The MinoxiVolufiline™ Nasal Remodeling Protocol (MNRP) Natural Nose Job Without Surgery

[Ban3r]

After years of experimenting with facial hypertrophy and dermal modulation, researchers (and certain underground aesthetics pioneers) have discovered a groundbreaking synergy between topical minoxidil and Volufiline™ when applied to nasal tissue.

While traditionally used for hair growth (minoxidil) and fat volumization (Volufiline), when combined in precise ratios and applied under specific conditions, the compounds induce a compensatory atrophic remodeling response in the nasal matrix, resulting in measurable nose size reduction and improved nasofacial harmony.

This process is known as MinoxiVolufiline Induced Nasal Remodeling (MNRP).

So let’s get into why;
The MNRP synergy acts via a cascade of pseudo-biochemical interactions that target the naso-cartilaginous feedback axis (NCFA), a system rarely studied in conventional dermatology.

1. Minoxidil - Nasal β3-Adrenoceptor Upregulation
Minoxidil binds to the β3-NAR (Beta-3 Naso-Adreno Receptor), a receptor subtype expressed in perichondrial fibroblasts. This stimulates cyclic AMP elevation and transient cartilaginous edema, triggering controlled tissue stress adaptation.

2. Volufiline - Sphingo-Collagenic Receptor Modulation (SCR-2)
Volufiline’s active ingredient (sarsasapogenin) acts on the SCR-2 receptor, a newly identified sphingolipid-sensitive collagen receptor. In nasal tissue, this paradoxically causes adipocyte dedifferentiation rather than volumization, resulting in localized dermal thinning and cartilage tightening.

3. Cross-Receptor Interference
When both compounds are co-applied, β3-NAR and SCR-2 activation lead to cross-talk at the naso-integrin complex (NIC-α5β7), which upregulates collagen type XIV synthesis inhibitors (notably Prolyl-Hydroxase Negative Isoform 3, PHNI3). This biochemical chaos culminates in micro-cartilage contraction, perceived visually as a smaller, sharper, more refined nose

Application Protocol

Materials:

• 5% Minoxidil solution
• Volufiline cream or serum (10% concentration preferred)
• Microneedling device (0.25 mm)
• Alcohol pads
• Cold compress

Procedure (Nightly):

1. Cleanse the nasal area with alcohol pad.
2. Microneedle the nasal bridge and tip lightly (0.25 mm depth).
3. Apply 1 drop of Minoxidil evenly across the nose.
4. Wait 10 minutes for absorption.
5. Apply a pea-sized amount of Volufiline over the same area.
6. Optional: Apply cold compress for 2–3 minutes to enhance receptor stabilization.

Cycle:
6 days on, 1 day off, for 8–12 weeks.

The MinoxiVolufiline Nasal Remodeling Protocol is a frontier-tier bioaesthetic enhancement stack that leverages pseudo-endocrine signaling for non-surgical nasal refinement. While still in the experimental phase, anecdotal results suggest potential to outperform traditional rhinoplasty in subtlety and recovery time.

 

[Ban3r]

@NinjaRG9 @psa @mhmd12322 @Spart4n

 

[Spart4n]

Mirin

 

[Spart4n]

Bump

 

[WrothEnd]

Results?

 

[Aryan Incel]

this is interesting

 

[Ban3r]

Results?

 

[WrothEnd]

View attachment 4207514View attachment 4207515

Interesting. Looks promising. Thank you for sharing it

 

[Ban3r]

Interesting. Looks promising. Thank you for sharing it

good luck let me know the results

 

[Sadist]

this is a nose enlargement thread tho, also made with gpt

 

[shneekmax]

Mirin this nice guide BOTB

 

[Ban3r]

Mirin this nice guide BOTB

thanks bhai

 

[mhmd12322]

Bump

 

[JohnDoe]

Troll thread

 

[pahadi mogger]

After years of experimenting with facial hypertrophy and dermal modulation, researchers (and certain underground aesthetics pioneers) have discovered a groundbreaking synergy between topical minoxidil and Volufiline™ when applied to nasal tissue.

While traditionally used for hair growth (minoxidil) and fat volumization (Volufiline), when combined in precise ratios and applied under specific conditions, the compounds induce a compensatory atrophic remodeling response in the nasal matrix, resulting in measurable nose size reduction and improved nasofacial harmony.

This process is known as MinoxiVolufiline Induced Nasal Remodeling (MNRP).

So let’s get into why;
The MNRP synergy acts via a cascade of pseudo-biochemical interactions that target the naso-cartilaginous feedback axis (NCFA), a system rarely studied in conventional dermatology.

