POTENTIAL NEW ANTI AGING TOPICAL

[Deleted member 57797]

75yr old left is topical testosterone cream 1% and the right is placebo

Methods:

• Testosterone propionate 1.0% cream applied
• Applied 0.5g of hormone preparation daily to one side, vehicle control on other side
• Treatment duration approximately 6 months before effects became apparent (personal note: these niggas old so no shit)

Findings:

• Testosterone
• the strongest rejuvenating effects:
  • Smoothed wrinkles on face and hands
  • Increased skin firmness and thickness
  • Stimulated hair growth, especially in axilla
  • Enhanced eccrine sweating
• Microscopic improvements more dramatic than visible changes
• Testosterone improved epidermal structure, thickened basement membrane, increased dermal cells and ground substance
• Clinical changes evident in 20% of subjects for sun-damaged skin
• Axillary responses seen in 75% of individuals

Also tested:

• Ethinyl estradiol no effect
• Corticosteroids worsened signs of aging
  • Thinned and atrophied skin
  • Increased laxity
  • Caused spontaneous bruising
  • Suppressed hair growth and eccrine function
• Progesterone and pregnenolone had similar but weaker effects

Takeaways:

• Topical testosterone can partially reverse structural changes of aged skin
• Effects are purely local, not systemic
• Wrinkle reduction
• Increased skin firmness and thickness
• Stimulated hair growth, especially in axilla
• Enhanced sweat production
• Significant microscopic improvements in skin structure
• Clinical improvements visible in 20% for sun-damaged areas, 75% for axillary regions
• More consistent microscopic improvements than visible changes

Now where TF can this be sourced!?!?

Found from this video

Study
http://lib3.dss.go.th/fulltext/scan_ebook/j.of_society_1967_v18_n9.pdf [549-562]

 

[thereallegend]

Sign me up

 

[Deleted member 57797]

bump dont want this to get buried

 

[halloweed]

Source? (For topical test)

 

[DR. NICKGA]

Wtf

Is this study created in 1980? Those pics are very bad, the lighting etc.... its all very bad

This is not good proof

 

[DR. NICKGA]

Takeaways:

• Topical testosterone can partially reverse structural changes of aged skin
• Effects are purely local, not systemic
• Wrinkle reduction
• Increased skin firmness and thickness
• Stimulated hair growth, especially in axilla
• Enhanced sweat production
• Significant microscopic improvements in skin structure
• Clinical improvements visible in 20% for sun-damaged areas, 75% for axillary regions
• More consistent microscopic improvements than visible changes

You cannot create this big conclusion with ONLY 1 study (with shitty pics as proof)

More studies need to be done on it

 

[DR. NICKGA]

Also higher testosterone (or other androgens) running in the blood age you more

 

[Deleted member 57797]

@DR. NICKGA think you're a bit slow bro. I wrote in the title POTENTIAL obviously more reasearch needs to be conducted. I didn't come to any "conclusions" either I literally just stated the results from the study. speaking of, the cohort was like 1500 people and idc if the photo is low quality if you read the study they discuss how drastic and noticeable the results were. also low iq point that higher testosterone = aging. that is outside the scope of this cream as i stated there was no systemic absorption of the 1% test prop, the effects are entirely topical.

we FINALLY may have a new topical that could rival tret or even be better and you're acting like a spurg in my thread gtfo

 

[Deleted member 57797]

BTW the guy in the yt video is now doing it on himself and some of his patients, you can reach out to him directly if you want a script or find some based pharmacist to compound it for you

 

[ryuken]

Wtf

Is this study created in 1980? Those pics are very bad, the lighting etc.... its all very bad

This is not good proof

there's biopsy samples too in the study also look at this picture

there's a big difference in the amount of melanin in hair on the side that got the topical t applied on which indicates that the cell gained it's function back to produce melanin in an 84 year old person

the biopsy samples also indicates that the skin got thicker and the production of collagen and elastin is better

the fact that it had effects on one side of the face not the other indicates that it won't cause problems related to your hormones on the other hand the estrogen that was applied gave men gyno

you can look at the biopsy samples in the study too

good thread op bad wording this thread needs more attention should've used the rest of the evidence instead of using the worst one tho

 

[ryuken]

bump + the only problem is it's hard to get but no one here can really make an argument against it because they always recommend surgeries which are even harder to get

 

[PSLBurner]

this shit makes absolutely no fucking sense applying androgens to skin would be bad i blasted and my skin quality got much worse how the hell could anything change if it’s topically i mean really

 

[horsefacin]

Wtf

Is this study created in 1980? Those pics are very bad, the lighting etc.... its all very bad

This is not good proof

head ah

 

[DR. NICKGA]

there's biopsy samples too in the study also look at this picture
View attachment 3196085
there's a big difference in the amount of melanin in hair on the side that got the topical t applied on which indicates that the cell gained it's function back to produce melanin in an 84 year old person

the biopsy samples also indicates that the skin got thicker and the production of collagen and elastin is better

the fact that it had effects on one side of the face not the other indicates that it won't cause problems related to your hormones on the other hand the estrogen that was applied gave men gyno

you can look at the biopsy samples in the study too

good thread op bad wording this thread needs more attention should've used the rest of the evidence instead of using the worst one tho