on caffeine.

[Orc]

 

[xegigi]

might watch l8r

 

[descension]

Caffeine is not doing allat

 

[tigrxs]

Can you summarise it, please?

 

[Deleted member 23558]

its the same thing hes peddling that in mainstream for 20 years, nothing new about this, and on the chess thing , caffeine not good at all for rapid cos u start seeing new potentialities that u keep waiting to find better move while without it u just make the move. Its not good comparison, they should check it on classical time format.

Caffeine also differs in experience wrt liver function and carb intake, high carb intake and good liver function make caffeine a different drug- very nootropic

 

[mrmogger2882]

Made my dick smaller JFL

 

[Orc]

can you summarise it please

tl;dr

1. the positive cognitive benefits of caffeine are only present short term and long term the same components decline.
2. sleep is negatively impacted if you consume any caffeine at all within a 9-13 hour period before you go to bed.
3. many of the benefits are placebo.
4. higher dosages do not cause greater effect.
5. you become tolerant to it quickly.
   

 

[Deleted member 55855]

did watch while drinking a white monster preparing for a night lift

 

[xegigi]

tl;dr

1. the positive cognitive benefits of caffeine are only present short term and long term the same components decline.
2. sleep is negatively impacted if you consume any caffeine at all within a 9-13 hour period before you go to bed.
3. many of the benefits are placebo.
4. higher dosages do not cause greater effect.
5. you become tolerant to it quickly.

so water then

 

[Orc]

so water then

more or less yet people are still chugging mud water daily.

 

[ilovenicotine]

its the same thing hes peddling that in mainstream for 20 years, nothing new about this, and on the chess thing , caffeine not good at all for rapid cos u start seeing new potentialities that u keep waiting to find better move while without it u just make the move. Its not good comparison, they should check it on classical time format.

Caffeine also differs in experience wrt liver function and carb intake, high carb intake and good liver function make caffeine a different drug- very nootropic

Water, of course drugs are bad no matter how mild.

 

[ChadL1te]

Fuck all of that, Im still gonna drink 500mg a day

 

[tigrxs]

tl;dr

1. the positive cognitive benefits of caffeine are only present short term and long term the same components decline.
2. sleep is negatively impacted if you consume any caffeine at all within a 9-13 hour period before you go to bed.
3. many of the benefits are placebo.
4. higher dosages do not cause greater effect.
5. you become tolerant to it quickly.

thank you

 

[ChadL1te]

Made my dick smaller JFL

Stim dick

 

[xegigi]

more or less yet people are still chugging mud water daily.

'tis a drug after all

 

[Deleted member 23558]

Water, of course drugs are bad no matter how mild.

its not bad though. It depends on liver function, before or after meal, age , whether caffeine is taken with or without sucrose, thyroid status etc

 

[ilovenicotine]

its not bad though. It depends on liver function, before or after meal, age , whether caffeine is taken with or without sucrose, thyroid status etc

Of course. The positives outweigh the negatives of caffeine. It’s why it’s the most used drug in the world

 

[Deleted member 23558]

Of course. The positives outweigh the negatives of caffeine. It’s why it’s the most used drug in the world

caffeine plus b1 is essentialy the cure for CFS

 

[Orc]

Of course. The positives outweigh the negatives of caffeine. It’s why it’s the most used drug in the world

they don't.

there's no long term positives from caffeine, everything it improves short term becomes worse long term.

 

[caiolindo]

they don't.

there's no long term positives from caffeine, everything it improves short term becomes worse long term.

caffeine debloats me

 

[Orc]

caffeine debloats me

not eating debloats me.

 

[caiolindo]

not eating debloats me.

me too

 

[sub5outsider]

i dont drink coffee

 

[Deleted member 23558]

they don't.

there's no long term positives from caffeine, everything it improves short term becomes worse long term.