1. Minoxidil - Nasal β3-Adrenoceptor Upregulation
Minoxidil binds to the β3-NAR (Beta-3 Naso-Adreno Receptor), a receptor subtype expressed in perichondrial fibroblasts. This stimulates cyclic AMP elevation and transient cartilaginous edema, triggering controlled tissue stress adaptation.

2. Volufiline - Sphingo-Collagenic Receptor Modulation (SCR-2)
Volufiline’s active ingredient (sarsasapogenin) acts on the SCR-2 receptor, a newly identified sphingolipid-sensitive collagen receptor. In nasal tissue, this paradoxically causes adipocyte dedifferentiation rather than volumization, resulting in localized dermal thinning and cartilage tightening.

3. Cross-Receptor Interference
When both compounds are co-applied, β3-NAR and SCR-2 activation lead to cross-talk at the naso-integrin complex (NIC-α5β7), which upregulates collagen type XIV synthesis inhibitors (notably Prolyl-Hydroxase Negative Isoform 3, PHNI3). This biochemical chaos culminates in micro-cartilage contraction, perceived visually as a smaller, sharper, more refined nose

Application Protocol

Materials:

• 5% Minoxidil solution
• Volufiline cream or serum (10% concentration preferred)
• Microneedling device (0.25 mm)
• Alcohol pads
• Cold compress

Procedure (Nightly):

1. Cleanse the nasal area with alcohol pad.
2. Microneedle the nasal bridge and tip lightly (0.25 mm depth).
3. Apply 1 drop of Minoxidil evenly across the nose.
4. Wait 10 minutes for absorption.
5. Apply a pea-sized amount of Volufiline over the same area.
6. Optional: Apply cold compress for 2–3 minutes to enhance receptor stabilization.

Cycle:
6 days on, 1 day off, for 8–12 weeks.

The MinoxiVolufiline Nasal Remodeling Protocol is a frontier-tier bioaesthetic enhancement stack that leverages pseudo-endocrine signaling for non-surgical nasal refinement. While still in the experimental phase, anecdotal results suggest potential to outperform traditional rhinoplasty in subtlety and recovery time.

This is a fascinating write-up, and I appreciate the thoroughness of your comments on the theory.

I must say the biochemistry you refer to is new to me. Can you help me better understand a couple of things?

Specifically, I am intrigued by the "Naso-cartilaginous feedback axis (NCFA)" and "SCR-2 receptor." These are mechanisms I have never encountered in dermatology or endocrinology literature. Could you refer me to the research or papers from which you derived these conclusions? I would really like to read the primary sources.

 

[Ban3r]

Troll thread

haters gonna hate

 

[Ban3r]

This is a fascinating write-up, and I appreciate the thoroughness of your comments on the theory.

I must say the biochemistry you refer to is new to me. Can you help me better understand a couple of things?

Specifically, I am intrigued by the "Naso-cartilaginous feedback axis (NCFA)" and "SCR-2 receptor." These are mechanisms I have never encountered in dermatology or endocrinology literature. Could you refer me to the research or papers from which you derived these conclusions? I would really like to read the primary sources.

yeah sure as soon as im home

 

[JohnDoe]

haters gonna hate

September join date, chatgpt slop thread intended to fuck up underaged kids who think this will work, shut up retard

 

[Ban3r]

September join date, chatgpt slop thread intended to fuck up underaged kids who think this will work, shut up retard

who the fuck are you nigga

 

[JohnDoe]

who the fuck are you nigga

who are you? chatgpt threads aren't allowed dumb ass nigga

 

[Ban3r]

who are you? chatgpt threads aren't allowed dumb ass nigga

crying wont unrape you lil nigga

 

[pahadi mogger]

crying wont unrape you lil nigga

Brother can you get home faster so I can read the primary source?

 

[JohnDoe]

This is a fascinating write-up, and I appreciate the thoroughness of your comments on the theory.

I must say the biochemistry you refer to is new to me. Can you help me better understand a couple of things?

Specifically, I am intrigued by the "Naso-cartilaginous feedback axis (NCFA)" and "SCR-2 receptor." These are mechanisms I have never encountered in dermatology or endocrinology literature. Could you refer me to the research or papers from which you derived these conclusions? I would really like to read the primary sources.

nice chatgpt reply greycel, two greycels being retarded, what a great thread

 

[Ban3r]

Brother can you get home faster so I can read the primary source?

yes i will try be faster

 

[Ban3r]

nice chatgpt reply greycel, two greycels being retarded, what a great thread

cry about it nigger

 

[savage21]

After years of experimenting with facial hypertrophy and dermal modulation, researchers (and certain underground aesthetics pioneers) have discovered a groundbreaking synergy between topical minoxidil and Volufiline™ when applied to nasal tissue.

