If you want to be happy, focus LESS on Dopamine and MORE on Serotonin. HIGH effort thread

[Dior]

High effort thread

repost since I put it in wrong subforum

If you want to live a happier life, you should focus on serotoninmaxxing. Many ppl here think that dopamine > everything but it couldn't be further from truth.

Serotonin

Serotonin is a neurotransmitter in the brain mainly responsible for the feeling of happiness and wellbeing.

Dopamine

Dopamine is a neurotransmitter in the brain responsible for the feeling of reward, motivation and pleasure. It is known that dopamine played a huge role in our species survival and evolution.

We are constantly bombard with sources of quick and cheap dopamine in every day life. Internet, video games, porn, social media, junkfood and even music. Of course, all this cant be healthy for you, and as a result of doing too much of these activities, you will find that your dopamine receptors get desensitized, reducing your motivation, drive and sense of well being.

What you should do is limit those dopamine-releasing activities and involve more in things that benefit your serotonin. Aka, start meditating (inb4 cope), cut out shitty food, start exercising (inb4 gymcel), limit your time spend on video games or jacking off and get a fucking proper sleep schedule (really important). Ever since I've started meditating waking up early and going to sleep at the same time every night I've felt much better and had more time and motivation to do shit.

Serotonin truly mogs dopamine because it allows you feel contempt and happy in a long-term manner.

To further prove my point, Im gonna use some real life examples. MDMA (aka molly/ecstasy) is a drug that releases great quantities of serotonin in the brain. It was proven to successfully cure depression and PTSD symptoms in many people without having a high addicting potential. I remember I took 150mg of Molly once and I've felt incredible happiness and contempt. It was the most overwhelming rush of happiness ever, and it turned into a nice afterglow that lasted the following days. I enjoyed it greatly, yet after such experience I never really craved it again. Why? Because it was enough and I was satisfied. Now if you look at Meth (it also acts on serotonin receptors but only a tiny amount like 0.1%) or Crack, they act on dopamine receptors giving you an incredible rush of pleasure. They don't even come close near good mdma in terms of euphoria, and yet far more people are addicted to them and will literally kill and suck dick for both of these fiendish drug. Why? Thats because your brain is designed to crave that short term pleasure rush and it will always want more. It surely did help back in cavemen times when Chad got useful dopamine rush when killing deers and eating its meat, but in todays world we are provided with cheap dopamine releasing activities that don't contribute to your survival/wellbeing.

Also if you're planning to do mdma (which i dont condone), you should wait at least 3 months in between.

Tldr: Do less things that release short-term dopamine (fapping, junkfood, porn, games, distractions) and do things that benefit your serotonin in the long term (good diet, exercising, proper sleep, mindfulness and meditation).

Not only you will feel better in the long term from the serotonin, but your dopamine receptors will sensitize again making you feel full of energy, drive and motivation.

We're all gonna make it kings.

 

[Deleted member 6400]

good thread bro

 

[Cope]

Yes, but I just want to clarify it's not about having more serotonin. Too much serotonin is just as bad as not enough. It also works more as a neuromodulator, so it serves to balance any excessive excitatory neurotransmitter firing in the brain such as dopamine (dopamine is also inhibitory), norepinephrine, and glutamate. Therefore anything that agonizes these neurotransmitters can simultaneously reduce serotonin.

I feel promoting not just your 5-HT but your GABA system as well is essential in curing mentalceldom. In fact, a lot of people who may think they're low serotonin might actually be low GABA since the symptoms of deficiencies in both are almost identical. I'm still in just the beginning stages of finding the right substances for this, but once I start to experiment more I will hopefully find the definitive neurotransmitter-maxxing protocol.

Btw where did you read that meth acts only on 0.1% of serotonin? Meth is so much smoother than other amphetamines, the effects it has on serotonin is definitely very noticeable.

 

[Vitruvian]

I have nothing to do but workout, meditate and jerk off bruh. All those things make up 10% of your day

 

[Dior]

Yes, but I just want to clarify it's not about having more serotonin. Too much serotonin is just as bad as not enough. It also works more as a neuromodulator, so it serves to balance any excessive excitatory neurotransmitter firing in the brain such as dopamine (dopamine is also inhibitory), norepinephrine, and glutamate. Therefore anything that agonizes these neurotransmitters can simultaneously reduce serotonin.

