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Kraken
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sarms increase facial masculinitythese drugs all have vastly different purposes. cardarine is for cardio performance not muscle mass. depends on your goals but wouldnt touch rad or lgd yet
sarms don't suppress youall androgens do, whats your point. the vast majority (stuff like clomid and proviron being exceptions) will also suppress you
have fun buddysarms don't suppress you
brutal are you shoreDon’t touch any but maybe cardarine. Basically you will fuck your endocrine system if you take sarms, and mk677 is the fucking worst HGH secretagogue and it doesn’t even increase igf-1 (the shit you actually need).
how much do you takeI grew an inch and a half with MK 677 in 3 weeks. Not cope if your growth plates are open and eating 3000 calories a day.
Who told you m677 doesn’t increase igf-1?Don’t touch any but maybe cardarine. Basically you will fuck your endocrine system if you take sarms, and mk677 is the fucking worst HGH secretagogue and it doesn’t even increase igf-1 (the shit you actually need).
Studies cuntWho told you m677 doesn’t increase igf-1?
What?Studies cunt
Are you trolling? This is major lifefuel if true.I grew an inch and a half with MK 677 in 3 weeks. Not cope if your growth plates are open and eating 3000 calories a day.
It’s cope.Are you trolling? This is major lifefuel if true.
what studies?Studies cunt
Yeah if you actually understand data those increases are not significant. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/what studies?
Growth hormone secretagogue MK-677
Background: In animals, insulin-like growth factor-1 (IGF-1) increases clearance of β-amyloid, a pathologic hallmark of Alzheimer disease (AD), from the CNS. Serum IGF-1 level decreases with age, and shows a further decrease in AD. We examined whether the growth hormone secretagogue MK-677...n.neurology.org
"Administration of MK-677 25 mg resulted in a 60.1% increase in serum IGF-1 levels at 6 weeks and a 72.9% increase at 12 months."
Effect of alendronate and MK-677 (a growth hormone secretagogue), individually and in combination, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women - PubMed
GH increases bone turnover and stimulates osteoblast activity. We hypothesized that administration of MK-677, an orally active GH secretagogue, together with alendronate, a potent inhibitor of bone resorption, would maintain a higher bone formation rate relative to that seen with alendronate...pubmed.ncbi.nlm.nih.gov
"The primary results, except for BMD, are provided for month 12. MK-677, with or without alendronate, increased insulin-like growth factor I levels from baseline (39% and 45%; P < 0.05 vs. placebo)"
Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males - PubMed
The effect of 2 months of treatment with the oral growth hormone (GH) secretagogue MK-677 on markers of bone metabolism was determined in healthy obese male subjects. This was a randomized, double-blind, parallel, placebo-controlled study. Twenty-four healthy obese males, 19-49 years of age...pubmed.ncbi.nlm.nih.gov
"Large increases in serum levels of IGF-1 and IGFBP-5 and a transient increase in serum IGFBP-4 were found."
none of these I suppose
Lmao in rats maybeYeah if you actually understand data those increases are not significant. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240568/
The data is misinterpreted, the percentage increase isn’t high enough to have a large effect on height growth.Lmao in rats maybe
im providing human studies
Effect of alendronate and MK-677 (a growth hormone secretagogue), individually and in combination, on markers of bone turnover and bone mineral density in postmenopausal osteoporotic women - PubMed
GH increases bone turnover and stimulates osteoblast activity. We hypothesized that administration of MK-677, an orally active GH secretagogue, together with alendronate, a potent inhibitor of bone resorption, would maintain a higher bone formation rate relative to that seen with alendronate...pubmed.ncbi.nlm.nih.gov
"MK-677, with or without alendronate, increased insulin-like growth factor I levels from baseline (39% and 45%; P < 0.05 vs. placebo)"
please tell me how they're misinterpreting their data, especially testing the significance jfl
Height growth yes, its bs for that but you were saying it doesn’t increase igf-1 when it clearly does.The data is misinterpreted, the percentage increase isn’t high enough to have a large effect on height growth.
I never said they where misinterpreting, you are. By all means take it for osteoporosis but I’m pretty sure you where recommending it for height growth as this is what the thread is aboutHeight growth yes, its bs for that but you were saying it doesn’t increase igf-1 when it clearly does.
theyre not misinterpreting anything, they were looking at it as a treatment for osteoporosis, nothing to do with height growth idk why youre bringing that up.
they tested to see if the increase in igf-1 levels between the mk-677 standalone group and the placebo were significant at a 5% level and they were, theres no room for misinterpreting there, it increases igf.
I'm literally not interpreting anything, just repeating what the researchers are saying in different terms.I never said they where misinterpreting, you are. By all means take it for osteoporosis but I’m pretty sure you where recommending it for height growth as this is what the thread is about
Mk677 does nothing but add water and maybe slightly aid in sleep. Might give u some nice tits too since it increases prolactin almost as much as igf-1. https://asbmr.onlinelibrary.wiley.com/doi/10.1359/jbmr.1999.14.7.1182 plus this increase is more likely to Effect you than the slight igf-1 boost. Mk677 is massive cope and might only be useful when used with cjc-1295 DAC as it will make mk have stronger pulsesI'm literally not interpreting anything, just repeating what the researchers are saying in different terms.
I never recommended mk667 for height growth, this thread is not about height growth, OP seems to want to take sarms for facial masculinity and thinks mk677 is a sarm.
missed you chadMk677 does nothing but add water and maybe slightly aid in sleep. Might give u some nice tits too since it increases prolactin almost as much as igf-1. https://asbmr.onlinelibrary.wiley.com/doi/10.1359/jbmr.1999.14.7.1182 plus this increase is more likely to Effect you than the slight igf-1 boost. Mk677 is massive cope and might only be useful when used with cjc-1295 DAC as it will make mk have stronger pulses
It’s been awhile brother, to me capromorelin is the better oral hgh secretagogue.missed you chad