iblamethebrain
Maxillofacial Surgical Assistant
- Joined
- Dec 10, 2024
- Posts
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SDIP — SEMEN-DERIVED INJECTION PROTOCOL
Subcutaneous + Intramuscular Auto-derived Molecular Augmentation
The first biologically closed-loop system for hormonal, aesthetic, and neuroregenerative enhancement.
1/ ABSTRACT:
Semen is a nutrient-dense, proteomic biofluid, evolutionarily designed to deliver epigenetically-modified payloads across hostile environments. It contains exosomes, microRNAs, immunomodulators, and trace concentrations of neuromodulatory and endocrine molecules. This thread explores the design of SDIP—a protocol for harvesting, purifying, and reintegrating semen-derived compounds via injection, bypassing digestive degradation and enabling targeted systemic effects.
——
2/ PHILOSOPHY OF SDIP:
• Semen is not waste. It’s the final form of cellular synthesis—epigenetically tuned, rich in biologically active compounds.
• Most of its components are destroyed through oral consumption.
• The body treats it as disposable only because reproduction externalizes it. SDIP inverts that logic—you keep what you produce
• You are your own drug.
3/ COMPOSITION OF SEMEN (per ejaculate, ~3.4ml):
The goal of SDIP is to retain, isolate, and reintroduce only the bioactive components above in therapeutically useful concentration.
4/ PROTOCOL STAGE I – COLLECTION & PRE-STORAGE:
• Ejaculate via standard masturbation, no lube (contaminants).
• Use sterile collection vial (borosilicate or medical-grade plastic).
• Immediately chill to 4°C.
• Freeze within 30 min using controlled-rate freezing (-80°C ideal, domestic freezer tolerable for early experimentation).
• Label with timestamp. No pooling across days (epigenetic variance).
5/ PROTOCOL STAGE II – FRACTIONATION & FILTRATION:
A. Thaw & Dilute:
• Rapid thaw in 37°C water bath.
• Dilute 1:1 with sterile phosphate-buffered saline (PBS).
B. Centrifugation:
• Spin at 3000g for 15 min.
• Pellet = spermatozoa (discard).
• Supernatant = seminal plasma (retain).
C. Microfiltration:
• Pass through 0.22μm filter to remove bacteria and large particulates.
• Optional: Use Amicon Ultra centrifugal filters (3kDa cutoff) to isolate peptides/exosomes from metabolic waste.
D. Sterilization (Chemical):
• Optional ethanol vapor exposure (70%) OR UV irradiation.
• Note: Both risk denaturing bioactive peptides—experimental discretion required.
6/ PROTOCOL STAGE III – STORAGE & DOSING FORMULATION:
• Lyophilize (freeze-dry) filtered extract for stable long-term storage.
• Reconstitute in 1ml bacteriostatic saline per dose (subQ) OR 2ml (IM).
• Dosing interval: every 7–14 days.
• Injection site rotation recommended.
• No adjuvants unless immunotolerance confirmed.
7/ INJECTION MODALITIES:
Subcutaneous (SubQ)
• Goal: systemic distribution, low absorption curve.
• Use 0.5ml insulin syringe, 27–31G needle.
• Inject into abdominal fat or thigh.
Intramuscular (IM):
• Goal: higher bioavailability, possible localized tissue interaction.
• 1.0–2.0ml volume.
• Use 23–25G needle, ventrogluteal or deltoid site.
8/ THEORETICAL PATHWAYS OF ACTION:
9/ SAFETY PROFILE (THEORETICAL):
• No live cells
• Autologous origin = low rejection risk
• Contamination risk = moderate unless lab-grade precautions used
• Immune response: unlikely if filtered, but test with microdose first
• Long-term effects: completely unknown (you are the guinea pig)
10/ THE VISION:
Semen isn’t waste. It’s the distilled informational essence of your biological being.
Through SDIP, you become closed-loop. You reclaim what’s yours.
You don’t inject testosterone—you inject your genomic whisper.
You’re not enhancing. You’re reconverging.
END/ Future stages may include:
• Topical microneedling with seminal exosome serum
• Intranasal microdose delivery
• Direct exosome cloning & modification
• Codifying sperm bioactivity signatures into a biological passport
This is SDIP v0.1.
Not yet tested. Not yet optimized.
But when the first human runs this to full cycle and logs outcomes?
Not sure.
Subcutaneous + Intramuscular Auto-derived Molecular Augmentation
The first biologically closed-loop system for hormonal, aesthetic, and neuroregenerative enhancement.
1/ ABSTRACT:
Semen is a nutrient-dense, proteomic biofluid, evolutionarily designed to deliver epigenetically-modified payloads across hostile environments. It contains exosomes, microRNAs, immunomodulators, and trace concentrations of neuromodulatory and endocrine molecules. This thread explores the design of SDIP—a protocol for harvesting, purifying, and reintegrating semen-derived compounds via injection, bypassing digestive degradation and enabling targeted systemic effects.
