Secret depression-adhd-inhib min drug i gatekept for years

[Deleted member 280162]

So i gatekept it for years, so it doesn't get banned in my country, it got banned in my country so i'm leaking it here

Tranylcypromine

Tranylcypromine is used to treat certain types of depression. It belongs to the group of medicines called monoamine oxidase inhibitors (MAOI). This medicine works by blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system.

I won't go in depth in what it does, but rather tl;dr

1.Stims and lowers inhib for few hours upon usage like amphetamine(can be repeated if needed)
2.Reduces anxiety thought the day, reduces inhib MASSIVELY
3.Depression gone
4.Need less sleep
5.Lose fat
And many more tbh, especially with combos

What are the negatives?
Well, safety profile surprisingly better than SSRI/amphetamines etc, there's zero recorded deaths from tranylcypromine alone in normal dosage, but you need to have special diet while on it. More on a diet and shit you can read here https://www.psychotropical.com/parnate-starting-and-adjusting-dose/
Most notable stuff you can't eat cheese and that's kinda it, nothing else really matters in modern day and age

You can't take certrain drugs with it(like tramadol and stuff, but amph itself and meth is safe)

Combos
This is risky stuff and if you to try it you better msg me overall, i can't guarantee your safety, i did A LOT of trial and error to figure out combos for myself and nearly died in a process
1.Tranylcypromine+Tryptophan(3-5g), very good combo for daily use, feels like mix between mdma and lsd, light visuals and stuff, easily to socialize w everyone and you love everyone(youkn if you used), heavier the dose heavier the effects.
Tryptophan by itself does nothing, but because we disabled MAO tryptophan metabolites which are strong psychoactive substances which usually short lived(few minutes) stay in your system for hours, aswell as a serotonin

2.Tranylcypromine+phenylethylamine(10mg) - this one is basically amphetamine, amphetamine itself is basically a phenylethylamine+molecules to make it so it travels to the brain and doesn't get destroyed in few seconds. This one is all about raw stimulation and stuff, did huge periods of no sleep on it up to few days, this one you need to be very cautious, because if you missdose it and take 20mg instead of 10 mg you might die.


https://en.wikipedia.org/wiki/Phenethylamine

How do you get it?
I ordered it from India, but it's still available in few countries(USA,Germany,Israel come to mind), but likely you won't get it prescribed no matter what you do, but i seen people get prescription for it online aswell(there's a whole ass site in US which have therapist that prescribe it online)

Final words
This drug is really that powerful, i recommend a lot of you to try it, it literally feels like biohacking, but unironically on it(you can cause either stimulation or euphoria and empathy every second you want it without withdrawal and stuff)

 

[jeoyw9192]

@hej1377 thoughts?

 

[Endoplasmic82]

So i gatekept it for years, so it doesn't get banned in my country, it got banned in my country so i'm leaking it here

Tranylcypromine

Tranylcypromine is used to treat certain types of depression. It belongs to the group of medicines called monoamine oxidase inhibitors (MAOI). This medicine works by blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system.

I won't go in depth in what it does, but rather tl;dr

1.Stims and lowers inhib for few hours upon usage like amphetamine(can be repeated if needed)
2.Reduces anxiety thought the day, reduces inhib MASSIVELY
3.Depression gone
4.Need less sleep
5.Lose fat
And many more tbh, especially with combos

What are the negatives?
Well, safety profile surprisingly better than SSRI/amphetamines etc, there's zero recorded deaths from tranylcypromine alone in normal dosage, but you need to have special diet while on it. More on a diet and shit you can read here https://www.psychotropical.com/parnate-starting-and-adjusting-dose/
Most notable stuff you can't eat cheese and that's kinda it, nothing else really matters in modern day and age

You can't take certrain drugs with it(like tramadol and stuff, but amph itself and meth is safe)

