Lars
Softmaxx 👑
- Joined
- Oct 10, 2019
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Wait what? Nicotine that addicting shit to keep people smoking those cancer sticks called cigs?
Yes Nicotine.
Nicotine alone has alot benefits despide being addictive asfuck so dont recommend it if you aren't using nicotine but all the kids these days are addicted to JUULS so here are reasons to cope with nicotine addiction and say you use it for the benefiting effects instead of your crippeling addiction! (i am also addicted rn to throwable vapes lol)
would never smoke cigs because they stain teeth and cause cancer way faster only would say recommend Nicotine in the form of a Vape, gum , or Patch
Nicotine boosts DHT by inhibiting the enzyme, 3α-HSD, which is the enzyme that breaks DHT down into 3α-androstanediol, a weaker androgen.
ALL CREDDITS TO HANS AMATO FROM MEN-ELITE I EXPIRE HIS WORK - Lars
why DHT?
men-elite.com
DHT, the apex androgen for all men.
Testosterone is only thought to be a precursor hormone in the body for the synthesis of DHT, which is the most potent alpha hormone. It’s like cholesterol that’s the precursor to pregnenolone and testosterone.
Many of the beneficial effect of testosterone is actually through DHT, and blocking the conversion of testosterone to DHT eliminates those benefits.
Testosterone is converted to DHT via the 5-alpha reductase (5-AR) enzyme in the body. Although testosterone is a major contributor to circulating DHT, DHT can also be created from other precursors, such as DHEA, androstenedione, androsterone, 17-hydroxypregnenolone and 17-hydroxyprogesterone.
In the blood, DHT is also bound to SHBG (5 times high affinity and longer binding halflife (43 sec) than T (12 sec)) and more weakly to albumin. In general, protein-bound DHT is inactive except in some reproductive tissues in which megalin, an endocytic receptor, acts as a pathway for cellular uptake of DHT when bound to SHBG.
And finally, DHT can’t be aromatized to estrogen and actually inhibits the aromatase (R) and blocks the estrogen receptors (R).
Ok, enough geeking out.
Let’s discuss why you even want high DHT in the first place.
Like I mentioned, the benefits of high testosterone is mostly due to the conversion of DHT.
So having high DHT will make you feel:
It truly is a hormone we want to maximize alongside testosterone, dopamine and thyroid. Keep in mind that the body is complicated and that all hormones need to work together for all the benefits.
DHT is also the most important hormone for puberty:
Effect of Dihydrotestosterone
Dihydrotestosterone is a hormone that stimulates the development of male characteristics (an androgen). It is made through conversion of the more commonly known androgen, Testosterone. However you can also take DHT
Growth of body hair, including underarm, abdominal, chest hair and pubic hair. Loss of scalp hair due to androgenic alopecia can also occur.
Greater mass of thigh muscles in front of the femur, rather than behind it as is typical in mature females
Growth of facial hair
Enlargement of larynx (Adam’s apple) and deepening of voice[3]
Increased stature; adult males are taller than adult females, on average
Heavier skull and bone structure
Increased muscle mass and strength
Larger hands, feet and nose than women, prepubescent boys, and girls
Larger bodies
Square face
Small waist, but wider than females
Broadening of shoulders and chest; shoulders wider than hips[4]
Increased secretions of oil and sweat glands, often causing acne and body odor[3]
Coarsening or rigidity of skin texture due to less subcutaneous fat
Higher waist-to-hip ratio than prepubescent or adult females or prepubescent males, on average
Lower bodyfat percentage than prepubescent or adult females or prepubescent males, on average
Enlargement (growth) of the penis (during puberty)
Nicotine Also acts as an potent Aromasin
men-elite.com
Estrogen, the female hormone, or the modern man hormone?
Men always had estrogen more on the low side of the normal ranges, but nowadays, estrogen is rapidly on the rise and men do experience high estrogen symptoms.