Spoiler

Breast Cancer Res Treat 1991 Nov;19(3):269-75. Caffeine inhibits development of benign mammary gland tumors in carcinogen-treated female Sprague-Dawley rats. Wolfrom DM, Rao AR, Welsch CW.

Cancer 1985 Oct 15;56(8):1977-81. The inhibitory effect of caffeine on hormone-induced rat breast cancer. Petrek JA, Sandberg WA, Cole MN, Silberman MS, Collins DC. “The current investigation examines the effect of two caffeine doses in ACI rats with and without diethylstilbestrol (DES). Without DES, cancer did not develop in any of the rats receiving either of the two caffeine dosages. With DES, increasing caffeine dosage lengthened the time to first cancer, decreased the number of rats that developed cancers, and decreased the number of cancers overall.” “In conclusion, chronic caffeine ingestion inhibits rat breast cancer, neither by interfering with the high prolactin levels--a necessary step in murine tumor development--nor by causing hypocaloric intake.”

Nutr Cancer 1998;30(1):21-4. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nagata C, Kabuto M, Shimizu H. “Although the effect of caffeine cannot be distinguished from effects of coffee and green tea, consumption of caffeine-containing beverages appeared to favorably alter hormone levels associated with the risk of developing breast cancer.”

J Environ Pathol Toxicol Oncol 1992; 11(3):177-89. Caffeine, theophylline, theobromine, and developmental growth of the mouse mammary gland.VanderPloeg LC, Wolfrom DM, Rao AR, Braselton WE, Welsch CW. “These data demonstrate that certain methylxanthines (e.g., caffeine and theophylline) but not others (e.g., theobromine) can significantly enhance mammotrophic hormone-induced mammary lobulo-alveolar differentiation in female Balb/c mice, an effect that appears not to be manifested via a direct action of the methylxanthines on the mammary gland.”

J Environ Pathol Toxicol Oncol 1994;13(2):81-8. Enhancement by caffeine of mammary gland lobulo-alveolar development in mice: a function of increased corticosterone. Welsch CW, VanderPloeg LC. Previously we have reported that the stimulatory effect of caffeine on lobulo-alveolar development in the mammary glands of female Balb/c mice is not due to a direct action of the drug on the mammary gland but appears to be due to a caffeine-induced alteration of a yet to be defined systemic physiological process (VanderPloeg et al., J Environ Pathol Toxicol Oncol 11:177-189, 1992). “In the present study, we administered caffeine (via the drinking water, 500 mg/L) to ovariectomized, estrogen- and progesterone-treated Balb/c mice. After 30 days of caffeine treatment, a significant (p < 0.001) enhancement of lobulo-alveolar development in the mammary glands of the hormone-treated mice, compared with hormone treated control mice, was observed.”

Am J Clin Nutr 1997 Jun;65(6):1826-30. Dietary caffeine intake and bone status of postmenopausal women. Lloyd T, Rollings N, Eggli DF, Kieselhorst K, Chinchilli VM.

Eur J Epidemiol 1993 May;9(3):293-7. Unexpected effects of coffee consumption on liver enzymes. Casiglia E, Spolaore P, Ginocchio G, Ambrosio GB. Istituto di Medicina Clinica, Universita di Padova, Italy. The effects of regular daily coffee consumption on liver enzymes were studied in a large number of subjects from the general population. In coffee drinkers, liver enzymes (gamma-glutamyl transferase, alanine-amino transferase, and alkaline phosphatase) and serum bilirubin were lower than in non-coffee-drinking subjects or in those consuming less than 3 cups daily. The hypothesis proposed is that liver enzymes are a target for caffeine contained in coffee.

