Ychassa
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HOW TO INCREASE BONEMASS
Bisphosphonates
Denosumab (Prolia)
Strontium Ranelate
Steroids ( most effective)
- We all know why we want more bone density, it makes your face more defined and attractive
- it will increase dimorphism so watch out prettyboys if you want your low dimophism
BLUE = protects against osteoclasts (cells that break down bone)
GREEN = Promotes bone formation
PUPLE = MIX
Bisphosphonates
- How They Work: Bisphosphonates work by attaching to the surface of bones and getting absorbed by osteoclasts, the cells responsible for breaking down old bone tissue. Once inside the osteoclasts, they inhibit certain enzymes crucial for bone breakdown, thereby slowing down the process of bone resorption. This inhibition allows the bone-building cells, called osteoblasts, more time to lay down new bone tissue, resulting in an overall increase in bone density.
- Side Effects: Some people may experience gastrointestinal issues such as upset stomach or heartburn. Rarely, long-term use of bisphosphonates has been associated with a condition called osteonecrosis of the jaw (ONJ),
EXAMPLES OF Bisphosphonates:- Alendronate (Fosamax)
- Risedronate (Actonel)
- Ibandronate (Boniva)
- Zoledronic acid (Reclast)
Denosumab (Prolia)
- How It Works: Denosumab is a type of medication known as a monoclonal antibody (cells made to attack something specefik). It works by targeting and binding to a protein called RANKL (Receptor Activator of Nuclear Factor Kappa-B Ligand), which is essential for the activation and function of osteoclasts. By blocking RANKL, denosumab prevents osteoclasts from breaking down bone tissue, thereby promoting bone density.
- Side Effects: Common side effects may include infections, skin reactions at the injection site, and low levels of calcium in the blood. Additionally, denosumab has been associated with an increased risk of ONJ, similar to bisphosphonates.
Strontium Ranelate
- How It Works: Strontium ranelate is a compound containing the element strontium. It works by simultaneously reducing bone resorption (the breakdown of old bone) and stimulating bone formation. The exact mechanism of action is not fully understood, but strontium ranelate has been shown to promote the differentiation of osteoblasts (bone-forming cells) and inhibit osteoclast activity.
- Side Effects: Common side effects may include gastrointestinal disturbances such as nausea and diarrhea. Additionally, there have been concerns about potential cardiovascular risks associated with strontium ranelate use.
- How They Work: Parathyroid hormone analogues mimic the action of parathyroid hormone (PTH), which is a natural hormone involved in calcium regulation and bone metabolism. these analogues stimulate osteoblast activity, leading to increased bone density.
- Side Effects: Potential side effects may include hypercalcemia (high calcium levels in the blood), leg cramps, dizziness, and, rarely, osteosarcoma (a type of bone cancer).
Steroids ( most effective)
Human Growth Hormone (HGH), least sides, most effective for bonemass.
- Mechanism: Increases IGF-1 production, stimulating bone growth and density.
- Dose: 3iu+ per day
- Side Effects:
- Joint pain, carpal tunnel syndrome.
- Water retention, increased blood sugar levels.
- Rarely, growth of unwanted tissues (ogremaxxing).
Testosterone (Test), worse than hgh for bonemass, you wont ogremaxx too much tho, still very good for bonemass
- Mechanism: Promotes bone density by stimulating osteoblasts and increasing calcium absorption.
- Dose: 200 mg+ per week.
- Side Effects:
- Acne, oily skin, Hair loss( if you dont use dutasteride)
- gynecomastia (countered by ai, do bloodwork, or you will become retarded since the brain needs estrogen).
- Suppressed natural testosterone production. (you will be dependant on it, for the rest of your life, if you do it long enough without pct)
- infertility, your balls stop working (can be countered with clomid)
Trenbolone (Tren), not worth it IMO, start with the other things, this should be a last resort.
- Mechanism: Increases IGF-1 and enhances nitrogen retention, indirectly supporting bone health.
- Dose: 100 mg+ per week
- Side Effects:
- Severe testosterone suppression.
- Anxiety, insomnia, aggression.
- Cardiovascular strain (worsened cholesterol profile).
- Liver and kidney stress.
- every testosterone side effect but worse
