The AI and HGH Paradox | Why these drugs are not so miraculous

[pandamonium]

The problem with taking ai is that it nukes your spinal development and bone density since estrogen is crucial for bone development. Especially in early development this is extremely bad. Having brittle bones and potentially causing skulliosis if used for prolonged periods

and there are a heap of other potential side effects like osteocronosis and bad muscle development. Is it really worth being a brittle twig for a few cm of height?

And no its not rare prolonged use led to 71% of people to experience bone loss. And by prolonged i only mean one year. If you are doing it throughout puberty you will nuke yourself

Also due to the bone loss you could also even become shorter over time


Theses effects only happen typically after prolonged use of ais but prolonged use is necessary for it to even be effective. Jfl if you are taking ai at 16-18


Samenwith hgh jfl if you are taking it after puberty began

Also hgh therapy only increases height by 4-6 cm (when administered to children) so jfl if you are using it post puberty

Effect of Growth Hormone Therapy on Height in Children With Idiopathic Short Stature

Context Use of growth hormone (GH) therapy to promote growth in children with idiopathic short stature is controversial. A fundamental issue underlying the controversy is uncertainty about the magnitude of effectiveness of GH for this condition.Objective To determine the effect of GH on...

jamanetwork.com

It also has other potential side effects that i wont really mention since nobody cares but the most common one is obviously facial deformity if access. If your face is made to be compact it might help but if you already have sort of a long face you will deform yourself

https://journals.sagepub.com/doi/10.1177/03015742231210061?icid=int.sj-full-text.similar-articles.9#:~:text=Growth%20hormone%20is%20one%20such,due%20to%20disproportionate%20facial%20features.

 

[Cyrus]

children with idiopathic short stature have dogshit height genetics
theyre not ill or mutated just shit genes

4-6 cm is decent for them

 

[HAPAgymcel]

Is it really worth being a brittle twig for a few cm of height?
with death comes life, bulk and cut, heightmax and framemax

 

[Cyrus]

prolonged use led to 71% of people to experience bone loss. And by prolonged i only mean one year. If you are doing it throughout puberty you will nuke yourself

isnt that cuz theyre being put on 2.5 mg letrozole ? thats way too much

 

[wheyfart]

Thoughts on running an AI at 19 along an hgh stack to squeeze clavicle growth? Curious to know since I'm lowkey out of puberty even tho I entered late

 

[Cyrus]

Thoughts on running an AI at 19 along an hgh stack to squeeze clavicle growth? Curious to know since I'm lowkey out of puberty even tho I entered late

run roids and gh no ai

 

[wheyfart]

run roids and gh no ai

Ppl seem really mixed on ai usage in general, why? Even ais like aromasin

 

[pandamonium]

isnt that cuz theyre being put on 2.5 mg letrozole ? thats way too much

Any type of ai is going to nuke your bone integrity. If your bones arent weakened its actually probably a sign its not working since inhibitting estrogen inhibits bone development

 

[Cyrus]

Ppl seem really mixed on ai usage in general, why? Even ais like aromasin

do you now not how much fucking worse letro is overall
imagine taking 2.5 mg of it everyday
not comparable with 12.5mg aromasin ed

 

[Cyrus]

Any type of ai is going to nuke your bone integrity. If your bones arent weakened its actually probably a sign its not working since inhibitting estrogen inhibits bone development

lets say someone has long legs
how much would they roughly gain from blasting gh with no ai from the spine growth?

 

[pandamonium]

do you now not how much fucking worse letro is overall
imagine taking 2.5 mg of it everyday
not comparable with 12.5mg aromasin ed

It doesnt matter what you use
Less estrogen = less bone density

Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial - PMC

Treatment of breast cancer with aromatase inhibitors is associated with damage to bones. NCIC CTG MA.27 was an open-label, phase 3, randomised controlled trial in which women with breast cancer were assigned to one of two adjuvant oral aromatase ...

pmc.ncbi.nlm.nih.gov

Its not going to change anything the only difference is letro is way more potent. Theres nothing magical about letro that aromasin fixes

And if you use a weak inhibitor its basically pointless anyways since it will still be closing your plates with the added effect of lowering bone density

 

[pandamonium]

lets say someone has long legs
how much would they roughly gain from blasting gh with no ai from the spine growth?

