Melanotan-2 Guide (Inspired by MPMD)

[Sepsin]

Quick Warning: Before you read this guide, note that melanotan 2 is an injectable peptide with side effects and this is NOT medical advice.

Also, most of the info here is based on more plates more dates original guide.

---

Process Order

1. NO UV EXPOSURE GAINS

Even without uv exposure Melanotan slightly increases skin color by stimulating the MC1R receptor, causing melanocytes to produce a small extra amount of eumelanin even without UV exposure.

Expected darkening (w/o UV exposure): approximately 5–15% of a full summer tan.


2. LOADING PHASE (not rlly)

After several injections, melanocytes become increasingly responsive to UV exposure, producing melanin faster and more efficiently, resulting in a deeper and longer-lasting tan.

During this stage, it’s crucial to combine MT2 administration with UV exposure from the sun or a tanning bed—otherwise, it will not be effective.

Since right now it's starting to get cold asf and the UV index is low (at least in south EU) most of us need to stick to tanning beds


3. MAINTENANCE PHASE

After reaching the desired tan, the maintenance phase begins, requiring less frequent injections (1x p/ week 250mcg) and reduced UV exposure to sustain the color (Keeping the color is act much easier than most people think).

During this stage, the skin begins to repair the damage from the previous phase, as the damage from UV exposure becomes much less necessary. This is the ideal stage we want to get to.

---

Side Effects

Benefits:

• Promotes visceral fat reduction (even excluding gains from appetite suppression)
• Enhances insulin sensitivity (facilitates lean muscle gain)
• Suppresses appetite

*These additional benefits were observed in NIH-conducted studies on mice


Downsides:

• Random erections during the day
• Facial flushing up to 1 hour after injection
• Darkens hair colour (but only in high doses)
• Skin gets compromised in the loading phase, as it requires UV exposure to be effective.

*other side effects like nausea, freckles and darkening of moles shouldn’t happen in low doses administered in relatively short cycles

---

Injection & Tanning Calendar

*This is considering we add 5ml BAC water to the 10mg MT2 Vial

*Once we hit the desired look (even if before day 31) we should immediately transition into the maintenance phase where we do 250/300mcg weekly shots followed by 10 minutes of sun bed.

---

Peptide Reconstitution

Material Needed:

• BAC water
• 10mg vial of melanotan 2
• 3 empty 10mg vial
• U-100 insulin syringes 31G 1cc
• Alcohol wipes

Total Price ~ €120.00 (for 4 months of supply!!!)

*sources: amazon.es & particlepeptides.com


Reconstitution Step-by-Step:

1. Remove the caps
2. Wipe the top of each vial with an alcohol swab
3. Pull back 5ml of BAC water into the syringe
4. Inject it into the melanotan-2 vial
5. Swirl slowly the reconstituted vial (don’t shake it)
6. Pull back 1.25ml of the reconstituted solution (3x times)
7. Inject the 1.25ml into a new sterile vial (3x times)

• Refrigerate one of the vials (use in the 1st month)
• Freeze the other 3 (use in the following months)

Instructions video:

---

Injection Technique

1. Wash your hands
2. Wipe the vial & the injection spot w/ an alcohol swab
3. Draw the desired amount to the syringe
4. Pinch some fat and inject the whole needle at a 45º in the abdomen area

*Optional: Apply EMLA cream 45 minutes before injection.

Instructions video (credits to @Jatt for the video): https://i.looksmax.org/attachments/2025/08/5246726_IMG_3393.mp4

---

UndertoneMaxxing

In order to get the most out of melanotan-2 we should also have the RIGHT UNDERTONES.

Here’s an example of different undertones:

So here’s the Carotenoid Loading for Warmer Undertones:

• Beta-Carotene: 25,000 IU daily.
• Lycopene: 20mg daily.
• Astaxanthin: 4mg daily

---

Thx for reading,
G out for another tanning bed session.

 

[D0RSI]

are there any differences if I'm using nasal mt2 and not pinning it?

 

[Sepsin]

are there any differences if I'm using nasal mt2 and not pinning it?

The bioavailability of nasal spray is shit compared to subQ injections (10x less bioavailable and effective).

