Is it true that low levels of estrogen can reduce potential height and bone mass?

[olkn2890]

I’m currently taking 1 mg of anastrozole daily. When I asked an AI about this protocol, it warned of two critical risks:

1. Critically suppressed estrogen (likely <15 pg/mL), blocking osteoblast differentiation → impaired bone mineralization and accelerated bone loss.
2. Premature growth plate closure (6-12 months earlier than natural timing) – not during use, but upon discontinuation due to estrogen rebound.

The AI advised immediate tapering to avoid irreversible damage.

I countered with a study where a 14-year-old took the same dose + exogenous HGH for 2 years, achieving +12.5 cm height. The AI acknowledged this but emphasized:
→ Success required supraphysiological IGF-1 (500-600 ng/mL) from HGH to bypass estrogen-dependent osteoblast pathways
→ Without equivalent IGF-1 elevation, bone formation would be compromised

We compromised on a modified protocol:
→ Reduce to 0.5 mg/day
→ Add Ipamorelin if my IGF-1 is <300-400 ng/mL
→ Strictly monitor E2 (target: 20-35 pg/mL) and IGF-1

Questions for the community:
1. Is the AI’s claim about osteoblast differentiation failure at low E2 (<20 pg/mL) valid and what to do about it?
2. How real is the rebound-triggered growth plate closure risk?
3. Would this protocol genuinely maximize height with moderate risks?
4. What’s the best protocol to maximise height in your opinion?

 

[expert]

take 5mg of arimidex daily for increased height gains, if your estrogen crashes, dont mind about it
Be a real man.

 

[olkn2890]

@anzohhh you replied to my previous thread and i’d like to hear your opinion

 

[olkn2890]

up

 

[olkn2890]

bump

 

[bonelesscoward]

take 5mg of arimidex daily for increased height gains, if your estrogen crashes, dont mind about it
Be a real man.

Shut the fuck up nigger

 

[olkn2890]

Shut the fuck up nigger

maybe you know something about it?

 

[HandsomeHustler]

Do you rely on ai for everything? Do you have a brain of your own?

 

[olkn2890]

Do you rely on ai for everything? Do you have a brain of your own?

Not for everything, but it’s the easiest way to get pretty unbiased information and you can also ask it to explain if you don’t understand, so why not?

 

[Dave1]

1. Critically suppressed estrogen (likely <15 pg/mL), blocking osteoblast differentiation → impaired bone mineralization and accelerated bone loss.

get bloodwork and keep it 15 - 20. if u were on hgh 10 - 15 would be preferred since hgh would counteract the bone minersalisation loss.

2. Premature growth plate closure (6-12 months earlier than natural timing) – not during use, but upon discontinuation due to estrogen rebound.

thats why u use a suicidal inhibitor like aromasin

 

[3pider]

take 5mg of arimidex daily for increased height gains, if your estrogen crashes, dont mind about it
Be a real man.

Yeah who gives a fuck about neuro protective hormones

 

[mirinturbolowinhib]

I’m currently taking 1 mg of anastrozole daily. When I asked an AI about this protocol, it warned of two critical risks:

1. Critically suppressed estrogen (likely <15 pg/mL), blocking osteoblast differentiation → impaired bone mineralization and accelerated bone loss.
2. Premature growth plate closure (6-12 months earlier than natural timing) – not during use, but upon discontinuation due to estrogen rebound.

The AI advised immediate tapering to avoid irreversible damage.

I countered with a study where a 14-year-old took the same dose + exogenous HGH for 2 years, achieving +12.5 cm height. The AI acknowledged this but emphasized:
→ Success required supraphysiological IGF-1 (500-600 ng/mL) from HGH to bypass estrogen-dependent osteoblast pathways
→ Without equivalent IGF-1 elevation, bone formation would be compromised

We compromised on a modified protocol:
→ Reduce to 0.5 mg/day
→ Add Ipamorelin if my IGF-1 is <300-400 ng/mL
→ Strictly monitor E2 (target: 20-35 pg/mL) and IGF-1

Questions for the community:
1. Is the AI’s claim about osteoblast differentiation failure at low E2 (<20 pg/mL) valid and what to do about it?
2. How real is the rebound-triggered growth plate closure risk?
3. Would this protocol genuinely maximize height with moderate risks?
4. What’s the best protocol to maximise height in your opinion?

No bc it estrogen is the one that closes growth plates if estrogen is chronically low growth plates will be open longer look at for example people with estrogen deficiency they're height increases and growthplates are open up to 25 years old and estrogen doesnt increase bonemass it does help in bone density through