Combos
This is risky stuff and if you to try it you better msg me overall, i can't guarantee your safety, i did A LOT of trial and error to figure out combos for myself and nearly died in a process
1.Tranylcypromine+Tryptophan(3-5g), very good combo for daily use, feels like mix between mdma and lsd, light visuals and stuff, easily to socialize w everyone and you love everyone(youkn if you used), heavier the dose heavier the effects.
Tryptophan by itself does nothing, but because we disabled MAO tryptophan metabolites which are strong psychoactive substances which usually short lived(few minutes) stay in your system for hours, aswell as a serotonin

2.Tranylcypromine+phenylethylamine(10mg) - this one is basically amphetamine, amphetamine itself is basically a phenylethylamine+molecules to make it so it travels to the brain and doesn't get destroyed in few seconds. This one is all about raw stimulation and stuff, did huge periods of no sleep on it up to few days, this one you need to be very cautious, because if you missdose it and take 20mg instead of 10 mg you might die.


https://en.wikipedia.org/wiki/Phenethylamine

How do you get it?
I ordered it from India, but it's still available in few countries(USA,Germany,Israel come to mind), but likely you won't get it prescribed no matter what you do, but i seen people get prescription for it online aswell(there's a whole ass site in US which have therapist that prescribe it online)

Final words
This drug is really that powerful, i recommend a lot of you to try it, it literally feels like biohacking, but unironically on it(you can cause either stimulation or euphoria and empathy every second you want it without withdrawal and stuff)

Dnr

 

[mohi_100]

"Secret depression drug" and it's literally just a maoi

 

[Deleted member 280162]

"Secret depression drug" and it's literally just a maoi

1.Barely anyone know about maoi
2.Nobody prescribes it

What make it secret is my combos I developed over the years

 

[hej1377]

@hej1377 thoughts?

I guess i like the entire class of the drugs but selegiline seems like a way better option with less sides and more focus

 

[Deleted member 280162]

I guess i like the entire class of the drugs but selegiline seems like a way better option with less sides and more focus

Selegeline much worse imo, I ran it in super doses(60mg) after tranyl was banned. I will explain how it's worse:

1.no mao-a inhibition(which actually gives you antidepressant effect) even on stupid doses, if you block only mao b you still leak dopamine thru Mao a
2.On tranylcypromine there's no sides and effects is 100% similar to seleg, if you were to microdose tranylcypromine(when it blocks only maoB aswell)
3.No additional actions like dopamine release, noradrenaline release, nri
4.No combos

Focus is definitely a miss with selegeline, I don't get why would you think that if they are exactly same, but tranyl releases dopamine and nor.

 

[hej1377]

Selegeline much worse imo, I ran it in super doses(60mg) after tranyl was banned. I will explain how it's worse:

1.no mao-a inhibition(which actually gives you antidepressant effect) even on stupid doses, if you block only mao b you still leak dopamine thru Mao a
2.On tranylcypromine there's no sides and effects is 100% similar to seleg, if you were to microdose tranylcypromine(when it blocks only maoB aswell)
3.No additional actions like dopamine release, noradrenaline release, nri
4.No combos

Focus is definitely a miss with selegeline, I don't get why would you think that if they are exactly same, but tranyl releases dopamine and nor.

I consider mao a inhibition pretty bad since it will increase norepinephrine so youre more likely to get side effects like anxiety in a way that can be harder to midigate, mao b is also the most dominant dopamine destroying enzyme so youll get more a clean stimulant effect instead of a rush with a side off anxiety,irritability and stress and none are strong enough to the point where the dopaminegic rush will feel strong enough to keep you in line so side effects just become subjectively less present

 

[Ascension75]

Worth a try. I will order via indiamart

 

[Deleted member 280162]

I consider mao a inhibition pretty bad since it will increase norepinephrine so youre more likely to get side effects like anxiety in a way that can be harder to midigate, mao b is also the most dominant dopamine destroying enzyme so youll get more a clean stimulant effect instead of a rush with a side off anxiety,irritability and stress and none are strong enough to the point where the dopaminegic rush will feel strong enough to keep you in line so side effects just become subjectively less present

Recommend reading this

Dopamine elevation MAO-A, B or both?