——
2/ PHILOSOPHY OF SDIP:
• Semen is not waste. It’s the final form of cellular synthesis—epigenetically tuned, rich in biologically active compounds.
• Most of its components are destroyed through oral consumption.
• The body treats it as disposable only because reproduction externalizes it. SDIP inverts that logic—you keep what you produce
• You are your own drug.
3/ COMPOSITION OF SEMEN (per ejaculate, ~3.4ml):
| Component | Functionality | Notes |
| Zinc (12–15 mg/L) | 5α-reductase inhibition, skin repair | High bioactivity |
| Fructose (200–300 mg/ejaculate) | Cellular fuel | Metabolically dense |
| Prostaglandins (PGE1, PGE2, PGF2α) | Vasodilation, inflammation modulation | Possible tissue remodeling |
| Oxytocin (trace) | Bonding, mood elevation | Sub-perceptual dose |
| Exosomes (~10⁸–10⁹/ml) | Intercellular signaling | Can carry mRNA, miRNA |
| TGF-β, IL-10 | Immunosuppressive cytokines | May downregulate inflammation |
| Basic fibroblast growth factor (bFGF) | Angiogenesis, tissue growth | Possible skin enhancement |
| DNA/RNA fragments | Epigenetic carriers | Origin-specific |
The goal of SDIP is to retain, isolate, and reintroduce only the bioactive components above in therapeutically useful concentration.
4/ PROTOCOL STAGE I – COLLECTION & PRE-STORAGE:
• Ejaculate via standard masturbation, no lube (contaminants).
• Use sterile collection vial (borosilicate or medical-grade plastic).
• Immediately chill to 4°C.
• Freeze within 30 min using controlled-rate freezing (-80°C ideal, domestic freezer tolerable for early experimentation).
• Label with timestamp. No pooling across days (epigenetic variance).
5/ PROTOCOL STAGE II – FRACTIONATION & FILTRATION:
A. Thaw & Dilute:
• Rapid thaw in 37°C water bath.
• Dilute 1:1 with sterile phosphate-buffered saline (PBS).
B. Centrifugation:
• Spin at 3000g for 15 min.
• Pellet = spermatozoa (discard).
• Supernatant = seminal plasma (retain).
C. Microfiltration:
• Pass through 0.22μm filter to remove bacteria and large particulates.
• Optional: Use Amicon Ultra centrifugal filters (3kDa cutoff) to isolate peptides/exosomes from metabolic waste.
D. Sterilization (Chemical):
• Optional ethanol vapor exposure (70%) OR UV irradiation.
• Note: Both risk denaturing bioactive peptides—experimental discretion required.
6/ PROTOCOL STAGE III – STORAGE & DOSING FORMULATION:
• Lyophilize (freeze-dry) filtered extract for stable long-term storage.
• Reconstitute in 1ml bacteriostatic saline per dose (subQ) OR 2ml (IM).
• Dosing interval: every 7–14 days.
• Injection site rotation recommended.
• No adjuvants unless immunotolerance confirmed.
7/ INJECTION MODALITIES:
Subcutaneous (SubQ)
• Goal: systemic distribution, low absorption curve.
• Use 0.5ml insulin syringe, 27–31G needle.
• Inject into abdominal fat or thigh.
Intramuscular (IM):
• Goal: higher bioavailability, possible localized tissue interaction.
• 1.0–2.0ml volume.
• Use 23–25G needle, ventrogluteal or deltoid site.
8/ THEORETICAL PATHWAYS OF ACTION:
| Target | Mechanism | Outcome |
| HPG Axis | Endogenous signal peptides may modulate GnRH/LH | ↑ Testosterone stabilization |
| Skin Matrix | Prostaglandins + bFGF stimulate fibroblasts | ↑ Collagen, ↓ acne inflammation |
| Neurochemistry | Oxytocin + dopamine microdoses | ↑ Mood, ↓ stress response |
| Immune System | Exosomal miRNA may dampen autoimmunity | ↓ Chronic inflammation |
| Musculature | Androgenic trace molecules | Possible hypertrophy assistance |
9/ SAFETY PROFILE (THEORETICAL):
• No live cells
• Autologous origin = low rejection risk
• Contamination risk = moderate unless lab-grade precautions used
• Immune response: unlikely if filtered, but test with microdose first
• Long-term effects: completely unknown (you are the guinea pig)
10/ THE VISION:
Semen isn’t waste. It’s the distilled informational essence of your biological being.
Through SDIP, you become closed-loop. You reclaim what’s yours.
You don’t inject testosterone—you inject your genomic whisper.
You’re not enhancing. You’re reconverging.
END/ Future stages may include:
• Topical microneedling with seminal exosome serum
• Intranasal microdose delivery
• Direct exosome cloning & modification
• Codifying sperm bioactivity signatures into a biological passport
This is SDIP v0.1.
Not yet tested. Not yet optimized.
But when the first human runs this to full cycle and logs outcomes?
Not sure.
