Isotret vs tret for Collagen

[spermium]

Apparently isotretinoin boosts collagen in a similar fashion to tretinoin, but I couldn't find any info comparing the two

Do we even know at all ? Barring cope side effects which one offers the strongest increase in collagen production?

 

[piec]

tret is irritating and annoying to apply, also weaker against acne

thats the difference between the 2

 

[Jonas2k7]

Isotretinoin better, should also fix acne on overall body (so if back acne = no more back acne )

 

[spermium]

tret is irritating and annoying to apply, also weaker against acne

thats the difference between the 2

What about collagen production?

 

[spermium]

Isotretinoin better, should also fix acne on overall body (so if back acne = no more back acne )

Isotretinoin would increase collagen all over the body, but can it do that to the extent tretinoin does ?

 

[piec]

What about collagen production?

its the same drug nigga

 

[spermium]

its the same drug nigga

They aren't niggus, they're structurally different and do different stuff in the body

 

[piec]

They aren't niggus, they're structurally different and do different stuff in the body

oh my fucking god nigger no shit since one is designed to take orally and one topically

to make it simple for you: yes they will have more or less same effect on your collagen production

 

[Thebuffdon]

Accutane defo since it has the fastest turnover rate

Tret is really overhyped here in normie mainstream it’s known to not effect like 30-40% of users

Tazarotene is way better in terms of potency and efficacy

 

[N1666]

They aren't niggus, they're structurally different and do different stuff in the body

They both increase collagen, just in different ways (due to binding affinity to different retinoid receptors). In theory tretinoin should be better for collagen boosting as it increases cell turnover and collagen production, but it rapes your skin at the same time. This study suggests that isotret is effective for the production of collagen and more convenient than topical retinoids like tret.

Oral isotretinoin in photoaging: objective histological evidence of efficacy and durability

Abstract BACKGROUND: The off-label use of oral isotretinoin in photoaging is a therapeutic tool...

www.scielo.br

 

[spermium]

oh my fucking god nigger no shit since one is designed to take orally and one topically

Nigger stop nigging they're two different compounds
Oral tretinoin is different from oral isotretinoin and topical tretinoin is different from topical isotretinoin

They're not the nigging same nigga

 

[spermium]

Accutane defo since it has the fastest turnover rate

Tret is really overhyped here in normie mainstream it’s known to not effect like 30-40% of users

Tazarotene is way better in terms of potency and efficacy

Yeah I switched to taz, wonder if isotretinoin is still better than that too

 

[spermium]

They both increase collagen, just in different ways (due to binding affinity to different retinoid receptors). In theory tretinoin should be better for collagen boosting as it increases cell turnover and collagen production, but it rapes your skin at the same time. This study suggests that isotret is effective for the production of collagen and more convenient than topical retinoids like tret.

View attachment 3287172

Oral isotretinoin in photoaging: objective histological evidence of efficacy and durability

Abstract BACKGROUND: The off-label use of oral isotretinoin in photoaging is a therapeutic tool...

www.scielo.br

So stacking them would be ideal ?

 

[piec]

Nigger stop nigging they're two different compounds
Oral tretinoin is different from oral isotretinoin and topical tretinoin is different from topical isotretinoin

They're not the nigging same nigga

just read the nigger above

 

[Thebuffdon]

Yeah I switched to taz, wonder if isotretinoin is still better than that too

For turnover yes it is, it’s the most effective

However too many sides and less effective for anti ageing than taz

Taz gives insane collagen and anti ageing but not as good for acne

 

[spermium]

For turnover yes it is, it’s the most effective

However too many sides and less effective for anti ageing than taz

Taz gives insane collagen and anti ageing but not as good for acne

But wouldn't a higher turnover rate mean more skin renewal so more collagen elastin and all of that ?

 

[Thebuffdon]

But wouldn't a higher turnover rate mean more skin renewal so more collagen elastin and all of that ?

Yeh it’s On a similar level but taz still mogs for anti ageing

If you run isotret long term the sides would probably be worse than taz or tret

Just cuz of the higher turnover rate

 

[N1666]

So stacking them would be ideal ?

If your goal is to boost collagen, then no. Personally I mainly use tazarotene (and a few other things) because most studies I read showed tazarotene to be effective for my needs.

This is a good read and will help you understand more

Is Tazarotene Better Than Tretinoin? (For Aging & Acne)

Tazarotene, the active ingredient in Tazorac and Arzalo, may produce results faster than tretinoin for anti-aging, but long-term use leads to similar results.

lifepathdoc.com