Introduction to mk-677

[idkmanimao]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

 

[Deleted member 151683]

This is a repost of another post on here

 

[idkmanimao]

This is a repost of another post on here

not really tbh, it's not in guide section

 

[MaracasMogs]

67

 

[idkmanimao]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

bump

 

[Copercel]

Mk is shit. DNR

 

[idkmanimao]

Mk is shit. DNR

-never tried it

 

[Copercel]

-never tried it

Doesn’t mean it’s not shit.

You didn’t try it aswell.

 

[AbuSdanteet]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

There’s so many of these intro to mk677 guides. No need to reinvent the wheel

 

[AbuSdanteet]

also, anamorelin mogs mk677.

Anamorelin - The SUPERPOWERED MK677 (MUST-READ)

Since you guys hate longer threads, I'll make this one short. What is Anamorelin: Anamorelin is a medically approved oral growth hormone secretagogue known for its anabolic and appetite-enhancing effects. It has a half-life of 6-7 hours and is taken in dosages of 25-50-75 MG. Anamorelin...

looksmax.org

 

[AbuSdanteet]

Good thread tho nonetheless

Don’t be sad

 

[idkmanimao]

also, anamorelin mogs mk677.

Anamorelin - The SUPERPOWERED MK677 (MUST-READ)

Since you guys hate longer threads, I'll make this one short. What is Anamorelin: Anamorelin is a medically approved oral growth hormone secretagogue known for its anabolic and appetite-enhancing effects. It has a half-life of 6-7 hours and is taken in dosages of 25-50-75 MG. Anamorelin...

looksmax.org

thanks a lot bhai, so can you gain facial bone mass from this? (14)

 

[AbuSdanteet]

thanks a lot bhai, so can you gain facial bone mass from this? (14)

I don’t think so. But if it does, it would be minute. Nothing compared to TestE

 

[idkmanimao]

I don’t think so. But if it does, it would be minute. Nothing compared to TestE

so I should just run test e? what else? gh, igf-1 LR3, anything else? and what age would be the best for it? i'm 14, can't take it right now because I need money and to convince my parents so I dont get kicked out the house. probs about 16-17

 

[elkkkk]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

bro literally just copy pasted my post jfl https://looksmax.org/threads/why-mk-677-is-actually-op.1550663/#post-22163245

 

[AbuSdanteet]

so I should just run test e? what else? gh, igf-1 LR3, anything else? and what age would be the best for it? i'm 14, can't take it right now because I need money and to convince my parents so I dont get kicked out the house. probs about 16-17

What is your goal? Facial dimorphism, height, etc.

 

[idkmanimao]

bro literally just copy pasted my post jfl https://looksmax.org/threads/why-mk-677-is-actually-op.1550663/#post-22163245

yeah, but I put it in guide section, yw bhai

 

[idkmanimao]

What is your goal? Facial dimorphism, height, etc.

facial bone mass and dimorphsim, I already have hieght (6'3) i'm just pretty boneless, trying to increase zygos and mandible width/bigonial width for hollows

 

[Copercel]

yeah, but I put it in guide section, yw bhai

Then what’s the point hahaha

 

[idkmanimao]

Then what’s the point hahaha

reps, I haven't posted anything lately yet

 

[6´3 LTN]

thanks a lot bhai, so can you gain facial bone mass from this? (14)

You the same guy who called me retarded

 

[elkkkk]

reps, I haven't posted anything lately yet

 

[idkmanimao]

You the same guy who called me retarded

Yes, you are retarded

 

[chadisbeingmade]

Dogshit thread. Don't need to read. Never write a thread again.

 

[AbuSdanteet]

facial bone mass and dimorphsim, I already have hieght (6'3) i'm just pretty boneless, trying to increase zygos and mandible width/bigonial width for hollows

6’3 at 14 is actually wild. You can probably reach 6’5 minimum by the time ur 18.

For facial dimorphism (that won’t stunt your height growth as well). Take hgh, but ur 14. So you shouldn’t even be worrying at this. Your face continues to develop until you’re 25.

 

[chadisbeingmade]

Your face continues to develop until you’re 25.

Sorry to end your hopes and dreams of becoming Maher at 25 years old but JFL 25 my fucking ass.

Nothing compared to TestE

I knew you were clueless, but not his clueless JFL. Time to drop the cope and pick up the rope.

Verry funny that you mentioned enanthate as if the ester makes a singular fucking difference as well LOL.