Besides that, it's also impossible to know how much actually gets absorbed by the nasal mucosa (making dosages very uncertain).

just pin it brudda.

 

[moggedtomumbai]

Good thread brother!

What is your opinion on different dosing, such as jumping straight in at:

250mcg + 7 mins sunbed time (2x/week)

I am planning to start my first dose tomorrow morning.

 

[Sepsin]

Good thread brother!

What is your opinion on different dosing, such as jumping straight in at:

250mcg + 7 mins sunbed time (2x/week)

I am planning to start my first dose tomorrow morning.

wouldn't recommend that at all.

nausea will hit you like a truck and side effects like moles are much more likely to happen if you jump straight into 250mcg.

pls take a look at the original guide from MPMD, he explains that.

https://moreplatesmoredates.com/melanotan-ii/

 

[eon]

Ur name is fucking i blame @Clavicular and your dropping a melanotan guide


@Luca_. @BigBallsLarry @Orka

In spirit @esoterik

 

[Insomnia]

Ur name is fucking i blame @Clavicular and your dropping a melanotan guide


@Luca_. @BigBallsLarry @Orka

In spirit @esoterik

Reply to the thread I tagged you in bhaijaan
Also

 

[Sepsin]

Ur name is fucking i blame @Clavicular and your dropping a melanotan guide


@Luca_. @BigBallsLarry @Orka

In spirit @esoterik

ahahah it’s hypocritical ik

 

[Sepsin]

Reply to the thread I tagged you in bhaijaan
Also
View attachment 4268243

 

[nik.077]

do you reccomend mt1?

 

[nik.077]

good thread but I believe you need more than 4mg of astaxanthin for a noticable difference in colouring. I personally take 12mg daily and even then there is barely a difference

 

[Sepsin]

do you reccomend mt1?

mt-1 on paper it's better than mt2 due to having less sides.

The problem now is sourcing mt-1 which is very hard, and since the half life is way shorter you also would need much more injections.

tbh just pin mt2 with the cautions I wrote in the guide.

 

[Sepsin]

good thread but I believe you need more than 4mg of astaxanthin for a noticable difference in colouring. I personally take 12mg daily and even then there is barely a difference

thanks for the advice.

Since I take all three 3 supplements together I always noticed a big difference in my undertones, which might mitigate the low dose of astaxanthin

 

[ssxjdgh]

---

Injection & Tanning Calendar

View attachment 4264516

*

What is this a dose for ants? Some of us need 500mg to minimum

 

[Sepsin]

What is this a dose for ants? Some of us need 500mg to minimum

trust the process bro.

These doses have been recommended by MPMD who has more knowledge abt pepetides/steroids than 99% of users in this forum

 

[ssxjdgh]

trust the process bro.

These doses have been recommended by MPMD who has more knowledge abt pepetides/steroids than 99% of users in this forum

I've used melanotan before. 31 days of microdosing aint doing shit unless your already half tanned

 

[Sepsin]

I've used melanotan before. 31 days of microdosing aint doing shit unless your already half tanned

did you combine it with serious UV exposure like I recommend through tanning beds??

 

[ssxjdgh]

did you combine it with serious UV exposure like I recommend through tanning beds??

Yes you're just gonna burn if you do it too early on those doses

 

[Sepsin]

Yes you're just gonna burn if you do it too early on those doses

you absolutely won't since we're talking abt short time sessions, unless you're a literal cumskin (fitzpatrick 1)

 

[Sepsin]

What is this a dose for ants? Some of us need 500mg to minimum

and gl with the side effects at that dose.

moles, nausea and freckles are 10x more likely to happen

 

[ssxjdgh]

you absolutely won't since we're talking abt short time sessions, unless you're a literal cumskin (fitzpatrick 1)

yeah I am

and gl with the side effects at that dose.

moles, nausea and freckles are 10x more likely to happen

yeah thats why I stopped. But low doses did nothing

 

[Sepsin]

yeah I am



yeah thats why I stopped. But low doses did nothing

yeah it makes sense then.

But still if you ramp up slowly until you're doing 250mcg with 10-min tanning bed session, I'm pretty sure you'll get reasonable results without much side effects.

