🧬 [MEGATHREAD] Genetics of Appearance: How Traits Are Inherited

Coffeebackwards

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Introduction:

Human appearance including facial structure, skin tone, eye color, hair texture, height, and hormone driven features is controlled by complex genetic interactions. Understanding how traits are inherited helps explain why children resemble their parents, and why some combinations tend to produce strong aesthetic traits.


1. Chromosomes and Inheritance Basics:
Humans have 23 chromosome pairs: 22 autosomes + 1 sex chromosome pair (XX or XY).

Each chromosome contains thousands of genes, coding for proteins that influence appearance and hormone regulation.

Autosomal inheritance: Most facial and body traits are on autosomes, meaning children inherit a mix from both parents.

Sex linked inheritance: Some hormonal and secondary sexual traits are influenced by X/Y chromosomes.

2. Dominant, Recessive, and Polygenic Traits:
Dominant traits require only one allele to express, recessive traits require two.

Many aesthetic traits are polygenic, influenced by hundreds of genes interacting.

Examples: jawline strength, midface projection, eye shape, height.

Result: Even if both parents have strong features, a child may or may not inherit the combination in the same way.

3. Facial Structure and Key Genes:
Jawline & Mandible: FGFR, MSX1, RUNX2

Cheekbone prominence / zygomatic projection: COL1A1, COL1A2, IGF1

Nose shape & midface projection: TBX15, PAX3

Eye spacing & shape: PAX6, BMP4

These genes interact in complex ways, no single gene guarantees a perfect jaw or cheekbone.

4. Eye Color Inheritance:
Eye color is polygenic, with OCA2 and HERC2 being primary genes. Other genes (TYR, SLC24A4, SLC45A2) modify green, hazel, and blue shades.

Brown is generally dominant, green is intermediate, blue is recessive.


Example: Mother brown eyes (B), Father green eyes (G)

Mother alleleFather allele Likely outcome

B G Brown eyes (B usually dominates)
B G Brown eyes
B G Brown/green mix possible with polygenic modifiers

Siblings can have different eye colors due to random allele assortment.

Eye color is influenced by multiple minor genes, so slight variations (hazel, lighter brown, green) are possible.

5. Height Inheritance:
Height is highly polygenic, controlled by hundreds of genes (FGFR3, HMGA2, GH1, IGF1).

Rough estimate: children tend to be within ±10 cm of mid-parental height.

Mid-parental height formula:

Boys: (Father + Mother + 13 cm and then divide it by 2, example: father = 185 cm Mother = 160 cm that's 345 cm + 13 cm = 358 ÷ 2 = 179cm meaning that COULD be the final height of the boy but it's not 100% accurate as there are other factors Influencing this as well.)

Girls: (Father + Mother − 13 cm) ÷ 2


Environmental modifiers:

Nutrition

Sleep quality (GH secretion)

Chronic illness or stress

Physical activity

Key point: Polygenic variation + environment > children may deviate from predicted height.

6. Hormonal Influence & Sex Chromosomes:
Testosterone, estrogen, and growth hormone levels are partially genetically determined.

Genes on X/Y chromosomes regulate hormone receptors and enzyme efficiency.

Implications:

Muscle mass

Fat distribution

Facial bone projection

Secondary sexual characteristics

7. Epigenetics: The Modifier Layer:
Environmental factors can turn genes on/off without changing DNA.

Important factors:

Nutrition

Stress

Sleep

Exposure to toxins


Influences: collagen, bone density, fat distribution, facial symmetry.

8. Polygenic Probabilities for Aesthetic Traits:
High aesthetic potential often comes from complementary parental traits:

Strong jawline + midface projection + good skin tone


Random assortment creates variability, siblings can differ widely.

Environmental support during growth maximizes genetic potential.

9. Takeaways for Looksmaxxing Genetics:
Genetics sets the baseline potential for facial and body traits.

Combining complementary features increases probability of aesthetic offspring.

Lifestyle factors strongly influence gene expression (nutrition, posture, hormones).

Traits like eye color and height are probabilistic, not guaranteed.

Disclaimer:

This post is educational/research focused.
It does not provide medical advice, suggest genetic modification, or endorse trying to design children. Genetics are probabilistic and highly complex.
 