 

[elkkkk]

Dogshit thread. Don't need to read. Never write a thread again.

whats wrong

 

[idkmanimao]

View attachment 3972347

View attachment 3972349

I knew you were clueless, but not his clueless JFL. Time to drop the cope and pick up the rope.

so my mandible and zygos have a chance of growing? both at about 13.5-14 cms right now.

 

[chadisbeingmade]

so my mandible and zygos have a chance of growing? both at about 13.5-14 cms right now.

You are 14. Look at the fucking table and use your brain.

 

[idkmanimao]

You are 14. Look at the fucking table and use your brain.

I did nigga, I just want to verify.....

 

[elkkkk]

Dogshit thread. Don't need to read. Never write a thread again.

Just say whats wrong or false i ll wait

 

[AbuSdanteet]

Sorry to end your hopes and dreams of becoming Maher at 25 years old but JFL 25 my fucking ass.

Longitudinal changes in the adult facial profile - PubMed

Longitudinal growth changes in the adult craniofacial complex were studied for 24 white male and 23 white female subjects between the ages of 18 and 42 years who had Class I or end-to-end molar relationships and no excessive protrusions or retrusions. The male profile straightened with age, and...

pubmed.ncbi.nlm.nih.gov

I knew you were clueless, but not his clueless JFL. Time to drop the cope and pick up the rope.

Verry funny that you mentioned enanthate as if the ester makes a singular fucking difference as well LOL.

You’re one of the dumbest mfers on this forum. I said mk677 is nothing compared to TestE in terms of facial development. If you’re going to argue that some lightweight gh secretagogue drives facial growth and development more than an extremely potent anabolic steroid, then it’s over for you. And yes, I mentioned the ester. So what? That doesn’t necessitate I mentioned it purely because I believe it’s better/worse than its ester counterparts, that’s a strawman fallacy. TestE can drive changes in facial bone structure even in adults.

 

[chadisbeingmade]

You’re one of the dumbest mfers on this forum.

That is you bud. Funny how you only say this after I call you a complete moron and after begging me for help on my profile and threads with the endless fucking tags. Clueless fucker.

MK677 (most dogshit ratpiss compound known to man) JFL. Test for fucking facial bones JFL. Anamorelin for bones or height growth JFL. Jumping for height growth JFL. A TikTokcel can tell from that list you are severely mentally deficient LOL just from that list alone. You are a short, ethnic (JFL), subhuman and have delusions that jumping will make you tall and that Test will grow a zygos out your boneless ethnic face. Even if you jumped your way to 6'6, it's completely over due to your race and balding.

Look at you, begging for help:

And that wasn't even a sarcastic comment (anyone reading will know that you don't have any brain cells):

Look at you, begging for me to reply to your sorry ass:

and again:

Look at you, begging for my approval:

You are genuinely fucking pathetic.

You are so genuinely fucking clueless beyond belief yet you come on my profile begging for advice. Everyone, and I mean everyone, be that @RealSurgerymax or @Jonasㅤㅤ, anyone who has had the displeasure of interacting with your subhuman ass or has seen your post history knows that you are a fucking coping retard.

Anyway, enough from me, happy coping! You won't hear a response, I have removed all greys off the face of .org again. You are below me. You are too retarded to even talk to and provide nothing of substance to this forum, just plain retarded ideas.

I guess there was a reason this was developed and I think it is time to use it again.

"hide greycels feature" has finally released!

FINALLY the "hide greycels feature" has been released! No longer do I have to scroll past and DNR such clueless fucktards, since they don't exist to me anymore. With one press of a button, all greycels are wiped off the face of .org! In action Viewing all threads: While reading a thread...

looksmax.org

Glad to never see another greycels name appear on my screen again.

 

[nosemaxxing]

nigga as i said you ain't gonna get no contributor for this , listen to me instead

 

[AbuSdanteet]

That is you bud. Funny how you only say this after I call you a complete moron and after begging me for help on my profile and threads with the endless fucking tags. Clueless fucker.

MK677 (most dogshit ratpiss compound known to man) JFL. Test for fucking facial bones JFL. Anamorelin for bones or height growth JFL. Jumping for height growth JFL. A TikTokcel can tell from that list you are severely mentally deficient LOL just from that list alone. You are a short, ethnic (JFL), subhuman and have delusions that jumping will make you tall and that Test will grow a zygos out your boneless ethnic face. Even if you jumped your way to 6'6, it's completely over due to your race and balding.

