biology + studys

SARMs selectively activate androgen receptors in muscle and bone, sparing most reproductive and prostate tissue. Unlike anabolic steroids, they avoid high systemic androgen load, reducing stimulation of androgen-sensitive tumor pathways.

In some cancers , SARMs even show antiproliferative effects. Without chronic, high-dose AR overactivation, a general carcinogenic effect is biologically implausible.

3. THE ONLY case that sarms could cause cancer

SARMs still bind androgen receptors, which can promote growth in certain hormone-sensitive tissues under specific genetic or pathological conditions.

Rare pre-existing AR-driven tumors could theoretically be stimulated, though this risk appears extremely low without prolonged, high-dose exposure.

--------------

I'm not trying to shift away the fact that SARMs are not unharmful because they can suppress hormones, impact liver enzymes, and alter lipids, even if cancer risk appears minimal.

But i want to debunk the fact that sarms cause cancer because im seeing threads from 2022 till now , that some people say or said that sarms cause cancer

A example is @Orc ( not trying to disrespect u in any way because its obvious that im not a scientist and u prolly have more knowledge to that whole thing , but i want to hear ur current opinion ) but i just simply want to debunk this whole thematic for once

( and yes i acknowledge , that test is healthier for the average person but that not the point )
 
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i will try to keep it as short as possible .

Ive been digging a bit into threads about sarms and ive noticed in every thread it say ,, SARMs causes cancer ,,

and im wondering how do people on this forum figured that out ?

For example ostarine , one of the safest SARMs known to humas atm . Ive tried to do the research and for me the accusations of ,, Sarms causing cancer ,, doesnt really make sense to me and this is why

( in this whole time , im talking about ostarine because its a decently mild SARM )

1. Studies

There is no Human study that properly says that Sarms are causing cancer . ( pretty dumb argument but i had to add it )

2. Logic biology + studys

SARMs selectively activate androgen receptors in muscle and bone, sparing most reproductive and prostate tissue. Unlike anabolic steroids, they avoid high systemic androgen load, reducing stimulation of androgen-sensitive tumor pathways.

In some cancers , SARMs even show antiproliferative effects. Without chronic, high-dose AR overactivation, a general carcinogenic effect is biologically implausible.

3. THE ONLY case that sarms could cause cancer

SARMs still bind androgen receptors, which can promote growth in certain hormone-sensitive tissues under specific genetic or pathological conditions.

Rare pre-existing AR-driven tumors could theoretically be stimulated, though this risk appears extremely low without prolonged, high-dose exposure.

--------------

I'm not trying to shift away the fact that SARMs are not unharmful because they can suppress hormones, impact liver enzymes, and alter lipids, even if cancer risk appears minimal.

But i want to debunk the fact that sarms cause cancer because im seeing threads from 2022 till now , that some people say or said that sarms cause cancer

A example is @Orc ( not trying to disrespect u in any way because its obvious that im not a scientist and u prolly have more knowledge to that whole thing , but i want to hear ur current opinion ) but i just simply want to debunk this whole thematic for once

( and yes i acknowledge , that test is healthier for the average person but that not the point )
dnr
 
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Bump
 
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No good replies over
 
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There's no proof Ostarine causes cancer afaik.

There was some SARMS study a while back and the rodents developed tumors. That scared the hell out of me from trying SARMS. But the drug wasn't one of the usual ones that gets mentioned here and the rodents were basically mega dosed way higher than what we take on a per kg basis. Also rodents metabolize drugs differently and shit to us so it's not 1-to-1.
 
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There's no proof Ostarine causes cancer afaik.

There was some SARMS study a while back and the rodents developed tumors. That scared the hell out of me from trying SARMS. But the drug wasn't one of the usual ones that gets mentioned here and the rodents were basically mega dosed way higher than what we take on a per kg basis. Also rodents metabolize drugs differently and shit to us so it's not 1-to-1.
Yea the point is just , there is no proof because it doesnt make biologically sense

Rodent tumor findings came from extreme doses and species with very different metabolism, making results poor predictors for humans like u already mentioned
 
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i will try to keep it as short as possible .

Ive been digging a bit into threads about sarms and ive noticed in every thread it say ,, SARMs causes cancer ,,

and im wondering how do people on this forum figured that out ?

For example ostarine , one of the safest SARMs known to humas atm . Ive tried to do the research and for me the accusations of ,, Sarms causing cancer ,, doesnt really make sense to me and this is why

( in this whole time , im talking about ostarine because its a decently mild SARM )

1. Studies

There is no Human study that properly says that Sarms are causing cancer . ( pretty dumb argument but i had to add it )

2. Logic biology + studys

SARMs selectively activate androgen receptors in muscle and bone, sparing most reproductive and prostate tissue. Unlike anabolic steroids, they avoid high systemic androgen load, reducing stimulation of androgen-sensitive tumor pathways.

In some cancers , SARMs even show antiproliferative effects. Without chronic, high-dose AR overactivation, a general carcinogenic effect is biologically implausible.

3. THE ONLY case that sarms could cause cancer

SARMs still bind androgen receptors, which can promote growth in certain hormone-sensitive tissues under specific genetic or pathological conditions.

Rare pre-existing AR-driven tumors could theoretically be stimulated, though this risk appears extremely low without prolonged, high-dose exposure.

--------------

I'm not trying to shift away the fact that SARMs are not unharmful because they can suppress hormones, impact liver enzymes, and alter lipids, even if cancer risk appears minimal.

But i want to debunk the fact that sarms cause cancer because im seeing threads from 2022 till now , that some people say or said that sarms cause cancer

A example is @Orc ( not trying to disrespect u in any way because its obvious that im not a scientist and u prolly have more knowledge to that whole thing , but i want to hear ur current opinion ) but i just simply want to debunk this whole thematic for once

( and yes i acknowledge , that test is healthier for the average person but that not the point )
Everything causes cancer at a certain dose
 
There's no proof Ostarine causes cancer afaik.

There was some SARMS study a while back and the rodents developed tumors. That scared the hell out of me from trying SARMS. But the drug wasn't one of the usual ones that gets mentioned here and the rodents were basically mega dosed way higher than what we take on a per kg basis. Also rodents metabolize drugs differently and shit to us so it's not 1-to-1.
You're talking about Cardarine.

Cardarine isn't a sarm.
 
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