Is High ALT levels serious in Liver?

[vitaminD3]

I tried to get Isotretinoin today but my dermatologist said my ALT enzyme in my liver was a bit higher than normal levels. I stopped taking meds (things I normally take) like a week before getting the blood test and I don’t understand if it spiked just before the test or not. Is my derm fucking with me?

 

[Lux]

I did accutane for 9 months & dk even what that enzyme is. As long as you're LDL's good you should be fine I think

 

[neithernorwood]

Could be https://en.wikipedia.org/wiki/Gilbert's_syndrome#:~:text=Gilbert's syndrome (GS) is a,, weakness, and abdominal pain.

i had elevated liver measurements in my blood tests.

just dont drink alcohol or take a lot of supplements while on accutane; you should be ok.

i'd say find a laxxer derm, mine was like: itll be fine

 

[Stare]

High ALT indicates acute liver damage.
There are many different things that can cause liver damage, meds are one of those.

 

[vitaminD3]

Could be https://en.wikipedia.org/wiki/Gilbert's_syndrome#:~:text=Gilbert's syndrome (GS) is a,, weakness, and abdominal pain.

i had elevated liver measurements in my blood test

just dont drink alcohol or take a lot of supplements while on accutane; you should be ok.

i'd say find a laxxer derm, mine was like: itll be fine

She’s making me see a liver specialist doctor then a immunologist after I fix my liver problem then see her. Wtf do I do I’ve spent like 500$ already for her shit topical creams that I did for 1 day but my skin got irritated as fuck

 

[neithernorwood]

search for other derm, read reviews, find someone who has reviews from ppl who had accutane with mild acne. shop around til you find a derm that gives you what you want.

 

[Stare]

Could be https://en.wikipedia.org/wiki/Gilbert's_syndrome#:~:text=Gilbert's syndrome (GS) is a,, weakness, and abdominal pain.

i had elevated liver measurements in my blood tests.

just dont drink alcohol or take a lot of supplements while on accutane; you should be ok.

i'd say find a laxxer derm, mine was like: itll be fine

JFL do you even know what Gilbert's disease is? The guy simply posted that he had high ALT and you assumed he had Gilbert's
There are countless causes of high ALT and you assumed he had Gilbert's just by the fact that he had high ALT without any symptom or exam to back it up

Holy fuck, go back to your cage greycel

 

[vitaminD3]

I did accutane for 9 months & dk even what that enzyme is. As long as you're LDL's good you should be fine I think

Did you have to take a blood test?

 

[vitaminD3]

JFL do you even know what Gilbert's disease is? The guy simply posted that he had high ALT and you assumed he had Gilbert's
There are countless causes of high ALT and you assumed he had Gilbert's just by the fact that he had high ALT without any symptom or exam to back it up

Holy fuck, go back to your cage greycel

I don’t have gilberts lmao

 

[Stare]

I don’t have gilberts lmao

I know that you don't

 

[vitaminD3]

I know that you don't

My ALT level is 34 is that too high for Accutane?

 

[Stare]

My ALT level is 34 is that too high for Accutane?

34 is within normal levels here (idk if they use different methods in different countries but here 34 is normal)
But if you dermatologist said you should not take it then you should listen to him

 

[vitaminD3]

34 is within normal levels here (idk if they use different methods in different countries but here 34 is normal)
But if you dermatologist said you should not take it then you should listen to him

Male normal levels is up to 40UL
I’m 34UL
I don’t understand how that’s too high
Unit of measurements in my derm is 5-30 that’s like a woman’s range

 

[Lux]

Did you have to take a blood test?

yeah

 

[Stare]

Male normal levels is up to 40UL
I’m 34UL
I don’t understand how that’s too high
Unit of measurements in my derm is 5-30 that’s like a woman’s range

Accutane is a really rough drug, it changes hormones all over the body and can damage the liver.
It's wise to follow what your derma said, after all he has a lot of experience with it.