While traditionally used for hair growth (minoxidil) and fat volumization (Volufiline), when combined in precise ratios and applied under specific conditions, the compounds induce a compensatory atrophic remodeling response in the nasal matrix, resulting in measurable nose size reduction and improved nasofacial harmony.

This process is known as MinoxiVolufiline Induced Nasal Remodeling (MNRP).

So let’s get into why;
The MNRP synergy acts via a cascade of pseudo-biochemical interactions that target the naso-cartilaginous feedback axis (NCFA), a system rarely studied in conventional dermatology.

1. Minoxidil - Nasal β3-Adrenoceptor Upregulation
Minoxidil binds to the β3-NAR (Beta-3 Naso-Adreno Receptor), a receptor subtype expressed in perichondrial fibroblasts. This stimulates cyclic AMP elevation and transient cartilaginous edema, triggering controlled tissue stress adaptation.

2. Volufiline - Sphingo-Collagenic Receptor Modulation (SCR-2)
Volufiline’s active ingredient (sarsasapogenin) acts on the SCR-2 receptor, a newly identified sphingolipid-sensitive collagen receptor. In nasal tissue, this paradoxically causes adipocyte dedifferentiation rather than volumization, resulting in localized dermal thinning and cartilage tightening.

3. Cross-Receptor Interference
When both compounds are co-applied, β3-NAR and SCR-2 activation lead to cross-talk at the naso-integrin complex (NIC-α5β7), which upregulates collagen type XIV synthesis inhibitors (notably Prolyl-Hydroxase Negative Isoform 3, PHNI3). This biochemical chaos culminates in micro-cartilage contraction, perceived visually as a smaller, sharper, more refined nose

Application Protocol

Materials:

• 5% Minoxidil solution
• Volufiline cream or serum (10% concentration preferred)
• Microneedling device (0.25 mm)
• Alcohol pads
• Cold compress

Procedure (Nightly):

1. Cleanse the nasal area with alcohol pad.
2. Microneedle the nasal bridge and tip lightly (0.25 mm depth).
3. Apply 1 drop of Minoxidil evenly across the nose.
4. Wait 10 minutes for absorption.
5. Apply a pea-sized amount of Volufiline over the same area.
6. Optional: Apply cold compress for 2–3 minutes to enhance receptor stabilization.

Cycle:
6 days on, 1 day off, for 8–12 weeks.

The MinoxiVolufiline Nasal Remodeling Protocol is a frontier-tier bioaesthetic enhancement stack that leverages pseudo-endocrine signaling for non-surgical nasal refinement. While still in the experimental phase, anecdotal results suggest potential to outperform traditional rhinoplasty in subtlety and recovery time.

Jfl at niggas who believe this

 

[Ban3r]

Jfl at niggas who believe this

they will ascend while u stay in ltn hell mate

 

[BaranPSL]

View attachment 4207514View attachment 4207515

I need to opposite jfl

 

[savage21]

they will ascend while u stay in ltn hell mate

Alr troll ass nigga

 

[Ban3r]

Alr troll ass nigga

its fine bro if u dont want to ascend dont stop others from doing so…

 

[pahadi mogger]

its fine bro if u dont want to ascend dont stop others from doing so…

Hey dude, been thinking about your protocol? Really cool concepts with stacking the compounds. I made a couple of tweaks to the biological mechanism a little more efficacious, added tretinoin for results shown in collagen remodeling and a little bromelain in hopes to stimulate cartilage plasticity. Basically enhances the mechanism you have in place but more directly to soft tissue and cartilage structures. Thoughts?

 

[Ban3r]

Hey dude, been thinking about your protocol? Really cool concepts with stacking the compounds. I made a couple of tweaks to the biological mechanism a little more efficacious, added tretinoin for results shown in collagen remodeling and a little bromelain in hopes to stimulate cartilage plasticity. Basically enhances the mechanism you have in place but more directly to soft tissue and cartilage structures. Thoughts?

avoid combining tretinoin, everything else seems good

 

[pahadi mogger]

avoid combining tretinoin, everything else seems good

Absolutely fair assessment, man. You're correct, simplicity and no conflicts with the ingredients is the way to go. Your original protocol using Minoxidil and Volufiline is great for a base.

