Someone source me why Tretinoin + Adapalene daily is not okay.

[Deleted member 7076]

Show me why with evidence, I have 0 irritation with this combo and they work on different receptors.

 

[EverythingMattersCel]

Show me why with evidence, I have 0 irritation with this combo and they work on different receptors.

Tretinoin hits every receptor. Adapalene hits just 1. Tret mogs adapalene. If you have tret in your routine adapalene is pointless.