Anticancer Res 1996 Jan-Feb;16(1):151-3 Suppression by coffee cherry of the growth of spontaneous mammary tumours in SHN mice. Nagasawa H, Yasuda M, Sakamoto S, Inatomi H Experimental Animal Research Laboratory, Meiji University, Kanagawa, Japan. We previously found that coffee cherry (CC), residue after removal of coffee beans, significantly suppressed the development of spontaneous mammary tumours of mice. In this paper, the effects of CC on the growth of the palpable size of this type of tumour was examined. Free access as drinking water of 0.5% solution of the hot water extract of CC for 10 days resulted in a marked inhibition of the tumour growth: The percent changes of tumour sizes were 53.8 +/- 11.7% and 13.8 +/- 10.9% in the control and the experimental groups, respectively. Associated with this, thymidylate synthetase activity in the mammary tumours was significantly lower in the experimental group than in the control. Normal and preneoplastic mammary gland growth, body weight change and weights and structures of endocrine organs were only slightly affected by the treatment. The findings indicate that CC is promising as an antitumour agent.

Yakugaku Zasshi 1997 Jul;117(7):448-54. [Effect of tea extracts, catechin and caffeine against type-I allergic reaction]. [Article in Japanese] Shiozaki T, Sugiyama K, Nakazato K, Takeo T. “Caffeine also showed a inhibitory effect on the PCA reaction. These results indicate that tea could provide a significant protection against the type-I allergic reaction. These findings also suggest that tea catechins and caffeine play an important role in having an inhibitory effect on the type-I allergic reaction.”

Acta Chir Scand 1989 Jun-Jul;155(6-7):317-20. Does coffee consumption protect against thyroid disease? Linos A, Linos DA, Vgotza N, Souvatzoglou A, Koutras DA

Br J Nutr 1999 Aug;82(2):125-30. Inverse association between coffee drinking and serum uric acid concentrations in middle-aged Japanese males. Kiyohara C, Kono S, Honjo S, Todoroki I, Sakurai Y, Nishiwaki M, Hamada H, Nishikawa H, Koga H, Ogawa S, Nakagawa K

Cancer Res 1997 Jul 1;57(13):2623-9. Effects of tea, decaffeinated tea, and caffeine on UVB light-induced complete carcinogenesis in SKH-1 mice: demonstration of caffeine as a biologically important constituent of tea. Huang MT, Xie JG, Wang ZY, Ho CT, Lou YR, Wang CX, Hard GC, Conney A.H.

Mutat Res 1981 Jun;89(2):161-77. Non-mutagenicity of urine from coffee drinkers compared with that from cigarette smokers. Aeschbacher HU, Chappuis C.

Biol Neonate 1981;40(3-4):196-8. The effects of maternal carbohydrate (sucrose) supplementation on the growth of offspring of pregnancies with habitual caffeine consumption. Dunlop M, Court JM, Larkins RG. “When maternal caffeine (10 mg/kg/day) was consumed together with supplementary sucrose (7 g/kg/day) the expected offspring growth reduction attributed to caffeine did not occur.”

Biochim Biophys Acta 1992 Dec 15;1175(1):114-22. Caffeine promotes survival of cultured sympathetic neurons deprived of nerve growth factor through a cAMP-dependent mechanism. Tanaka S, Koike T.

JAMA 2000 May 24-31;283(20):2674-9. Association of coffee and caffeine intake with the risk of Parkinson disease. Ross GW, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR.

Farmakol Toksikol 1983 Sep-Oct;46(5):107-11 [Use of the swimming test for demonstrating antidepressive activity of drugs during single and repeated administration]. [Article in Russian] Rusakov DIu, Val'dman AV. “The use of the "swimming test" made it possible to identify the activity of tricyclic (desipramine, chlorimipramine, amitryptyline) and atypical antidepressants (befuralin, zimelidine, trazodon), that of pyrazidol (type A MAO inhibitor) and of a number of new compounds--derivatives of benzofuran and morpholine upon single and chronic administration. To define the method specificity, use was made of the neuroleptic haloperidol, the tranquilizer diazepam, and of nembutal, which did not exhibit any activity in the test in question.Psychostimulants (amphetamine, caffeine) dramatically increased the time of active swimming. The effect lasted throughout all the 30 minutes of testing, which is not characteristic for antidepressants.”