I feel promoting not just your 5-HT but your GABA system as well is essential in curing mentalceldom. In fact, a lot of people who may think they're low serotonin might actually be low GABA since the symptoms of deficiencies in both are almost identical. I'm still in just the beginning stages of finding the right substances for this, but once I start to experiment more I will hopefully find the definitive neurotransmitter-maxxing protocol.

Btw where did you read that meth acts only on 0.1% of serotonin? Meth is so much smoother than other amphetamines, the effects it has on serotonin is definitely very noticeable.

True, having too much serotonin can be even deadly (SS).

Idk about gaba since i've heard its mostly reponsible for anxiety and fear. Imma look more into it

Its interesting you say that meth is much smoother that other amps since I tried it once but was tweaking too much couldn't even concentrate (unlike traditional amps) and everywhere i read everyone has similar report and that serotonin effects are not even noticeable (thats why I just said 0.1% since i presumed it releases a very tiny portion of serotonin compared to dopamine)

 

[OBE]

Amazing thread tbh, good information!

 

[curryslayerordeath]

no serotonin for my face

 

[Cope]

Its interesting you say that meth is much smoother that other amps since I tried it once but was tweaking too much couldn't even concentrate (unlike traditional amps) and everywhere i read everyone has similar report and that serotonin effects are not even noticeable (thats why I just said 0.1% since i presumed it releases a very tiny portion of serotonin compared to dopamine)

It must react differently to my neurochemistry then. When I take traditional amphetamines like Adderall I get easily agitated and annoyed, that's more of what I meant. I experienced a lot of euphoria when I took Meth though, almost comparable to the time I did MDMA.

 

[Deleted member 2756]

good thread, I'd like more people talking about the topic on this forum, but, you're wrong, serotonin is the devil, dopamine reigns supreme. There's a reason why serotonin reuptake inhibitors cause impotency, erectile dysfunction, and further worsen depressive symptoms. Serotonin rapes metabolism, increases chances of insulin resistance, decreases androgens, and depletes the brain of dopamine and other catecholamine monoamines, serotonin receptor antagonists INCREASE life-span, whereas reuptake inhibitors do the opposite. High serotonin is linked to autism developing in children, autistic children are also known to have higher levels of serotonin than normal children, serotonin is also linked to anxiety, whereas SSRI companies promote it has anxiolytic, serotonin also increases the rate of bone resorption and has been shown to worsen patients with osteoporosis.

Most of us are serotonin DOMINANT, because of the deprivation of dopamine that occurs due to the easily accessible stimulation that requires no work to obtain with little reward to come along with it, another thing to mention is the insane amount of tryptophan that we consume in our modern diets, in comparison to the amount of taurine we get. Instead of trying to increase serotonin, we should in fact be focussing on dopamine, because dopamine also regulates mood and doesn't cause other issues.

The dark side of Serotonin, exposed.

Serotonin truly mogs dopamine because it allows you feel contempt and happy in a long-term manner.

they also induce the latter, MDMA might make you feel euphoric but it will also make you a submissive faggot who won't be able to get his dick up. Luckily MDMA depletes the brain of serotonin after discontinuation, which is a good thing.

I feel promoting not just your 5-HT but your GABA system

if only the GABAergic system wasn't so difficult to alter, feels bad man.

 

[Solidcoin]

You're trolling if you think serotonin > dopamine

Serotonin is always dominant in low status males for a reason

 

[Deleted member 2756]

I assume releasing agents such as MDMA are less of a detriment than reuptake inhibitors?

reuptake inhibitors aren't as bad, because they only increase serotonin a bit above average if I recall correctly.
whereas MDMA will literally flood your brain with serotonin, I don't exactly know the mechanism in which it depletes the brain of serotonin afterward, but I'm interested.

high androgens, high dopamine, and low serotonin is literally the recipe for success, obtaining such a profile is insanely difficult though.

 

[Dior]

good thread, I'd like more people talking about the topic on this forum, but, you're wrong, serotonin is the devil, dopamine reigns supreme. There's a reason why serotonin reuptake inhibitors cause impotency, erectile dysfunction, and further worsen depressive symptoms. Serotonin rapes metabolism, increases chances of insulin resistance, decreases androgens, and depletes the brain of dopamine and other catecholamine monoamines, serotonin receptor antagonists INCREASE life-span, whereas reuptake inhibitors do the opposite. High serotonin is linked to autism developing in children, autistic children are also known to have higher levels of serotonin than normal children, serotonin is also linked to anxiety, whereas SSRI companies promote it has anxiolytic, serotonin also increases the rate of bone resorption and has been shown to worsen patients with osteoporosis.

