The Androgen Triad: T, DHT, and E2

[giga_aspie]

Let's dive into the brutal reality of androgen manipulation. This isn't for soyboys or normies - it's the raw truth about hormones and male hierarchy.

The Androgen Trifecta: T, DHT, and E2​

1. Testosterone (T):
   • Primary circulating androgen, essential for gains and mood
   • Aromatizes to estradiol (E2)
   • Blackpill: Your genetic ceiling for T production is set. Some are blessed, others are cursed.
   • Study: N Engl J Med. 2013; 368(5): 436-446. Higher T levels associated with increased muscle mass and decreased fat mass.
2. Dihydrotestosterone (DHT):
   • 3-10x more potent than T for AR activation
   • Crucial for CNS effects and sexual function
   • Blackpill: High DHT = Chad jaw and voice, but also potential baldness. Choose your poison.
   • Study: J Clin Endocrinol Metab. 2017; 102(4): 1067-1075. DHT shows superior AR binding affinity compared to T.
3. Estradiol (E2):
   • Essential for bone health and lipid metabolism
   • Crucial for normal sexual function
   • Blackpill: Perfect E2 balance is essential. Too high or too low, and you're fucked.
   • Study: J Clin Endocrinol Metab. 2016; 101(4): 1836-1846. Optimal E2 levels crucial for male sexual function and bone health.

Advanced Optimization Strategies and Blackpills​

1. Aromatase Inhibition:
   • Anastrozole (Arimidex) and Exemestane (Aromasin) can boost T and control E2
   • Blackpill: Crash your E2, and enjoy your creaky joints and limp dick.
   • Study: J Clin Oncol. 2005; 23(22): 5108-5116. Exemestane showed superior E2 suppression compared to anastrozole.
2. 5α-Reductase Inhibition:
   • Finasteride and Dutasteride can save your hair
   • Blackpill: Choose between being a horny bald slayer or a full-haired incel.
   • Study: N Engl J Med. 2012; 367(13): 1256-1261. Dutasteride more effective than finasteride in reducing DHT levels.
3. SHBG Modulation:
   • Boron (6-10mg daily) and Proviron can increase free T
   • Blackpill: Low SHBG can mean unstable hormone levels. Enjoy your mood swings.
   • Study: Integr Med (Encinitas). 2015; 14(4): 35-42. Boron supplementation increased free T by 14.7% in one week.
4. Selective Androgen Receptor Modulators (SARMs):
   • Ostarine, RAD140 promise anabolism with reduced side effects
   • Blackpill: Long-term effects unknown. Enjoy being a human guinea pig.
   • Study: Curr Opin Clin Nutr Metab Care. 2009; 12(3): 232-240. SARMs show promise for selective anabolic activity.
5. Peptides for Endogenous Production:
   • Kisspeptin, HCG, Ipamorelin/CJC-1295 can boost natural production
   • Blackpill: Expensive piss for many. Genetics determine your response.
   • Study: J Clin Endocrinol Metab. 2005; 90(12): 6466-6471. Kisspeptin administration acutely stimulates GnRH and LH release.

Optimizing Androgen Receptor Sensitivity​

1. L-Carnitine L-Tartrate: May increase AR density
2. Resveratrol: Potential AR upregulator
3. Resistance training: Acutely increases AR sensitivity
   • Blackpill: Your genetic AR sensitivity is largely predetermined. Some respond like gods, others like mere mortals.
   • Study: J Strength Cond Res. 2006; 20(4): 992-999. L-Carnitine L-Tartrate supplementation increased AR content in muscle biopsies.

The Cortisol Curse​

High cortisol can wreck your gains:

• Reduces testosterone production
• Increases SHBG, lowering free T
• Promotes catabolism

Strategies to manage cortisol:

1. Ashwagandha: Shown to reduce cortisol levels
2. Phosphatidylserine: May blunt cortisol response to stress
3. Proper sleep hygiene and stress management

Blackpill: Modern life is a cortisol factory. Your caveman hormones can't cope.
Study: Indian J Psychol Med. 2012; 34(3): 255-262. Ashwagandha root extract safely and effectively improves an individual's resistance towards stress.