Then, maintaining the color is much easier than most people think, so 2 weekly sessions of those doses (+ tanning beds) might do the job.

 

[ssxjdgh]

yeah it makes sense then.

But still if you ramp up slowly until you're doing 250mcg with 10-min tanning bed session, I'm pretty sure you'll get reasonable results without much side effects.

Then, maintaining the color is much easier than most people think, so 2 weekly sessions of those doses (+ tanning beds) might do the job.

Whats the point of build up so much when you're not getting sun. Also how soon after injecting do you use a bed?

 

[Sepsin]

Whats the point of build up so much when you're not getting sun. Also how soon after injecting do you use a bed?

cause ur body is getting adapted to the increased activity of the MC1R receptor that is producing more melanocytes, and besides your getting UV exposure from tanning beds.

you should be tanning within 1 hour after the injection.

 

[ssxjdgh]

cause ur body is getting adapted to the increased activity of the MC1R receptor that is producing more melanocytes, and besides your getting UV exposure from tanning beds.

you should be tanning within 1 hour after the injection.

Ain't no way im going near sunbed on 75mg JFL

 

[Sepsin]

Ain't no way im going near sunbed on 75mg JFL

ahahah i understand, but c'mon a 5 minute session won't kill you JFL

 

[Bajio]

bookmarked.

 

[Sepsin]

bookmarked.

thx bhai

 

[shneckmax]

Quick Warning: Before you read this guide, note that melanotan 2 is an injectable peptide with side effects and this is NOT medical advice.

Also, most of the info here is based on more plates more dates original guide.

---

Process Order

1. NO UV EXPOSURE GAINS

Even without uv exposure Melanotan slightly increases skin color by stimulating the MC1R receptor, causing melanocytes to produce a small extra amount of eumelanin even without UV exposure.

Expected darkening (w/o UV exposure): approximately 5–15% of a full summer tan.


2. LOADING PHASE (not rlly)

After several injections, melanocytes become increasingly responsive to UV exposure, producing melanin faster and more efficiently, resulting in a deeper and longer-lasting tan.

During this stage, it’s crucial to combine MT2 administration with UV exposure from the sun or a tanning bed—otherwise, it will not be effective.

Since right now it's starting to get cold asf and the UV index is low (at least in south EU) most of us need to stick to tanning beds


3. MAINTENANCE PHASE

After reaching the desired tan, the maintenance phase begins, requiring less frequent injections (1x p/ week 250mcg) and reduced UV exposure to sustain the color (Keeping the color is act much easier than most people think).

During this stage, the skin begins to repair the damage from the previous phase, as the damage from UV exposure becomes much less necessary. This is the ideal stage we want to get to.

---

Side Effects

Benefits:

• Promotes visceral fat reduction (even excluding gains from appetite suppression)
• Enhances insulin sensitivity (facilitates lean muscle gain)
• Suppresses appetite

*These additional benefits were observed in NIH-conducted studies on mice


Downsides:

• Random erections during the day
• Facial flushing up to 1 hour after injection
• Darkens hair colour (but only in high doses)
• Skin gets compromised in the loading phase, as it requires UV exposure to be effective.

*other side effects like nausea, freckles and darkening of moles shouldn’t happen in low doses administered in relatively short cycles

---

Injection & Tanning Calendar

View attachment 4264516

*This is considering we add 5ml BAC water to the 10mg MT2 Vial

*Once we hit the desired look (even if before day 31) we should immediately transition into the maintenance phase where we do 250/300mcg weekly shots followed by 10 minutes of sun bed.

---

Peptide Reconstitution

Material Needed:

• BAC water
• 10mg vial of melanotan 2
• 3 empty 10mg vial
• U-100 insulin syringes 31G 1cc
• Alcohol wipes

Total Price ~ €120.00 (for 4 months of supply!!!)