Gen Pharmacol 1996 Jan;27(1):167-70 The influence of antagonists of poly(ADP-ribose) metabolism on acetaminophen hepatotoxicity. Kroger H, Ehrlich W, Klewer M, Gratz R, Dietrich A, Miesel R.

Ann Clin Lab Sci 1977 Jan-Feb;7(1):68-72. Effects of drugs on platelet function.Morse EE.

Thromb Haemost 1982 Apr 30;47(2):90-5. Effect of cAMP phosphodiesterase inhibitors on ADP-induced shape change, cAMP and nucleoside diphosphokinase activity of rabbit platelets. Lam SC, Guccione MA, Packham MA, Mustard JF.

Carcinogenesis 1998 Aug;19(8):1369-75. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Cavin C, Holzhauser D, Constable A, Huggett AC, Schilter B.

Am J Epidemiol 1994 Apr 1;139(7):723-7. Coffee and serum gamma-glutamyltransferase: a study of self-defense officials in Japan. Kono S, Shinchi K, Imanishi K, Todoroki I, Hatsuse K.

Carcinogenesis 1996 Nov;17(11):2377-84 Placental glutathione S-transferase (GST-P) induction as a potential mechanism for the anti-carcinogenic effect of the coffee-specific components cafestol and kahweol. Schilter B, Perrin I, Cavin C, Huggett AC

J Nutr 1999 Jul;129(7):1361-7. Teas and other beverages suppress D-galactosamine-induced liver injury in rats. Sugiyama K, He P, Wada S, Saeki S

Nutr Cancer 1999;33(2):146-53. Effects of oral administration of tea,decaffeinated tea, and caffeine on the formation and growth of tumors in high-risk SKH-1 mice previously treated with ultraviolet B light. Lou YR, Lu YP, Xie JG, Huang MT, Conney AH.

Ind Health 2000 Jan;38(1):99-102. Effects of coffee consumption against the development of liver dysfunction: a 4-year follow-up study of middle-aged Japanese male office workers. Nakanishi N, Nakamura K, Suzuki K, Tatara K.

Ind Health 2000 Jan;38(1):99-102. Effects of coffee consumption against the development of liver dysfunction: a 4-year follow-up study of middle-aged Japanese male office workers. Nakanishi N, Nakamura K, Suzuki K, Tatara K. .

Biochim Biophys Acta 1992 Dec 15; 1175(1):114-22. Caffeine promotes survival of cultured sympathetic neurons deprived of nerve growth factor through a cAMP-dependent mechanism. Tanaka S, Koike T.

Int J Epidemiol 1998 Jun;27(3):438-43. Coffee consumption and decreased serum gamma-glutamyltransferase and aminotransferase activities among male alcohol drinkers. Tanaka K, Tokunaga S, Kono S, Tokudome S, Akamatsu T, Moriyama T, Zakouji H. “. . . recent epidemiological studies have suggested unexpected, possibly beneficial effects of coffee against the occurrence of alcoholic liver cirrhosis and upon serum liver enzyme levels.” “Increased coffee consumption was strongly and independently associated with decreased GGT activity among males (P trend < 0.0001); the inverse association between coffee and serum GGT was more evident among heavier alcohol consumers (P < 0.0001), and was absent among non-alcohol drinkers.” “Similar inverse associations with coffee and interactions between coffee and alcohol intake were observed for serum aspartate aminotransferase and alanine aminotransferase. Intake of green tea, another popular source of caffeine in Japan, did not materially influence the liver enzyme levels. CONCLUSIONS: Our results suggest that coffee may inhibit the induction of GGT in the liver by alcohol consumption, and may possibly protect against liver cell damage due to alcohol.”​

 

[Orc]

Spoiler

Breast Cancer Res Treat 1991 Nov;19(3):269-75. Caffeine inhibits development of benign mammary gland tumors in carcinogen-treated female Sprague-Dawley rats. Wolfrom DM, Rao AR, Welsch CW.