Why not just think about the two compound ingredients and optimise them? Get the dosing and timing right and maybe even microneedling depth, getting the synergy working well without getting silly complicated.

Your call. It is your protocol ,just trying to help

 

[Ban3r]

Absolutely fair assessment, man. You're correct, simplicity and no conflicts with the ingredients is the way to go. Your original protocol using Minoxidil and Volufiline is great for a base.

Why not just think about the two compound ingredients and optimise them? Get the dosing and timing right and maybe even microneedling depth, getting the synergy working well without getting silly complicated.

Your call. It is your protocol ,just trying to help

could experiment more on it for sure i will see what i can do

 

[Ban3r]

bump

 

[gigacumster3000]

wtf fr? how does it work tho?? never heard of volumetric remodeling or whatever you said but sounds wild lemme read thru the thread jfl

 

[gigacumster3000]

sounds like a lot of cope to me tbh

 

[weepmeep]

On the first day I tried it and my nose swelled a little, but I felt like the blood vessels had expanded a little. then I noticed a strange change, my nose started to get covered with small curly hairs, I got scared and had to stop the experiments

 

[Ban3r]

On the first day I tried it and my nose swelled a little, but I felt like the blood vessels had expanded a little. then I noticed a strange change, my nose started to get covered with small curly hairs, I got scared and had to stop the experiments

you are doing something wrong

 

[Ban3r]

bump

 

[slaters]

Why would I want hair on my nose

 

[Ban3r]

Why would I want hair on my nose

it wont give you hair on nose

 

[shneekmax]

w thread

 

[Jesko]

After years of experimenting with facial hypertrophy and dermal modulation, researchers (and certain underground aesthetics pioneers) have discovered a groundbreaking synergy between topical minoxidil and Volufiline™ when applied to nasal tissue.

While traditionally used for hair growth (minoxidil) and fat volumization (Volufiline), when combined in precise ratios and applied under specific conditions, the compounds induce a compensatory atrophic remodeling response in the nasal matrix, resulting in measurable nose size reduction and improved nasofacial harmony.

This process is known as MinoxiVolufiline Induced Nasal Remodeling (MNRP).

So let’s get into why;
The MNRP synergy acts via a cascade of pseudo-biochemical interactions that target the naso-cartilaginous feedback axis (NCFA), a system rarely studied in conventional dermatology.

1. Minoxidil - Nasal β3-Adrenoceptor Upregulation
Minoxidil binds to the β3-NAR (Beta-3 Naso-Adreno Receptor), a receptor subtype expressed in perichondrial fibroblasts. This stimulates cyclic AMP elevation and transient cartilaginous edema, triggering controlled tissue stress adaptation.

2. Volufiline - Sphingo-Collagenic Receptor Modulation (SCR-2)
Volufiline’s active ingredient (sarsasapogenin) acts on the SCR-2 receptor, a newly identified sphingolipid-sensitive collagen receptor. In nasal tissue, this paradoxically causes adipocyte dedifferentiation rather than volumization, resulting in localized dermal thinning and cartilage tightening.

3. Cross-Receptor Interference
When both compounds are co-applied, β3-NAR and SCR-2 activation lead to cross-talk at the naso-integrin complex (NIC-α5β7), which upregulates collagen type XIV synthesis inhibitors (notably Prolyl-Hydroxase Negative Isoform 3, PHNI3). This biochemical chaos culminates in micro-cartilage contraction, perceived visually as a smaller, sharper, more refined nose

Application Protocol

Materials:

• 5% Minoxidil solution
• Volufiline cream or serum (10% concentration preferred)
• Microneedling device (0.25 mm)
• Alcohol pads
• Cold compress

Procedure (Nightly):

1. Cleanse the nasal area with alcohol pad.
2. Microneedle the nasal bridge and tip lightly (0.25 mm depth).
3. Apply 1 drop of Minoxidil evenly across the nose.
4. Wait 10 minutes for absorption.
5. Apply a pea-sized amount of Volufiline over the same area.
6. Optional: Apply cold compress for 2–3 minutes to enhance receptor stabilization.

Cycle:
6 days on, 1 day off, for 8–12 weeks.

The MinoxiVolufiline Nasal Remodeling Protocol is a frontier-tier bioaesthetic enhancement stack that leverages pseudo-endocrine signaling for non-surgical nasal refinement. While still in the experimental phase, anecdotal results suggest potential to outperform traditional rhinoplasty in subtlety and recovery time.

Might give this a go, mirin bro