*sources: amazon.es & particlepeptides.com


Reconstitution Step-by-Step:

1. Remove the caps
2. Wipe the top of each vial with an alcohol swab
3. Pull back 5ml of BAC water into the syringe
4. Inject it into the melanotan-2 vial
5. Swirl slowly the reconstituted vial (don’t shake it)
6. Pull back 1.25ml of the reconstituted solution (3x times)
7. Inject the 1.25ml into a new sterile vial (3x times)

• Refrigerate one of the vials (use in the 1st month)
• Freeze the other 3 (use in the following months)

Instructions video:

---

Injection Technique

1. Wash your hands
2. Wipe the vial & the injection spot w/ an alcohol swab
3. Draw the desired amount to the syringe
4. Pinch some fat and inject the whole needle at a 45º in the abdomen area

*Optional: Apply EMLA cream 45 minutes before injection.

Instructions video (credits to @Jatt for the video): https://i.looksmax.org/attachments/2025/08/5246726_IMG_3393.mp4

---

UndertoneMaxxing

In order to get the most out of melanotan-2 we should also have the RIGHT UNDERTONES.

Here’s an example of different undertones:
View attachment 4265650

So here’s the Carotenoid Loading for Warmer Undertones:

• Beta-Carotene: 25,000 IU daily.
• Lycopene: 20mg daily.
• Astaxanthin: 4mg daily

---

Thx for reading,
G out for another tanning bed session.

not the worst thread I’ve ever seen the undertones advice is good. But I don’t think you’ve ever pinned MT2 bc no one does 5ml of BAC water rofl

also 5ML of BAC water into the syring referring to a insulin syring?

Also this is wrong rofl everyone gets more freckles and moles after MT2 - you would know this if you pinned it thats why I’m 95% sure u haven’t yet

Everything else is good tho

 

[Sepsin]

not the worst thread I’ve ever seen the undertones advice is good. But I don’t think you’ve ever pinned MT2 bc no one does 5ml of BAC water rofl

also 5ML of BAC water into the syring referring to a insulin syring?

View attachment 4332291Also this is wrong rofl everyone gets more freckles and moles after MT2 - you would know this if you pinned it thats why I’m 95% sure u haven’t yet

Everything else is good tho

I def disagree that everyone gets them regardless of dose, MPMD who might be one of the influencers with most knowledge in regards to gear/peptides also states otherwise.

but either way, I appreciate your comment bhai

 

[shneckmax]

I've been doing mt2 for 2 weeks now (here's a photo I took during my very first injection)

View attachment 4332322

and yeah, 5 mL was way too much (I wrote this before starting mt2). I dropped to 3 mL so it fits the vial and it def reduces PIP.

Regarding freckles, I def disagree that everyone gets them regardless of dose. I’m two weeks in with no new moles or freckles (maybe because I’m naturally Fitzpatrick 2/3).

Besides, MPMD who might be one of the influencers with most knowledge in regards to gear/peptides also states otherwise.

View attachment 4332357

but either way, I appreciate your comment bhai

🫩

pin then write guides pls

@Orka @autisticntmaxer⠀ when will I no longer be grey I don’t want to associate with this level

 

[Orka]

View attachment 4332425
View attachment 4332414View attachment 4332415🫩

pin then write guides pls

@Orka @autisticntmaxer⠀ when will I no longer be grey I don’t want to associate with this level

no way

 

[shneckmax]

no way

The larping is out of control

 

[Sepsin]

The larping is out of control

you're right I never pinned.

the larping didn't work

but either way from the research I've done I really feel like the info in the guide is accurate.

 

[shneckmax]

Ur name is fucking i blame @Clavicular and your dropping a melanotan guide


@Luca_. @BigBallsLarry @Orka

In spirit @esoterik

He also has never pinned MT2 and says to draw 5ML of BAC water into 1 insulin syring and reconstitute with that

he also larped with a fake pic of him pinning rofl

 

[eon]

Dude forgot to add the most cucked side effect.

Darkening of sun spots and creating new ones

Megaaa looksmin

 

[eon]

He also has never pinned MT2 and says to draw 5ML of BAC water into 1 insulin syring and reconstitute with that

he also larped with a fake pic of him pinning rofl

5ML?! Is he insane

I reconstituted my melanotan with 3ML and i thought that was to much.