Cancer 1985 Oct 15;56(8):1977-81. The inhibitory effect of caffeine on hormone-induced rat breast cancer. Petrek JA, Sandberg WA, Cole MN, Silberman MS, Collins DC. “The current investigation examines the effect of two caffeine doses in ACI rats with and without diethylstilbestrol (DES). Without DES, cancer did not develop in any of the rats receiving either of the two caffeine dosages. With DES, increasing caffeine dosage lengthened the time to first cancer, decreased the number of rats that developed cancers, and decreased the number of cancers overall.” “In conclusion, chronic caffeine ingestion inhibits rat breast cancer, neither by interfering with the high prolactin levels--a necessary step in murine tumor development--nor by causing hypocaloric intake.”

Nutr Cancer 1998;30(1):21-4. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenopausal Japanese women. Nagata C, Kabuto M, Shimizu H. “Although the effect of caffeine cannot be distinguished from effects of coffee and green tea, consumption of caffeine-containing beverages appeared to favorably alter hormone levels associated with the risk of developing breast cancer.”

J Environ Pathol Toxicol Oncol 1992; 11(3):177-89. Caffeine, theophylline, theobromine, and developmental growth of the mouse mammary gland.VanderPloeg LC, Wolfrom DM, Rao AR, Braselton WE, Welsch CW. “These data demonstrate that certain methylxanthines (e.g., caffeine and theophylline) but not others (e.g., theobromine) can significantly enhance mammotrophic hormone-induced mammary lobulo-alveolar differentiation in female Balb/c mice, an effect that appears not to be manifested via a direct action of the methylxanthines on the mammary gland.”

J Environ Pathol Toxicol Oncol 1994;13(2):81-8. Enhancement by caffeine of mammary gland lobulo-alveolar development in mice: a function of increased corticosterone. Welsch CW, VanderPloeg LC. Previously we have reported that the stimulatory effect of caffeine on lobulo-alveolar development in the mammary glands of female Balb/c mice is not due to a direct action of the drug on the mammary gland but appears to be due to a caffeine-induced alteration of a yet to be defined systemic physiological process (VanderPloeg et al., J Environ Pathol Toxicol Oncol 11:177-189, 1992). “In the present study, we administered caffeine (via the drinking water, 500 mg/L) to ovariectomized, estrogen- and progesterone-treated Balb/c mice. After 30 days of caffeine treatment, a significant (p < 0.001) enhancement of lobulo-alveolar development in the mammary glands of the hormone-treated mice, compared with hormone treated control mice, was observed.”

Am J Clin Nutr 1997 Jun;65(6):1826-30. Dietary caffeine intake and bone status of postmenopausal women. Lloyd T, Rollings N, Eggli DF, Kieselhorst K, Chinchilli VM.

Eur J Epidemiol 1993 May;9(3):293-7. Unexpected effects of coffee consumption on liver enzymes. Casiglia E, Spolaore P, Ginocchio G, Ambrosio GB. Istituto di Medicina Clinica, Universita di Padova, Italy. The effects of regular daily coffee consumption on liver enzymes were studied in a large number of subjects from the general population. In coffee drinkers, liver enzymes (gamma-glutamyl transferase, alanine-amino transferase, and alkaline phosphatase) and serum bilirubin were lower than in non-coffee-drinking subjects or in those consuming less than 3 cups daily. The hypothesis proposed is that liver enzymes are a target for caffeine contained in coffee.