Most of us are serotonin DOMINANT, because of the deprivation of dopamine that occurs due to the easily accessible stimulation that requires no work to obtain with little reward to come along with it, another thing to mention is the insane amount of tryptophan that we consume in our modern diets, in comparison to the amount of taurine we get. Instead of trying to increase serotonin, we should in fact be focussing on dopamine, because dopamine also regulates mood and doesn't cause other issues.

The dark side of Serotonin, exposed.

they also induce the latter, MDMA might make you feel euphoric but it will also make you a submissive faggot who won't be able to get his dick up. Luckily MDMA depletes the brain of serotonin after discontinuation, which is a good thing.

if only the GABAergic system wasn't so difficult to alter, feels bad man.

great info man thanks for sharing

 

[Deleted member 2756]

great info man thanks for sharing

how did you feel after mdma?
I remember being hornier than ever, probably accountable due to the decrease in serotonin synthesis.

 

[Deleted member 2756]

obviously MDMA makes you depressed for like 3 days after - that's much harsher than reuptake inhibitors, but I guess I was talking under the assumption that the MDMA is only taken every few months and SSRIs are taken everyday as prescribed.

sure, ssri's will also flood your brain with serotonin, thus depleting dopamine, homeostasis is key.

anyone can inject T so that's not an issue. high dopamine is very hard to sustain, but I suppose anyone can have it at some points if they take amphetamines. do you have any thoughts on medications such as wellbutrin?

wellbutrin is a dopamine-norepinephrine reuptake inhibitor, right?
it's prescribed to depressed men that can't take SSRI's because of sexual side effects, there are far better ways to increase dopamine, you can do it naturally via diluting tryptophan within the brain with branch chain amino acids and gelatin, or just eating a diet lower in tryptophan. If you wish to take the pharmaceutical route than a combination of both cyproheptadine and a dopamine receptor agonist would work well, maybe agomelatine at night for further 5-HT2 receptor antagonism. Increasing your DHT works well also. DHT has been shown to deplete the brain of tryptophan, thus decreasing serotonin synthesis, another reason why finasteride cucks are fucked, DHT also has a direct effect on the expression of the serotonin receptors via it's antagonizing effect upon estradiol (estradiol plays an important role in the expression of the receptors, whilst also upregulating them and increasing the density within the sites).

fucking around with this type of shit is risky, just as risky as androgens and so forth. Always take the natural route before taking drugs.

 

[Dior]

how did you feel after mdma?
I remember being hornier than ever, probably accountable due to the decrease in serotonin synthesis.

I felt great for the next few days. Ive heard ppl talking how they feel depressed but thats probably from abuse, overheating, doses more than 200mg and lack of eating and sleeping. Didnt really notice a difference in libido tbh

 

[NoBonezForMoanz]

@Dyorotic2 what do you think about using MDMA once to reduce the Serotonin concentration to form a new low baseline in a reasonably healthy individual?
Could be helpful for some people who've accumulated too much Serotonin during their lives and got problems caused by a fucked up environment, like hormones, cuck drugs or ptsd as a veteran (cuz that's where it's already being used)

 

[Deleted member 2756]

@Dyorotic2 what do you think about using MDMA once to reduce the Serotonin concentration to form a new low baseline in a reasonably healthy individual?

I can't answer that question at the moment, I'm still researching the extent to which MDMA depletes serotonin after discontinuation, how long for, at the expense of other neurochemicals? etc. If you go on the Ray peat forum you'll ofttimes see threads and discussions pop up surrounding the topic, it seems as though taking this route could work, but in the short term rather than the long.

 

[Lars]

MDMA IS THE BEST SUBSTANCE EVER

 

[prgfromnl]

MDMA IS THE BEST SUBSTANCE EVER View attachment 379226

Agreed

 

[Lars]

View attachment 379229

Agreed

Zo veel geluk dat wij in Nederland wonen

 

[prgfromnl]

@Dior There is also a supplement called 5-htp for serotonin. you should look into it, it increases serotonin I'm pretty sure

Zo veel geluk dat wij in Nederland wonen

niet te vaak snoepen he

 

[Lars]

@Dior There is also a supplement called 5-htp for serotonin. you should look into it, it increases serotonin I'm pretty sure

niet te vaak snoepen he

hahaha nee nee minimaal 3 maanden wachten

 

[Deleted member 5522]

Extremely high iq, I can confirm this.