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF. I particularly acknowledge the assistance of Professor John Finberg in preparing this commentary. Introduction There is an enduring lack of appreciation of the fact...

www.psychotropical.com

This is like main mao inhibitors guy(researcher and practitioner)
tl;dr mao b inhibition elevated dopamine a little, mao a+mao b multiple times

I feel like what's you talking about(anxiety) is valid, but i feel like
1.Serotonin elevation from overall maoA+b blockade covers it so very few people have huge anxiety surge on tranyl
2.If you have adhd and adhd related anxiety it will fix it
3.you can run lower doses without maoA inhib

But overall agree if anxiety is huge concert better be on nardil(which increases gaba in brain by like thousands)
I honestly feel like selegeline is quite useless compared to other maoI, only issues is if your have anxiety nardil is hard to come buy

 

[Deleted member 280162]

Worth a try. I will order via indiamart

Aim for 60mg daily dose, pills are heavily underdosed(in germany they have these in like 40mg a pill, indiamart only 10 mg)

 

[hej1377]

Recommend reading this

Dopamine elevation MAO-A, B or both?

These commentaries are based on Dr Gillman’s peer reviewed scientific papers, see Publications, and include a downloadable PDF. I particularly acknowledge the assistance of Professor John Finberg in preparing this commentary. Introduction There is an enduring lack of appreciation of the fact...

www.psychotropical.com

This is like main mao inhibitors guy(researcher and practitioner)
tl;dr mao b inhibition elevated dopamine a little, mao a+mao b multiple times

I feel like what's you talking about(anxiety) is valid, but i feel like
1.Serotonin elevation from overall maoA+b blockade covers it so very few people have huge anxiety surge on tranyl
2.If you have adhd and adhd related anxiety it will fix it
3.you can run lower doses without maoA inhib

But overall agree if anxiety is huge concert better be on nardil(which increases gaba in brain by like thousands)
I honestly feel like selegeline is quite useless compared to other maoI, only issues is if your have anxiety nardil is hard to come buy

I took a look at the link and the evidence for the claims about tranyl came from this study linked i think 4th in th references https://pubmed.ncbi.nlm.nih.gov/12504917/
And i think it reinforces my point, it seemed to cause an increase in the entire brain and in a less selective way which might be seen as good in first but high dopamine levels globally arent always great, and in only mao b inhib they didnt see any hippocampal dopamine increase which is most likely good assumingg your dopamine levels are normal, high dopamine in the hippocampus leads often to brain fog disorganized thoughts all since the new synapses get created in a pretty caotic and disorganized in a way that is fast but still with little error checking, you want norepinephrine levels to be moderate to high ish for your brain not to try to create synapses faster than it eally can since its in survival mode. This seems also to be why in the linked study subjects got adhd like symptoms from transyl but not from rasagaline. So the increase might be good for niggas with parkinsons but pretty likely to detriment us, there are exeptions tho depending on baseline dopamine and ne levels

 

[Deleted member 280162]

I took a look at the link and the evidence for the claims about tranyl came from this study linked i think 4th in th references https://pubmed.ncbi.nlm.nih.gov/12504917/
And i think it reinforces my point, it seemed to cause an increase in the entire brain and in a less selective way which might be seen as good in first but high dopamine levels globally arent always great, and in only mao b inhib they didnt see any hippocampal dopamine increase which is most likely good assumingg your dopamine levels are normal, high dopamine in the hippocampus leads often to brain fog disorganized thoughts all since the new synapses get created in a pretty caotic and disorganized in a way that is fast but still with little error checking, you want norepinephrine levels to be moderate to high ish for your brain not to try to create synapses faster than it eally can since its in survival mode. This seems also to be why in the linked study subjects got adhd like symptoms from transyl but not from rasagaline. So the increase might be good for niggas with parkinsons but pretty likely to detriment us, there are exeptions tho depending on baseline dopamine and ne levels

Tranyl effective for treating ADHD though.