Look at you, begging for help:
View attachment 3972459

And that wasn't even a sarcastic comment (anyone reading will know that you don't have any brain cells):
View attachment 3972481

Look at you, begging for me to reply to your sorry ass:
View attachment 3972462
and again:
View attachment 3972537

Look at you, begging for my approval:
View attachment 3972463

You are genuinely fucking pathetic.

You are so genuinely fucking clueless beyond belief yet you come on my profile begging for advice. Everyone, and I mean everyone, be that @RealSurgerymax or @Jonasㅤㅤ, anyone who has had the displeasure of interacting with your subhuman ass or has seen your post history knows that you are a fucking coping retard.

Anyway, enough from me, happy coping! You won't hear a response, I have removed all greys off the face of .org again. You are below me. You are too retarded to even talk to and provide nothing of substance to this forum, just plain retarded ideas.

I guess there was a reason this was developed and I think it is time to use it again.

"hide greycels feature" has finally released!

FINALLY the "hide greycels feature" has been released! No longer do I have to scroll past and DNR such clueless fucktards, since they don't exist to me anymore. With one press of a button, all greycels are wiped off the face of .org! In action Viewing all threads: While reading a thread...

looksmax.org

Glad to never see another greycels name appear on my screen again.

Dnrd

 

[iblameautistickids]

View attachment 3972459

Unc Why are u leaking my secret pubertymaxxing method

 

[Sadist]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

this nigga would post about anything

 

[idkmanimao]

this nigga would post about anything

Anything for a chance to get BOTB

 

[itsallgenesbtw]

First how does mk-677 even work?

MK-677 (Ibutamoren) is an oral ghrelin receptor agonist that stimulates the pituitary gland to release more growth hormone (GH). This increase in GH also boosts insulin-like growth factor 1 (IGF-1), promoting muscle growth, fat loss, and potentially bone development.



Effects of mk-677 on muscle mass

• Increased gain of lean mass
• Weight gain through the grehlin stimulation
• Possible positive effects on strength
• Better and deeper Sleep resulting in a better recovery

Effects of mk-677 on Hgh and IGF-1 + Cholesterol

• In a human study on mk-677 Hgh increased by about 100% (25mg taken daily)
• In the study a increase of IGF-1 Levels (after 4 weeks on norm young adults) of about 90 % percent was recorded
• Studies showed a slight decrease in LDL Cholesterol

Receptor desensitivation

Even afer 24 months of mk-677 use studies showed that IGF-1 levels were still nearly as elevated as in the first weeks after starting the threatment

mk-677 can be taken longterm even tho not recommended because of the possible insulin resistance

Side Effects of mk-677

1. Possible Insulin resistance -> can be medigated through berberine and cycling + not taking dumb doses + having a look on your diet
2. Bloating caused by the increased water retention -> can be bettered by low sodium intake and high water intake
3. slight prolactin increase -> only sight not really relevant enough to be actually harmful
4. increased appetite through the ghrelin stimulation -> can be medigated a bit through taking it before going to sleep
5. Musle and joint pain ->( rare and generally mild )
6. Anecdotic but not study proven possible short term insomnia after stopping to take mk-677 -> not proven by science only anecdotic

So why is mk-677 so hated on here when it literally has postive effects on muscle mass recovery bone density, mineralization and bone volume
while having slight side effects which can be medigated if u dont act like a moron
this thread was high effort so rep it

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure - PubMed

Obesity is associated with blunted GH secretion, unfavorable body composition, and increased cardiovascular mortality. The objective of this study was to investigate the effects of oral treatment with the GH secretagogue MK-677 on GH secretion and body composition in otherwise healthy obese...

pubmed.ncbi.nlm.nih.gov

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial - PMC

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the ...

pmc.ncbi.nlm.nih.gov

Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males - PMC

Male hypogonadism is an increasingly prevalent clinical condition that affects patients’ quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold standard ...

pmc.ncbi.nlm.nih.gov

Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects - PubMed

Aging is associated with declining activity of the GH axis, possibly contributing to adverse body composition changes and increased incidence of cardiovascular disease. The stimulatory effects on the GH-insulin-like growth factor I (IGF-I) axis of orally administered MK-677, a GH-releasing...

pubmed.ncbi.nlm.nih.gov

MK-6777777777777777777 67777777777777 6 fucking 7 niggas

only lazycels who cant inject take mk netherless good thread

 

[HighIQ ubermensch]