 

[WideZygos]

High effort thread

repost since I put it in wrong subforum

If you want to live a happier life, you should focus on serotoninmaxxing. Many ppl here think that dopamine > everything but it couldn't be further from truth.

Serotonin
View attachment 373324
Serotonin is a neurotransmitter in the brain mainly responsible for the feeling of happiness and wellbeing.

Dopamine
View attachment 373323
Dopamine is a neurotransmitter in the brain responsible for the feeling of reward, motivation and pleasure. It is known that dopamine played a huge role in our species survival and evolution.

We are constantly bombard with sources of quick and cheap dopamine in every day life. Internet, video games, porn, social media, junkfood and even music. Of course, all this cant be healthy for you, and as a result of doing too much of these activities, you will find that your dopamine receptors get desensitized, reducing your motivation, drive and sense of well being.

What you should do is limit those dopamine-releasing activities and involve more in things that benefit your serotonin. Aka, start meditating (inb4 cope), cut out shitty food, start exercising (inb4 gymcel), limit your time spend on video games or jacking off and get a fucking proper sleep schedule (really important). Ever since I've started meditating waking up early and going to sleep at the same time every night I've felt much better and had more time and motivation to do shit.

Serotonin truly mogs dopamine because it allows you feel contempt and happy in a long-term manner.

To further prove my point, Im gonna use some real life examples. MDMA (aka molly/ecstasy) is a drug that releases great quantities of serotonin in the brain. It was proven to successfully cure depression and PTSD symptoms in many people without having a high addicting potential. I remember I took 150mg of Molly once and I've felt incredible happiness and contempt. It was the most overwhelming rush of happiness ever, and it turned into a nice afterglow that lasted the following days. I enjoyed it greatly, yet after such experience I never really craved it again. Why? Because it was enough and I was satisfied. Now if you look at Meth (it also acts on serotonin receptors but only a tiny amount like 0.1%) or Crack, they act on dopamine receptors giving you an incredible rush of pleasure. They don't even come close near good mdma in terms of euphoria, and yet far more people are addicted to them and will literally kill and suck dick for both of these fiendish drug. Why? Thats because your brain is designed to crave that short term pleasure rush and it will always want more. It surely did help back in cavemen times when Chad got useful dopamine rush when killing deers and eating its meat, but in todays world we are provided with cheap dopamine releasing activities that don't contribute to your survival/wellbeing.

Also if you're planning to do mdma (which i dont condone), you should wait at least 3 months in between.

Tldr: Do less things that release short-term dopamine (fapping, junkfood, porn, games, distractions) and do things that benefit your serotonin in the long term (good diet, exercising, proper sleep, mindfulness and meditation).

Not only you will feel better in the long term from the serotonin, but your dopamine receptors will sensitize again making you feel full of energy, drive and motivation.

We're all gonna make it kings.

You didn’t take molly stop lying.. the next days literally feel like your dying 100x times worse than alcohol hangover bc your serotonin is gone stop larping nigga

 

[Deleted member 6963]

@kjsbdfiusdf

 

[Deleted member 13746]

Serotonin just like estrogen and cortisol will wreak havoc on the human body leading to a mentally and physically diseased state. Dopamine is protective and beneficial while, serotonin is the opposite. The idea is to blast a pro-dopamine compound alongside a serotonin anatagonist. Adopting a lifestyle that is pro-dopamine and anti-serotonin is also key. Things that increase Serotonin (Masturbation, Junk Food, Sedentary, Television, Darkness etc..) vs Dopamine (Training, Learning, Traveling, Socializing, Sunlight etc..).

 

[Deleted member 13746]

^^^^^^^^^^^^^^^^^^^^^^^^^^^
KJ's Final Experiment is to ascend humanity.

 

[Deleted member 2095]

Reading this in the McDrive lane man

 

[Mysticcc]

 

[Deleted member 13746]

Reading this in the McDrive lane man

Burger with Cheese/Beef+Coke+No Fries/Sauce and that is actually a solid meal. Plenty of saturated fats, protein and sucrose which is anabolic. The problem is that it is GMO and cooked in vegetable oil.

 

[Deleted member 643]

Fuck being happy. I want to pursue power and control over my circumstances.

 

[TrestIsBest]

Who wants to be contempt with life? I want to strive for more. If you want to be contempt in the moment, just shoot up heroin