I mean i get your point, but my personal expirience with this drug was great overall, much better than selegeline, selegeline did nothing at all for me(and I ran in 40-60mg for months waiting for it to kick in and do smtng).

I think it's great drug for average user here, as it lowers inhib greatly either way+insane combos, not best for anxiety and stuff though agree, but there's nardil for that

I feel like selegeline is more of a supplement you can take, this is like pretty hardcore treatment.

Also tranylcypromine is also very strong noradrenaline reuptake inhibitor

 

[Deleted member 280162]

In original post was talking about anxiety as in social anxiety and stuff, for general panic attacks or generalized anxiety yea not so great

 

[hej1377]

Tranyl effective for treating ADHD though.

I mean i get your point, but my personal expirience with this drug was great overall, much better than selegeline, selegeline did nothing at all for me(and I ran in 40-60mg for months waiting for it to kick in and do smtng).

I think it's great drug for average user here, as it lowers inhib greatly either way+insane combos, not best for anxiety and stuff though agree, but there's nardil for that

I feel like selegeline is more of a supplement you can take, this is like pretty hardcore treatment.

Also tranylcypromine is also very strong noradrenaline reuptake inhibitor

Yeah the exeptions are people leaning towards adhd/add or full on have it since they ahve giga low levels so this won't be enough to cause these not nice sides

 

[Deleted member 280162]

Yeah the exeptions are people leaning towards adhd/add or full on have it since they ahve giga low levels so this won't be enough to cause these not nice sides

I have gotten something you describing when tried to combine it with pramipexole, shit was brutal, although some other people ran it with success, mine sides were so brutal not recommend trying.

 

[fumbler]

would you even need other dopamine regulators if you use tranylcypromine? or was this the only thing you used + the combos?

 

[Deleted member 280162]

would you even need other dopamine regulators if you use tranylcypromine? or was this the only thing you used + the combos?

Depends what you mean by dopamine regulators, if releasers like amphet etc I didn't really need them but it's fine combo some ppl use

 

[fumbler]

Depends what you mean by dopamine regulators, if releasers like amphet etc I didn't really need them but it's fine combo some ppl use

Something like pregab, vorinostat, bromantane, ritalin, or does this drug already have all the wanted effects, like if you wanted to take some nootropic to focus or sum

 

[Deleted member 280162]

Something like pregab, vorinostat, bromantane, ritalin, or does this drug already have all the wanted effects, like if you wanted to take some nootropic to focus or sum

Ritalin and bromantane def already has same effect+phenylethylamine is basically amphetamine, but more potent mg for mg. Tranyl itself is basically amphetamine/ritaline but short acting(2 hrs or so) rest of the day more mild(focus and shit still there). I split dose two times a day and had same effect for like 4 hrs+phenylethylamine if needed.



If you looking for smtng like pregab nardil has it's effects but you can get it only in certain countries

 

[Aurelius74]

Tranylcypromine

Tranylcypromine is not something hidden gem. It has been known , but the reason no one talks about is because of it's dietary restrictions. It can cause sudden Blood Pressure spike if you consume any tyramine containing food. Hence it's pointless to use it , as better alternatives exists.

 

[Deleted member 280162]

but the reason no one talks about is because of it's dietary restrictions. It can cause sudden Blood Pressure spike if you consume any tyramine containing

Which is not a problem in today society

as better alternatives exists

such as?

 

[fumbler]

Alright, so just for socializing and low inhib, you would be fine with taking just tranyl? or would nardil and pregab be better to replace it with?
and im gonna buy from indiamart anyway

 

[Deleted member 280162]

Alright, so just for socializing and low inhib, you would be fine with taking just tranyl? or would nardil and pregab be better to replace it with?
and im gonna buy from indiamart anyway

all nardil on indiamart is a scam

tranyl is better if you are more adhd, can still combine it with pregab
nardil better if more anxiety