MK-677 and DIET

[Mrinfinityx]

I am tempted to take it for my bone remodeling journey

But the scary effect is the permanent high blood sugar and insuline resistance generated by the product that occurs 24h for each intake

I know already it is better to take it at rest some hours after the last meal and before bed so (in rest insulinic state so)

But I think the intake of this product should require a specific diet and lifestyle to don't fall off in diabetic state

 

[Mrinfinityx]

If there is any takers what are your recommendations?

 

[Cali Yuga]

try fasting or doing 0mad with keto macros or something

will reset your insulin resistance and keep your blood sugar as low as possible

what is the mechanism that causes the resistance/high blood sugar?

 

[Mrinfinityx]

try fasting or doing 0mad with keto macros or something

will reset your insulin resistance and keep your blood sugar as low as possible

what is the mechanism that causes the resistance/high blood sugar?

@Cali Yuga

Thx, here is one of the articles
I dont know yet the reason behind it, maybe correlated to IGF1 elevation during the intake

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial - PubMed

Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated. Long-term functional and, ultimately, pharmacoeconomic, studies in elderly persons are indicated.

pubmed.ncbi.nlm.nih.gov

 

[Mrinfinityx]

try fasting or doing 0mad with keto macros or something

will reset your insulin resistance and keep your blood sugar as low as possible

what is the mechanism that causes the resistance/high blood sugar?

@Cali Yuga

Ok so I skip high glycemic indice food as much as possible

I am still overweight here so I need to keep great cautions to my glycemic system

 

[Cali Yuga]

Thx here is one of the articles

Effects of an oral ghrelin mimetic on body composition and clinical outcomes in healthy older adults: a randomized trial - PubMed

Over 12 months, the ghrelin mimetic MK-677 enhanced pulsatile growth hormone secretion, significantly increased fat-free mass, and was generally well tolerated. Long-term functional and, ultimately, pharmacoeconomic, studies in elderly persons are indicated.

pubmed.ncbi.nlm.nih.gov

keto+fasting will reduce endogenous ghrelin production, might help the body get back to homeostasis faster

Ok so I skip high glycemic indice food as much as possible

Should be doing this anyway tbh

 

[Mrinfinityx]

keto+fasting will reduce endogenous ghrelin production, might help the body get back to homeostasis faster


Should be doing this anyway tbh

@Cali Yuga

Of course the overweight part can still be a remaining problem, maybe I will try to be hyperactive physically before envisaging taking it

 

[SteveRogers]

try fasting or doing 0mad with keto macros or something

will reset your insulin resistance and keep your blood sugar as low as possible

what is the mechanism that causes the resistance/high blood sugar?

100%
you didn’t happen to listen to Elliott Hulse’ podcast with the Snake Diet dude did you?