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Introduction:

Human appearance including facial structure, skin tone, eye color, hair texture, height, and hormone driven features is controlled by complex genetic interactions. Understanding how traits are inherited helps explain why children resemble their parents, and why some combinations tend to produce strong aesthetic traits.


1. Chromosomes and Inheritance Basics:

Humans have 23 chromosome pairs: 22 autosomes + 1 sex chromosome pair (XX or XY).

Each chromosome contains thousands of genes, coding for proteins that influence appearance and hormone regulation.

Autosomal inheritance: Most facial and body traits are on autosomes, meaning children inherit a mix from both parents.

Sex linked inheritance: Some hormonal and secondary sexual traits are influenced by X/Y chromosomes.


2. Dominant, Recessive, and Polygenic Traits:

Dominant traits require only one allele to express, recessive traits require two.

Many aesthetic traits are polygenic, influenced by hundreds of genes interacting.

Examples: jawline strength, midface projection, eye shape, height.

Result: Even if both parents have strong features, a child may or may not inherit the combination in the same way.


3. Facial Structure and Key Genes:

Jawline & Mandible: FGFR, MSX1, RUNX2

Cheekbone prominence / zygomatic projection: COL1A1, COL1A2, IGF1

Nose shape & midface projection: TBX15, PAX3

Eye spacing & shape: PAX6, BMP4

These genes interact in complex ways, no single gene guarantees a perfect jaw or cheekbone.


4. Eye Color Inheritance:

Eye color is polygenic, with OCA2 and HERC2 being primary genes. Other genes (TYR, SLC24A4, SLC45A2) modify green, hazel, and blue shades.

Brown is generally dominant, green is intermediate, blue is recessive.


Example: Mother brown eyes (B), Father green eyes (G)

Mother alleleFather allele Likely outcome

B G Brown eyes (B usually dominates)
B G Brown eyes
B G Brown/green mix possible with polygenic modifiers

Siblings can have different eye colors due to random allele assortment.

Eye color is influenced by multiple minor genes, so slight variations (hazel, lighter brown, green) are possible.


5. Height Inheritance:

Height is highly polygenic, controlled by hundreds of genes (FGFR3, HMGA2, GH1, IGF1).

Rough estimate: children tend to be within ±10 cm of mid-parental height.

Mid-parental height formula:

Boys: (Father + Mother + 13 cm and then divide it by 2, example: father = 185 cm Mother = 160 cm that's 345 cm + 13 cm = 358 ÷ 2 = 179cm meaning that COULD be the final height of the boy but it's not 100% accurate as there are other factors Influencing this as well.)

Girls: (Father + Mother − 13 cm) ÷ 2


Environmental modifiers:

Nutrition

Sleep quality (GH secretion)

Chronic illness or stress

Physical activity

Key point: Polygenic variation + environment > children may deviate from predicted height.


6. Hormonal Influence & Sex Chromosomes:

Testosterone, estrogen, and growth hormone levels are partially genetically determined.

Genes on X/Y chromosomes regulate hormone receptors and enzyme efficiency.

Implications:

Muscle mass

Fat distribution

Facial bone projection

Secondary sexual characteristics


7. Epigenetics: The Modifier Layer:

Environmental factors can turn genes on/off without changing DNA.

Important factors:

Nutrition

Stress

Sleep

Exposure to toxins


Influences: collagen, bone density, fat distribution, facial symmetry.


8. Polygenic Probabilities for Aesthetic Traits:

High aesthetic potential often comes from complementary parental traits:

Strong jawline + midface projection + good skin tone


Random assortment creates variability, siblings can differ widely.

Environmental support during growth maximizes genetic potential.


9. Takeaways for Looksmaxxing Genetics:

Genetics sets the baseline potential for facial and body traits.

Combining complementary features increases probability of aesthetic offspring.

Lifestyle factors strongly influence gene expression (nutrition, posture, hormones).

Traits like eye color and height are probabilistic, not guaranteed.


Disclaimer:

This post is educational/research focused.
It does not provide medical advice, suggest genetic modification, or endorse trying to design children. Genetics are probabilistic and highly complex.
I did not mean to post it now, still unedited
 
Introduction:

Human appearance including facial structure, skin tone, eye color, hair texture, height, and hormone driven features is controlled by complex genetic interactions. Understanding how traits are inherited helps explain why children resemble their parents, and why some combinations tend to produce strong aesthetic traits.