 

[shneckmax]

you're right I never pinned.

the larping didn't work

but either way from the research I've done I really feel like the info in the guide is accurate.

if you are going to write guides you need to pin and try before writing

I’ve tried everything I’ve ever written about and recommended the bad part is your also not giving accurate advice 250mg first time is perfect 75 is way to low rofl

 

[Sepsin]

He also has never pinned MT2 and says to draw 5ML of BAC water into 1 insulin syring and reconstitute with that

he also larped with a fake pic of him pinning rofl

I meant pulling back 5x an insulin syringe to hit 5ml but that prob wouldn't fit the vial, so I'll do taht with 3ml

 

[shneckmax]

5ML?! Is he insane

I reconstituted my melanotan with 3ML and i thought that was to much.

yea I did 2ML rofl I just can’t bothered to refill and reinject into vial more then 2X rofl

They should make a product that makes it easy to reconstitute

 

[shneckmax]

I meant pulling back 5x an insulin syringe to hit 5ml but that prob wouldn't fit the vial, so I'll do taht with 3ml

yes 2-3 at most

 

[Sepsin]

if you are going to write guides you need to pin and try before writing

I’ve tried everything I’ve ever written about and recommended the bad part is your also not giving accurate advice 250mg first time is perfect 75 is way to low rofl

I understand you might have felt fine after pinning 250mcg the first time, but IMO that's not a great advice.

obv everyone has a different experience, but I'll trust more the advice of MPMD who has a shit ton of evidence in this area and says to start at 75mcg and assess from there

 

[Sepsin]

5ML?! Is he insane

I reconstituted my melanotan with 3ML and i thought that was to much.

it's def more than what most people do, but in theory the PIP will also be way better.

 

[eon]

you're right I never pinned.

the larping didn't work

but either way from the research I've done I really feel like the info in the guide is accurate.

Little nigger.

You forgot to add the WORST side effect

As someone who has ran melanotan its a VERY selective peptide, there are only a handful of people who can run it effectively

 

[shneckmax]

I understand you might have felt fine after pinning 250mcg the first time, but IMO that's not a great advice.

obv everyone has a different experience, but I'll trust more the advice of MPMD who has a shit ton of evidence in this area and says to start at 75mcg and assess from there

no rofl 250 won’t really do shit the standard protocol for most research is 1ML like everyday rofl then down to 250. If you do that you will have sides but if you do 250 you will be fine. I also have a MT2 guide but I wrote it after trying.

I will say mirin for taling advice and not just telling people to kill themsleves

Stop larping tho it’s no good

 

[shneckmax]

Little nigger.

You forgot to add the WORST side effect

As someone who has ran melanotan its a VERY selective peptide, there are only a handful of people who can run it effectively

bro first time I ever pinned MT2 I went outside for 1hr and holy shit that was such a retartedmaxx rofl

I was a lobster for like 1-2weeks and my burn itched so bad

This is all just basic stuff be wrote from a convo with chat gpt or possibly reading some surface guides rofl

 

[Sepsin]

Little nigger.

You forgot to add the WORST side effect

As someone who has ran melanotan its a VERY selective peptide, there are only a handful of people who can run it effectively

From what I’ve researched, sun spots happen when you get too much uncontrolled UV exposure, depending on how long you’re in the sun and which areas are exposed

So if you're doing mt2 in combination with a tanning bed, your UV exposure will be as controlled as it gets, besides we're increasing gradually the time of the session and the injection amount.

Therefore, most people (unless they're literal cumskin) won't have that side effect.

 

[Greyascension]

Ur name is fucking i blame @Clavicular and your dropping a melanotan guide


@Luca_. @BigBallsLarry @Orka

In spirit @esoterik

"In spirit"

 

[Greyascension]

Little nigger.

You forgot to add the WORST side effect

As someone who has ran melanotan its a VERY selective peptide, there are only a handful of people who can run it effectively

Ts bhai right and smart ts Diddy bhai correct ts eon is blonde with blue eyes and tanned I swear

 

[Sepsin]

bro first time I ever pinned MT2 I went outside for 1hr and holy shit that was such a retartedmaxx rofl

I was a lobster for like 1-2weeks and my burn itched so bad

This is all just basic stuff be wrote from a convo with chat gpt or possibly reading some surface guides rofl

none of the info was produced by gpt itself, it was just research gathered from different guides and then chatgpt helped with writing (since I'm a non native english speaker).