Anticancer Res 1996 Jan-Feb;16(1):151-3 Suppression by coffee cherry of the growth of spontaneous mammary tumours in SHN mice. Nagasawa H, Yasuda M, Sakamoto S, Inatomi H Experimental Animal Research Laboratory, Meiji University, Kanagawa, Japan. We previously found that coffee cherry (CC), residue after removal of coffee beans, significantly suppressed the development of spontaneous mammary tumours of mice. In this paper, the effects of CC on the growth of the palpable size of this type of tumour was examined. Free access as drinking water of 0.5% solution of the hot water extract of CC for 10 days resulted in a marked inhibition of the tumour growth: The percent changes of tumour sizes were 53.8 +/- 11.7% and 13.8 +/- 10.9% in the control and the experimental groups, respectively. Associated with this, thymidylate synthetase activity in the mammary tumours was significantly lower in the experimental group than in the control. Normal and preneoplastic mammary gland growth, body weight change and weights and structures of endocrine organs were only slightly affected by the treatment. The findings indicate that CC is promising as an antitumour agent.

Yakugaku Zasshi 1997 Jul;117(7):448-54. [Effect of tea extracts, catechin and caffeine against type-I allergic reaction]. [Article in Japanese] Shiozaki T, Sugiyama K, Nakazato K, Takeo T. “Caffeine also showed a inhibitory effect on the PCA reaction. These results indicate that tea could provide a significant protection against the type-I allergic reaction. These findings also suggest that tea catechins and caffeine play an important role in having an inhibitory effect on the type-I allergic reaction.”

Acta Chir Scand 1989 Jun-Jul;155(6-7):317-20. Does coffee consumption protect against thyroid disease? Linos A, Linos DA, Vgotza N, Souvatzoglou A, Koutras DA

Br J Nutr 1999 Aug;82(2):125-30. Inverse association between coffee drinking and serum uric acid concentrations in middle-aged Japanese males. Kiyohara C, Kono S, Honjo S, Todoroki I, Sakurai Y, Nishiwaki M, Hamada H, Nishikawa H, Koga H, Ogawa S, Nakagawa K

Cancer Res 1997 Jul 1;57(13):2623-9. Effects of tea, decaffeinated tea, and caffeine on UVB light-induced complete carcinogenesis in SKH-1 mice: demonstration of caffeine as a biologically important constituent of tea. Huang MT, Xie JG, Wang ZY, Ho CT, Lou YR, Wang CX, Hard GC, Conney A.H.

Mutat Res 1981 Jun;89(2):161-77. Non-mutagenicity of urine from coffee drinkers compared with that from cigarette smokers. Aeschbacher HU, Chappuis C.

Biol Neonate 1981;40(3-4):196-8. The effects of maternal carbohydrate (sucrose) supplementation on the growth of offspring of pregnancies with habitual caffeine consumption. Dunlop M, Court JM, Larkins RG. “When maternal caffeine (10 mg/kg/day) was consumed together with supplementary sucrose (7 g/kg/day) the expected offspring growth reduction attributed to caffeine did not occur.”

Biochim Biophys Acta 1992 Dec 15;1175(1):114-22. Caffeine promotes survival of cultured sympathetic neurons deprived of nerve growth factor through a cAMP-dependent mechanism. Tanaka S, Koike T.

JAMA 2000 May 24-31;283(20):2674-9. Association of coffee and caffeine intake with the risk of Parkinson disease. Ross GW, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR.

Farmakol Toksikol 1983 Sep-Oct;46(5):107-11 [Use of the swimming test for demonstrating antidepressive activity of drugs during single and repeated administration]. [Article in Russian] Rusakov DIu, Val'dman AV. “The use of the "swimming test" made it possible to identify the activity of tricyclic (desipramine, chlorimipramine, amitryptyline) and atypical antidepressants (befuralin, zimelidine, trazodon), that of pyrazidol (type A MAO inhibitor) and of a number of new compounds--derivatives of benzofuran and morpholine upon single and chronic administration. To define the method specificity, use was made of the neuroleptic haloperidol, the tranquilizer diazepam, and of nembutal, which did not exhibit any activity in the test in question.Psychostimulants (amphetamine, caffeine) dramatically increased the time of active swimming. The effect lasted throughout all the 30 minutes of testing, which is not characteristic for antidepressants.”