1. Chromosomes and Inheritance Basics:

Humans have 23 chromosome pairs: 22 autosomes + 1 sex chromosome pair (XX or XY).

Each chromosome contains thousands of genes, coding for proteins that influence appearance and hormone regulation.

Autosomal inheritance: Most facial and body traits are on autosomes, meaning children inherit a mix from both parents.

Sex linked inheritance: Some hormonal and secondary sexual traits are influenced by X/Y chromosomes.


2. Dominant, Recessive, and Polygenic Traits:

Dominant traits require only one allele to express, recessive traits require two.

Many aesthetic traits are polygenic, influenced by hundreds of genes interacting.

Examples: jawline strength, midface projection, eye shape, height.

Result: Even if both parents have strong features, a child may or may not inherit the combination in the same way.


3. Facial Structure and Key Genes:

Jawline & Mandible: FGFR, MSX1, RUNX2

Cheekbone prominence / zygomatic projection: COL1A1, COL1A2, IGF1

Nose shape & midface projection: TBX15, PAX3

Eye spacing & shape: PAX6, BMP4

These genes interact in complex ways, no single gene guarantees a perfect jaw or cheekbone.


4. Eye Color Inheritance:

Eye color is polygenic, with OCA2 and HERC2 being primary genes. Other genes (TYR, SLC24A4, SLC45A2) modify green, hazel, and blue shades.

Brown is generally dominant, green is intermediate, blue is recessive.


Example: Mother brown eyes (B), Father green eyes (G)

Mother alleleFather allele Likely outcome

B G Brown eyes (B usually dominates)
B G Brown eyes
B G Brown/green mix possible with polygenic modifiers

Siblings can have different eye colors due to random allele assortment.

Eye color is influenced by multiple minor genes, so slight variations (hazel, lighter brown, green) are possible.


5. Height Inheritance:

Height is highly polygenic, controlled by hundreds of genes (FGFR3, HMGA2, GH1, IGF1).

Rough estimate: children tend to be within ±10 cm of mid-parental height.

Mid-parental height formula:

Boys: (Father + Mother + 13 cm and then divide it by 2, example: father = 185 cm Mother = 160 cm that's 345 cm + 13 cm = 358 ÷ 2 = 179cm meaning that COULD be the final height of the boy but it's not 100% accurate as there are other factors Influencing this as well.)

Girls: (Father + Mother − 13 cm) ÷ 2


Environmental modifiers:

Nutrition

Sleep quality (GH secretion)

Chronic illness or stress

Physical activity

Key point: Polygenic variation + environment > children may deviate from predicted height.


6. Hormonal Influence & Sex Chromosomes:

Testosterone, estrogen, and growth hormone levels are partially genetically determined.

Genes on X/Y chromosomes regulate hormone receptors and enzyme efficiency.

Implications:

Muscle mass

Fat distribution

Facial bone projection

Secondary sexual characteristics


7. Epigenetics: The Modifier Layer:

Environmental factors can turn genes on/off without changing DNA.

Important factors:

Nutrition

Stress

Sleep

Exposure to toxins


Influences: collagen, bone density, fat distribution, facial symmetry.


8. Polygenic Probabilities for Aesthetic Traits:

High aesthetic potential often comes from complementary parental traits:

Strong jawline + midface projection + good skin tone


Random assortment creates variability, siblings can differ widely.

Environmental support during growth maximizes genetic potential.


9. Takeaways for Looksmaxxing Genetics:

Genetics sets the baseline potential for facial and body traits.

Combining complementary features increases probability of aesthetic offspring.

Lifestyle factors strongly influence gene expression (nutrition, posture, hormones).

Traits like eye color and height are probabilistic, not guaranteed.


Disclaimer:

This post is educational/research focused.
It does not provide medical advice, suggest genetic modification, or endorse trying to design children. Genetics are probabilistic and highly complex.
BOTB
 
  • +1
Reactions: Coffeebackwards
Introduction:

Human appearance including facial structure, skin tone, eye color, hair texture, height, and hormone driven features is controlled by complex genetic interactions. Understanding how traits are inherited helps explain why children resemble their parents, and why some combinations tend to produce strong aesthetic traits.


