Sachlichkeit
Bronze
- Joined
- May 11, 2025
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K lads
State of the cycle address
We have plateaued through poor diet, stuck at 170. most of cycle has just been upper chest and little delt gains
Completely ignoring statins/cholesterol. Gear modulates bad cholesterol in negative fashion while doing the opposite for good cholesterol, arterial plaque buildup then quietly kills the user. stroke, heart attack, clog arteries, etcetera. SO,
10MG Rosuvastatin, 10MG EZETIMBE, 2400MG KYOLIC, 4g Icosapent Ethyl AM/PM SPLIT. This may not even be necessary because of how early I am into cycle. I am in dire need of a panel. Also 500ml phlebotomy, probably self-imposed.
I plan on splitting the IGF-1 axis next cycle ~30 days out, between exogenous HGH, MK (appetite stim) & CJC+DAC in order to keep some portion of endogenous pulsatility. IPAMORELIN is too much work and poor in practice. obv tren E for IGF-1 local transcription as well
INSULIN
beside IGF-1 is insulin, the permissive window for both muscle and bone growth. I have already touched on this, but if you really wanted to get aesthetically huge, just pin insulin, (which people do,) I am pulling away and getting too old for LM, my priorities are shifting. I won't say that studying, sourcing, and pinning insulin isn't worth it for gains, (because as far as I can tell, it actually is. Yes, insulin is probably the biggest lever in growth besides IGF1,) but I am pretty much past my research phase and more into application and optimization.
MILK & SUGAR, cane sugar (not HFC's high fructose corn syrup) are my preferred ways of targeting insulin. Milk disproportionately spikes insulin relative to its sugar content, provides calcium, steady source of calories, and high quality protein. Sugar is pure carbs, glycemically close to white rice (meaning ez to digest,) and also spikes insulin. Also cardio is still more effective for insulin resistance than any drug.
TAZMETOSTAT AND VORINOSTAT
Vorinostat, which all of u already know about is an epigenetic modulator that turns up the volume on androgen receptor transcription. somebody on vorinostat will get more effects from steroids from somebody not.
Not discussed is DNA damage and the poor application window. I believe the chromatin around DNA re-tightens after 48 hours, peak saturation occurs after a week of use and persists for 2 weeks (I believe.) So 1 week on 2 weeks off right? nah. Well yes, but in order to reverse damage and clean up DNA you are looking at like 8 Weeks of no HDACI. Vorinostat just kills cells. Its not a gene drug that loosens chromatin allowing for androgenic/estrogenic expression, its a chemotherapy drug. Lmao. Literally HALF of the patients in the studies developed some sort of cell death related problem. Typically low red blood cell count OR low platelets. This is less of an issue as standard sub therapeutic dose is 25-50mg but still something to take into account.
Tazmetostat is a different animal, cleaner, but works completely different. Vstat enhances already present growth programs tazmetostat turns on some of the ones present in puberty.
If you use it, will have to be 800MG split BID (2x,) day so 400mg AM PM. Its significantly safer than Vstat, though there are no anecdotal testimonies I can lean on for what a taz cycle would actually produce. With HDACi, there are, (picrel.) Though you have to run tazmetostat constantly and the lowest dose is the oncological one. A subtherapeutic cycle wont do anything. Needs to be 800mg ed (maybe for the entire cycle) as de-repression of these developmental programs take time.
Fasting and GLP ags.
Metformin, old go-to for insulin control, modulates IGF-1 expression while disproportionately effecting insulin. Better than that for insulin are the fat people drugs, (ozempic, reta, etc.) Which are the new standard for insulin control. obv im writing about this because use of exo GH, secretagogues, & sugar. Reta, which is in stage 3 trials, probably soon to be passed as new fat people drug seems to be the best because it spares muscle more than the others. Why do we use reta?
FASTING. If u stop eating, the body shifts away from growth AND maintenance mode into repair mode. Cell autophagy, cell recycling, is upregulated, blablabla.
Insulin sensitivity, renews stem cells, recycles retarded cells and mitochondria, blood pressure drops, good cholesterol rises, yadayadaya. Its good. Don't fast after coming off of vstat though, gene PCT is different animal, supplemental re-methylation is needed most likely I wrote about this a long time ago.
So we are using reta to kickstart a week long fast in the near future maybe inbetween cycles.
Edit I forgot to write about 19nor damage
Deca and Tren damage the fertility axis. Coming off of T you only need a PCT and HCG during cycle, 19nors negatively modulate dopamine through prolactin, which can also give u man tits. and flatten ur mood because dopamine
For T? HCG. For 19nors
HCG
HMG (second half of fertility axis)
Cabergoline (Dopamine agonist.) Dopamine is opposite of prolactin
Full recovery is longer than standard test steroid cycle I believe.
70-90% of men regained sperm using HCG and FSH post 19nor. that is actually low. the odds you are infertile from standard gear use i.e test is like near zero. if 10% of steroid users became infertile it would be a serious problem for many and scare them away.