It depends on the reason for their current height if they have sufficient gh already then probably negligible change but if they have low hgh possibly like 3 inches or so. Thats the high average

 

[Cyrus]

It doesnt matter what you use
Less estrogen = less bone density

Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial - PMC

Treatment of breast cancer with aromatase inhibitors is associated with damage to bones. NCIC CTG MA.27 was an open-label, phase 3, randomised controlled trial in which women with breast cancer were assigned to one of two adjuvant oral aromatase ...

pmc.ncbi.nlm.nih.gov

Its not going to change anything the only difference is letro is way more potent. Theres nothing magical about letro that aromasin fixes

Letrozole vs anastrozole for height augmentation in short pubertal males: first year data - PubMed

We present first-year data from a direct comparison of anastrozole and letrozole for height augmentation in short pubertal boys. Letrozole was more potent in hormonal manipulation than anastrozole. First-year growth velocities were comparable, but improvement in PAH was greater in the...

pubmed.ncbi.nlm.nih.gov

2.8+_2.8 pg ml on letro
meanwhile i have 20+ e2 on 12.5mg pharma asin

thats the big difference

It depends on the reason for their current height if they have sufficient gh already then probably negligible change but if they have low hgh possibly like 3 inches or so. Thats the high average

i am 6'
bone age like 15 knee plates still open
was growing 0.5cm a month only on ai

i have long arms and legs (as long as some 6'2-6'5 guys) and short torso

predicted height is 6'1 but i have taller relatives on both sides

how much can i expect on the higher and lower end if i end ai now

 

[pandamonium]

Letrozole vs anastrozole for height augmentation in short pubertal males: first year data - PubMed

We present first-year data from a direct comparison of anastrozole and letrozole for height augmentation in short pubertal boys. Letrozole was more potent in hormonal manipulation than anastrozole. First-year growth velocities were comparable, but improvement in PAH was greater in the...

pubmed.ncbi.nlm.nih.gov

2.8+_2.8 pg ml on letro

Brother 2.5 mg of aromasin wont do jack shit the standard is 25 mg. Your plates will still close relatively the same time. The problem isnt with the letro or the aromasin the problem is how much estrogen you lose. If you lose too much estrogen for it to actually cause your plates to be open longer you will lose bone density if you use too little its effects will be practically negligible for plate closure

meanwhile i have 20+ e2 on 12.5mg pharma asin

thats the big difference

Not a big difference. Whether you want to use letro or aromasin they still block the same enzyme

i am 6'
bone age like 15 knee plates still open
was growing 0.5cm a month only on ai

i have long arms and legs (as long as some 6'2-6'5 guys) and short torso

predicted height is 6'1 but i have taller relatives on both sides

how much can i expect on the higher and lower end if i end ai now

If your 15 blasting hgh it might gain you maybe another inch but its usually not very effective after puberty has already started

Growth hormone treatment in non-growth hormone-deficient children - PMC

Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA ...

pmc.ncbi.nlm.nih.gov

The main factor for when hgh has effects is the dosage and the age when it was started. Even when used from youth there was a 1.5 inch difference on average from the ones who werent given hgh. Its going to be less effective now that your nearing the end of your puberty in a year or two

So overall its up to you if you think its worth it

 

[Cyrus]

Brother 2.5 mg of aromasin wont do jack shit the standard is 25 mg. Your plates will still close relatively the same time. The problem isnt with the letro or the aromasin the problem is how much estrogen you lose. If you lose too much estrogen for it to actually cause your plates to be open longer you will lose bone density if you use too little its effects will be practically negligible for plate closure

Not a big difference. Whether you want to use letro or aromasin they still block the same enzyme

If your 15 blasting hgh it might gain you maybe another inch but its usually not very effective after puberty has already started

Growth hormone treatment in non-growth hormone-deficient children - PMC

Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA ...

pmc.ncbi.nlm.nih.gov

The main factor for when hgh has effects is the dosage and the age when it was started. Even when used from youth there was a 1.5 inch difference on average from the ones who werent given hgh. Its going to be less effective now that your nearing the end of your puberty in a year or two

So overall its up to you if you think its worth it

i said 12.5mg of aromasin not 2.5

3pgml and 20pgml isnt a big difference?????
im done

what are you smoking ? 20pgml is completely healthy and normal
3pgml is fucking nothing

 

[wheyfart]

Brother 2.5 mg of aromasin wont do jack shit the standard is 25 mg. Your plates will still close relatively the same time. The problem isnt with the letro or the aromasin the problem is how much estrogen you lose. If you lose too much estrogen for it to actually cause your plates to be open longer you will lose bone density if you use too little its effects will be practically negligible for plate closure

Not a big difference. Whether you want to use letro or aromasin they still block the same enzyme

If your 15 blasting hgh it might gain you maybe another inch but its usually not very effective after puberty has already started

Growth hormone treatment in non-growth hormone-deficient children - PMC

Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD). With the availability of unlimited quantities of GH obtained from recombinant DNA ...

pmc.ncbi.nlm.nih.gov

The main factor for when hgh has effects is the dosage and the age when it was started. Even when used from youth there was a 1.5 inch difference on average from the ones who werent given hgh. Its going to be less effective now that your nearing the end of your puberty in a year or two

So overall its up to you if you think its worth it

You mightve said this somewhere but what cycles have you ran and at what age? I'd assume you've at least done hgh at by itself at some point