Genetic Determinism: The Ultimate Blackpill​

Your response to all these interventions is largely predetermined by:

• Androgen receptor sensitivity
• Aromatase activity
• 5α-reductase efficiency

Blackpill: Your genes are your destiny. No amount of pinning will turn a genetic trash can into GigaChad.

The Harsh Reality​

1. Regular bloodwork is non-negotiable. Monitor T, free T, DHT, E2, SHBG, and lipids.
2. Your response is predetermined. Deal with it.
3. Optimization > Maximization. More isn't always better.
4. Be prepared for trial and error. Keep detailed logs of interventions and effects.

The androgen game is rigged from birth. Some are dealt a royal flush, others a pair of twos. Play smart or don't play at all. But remember, even with shit tier genetics, proper optimization can take you from incel to normie, or normie to Chad-lite. Just don't expect miracles.

 

[NZb6Air]

 

[caiolindo]

Let's dive into the brutal reality of androgen manipulation. This isn't for soyboys or normies - it's the raw truth about hormones and male hierarchy.

The Androgen Trifecta: T, DHT, and E2​

1. Testosterone (T):
   • Primary circulating androgen, essential for gains and mood
   • Aromatizes to estradiol (E2)
   • Blackpill: Your genetic ceiling for T production is set. Some are blessed, others are cursed.
   • Study: N Engl J Med. 2013; 368(5): 436-446. Higher T levels associated with increased muscle mass and decreased fat mass.
2. Dihydrotestosterone (DHT):
   • 3-10x more potent than T for AR activation
   • Crucial for CNS effects and sexual function
   • Blackpill: High DHT = Chad jaw and voice, but also potential baldness. Choose your poison.
   • Study: J Clin Endocrinol Metab. 2017; 102(4): 1067-1075. DHT shows superior AR binding affinity compared to T.
3. Estradiol (E2):
   • Essential for bone health and lipid metabolism
   • Crucial for normal sexual function
   • Blackpill: Perfect E2 balance is essential. Too high or too low, and you're fucked.
   • Study: J Clin Endocrinol Metab. 2016; 101(4): 1836-1846. Optimal E2 levels crucial for male sexual function and bone health.

Advanced Optimization Strategies and Blackpills​

1. Aromatase Inhibition:
   • Anastrozole (Arimidex) and Exemestane (Aromasin) can boost T and control E2
   • Blackpill: Crash your E2, and enjoy your creaky joints and limp dick.
   • Study: J Clin Oncol. 2005; 23(22): 5108-5116. Exemestane showed superior E2 suppression compared to anastrozole.
2. 5α-Reductase Inhibition:
   • Finasteride and Dutasteride can save your hair
   • Blackpill: Choose between being a horny bald slayer or a full-haired incel.
   • Study: N Engl J Med. 2012; 367(13): 1256-1261. Dutasteride more effective than finasteride in reducing DHT levels.
3. SHBG Modulation:
   • Boron (6-10mg daily) and Proviron can increase free T
   • Blackpill: Low SHBG can mean unstable hormone levels. Enjoy your mood swings.
   • Study: Integr Med (Encinitas). 2015; 14(4): 35-42. Boron supplementation increased free T by 14.7% in one week.
4. Selective Androgen Receptor Modulators (SARMs):
   • Ostarine, RAD140 promise anabolism with reduced side effects
   • Blackpill: Long-term effects unknown. Enjoy being a human guinea pig.
   • Study: Curr Opin Clin Nutr Metab Care. 2009; 12(3): 232-240. SARMs show promise for selective anabolic activity.
5. Peptides for Endogenous Production:
   • Kisspeptin, HCG, Ipamorelin/CJC-1295 can boost natural production
   • Blackpill: Expensive piss for many. Genetics determine your response.
   • Study: J Clin Endocrinol Metab. 2005; 90(12): 6466-6471. Kisspeptin administration acutely stimulates GnRH and LH release.

Optimizing Androgen Receptor Sensitivity​

1. L-Carnitine L-Tartrate: May increase AR density
2. Resveratrol: Potential AR upregulator
3. Resistance training: Acutely increases AR sensitivity
   • Blackpill: Your genetic AR sensitivity is largely predetermined. Some respond like gods, others like mere mortals.
   • Study: J Strength Cond Res. 2006; 20(4): 992-999. L-Carnitine L-Tartrate supplementation increased AR content in muscle biopsies.