The best way to fix this is to catch it early by running HCG and HMG during cycle so you never reach azoospermia (ZERO SPERM.)
o7
State of the cycle address
We have plateaued through poor diet, stuck at 170. most of cycle has just been upper chest and little delt gains
Completely ignoring statins/cholesterol. Gear modulates bad cholesterol in negative fashion while doing the opposite for good cholesterol, arterial plaque buildup then quietly kills the user. stroke, heart attack, clog arteries, etcetera. SO,
10MG Rosuvastatin, 10MG EZETIMBE, 2400MG KYOLIC, 4g Icosapent Ethyl AM/PM SPLIT. This may not even be necessary because of how early I am into cycle. I am in dire need of a panel. Also 500ml phlebotomy, probably self-imposed.
I plan on splitting the IGF-1 axis next cycle ~30 days out, between exogenous HGH, MK (appetite stim) & CJC+DAC in order to keep some portion of endogenous pulsatility. IPAMORELIN is too much work and poor in practice. obv tren E for IGF-1 local transcription as well
INSULIN
beside IGF-1 is insulin, the permissive window for both muscle and bone growth. I have already touched on this, but if you really wanted to get aesthetically huge, just pin insulin, (which people do,) I am pulling away and getting too old for LM, my priorities are shifting. I won't say that studying, sourcing, and pinning insulin isn't worth it for gains, (because as far as I can tell, it actually is. Yes, insulin is probably the biggest lever in growth besides IGF1,) but I am pretty much past my research phase and more into application and optimization.
MILK & SUGAR, cane sugar (not HFC's high fructose corn syrup) are my preferred ways of targeting insulin. Milk disproportionately spikes insulin relative to its sugar content, provides calcium, steady source of calories, and high quality protein. Sugar is pure carbs, glycemically close to white rice (meaning ez to digest,) and also spikes insulin. Also cardio is still more effective for insulin resistance than any drug.
TAZMETOSTAT AND VORINOSTAT
Vorinostat, which all of u already know about is an epigenetic modulator that turns up the volume on androgen receptor transcription. somebody on vorinostat will get more effects from steroids from somebody not.
Not discussed is DNA damage and the poor application window. I believe the chromatin around DNA re-tightens after 48 hours, peak saturation occurs after a week of use and persists for 2 weeks (I believe.) So 1 week on 2 weeks off right? nah. Well yes, but in order to reverse damage and clean up DNA you are looking at like 8 Weeks of no HDACI. Vorinostat just kills cells. Its not a gene drug that loosens chromatin allowing for androgenic/estrogenic expression, its a chemotherapy drug. Lmao. Literally HALF of the patients in the studies developed some sort of cell death related problem. Typically low red blood cell count OR low platelets. This is less of an issue as standard sub therapeutic dose is 25-50mg but still something to take into account.
Tazmetostat is a different animal, cleaner, but works completely different. Vstat enhances already present growth programs tazmetostat turns on some of the ones present in puberty.
If you use it, will have to be 800MG split BID (2x,) day so 400mg AM PM. Its significantly safer than Vstat, though there are no anecdotal testimonies I can lean on for what a taz cycle would actually produce. With HDACi, there are, (picrel.) Though you have to run tazmetostat constantly and the lowest dose is the oncological one. A subtherapeutic cycle wont do anything. Needs to be 800mg ed (maybe for the entire cycle) as de-repression of these developmental programs take time.
Fasting and GLP ags.
Metformin, old go-to for insulin control, modulates IGF-1 expression while disproportionately effecting insulin. Better than that for insulin are the fat people drugs, (ozempic, reta, etc.) Which are the new standard for insulin control. obv im writing about this because use of exo GH, secretagogues, & sugar. Reta, which is in stage 3 trials, probably soon to be passed as new fat people drug seems to be the best because it spares muscle more than the others. Why do we use reta?
FASTING. If u stop eating, the body shifts away from growth AND maintenance mode into repair mode. Cell autophagy, cell recycling, is upregulated, blablabla.
Insulin sensitivity, renews stem cells, recycles retarded cells and mitochondria, blood pressure drops, good cholesterol rises, yadayadaya. Its good. Don't fast after coming off of vstat though, gene PCT is different animal, supplemental re-methylation is needed most likely I wrote about this a long time ago.
So we are using reta to kickstart a week long fast in the near future maybe inbetween cycles.
Edit I forgot to write about 19nor damage
Deca and Tren damage the fertility axis. Coming off of T you only need a PCT and HCG during cycle, 19nors negatively modulate dopamine through prolactin, which can also give u man tits. and flatten ur mood because dopamine
For T? HCG. For 19nors
HCG
HMG (second half of fertility axis)
Cabergoline (Dopamine agonist.) Dopamine is opposite of prolactin
Full recovery is longer than standard test steroid cycle I believe.
70-90% of men regained sperm using HCG and FSH post 19nor. that is actually low. the odds you are infertile from standard gear use i.e test is like near zero. if 10% of steroid users became infertile it would be a serious problem for many and scare them away.
The best way to fix this is to catch it early by running HCG and HMG during cycle so you never reach azoospermia (ZERO SPERM.)
o7
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