1. Chromosomes and Inheritance Basics:
Humans have 23 chromosome pairs: 22 autosomes + 1 sex chromosome pair (XX or XY).

Each chromosome contains thousands of genes, coding for proteins that influence appearance and hormone regulation.

Autosomal inheritance: Most facial and body traits are on autosomes, meaning children inherit a mix from both parents.

Sex linked inheritance: Some hormonal and secondary sexual traits are influenced by X/Y chromosomes.

2. Dominant, Recessive, and Polygenic Traits:
Dominant traits require only one allele to express, recessive traits require two.

Many aesthetic traits are polygenic, influenced by hundreds of genes interacting.

Examples: jawline strength, midface projection, eye shape, height.

Result: Even if both parents have strong features, a child may or may not inherit the combination in the same way.

3. Facial Structure and Key Genes:
Jawline & Mandible: FGFR, MSX1, RUNX2

Cheekbone prominence / zygomatic projection: COL1A1, COL1A2, IGF1

Nose shape & midface projection: TBX15, PAX3

Eye spacing & shape: PAX6, BMP4

These genes interact in complex ways, no single gene guarantees a perfect jaw or cheekbone.

4. Eye Color Inheritance:
Eye color is polygenic, with OCA2 and HERC2 being primary genes. Other genes (TYR, SLC24A4, SLC45A2) modify green, hazel, and blue shades.

Brown is generally dominant, green is intermediate, blue is recessive.


Example: Mother brown eyes (B), Father green eyes (G)

Mother alleleFather allele Likely outcome

B G Brown eyes (B usually dominates)
B G Brown eyes
B G Brown/green mix possible with polygenic modifiers

Siblings can have different eye colors due to random allele assortment.

Eye color is influenced by multiple minor genes, so slight variations (hazel, lighter brown, green) are possible.

5. Height Inheritance:
Height is highly polygenic, controlled by hundreds of genes (FGFR3, HMGA2, GH1, IGF1).

Rough estimate: children tend to be within ±10 cm of mid-parental height.

Mid-parental height formula:

Boys: (Father + Mother + 13 cm and then divide it by 2, example: father = 185 cm Mother = 160 cm that's 345 cm + 13 cm = 358 ÷ 2 = 179cm meaning that COULD be the final height of the boy but it's not 100% accurate as there are other factors Influencing this as well.)

Girls: (Father + Mother − 13 cm) ÷ 2


Environmental modifiers:

Nutrition

Sleep quality (GH secretion)

Chronic illness or stress

Physical activity

Key point: Polygenic variation + environment > children may deviate from predicted height.

6. Hormonal Influence & Sex Chromosomes:
Testosterone, estrogen, and growth hormone levels are partially genetically determined.

Genes on X/Y chromosomes regulate hormone receptors and enzyme efficiency.

Implications:

Muscle mass

Fat distribution

Facial bone projection

Secondary sexual characteristics

7. Epigenetics: The Modifier Layer:
Environmental factors can turn genes on/off without changing DNA.

Important factors:

Nutrition

Stress

Sleep

Exposure to toxins


Influences: collagen, bone density, fat distribution, facial symmetry.

8. Polygenic Probabilities for Aesthetic Traits:
High aesthetic potential often comes from complementary parental traits:

Strong jawline + midface projection + good skin tone


Random assortment creates variability, siblings can differ widely.

Environmental support during growth maximizes genetic potential.

9. Takeaways for Looksmaxxing Genetics:
Genetics sets the baseline potential for facial and body traits.

Combining complementary features increases probability of aesthetic offspring.

Lifestyle factors strongly influence gene expression (nutrition, posture, hormones).

Traits like eye color and height are probabilistic, not guaranteed.

Disclaimer:

This post is educational/research focused.
It does not provide medical advice, suggest genetic modification, or endorse trying to design children. Genetics are probabilistic and highly complex.[/SPOILER]
Good read for a greycel post tbh. Props for not using AI to write this shit like most greys
 
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Reactions: Coffeebackwards
Good read for a greycel post tbh. Props for not using AI to write this shit like most greys
I'm trying to get more knowledgeable every day, been into BP since I was 14 and into looksmaxxing since I was 13.
 
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Reactions: Restitutor Orbis

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