It’s not only due to the rapid conversion of testosterone to estrogen, but also the significant amounts of estrogenic compounds that are found in nature, such as phytoestrogens ( natural estrogens certain foods, such as soy and flax), mold, herbicides, food colorants, especially red colourant, birth control in the water, plastics, and so much more.
But apart from the estrogens in nature, we also convert a lot more testosterone into estrogen than we used to a few decades ago. This is due to a couple of reasons that we’ll discuss below.
Blocking the aromatase is crucial for decreasing excess estrogen, whether you have high testosterone or not. Lower activity of aromatase leaves more testosterone to bind with androgen receptors as well as to be converted to DHT via 5-AR (5 alpha reductase), the most potent androgen.
There is increasing controversy whether estrogen is actually very desirable for men and that men on testosterone replacement therapy (TRT) need high estrogen, which is “protective”. What most estro-philes that promote TRT don’t tell you is that TRT lowers LH. LH signals the testes to produce what? Testosterone? Now you’re jumping the gun. First and foremost, pregnenolone is created, then progesterone and DHEA and then testosterone. What if I told you pregnenolone, progesterone and DHEA is actually the primary cardioprotectors and not estrogen? But that is for another article.
High Estrogen symptoms include:
Keep in mind, estrogen and prolactin go hand in hand and some of these symptoms might be the same. More on lowering prolactin here. Estrogen also increases serotonin and inhibits 5-alpha reductase.
Estrogen is classified as a stress hormone. It increases in times of stress, both physical and emotional. Exercise, on the other hand, is a healthy stressor, and actually helps rid the body of estrogen.
Yes Nicotine.
Nicotine alone has alot benefits despide being addictive asfuck so dont recommend it if you aren't using nicotine but all the kids these days are addicted to JUULS so here are reasons to cope with nicotine addiction and say you use it for the benefiting effects instead of your crippeling addiction! (i am also addicted rn to throwable vapes lol)
would never smoke cigs because they stain teeth and cause cancer way faster only would say recommend Nicotine in the form of a Vape, gum , or Patch
Nicotine boosts DHT by inhibiting the enzyme, 3α-HSD, which is the enzyme that breaks DHT down into 3α-androstanediol, a weaker androgen.
ALL CREDDITS TO HANS AMATO FROM MEN-ELITE I EXPIRE HIS WORK - Lars
why DHT?
43 best ways to increase DHT (2023 update) » TESTONATION
I'm going to show you how to increase DHT (our strongest androgen) with many dietary, lifestyle and supplemental tricks.
men-elite.com
Testosterone is only thought to be a precursor hormone in the body for the synthesis of DHT, which is the most potent alpha hormone. It’s like cholesterol that’s the precursor to pregnenolone and testosterone.
Many of the beneficial effect of testosterone is actually through DHT, and blocking the conversion of testosterone to DHT eliminates those benefits.
Testosterone is converted to DHT via the 5-alpha reductase (5-AR) enzyme in the body. Although testosterone is a major contributor to circulating DHT, DHT can also be created from other precursors, such as DHEA, androstenedione, androsterone, 17-hydroxypregnenolone and 17-hydroxyprogesterone.
A few really cool facts about DHT why it’s superior to testosterone
DHT is 2.5-10 times more potent than testosterone and here’s why:- DHT has 4 times higher affinity to AR (androgen receptors) than testosterone
- Binding of DHT to the AR transforms the AR to its DNA-binding state
- DHT upregulates AR synthesis and reduces AR turnover
- The dissociation rate of testosterone from receptors is 3-5 fold faster than DHT (meaning DHT exerts a much more powerful effect on AR than testosterone)
In the blood, DHT is also bound to SHBG (5 times high affinity and longer binding halflife (43 sec) than T (12 sec)) and more weakly to albumin. In general, protein-bound DHT is inactive except in some reproductive tissues in which megalin, an endocytic receptor, acts as a pathway for cellular uptake of DHT when bound to SHBG.
