Minoxidil&Collagen - PSL consensus in 2020

[Chico Chicowski]

not even on beard but on scalp - will rape me?

 

[noorwoodinfinite]

If you look on the studies of minoxidil blocking collagen(it isnt true because it is actually block one of a few enzymes required for building collagen) the unit in which minoxidil blocks lysyl hydroxylase is >25 mcg/ml while even if you taking it orally for hair growth (10 mg doses which is upper range for that)) you having blood concentration about 60-10 ng/ml so 1000 smaller concentration so it is impossible to block collagen in human body... also If minoxidil would ever blocks collagen building then why when it was studied orally for hypertension in high doses like 20+ mg orally it doesnt cause any sides effects related to decreased collagen production? Like we see in scurvy so gums bleeding, weak wound healing, joint pain etc ? Topical minoxidil contains alcohol which can dry out your skin (which makes skin worse) but it is unlikely that minoxidil block collagen production.

 

[Chico Chicowski]

If you look on the studies of minoxidil blocking collagen(it isnt true because it is actually block one of a few enzymes required for building collagen) the unit in which minoxidil blocks lysyl hydroxylase is >25 mcg/ml while even if you taking it orally for hair growth (10 mg doses which is upper range for that)) you having blood concentration about 60-10 ng/ml so 1000 smaller concentration so it is impossible to block collagen in human body... also If minoxidil would ever blocks collagen building then why when it was studied orally for hypertension in high doses like 20+ mg orally it doesnt cause any sides effects related to decreased collagen production? Like we see in scurvy so gums bleeding, weak wound healing, joint pain etc ? Topical minoxidil contains alcohol which can dry out your skin (which makes skin worse) but it is unlikely that minoxidil block collagen production.

is theere any alcohol-free lower-rish minox on market?

 

[DrunkenSailor]

Just hop on Retin-A

 

[RAITEIII]

If you look on the studies of minoxidil blocking collagen(it isnt true because it is actually block one of a few enzymes required for building collagen) the unit in which minoxidil blocks lysyl hydroxylase is >25 mcg/ml while even if you taking it orally for hair growth (10 mg doses which is upper range for that)) you having blood concentration about 60-10 ng/ml so 1000 smaller concentration so it is impossible to block collagen in human body... also If minoxidil would ever blocks collagen building then why when it was studied orally for hypertension in high doses like 20+ mg orally it doesnt cause any sides effects related to decreased collagen production? Like we see in scurvy so gums bleeding, weak wound healing, joint pain etc ? Topical minoxidil contains alcohol which can dry out your skin (which makes skin worse) but it is unlikely that minoxidil block collagen production.

What about how it affects androgen receptors (and subsequently collagen)?

 

[Good_Little_Goy]

If you look on the studies of minoxidil blocking collagen(it isnt true because it is actually block one of a few enzymes required for building collagen) the unit in which minoxidil blocks lysyl hydroxylase is >25 mcg/ml while even if you taking it orally for hair growth (10 mg doses which is upper range for that)) you having blood concentration about 60-10 ng/ml so 1000 smaller concentration so it is impossible to block collagen in human body... also If minoxidil would ever blocks collagen building then why when it was studied orally for hypertension in high doses like 20+ mg orally it doesnt cause any sides effects related to decreased collagen production? Like we see in scurvy so gums bleeding, weak wound healing, joint pain etc ? Topical minoxidil contains alcohol which can dry out your skin (which makes skin worse) but it is unlikely that minoxidil block collagen production.

there are different types of collagen in the joints, skin, tissues and such which are synthesised different ways so the mechanism in which it could affect collagen synthesis could only happen topically.

devils advocate though idk enough to say either way

 

[Donc0ck]

Using it since 4 years on beard and starting improving skincare at that time. My skin is now better looking than 4 years ago and I got a nice beard.

 

[eduardkoopman]

not even on beard but on scalp - will rape me?

I use minox on upper head.
I'm 37.
I have skin quality of a 20 something year old.
Just CollagenMaxx, and that should compensate mopre then enough for the Minox.
dermaroller, daily sunblock spf 50 UVA UVB, red light therapy, tretinoin possibly, retinol, etc..