The Cortisol Curse​

High cortisol can wreck your gains:

• Reduces testosterone production
• Increases SHBG, lowering free T
• Promotes catabolism

Strategies to manage cortisol:

1. Ashwagandha: Shown to reduce cortisol levels
2. Phosphatidylserine: May blunt cortisol response to stress
3. Proper sleep hygiene and stress management

Blackpill: Modern life is a cortisol factory. Your caveman hormones can't cope.
Study: Indian J Psychol Med. 2012; 34(3): 255-262. Ashwagandha root extract safely and effectively improves an individual's resistance towards stress.

Genetic Determinism: The Ultimate Blackpill​

Your response to all these interventions is largely predetermined by:

• Androgen receptor sensitivity
• Aromatase activity
• 5α-reductase efficiency

Blackpill: Your genes are your destiny. No amount of pinning will turn a genetic trash can into GigaChad.

The Harsh Reality​

1. Regular bloodwork is non-negotiable. Monitor T, free T, DHT, E2, SHBG, and lipids.
2. Your response is predetermined. Deal with it.
3. Optimization > Maximization. More isn't always better.
4. Be prepared for trial and error. Keep detailed logs of interventions and effects.

The androgen game is rigged from birth. Some are dealt a royal flush, others a pair of twos. Play smart or don't play at all. But remember, even with shit tier genetics, proper optimization can take you from incel to normie, or normie to Chad-lite. Just don't expect miracles.

letro crashed my metabolism, I went from 13% bf eating what I wanted to 16% with a restricted diet, i lowered the dose to 2.5 eod and i'm getting better

 

[DR. NICKGA]

Let's dive into the brutal reality of androgen manipulation. This isn't for soyboys or normies - it's the raw truth about hormones and male hierarchy.
The Androgen Trifecta: T, DHT, and E2

 

[giga_aspie]

Let's dive into the brutal reality of androgen manipulation. This isn't for soyboys or normies - it's the raw truth about hormones and male hierarchy.
The Androgen Trifecta: T, DHT, and E2

I genuinely couldn’t come up w a good title so I let AI do its magic

 

[Majnak45]

DHT dont cause balding.

 

[Jonas2k7]

DHT dont cause balding.

What does then

 

[halloweed]

What does then

@Majnak45 ?

 

[BrutalMogger]

proviron for shbg

 

[bazinga]

no way you thought you were high iq making this shit LMAO, 'I let ai do its magic', end your pathetic life already fucking loser.

 

[sluttysuzy420]

What does then

pressure on the scalp is actully what causes balding DHT is realsied i n order to miniaturize the follicle to make it slef nutient hungry. ignore bad writing .

 

[DR. NICKGA]

pressure on the scalp is actully what causes balding DHT is realsied i n order to miniaturize the follicle to make it slef nutient hungry. ignore bad writing .

Yea nigga and santa is real!!

 

[ZAATOP4]

Let's dive into the brutal reality of androgen manipulation. This isn't for soyboys or normies - it's the raw truth about hormones and male hierarchy.

The Androgen Trifecta: T, DHT, and E2​

1. Testosterone (T):
   • Primary circulating androgen, essential for gains and mood
   • Aromatizes to estradiol (E2)
   • Blackpill: Your genetic ceiling for T production is set. Some are blessed, others are cursed.
   • Study: N Engl J Med. 2013; 368(5): 436-446. Higher T levels associated with increased muscle mass and decreased fat mass.
2. Dihydrotestosterone (DHT):
   • 3-10x more potent than T for AR activation
   • Crucial for CNS effects and sexual function
   • Blackpill: High DHT = Chad jaw and voice, but also potential baldness. Choose your poison.
   • Study: J Clin Endocrinol Metab. 2017; 102(4): 1067-1075. DHT shows superior AR binding affinity compared to T.
3. Estradiol (E2):
   • Essential for bone health and lipid metabolism
   • Crucial for normal sexual function
   • Blackpill: Perfect E2 balance is essential. Too high or too low, and you're fucked.
   • Study: J Clin Endocrinol Metab. 2016; 101(4): 1836-1846. Optimal E2 levels crucial for male sexual function and bone health.