Gen Pharmacol 1996 Jan;27(1):167-70 The influence of antagonists of poly(ADP-ribose) metabolism on acetaminophen hepatotoxicity. Kroger H, Ehrlich W, Klewer M, Gratz R, Dietrich A, Miesel R.

Ann Clin Lab Sci 1977 Jan-Feb;7(1):68-72. Effects of drugs on platelet function.Morse EE.

Thromb Haemost 1982 Apr 30;47(2):90-5. Effect of cAMP phosphodiesterase inhibitors on ADP-induced shape change, cAMP and nucleoside diphosphokinase activity of rabbit platelets. Lam SC, Guccione MA, Packham MA, Mustard JF.

Carcinogenesis 1998 Aug;19(8):1369-75. The coffee-specific diterpenes cafestol and kahweol protect against aflatoxin B1-induced genotoxicity through a dual mechanism. Cavin C, Holzhauser D, Constable A, Huggett AC, Schilter B.

Am J Epidemiol 1994 Apr 1;139(7):723-7. Coffee and serum gamma-glutamyltransferase: a study of self-defense officials in Japan. Kono S, Shinchi K, Imanishi K, Todoroki I, Hatsuse K.

Carcinogenesis 1996 Nov;17(11):2377-84 Placental glutathione S-transferase (GST-P) induction as a potential mechanism for the anti-carcinogenic effect of the coffee-specific components cafestol and kahweol. Schilter B, Perrin I, Cavin C, Huggett AC

J Nutr 1999 Jul;129(7):1361-7. Teas and other beverages suppress D-galactosamine-induced liver injury in rats. Sugiyama K, He P, Wada S, Saeki S

Nutr Cancer 1999;33(2):146-53. Effects of oral administration of tea,decaffeinated tea, and caffeine on the formation and growth of tumors in high-risk SKH-1 mice previously treated with ultraviolet B light. Lou YR, Lu YP, Xie JG, Huang MT, Conney AH.

Ind Health 2000 Jan;38(1):99-102. Effects of coffee consumption against the development of liver dysfunction: a 4-year follow-up study of middle-aged Japanese male office workers. Nakanishi N, Nakamura K, Suzuki K, Tatara K.

Ind Health 2000 Jan;38(1):99-102. Effects of coffee consumption against the development of liver dysfunction: a 4-year follow-up study of middle-aged Japanese male office workers. Nakanishi N, Nakamura K, Suzuki K, Tatara K. .

Biochim Biophys Acta 1992 Dec 15; 1175(1):114-22. Caffeine promotes survival of cultured sympathetic neurons deprived of nerve growth factor through a cAMP-dependent mechanism. Tanaka S, Koike T.

Int J Epidemiol 1998 Jun;27(3):438-43. Coffee consumption and decreased serum gamma-glutamyltransferase and aminotransferase activities among male alcohol drinkers. Tanaka K, Tokunaga S, Kono S, Tokudome S, Akamatsu T, Moriyama T, Zakouji H. “. . . recent epidemiological studies have suggested unexpected, possibly beneficial effects of coffee against the occurrence of alcoholic liver cirrhosis and upon serum liver enzyme levels.” “Increased coffee consumption was strongly and independently associated with decreased GGT activity among males (P trend < 0.0001); the inverse association between coffee and serum GGT was more evident among heavier alcohol consumers (P < 0.0001), and was absent among non-alcohol drinkers.” “Similar inverse associations with coffee and interactions between coffee and alcohol intake were observed for serum aspartate aminotransferase and alanine aminotransferase. Intake of green tea, another popular source of caffeine in Japan, did not materially influence the liver enzyme levels. CONCLUSIONS: Our results suggest that coffee may inhibit the induction of GGT in the liver by alcohol consumption, and may possibly protect against liver cell damage due to alcohol.”​

you are not a pregnant or post menopausal woman, alcoholic, chain smoker, and cancer risk is fundamentally caused by conscious lifestyle decisions so any impact it makes on that is negated by the fact that you have a dismal risk to begin with if you aren't poisoning yourself, everything you posted is very useless.