Your ALT levels are probably alright but there might be another reason as to why he told you not to take it.

 

[vitaminD3]

Accutane is a really rough drug, it changes hormones all over the body and can damage the liver.
It's wise to follow what your derma said, after all he has a lot of experience with it.

Your ALT levels are probably alright but there might be another reason as to why he told you not to take it.

I’m just raging I’ve spent like almost 800$ on this shit every consultation is like 200$ and she talks for like 2 minutes.

 

[Stare]

I’m just raging I’ve spent like almost 800$ on this shit every consultation is like 200$ and she talks for like 2 minutes.

Fuck her
See a better derma

 

[Deleted member 4044]

How high was yours?

Mine was 52 last week (40 is the upper end of average range).

I'm trying to get it down

 

[Deleted member 4044]

Male normal levels is up to 40UL
I’m 34UL
I don’t understand how that’s too high
Unit of measurements in my derm is 5-30 that’s like a woman’s range

That's not high at all wtf

 

[vitaminD3]

That's not high at all wtf

That’s what im saying. She’s deadass making me pay for a liver specialist then a immunologist I’ve spent 800 just on consultation and topical cream in 2 weeks

 

[Deleted member 4044]

That’s what im saying. She’s deadass making me pay for a liver specialist then a immunologist I’ve spent 800 just on consultation and medicine.

She's a dumbcunt

See someone else

 

[Stare]

That’s what im saying. She’s deadass making me pay for a liver specialist then a immunologist I’ve spent 800 just on consultation and topical cream in 2 weeks

Don't go to any of these
See another derma instead

 

[vitaminD3]

Don't go to any of these
See another derma instead

Should I go to the liver specialist in case? I’ve got anxiety problems from relatives not giving a shit about medical problems and getting fucked by it and I can’t stop thinking about it

 

[Stare]

Should I go to the liver specialist in case? I’ve got anxiety problems from relatives not giving a shit about medical problems and getting fucked by it and I can’t stop thinking about it

Nah, you shouldn't.
At first I thought there might have been something that made she worried about you but now that I read the story I am 100% sure she is just trying to milk your money even more.
Your ALT is normal and you shouldn't worry too much about accutane but if you want to be extra safe then go see another derma.

 

[Deleted member 2095]

Accutane is a really rough drug, it changes hormones all over the body and can damage the liver.
It's wise to follow what your derma said, after all he has a lot of experience with it.

Your ALT levels are probably alright but there might be another reason as to why he told you not to take it.

Accutane doesn’t affect hormones

 

[Stare]

Accutane doesn’t affect hormones

BRAINLET COPE

The effect of different doses of isotretinoin on pituitary hormones - PubMed

ISO affects pituitary hormones at all of these three doses. The differences in pituitary hormones are more pronounced in high-dose treatment. The weakest effect was observed in the intermittent-dose group. Choosing lower doses of ISO may decrease side effects, however the effectiveness of the...

pubmed.ncbi.nlm.nih.gov

 

[Deleted member 2095]

BRAINLET COPE

The effect of different doses of isotretinoin on pituitary hormones - PubMed

ISO affects pituitary hormones at all of these three doses. The differences in pituitary hormones are more pronounced in high-dose treatment. The weakest effect was observed in the intermittent-dose group. Choosing lower doses of ISO may decrease side effects, however the effectiveness of the...

pubmed.ncbi.nlm.nih.gov

Not replicated by other studies. Peer Review needed

 

[Stare]

Not replicated by other studies. Peer Review needed

Then post studies that claim it didn't lower pituitary hormones

 

[Deleted member 2095]

Then post studies that claim it didn't lower pituitary hormones

Evaluation of hirsutism and hormonal parameters in acne vulgaris patients treated with isotretinoin - PubMed