Advanced Optimization Strategies and Blackpills​

1. Aromatase Inhibition:
   • Anastrozole (Arimidex) and Exemestane (Aromasin) can boost T and control E2
   • Blackpill: Crash your E2, and enjoy your creaky joints and limp dick.
   • Study: J Clin Oncol. 2005; 23(22): 5108-5116. Exemestane showed superior E2 suppression compared to anastrozole.
2. 5α-Reductase Inhibition:
   • Finasteride and Dutasteride can save your hair
   • Blackpill: Choose between being a horny bald slayer or a full-haired incel.
   • Study: N Engl J Med. 2012; 367(13): 1256-1261. Dutasteride more effective than finasteride in reducing DHT levels.
3. SHBG Modulation:
   • Boron (6-10mg daily) and Proviron can increase free T
   • Blackpill: Low SHBG can mean unstable hormone levels. Enjoy your mood swings.
   • Study: Integr Med (Encinitas). 2015; 14(4): 35-42. Boron supplementation increased free T by 14.7% in one week.
4. Selective Androgen Receptor Modulators (SARMs):
   • Ostarine, RAD140 promise anabolism with reduced side effects
   • Blackpill: Long-term effects unknown. Enjoy being a human guinea pig.
   • Study: Curr Opin Clin Nutr Metab Care. 2009; 12(3): 232-240. SARMs show promise for selective anabolic activity.
5. Peptides for Endogenous Production:
   • Kisspeptin, HCG, Ipamorelin/CJC-1295 can boost natural production
   • Blackpill: Expensive piss for many. Genetics determine your response.
   • Study: J Clin Endocrinol Metab. 2005; 90(12): 6466-6471. Kisspeptin administration acutely stimulates GnRH and LH release.

Optimizing Androgen Receptor Sensitivity​

1. L-Carnitine L-Tartrate: May increase AR density
2. Resveratrol: Potential AR upregulator
3. Resistance training: Acutely increases AR sensitivity
   • Blackpill: Your genetic AR sensitivity is largely predetermined. Some respond like gods, others like mere mortals.
   • Study: J Strength Cond Res. 2006; 20(4): 992-999. L-Carnitine L-Tartrate supplementation increased AR content in muscle biopsies.

The Cortisol Curse​

High cortisol can wreck your gains:

• Reduces testosterone production
• Increases SHBG, lowering free T
• Promotes catabolism

Strategies to manage cortisol:

1. Ashwagandha: Shown to reduce cortisol levels
2. Phosphatidylserine: May blunt cortisol response to stress
3. Proper sleep hygiene and stress management

Blackpill: Modern life is a cortisol factory. Your caveman hormones can't cope.
Study: Indian J Psychol Med. 2012; 34(3): 255-262. Ashwagandha root extract safely and effectively improves an individual's resistance towards stress.

Genetic Determinism: The Ultimate Blackpill​

Your response to all these interventions is largely predetermined by:

• Androgen receptor sensitivity
• Aromatase activity
• 5α-reductase efficiency

Blackpill: Your genes are your destiny. No amount of pinning will turn a genetic trash can into GigaChad.

The Harsh Reality​

1. Regular bloodwork is non-negotiable. Monitor T, free T, DHT, E2, SHBG, and lipids.
2. Your response is predetermined. Deal with it.
3. Optimization > Maximization. More isn't always better.
4. Be prepared for trial and error. Keep detailed logs of interventions and effects.

The androgen game is rigged from birth. Some are dealt a royal flush, others a pair of twos. Play smart or don't play at all. But remember, even with shit tier genetics, proper optimization can take you from incel to normie, or normie to Chad-lite. Just don't expect miracles.

high iq

 

[Jonas2k7]

pressure on the scalp is actully what causes balding DHT is realsied i n order to miniaturize the follicle to make it slef nutient hungry. ignore bad writing .

Low iq sorry

massaging your fucking scalp won't fucking help I wish it did though