 

[Diarrhoea]

you are not a pregnant or post menopausal woman, alcoholic, chain smoker, and cancer risk is fundamentally caused by conscious lifestyle decisions so any impact it makes on that is negated by the fact that you have a dismal risk to begin with if you aren't poisoning yourself, everything you posted is very useless.

What are the measurements of ur waist and hips unc just wondering because ur waist looks like it shrunk a lot in ur transformation

 

[Orc]

What are the measurements of ur waist and hips unc just wondering because ur waist looks like it shrunk a lot in ur transformation

my before pictures are always leaning back + scapula retracted because I had a muscle imbalance and can't flex my abs without bending.

my waist sits around 29 usually.
hips are around 31, but I store a lot of fat on my lower back that's invisible from the sides so it's potentially smaller than that.

 

[Diarrhoea]

my before pictures are always leaning back + scapula retracted because I had a muscle imbalance and can't flex my abs without bending.

my waist sits around 29 usually.
hips are around 31, but I store a lot of fat on my lower back that's invisible from the sides so it's potentially smaller than that.

Alr Thanks

 

[DR. NICKGA]

Blaaaaaa blaaaaaa blaaaaaa blaaaaa

Ultra High Caffeine , Ultra high sugar coffee give me energy and makee mee warm!

I got no side effects

 

[ilovenicotine]

they don't.

there's no long term positives from caffeine, everything it improves short term becomes worse long term.

water, tolerance exists. Managing your intake to gain the maximum benefits of caffeine. The short term mild high of caffeine is better than the negative health effects

 

[karpeltunnel]

caffine is not metabolized by all people equally, so any negative or positive experiences can be felt by one group and not the other. As long as you don't drink to much, late at night, or right after waking up most people find almost no drawbacks from drinking it. I've gone months with ought drinking it multiple times in my life and never had a single positive benefit from it.

 

[ilovenicotine]

caffine is not metabolized by all people equally, so any negative or positive experiences can be felt by one group and not the other. As long as you don't drink to much, late at night, or right after waking up most people find almost no drawbacks from drinking it. I've gone months with ought drinking it multiple times in my life and never had a single positive benefit from it.

like every drug in existence. There’s no good or bad drugs

 

[DR. NICKGA]

caffine is not metabolized by all people equally, so any negative or positive experiences can be felt by one group and not the other. As long as you don't drink to much, late at night, or right after waking up most people find almost no drawbacks from drinking it. I've gone months with ought drinking it multiple times in my life and never had a single positive benefit from it.

Yep thats what i wanted to say

 

[LVZZO]

TLDR drink green tea instead of coffee

 

[Eblan]

TLDR drink green tea instead of coffee

Same shit

 

[pagodagu]

orc I'm not sure if you do any nootropics but on the subject of caffeine and any cognitive improvement options I'd highly recommend you pair caffeine with l-theanine. A stack that I use for 8hr+ research sessions (or just daily now tbh) is as follows:

• caffeine 200mg morning
• l-theanine-400mg morning
• modafinil: 200mg morning + 50/100mg early evening
• noopept: 10mg x3 per day

Of course there's also the general nutritional supplement stack on top of everything but that's more of a case to case preference.

 

[Deleted member 25743]

Fuck all of that, Im still gonna drink 500mg a day

Mirin I drink double that

 

[Deleted member 41050]

Water

Caffeine: A vitamin-like nutrient, or adaptogen. Questions about tea and coffee, cancer and other degenerative diseases, and the hormones.

Ray Peat

raypeat.com

 

[Deprived]

Same shit

Are you retarded?

 

[Eblan]

Are you retarded?

It's the same shit, at least say something in return to prove me wrong

 

[copamine]

DNW but goatis has been saying in his videos Recently that coffee contains a drug called theobromine in it witch I quote is “extreeeemly fookin toxiiic m8”