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God make my neurotransmitters great inc
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1. Nickel in hydrogenated oils is usually stressed, as this is actually somewhat toxic, and is generally found at around one part per million.⁽²⁾⁽³⁾ But for some reason, aluminum isn't looked for as often. But it has been found, of course, since it's always associated with the Raney catalyst.
'This interest derives from the association of trace metals with the origin of oils (soils and fertilizers), metal processing equipment, and catalysts used for hydrogenation; toxicity of edible oils and fats; and the effect of trace metals on the characteristics of finished products, such as color and taste.' ―Farhan⁽⁴⁾
In hydrogenated oils, aluminum can be found in part per million concentrations:⁽⁴⁾
Now this isn't your ionic, one atom aluminum (Al³⁺); these are small micro‐ and nanometer‐sized particles which cannot be chelated by citrate, malate, nor silica, in the body. Some of these particles would be expected to be persorbed, as particles of similar size have been shown to do.⁽⁵⁾
2. Aluminum partitions around nerves because it has a high affinity for phosphate and the microtubule‐associated proteins are highly phosphorylated. This has been detected by a number of ways, and there is certainly no lack of evidence for this.⁽⁶⁾
I think it would be fair to say that aluminum has a peculiar affinity for nerves.
3. Aluminum actively crosslinks phosphorylated nerve proteins in vitro more than any other physiological ion. This helps to provide a mechanistic explanation, as it's well‐known to strongly bind phosphoryl groups. The phophoryl groups on proteins are usually bound to the amino aid tyrosine, but also to serine and threonine—basically to any hydroxy amino acid.
This affinity has been shown by gel electrophoresis. The aggregates shift in a gradient as they increase in size and density:⁽⁷⁾
Aluminum has been used by the hide tanning industry for this very reason.⁽⁸⁾
4. Aluminum‐crosslinked myelin proteins cause an inflammatory response, which is sometime called an 'autoimmune disease.' This is a misnomer, as the Greek prefix auto denotes that the body is attacking itself. This is only partly true, since the Al³⁺ ion is unnatural and responsible for changing the geometry of the phosphorylated myelin proteins. This is another case of faulty, irresponsible, and perhaps even deceptive semantics used to hide the fact of what's really going on.
Macrophages and killer T cells try to engulf the Al³⁺–protein complexes, and this is the so‐called 'autoimmunity.' Another deceptive, although correct, term is 'misfolded tau:'
'It has been hypothesized that misfolded tau protein could be a mediator of the inflammatory response in human tauopathies. Here we show that neurodegenerative lesions caused by human truncated tau promote inflammatory response manifested by upregulation of immune-molecules (CD11, CD18, CD4, CD45 and CD68) and morphological activation of microglial cells in a rat model of tauopathy. In parallel, the innate immune brain response promotes activation of MHC class II positive blood-borne leukocytes and their influx into the brain parenchyma.' ―Zilka⁽⁸⁾
The criticism of this term is similar to the criticism made of the 'passive voice,' as the adjective 'misfolded' does not imply attribution. A more accurate description, written in a more active voice, would be a τ‐protein–Al³⁺ complex.
Themisfoled tau τ‐protein–Al³⁺ complex attracts leukocytes, or immune cell macrophages which then attempt to engulf this tangle.
5. Nonhydrogenated coconut oil is completely safe because it has no aluminum. Millions of people can testify that neither coconuts, nor its oil, will produce neurodegeneration. And such an idea hasn't even a logical explanation.
'This interest derives from the association of trace metals with the origin of oils (soils and fertilizers), metal processing equipment, and catalysts used for hydrogenation; toxicity of edible oils and fats; and the effect of trace metals on the characteristics of finished products, such as color and taste.' ―Farhan⁽⁴⁾
In hydrogenated oils, aluminum can be found in part per million concentrations:⁽⁴⁾
Now this isn't your ionic, one atom aluminum (Al³⁺); these are small micro‐ and nanometer‐sized particles which cannot be chelated by citrate, malate, nor silica, in the body. Some of these particles would be expected to be persorbed, as particles of similar size have been shown to do.⁽⁵⁾
2. Aluminum partitions around nerves because it has a high affinity for phosphate and the microtubule‐associated proteins are highly phosphorylated. This has been detected by a number of ways, and there is certainly no lack of evidence for this.⁽⁶⁾
I think it would be fair to say that aluminum has a peculiar affinity for nerves.
3. Aluminum actively crosslinks phosphorylated nerve proteins in vitro more than any other physiological ion. This helps to provide a mechanistic explanation, as it's well‐known to strongly bind phosphoryl groups. The phophoryl groups on proteins are usually bound to the amino aid tyrosine, but also to serine and threonine—basically to any hydroxy amino acid.
This affinity has been shown by gel electrophoresis. The aggregates shift in a gradient as they increase in size and density:⁽⁷⁾
Aluminum has been used by the hide tanning industry for this very reason.⁽⁸⁾
4. Aluminum‐crosslinked myelin proteins cause an inflammatory response, which is sometime called an 'autoimmune disease.' This is a misnomer, as the Greek prefix auto denotes that the body is attacking itself. This is only partly true, since the Al³⁺ ion is unnatural and responsible for changing the geometry of the phosphorylated myelin proteins. This is another case of faulty, irresponsible, and perhaps even deceptive semantics used to hide the fact of what's really going on.
Macrophages and killer T cells try to engulf the Al³⁺–protein complexes, and this is the so‐called 'autoimmunity.' Another deceptive, although correct, term is 'misfolded tau:'
'It has been hypothesized that misfolded tau protein could be a mediator of the inflammatory response in human tauopathies. Here we show that neurodegenerative lesions caused by human truncated tau promote inflammatory response manifested by upregulation of immune-molecules (CD11, CD18, CD4, CD45 and CD68) and morphological activation of microglial cells in a rat model of tauopathy. In parallel, the innate immune brain response promotes activation of MHC class II positive blood-borne leukocytes and their influx into the brain parenchyma.' ―Zilka⁽⁸⁾
The criticism of this term is similar to the criticism made of the 'passive voice,' as the adjective 'misfolded' does not imply attribution. A more accurate description, written in a more active voice, would be a τ‐protein–Al³⁺ complex.
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5. Nonhydrogenated coconut oil is completely safe because it has no aluminum. Millions of people can testify that neither coconuts, nor its oil, will produce neurodegeneration. And such an idea hasn't even a logical explanation.