In our study, it could not be revealed that isotretinoin has a significant effect on pituitary, adrenal hormones and insulin resistance. We found that 3 months of isotretinoin treatment caused an increase in menstrual irregularity and FG hirsutism score.

pubmed.ncbi.nlm.nih.gov

The effect of systemic isotretinoin on male fertility - PubMed

Systemic isotretinoin has a positive effect on male fertility. Since the hormone levels did not change significantly, this positive effect of isotretinoin is not via the hypothalamic-pituitary-gonadal axis but can be due to its regenerative and proliferative effects on the testes.

pubmed.ncbi.nlm.nih.gov

 

[Deleted member 2095]

Then post studies that claim it didn't lower pituitary hormones

Do acne treatments affect insulin-like growth factor-1 serum levels? A clinical and laboratory study on patients with acne vulgaris - PubMed

Acne is a chronic inflammatory disease affecting sebaceous gland follicles. Lately, acne has considered an insulin-like growth factor-1 (IGF-1) mediated disease. Recent research demonstrated that IGF-1 levels decrease after 3 months of isotretinoin. The purpose of our study is evaluating the...

pubmed.ncbi.nlm.nih.gov

 

[Stare]

Evaluation of hirsutism and hormonal parameters in acne vulgaris patients treated with isotretinoin - PubMed

In our study, it could not be revealed that isotretinoin has a significant effect on pituitary, adrenal hormones and insulin resistance. We found that 3 months of isotretinoin treatment caused an increase in menstrual irregularity and FG hirsutism score.

pubmed.ncbi.nlm.nih.gov

The effect of systemic isotretinoin on male fertility - PubMed

Systemic isotretinoin has a positive effect on male fertility. Since the hormone levels did not change significantly, this positive effect of isotretinoin is not via the hypothalamic-pituitary-gonadal axis but can be due to its regenerative and proliferative effects on the testes.

pubmed.ncbi.nlm.nih.gov

First 2 studies measured sexual hormones, not pituitary hormones

Do acne treatments affect insulin-like growth factor-1 serum levels? A clinical and laboratory study on patients with acne vulgaris - PubMed

Acne is a chronic inflammatory disease affecting sebaceous gland follicles. Lately, acne has considered an insulin-like growth factor-1 (IGF-1) mediated disease. Recent research demonstrated that IGF-1 levels decrease after 3 months of isotretinoin. The purpose of our study is evaluating the...

pubmed.ncbi.nlm.nih.gov

This study doesn't say what they took unless you pay for it, there is nothing in the abstract saying that they took accutane. In the end they say that they tried topical and systemic treatments.

 

[Deleted member 2095]

First 2 studies measured sexual hormones, not pituitary hormones

This study doesn't say what they took unless you pay for it, there is nothing in the abstract saying that they took accutane. In the end they say that they tried topical and systemic treatments.

Bitch u know about sci-hub?

 

[Stare]

Bitch u know about sci-hub?

Yes

 

[vitaminD3]

yeah

can you PM me privately? i cant message you
(unrelated to thread)

 

[Deleted member 2095]

Yes

No you don’t. If you did, you would see that they used Isotretinoin

 

[Stare]

No you don’t. If you did, you would see that they used Isotretinoin

Cope

JFL at you for ignoring all the evidence suggesting that accutane fucks up pituitary hormones just because you found an underground study that said it doesn't while there are countless studies and dermatology books saying it does.

You didn't even read 2 out of the 3 articles you posted.

JFL this forum is full of brainlets

 

[Deleted member 2095]

Cope

JFL at you for ignoring all the evidence suggesting that accutane fucks up pituitary hormones just because you found an underground study that said it doesn't while there are countless studies and dermatology books saying it does.

You didn't even read 2 out of the 3 articles you posted.

JFL this forum is full of brainlets

There are only two studies confirming effects on pituitary hormones which are both from the same dubious Turkish researchers

JuSt acknowledge that there is contradicting research on this field. Also lol @ "underground study" seriously?