And finally, DHT can’t be aromatized to estrogen and actually inhibits the aromatase (R) and blocks the estrogen receptors (R).
Ok, enough geeking out.
Let’s discuss why you even want high DHT in the first place.
Like I mentioned, the benefits of high testosterone is mostly due to the conversion of DHT.
So having high DHT will make you feel:
- Calm and collected
- Confident & non-intimidated by others
- Fearless, but not reckless
- Protective of those you love
- Assertive
- Energetic
- Motivated
- Stress resilient
- Mentally quick and sharp
It truly is a hormone we want to maximize alongside testosterone, dopamine and thyroid. Keep in mind that the body is complicated and that all hormones need to work together for all the benefits.
DHT is also the most important hormone for puberty:
https://forum.****************/threads/dihydrotestosterone-puberty-guide.2332/
Effect of Dihydrotestosterone
Dihydrotestosterone is a hormone that stimulates the development of male characteristics (an androgen). It is made through conversion of the more commonly known androgen, Testosterone. However you can also take DHT
Growth of body hair, including underarm, abdominal, chest hair and pubic hair. Loss of scalp hair due to androgenic alopecia can also occur.
Greater mass of thigh muscles in front of the femur, rather than behind it as is typical in mature females
Growth of facial hair
Enlargement of larynx (Adam’s apple) and deepening of voice[3]
Increased stature; adult males are taller than adult females, on average
Heavier skull and bone structure
Increased muscle mass and strength
Larger hands, feet and nose than women, prepubescent boys, and girls
Larger bodies
Square face
Small waist, but wider than females
Broadening of shoulders and chest; shoulders wider than hips[4]
Increased secretions of oil and sweat glands, often causing acne and body odor[3]
Coarsening or rigidity of skin texture due to less subcutaneous fat
Higher waist-to-hip ratio than prepubescent or adult females or prepubescent males, on average
Lower bodyfat percentage than prepubescent or adult females or prepubescent males, on average
Enlargement (growth) of the penis (during puberty)
Nicotine Also acts as an potent Aromasin
Inhibit Aromatase: 31 Potent Supplements » MENELITE
Estrogen, the female hormone, or the modern man hormone? Men always had estrogen more on the low side of the normal ranges, but nowadays, estrogen is rapidly on the rise … Continue reading Inhibit Aromatase: 31 Potent Supplements
men-elite.com
Estrogen, the female hormone, or the modern man hormone?
Men always had estrogen more on the low side of the normal ranges, but nowadays, estrogen is rapidly on the rise and men do experience high estrogen symptoms.
It’s not only due to the rapid conversion of testosterone to estrogen, but also the significant amounts of estrogenic compounds that are found in nature, such as phytoestrogens ( natural estrogens certain foods, such as soy and flax), mold, herbicides, food colorants, especially red colourant, birth control in the water, plastics, and so much more.
But apart from the estrogens in nature, we also convert a lot more testosterone into estrogen than we used to a few decades ago. This is due to a couple of reasons that we’ll discuss below.
Blocking the aromatase is crucial for decreasing excess estrogen, whether you have high testosterone or not. Lower activity of aromatase leaves more testosterone to bind with androgen receptors as well as to be converted to DHT via 5-AR (5 alpha reductase), the most potent androgen.
There is increasing controversy whether estrogen is actually very desirable for men and that men on testosterone replacement therapy (TRT) need high estrogen, which is “protective”. What most estro-philes that promote TRT don’t tell you is that TRT lowers LH. LH signals the testes to produce what? Testosterone? Now you’re jumping the gun. First and foremost, pregnenolone is created, then progesterone and DHEA and then testosterone. What if I told you pregnenolone, progesterone and DHEA is actually the primary cardioprotectors and not estrogen? But that is for another article.
High Estrogen symptoms include:
- Pelvic pain
- Night wakings and sweats (can’t sleep through the night)
- Hot flashes
- Edema, puffiness, water retention
- Increased risk of a migraine
- Low body temp (can also be low thyroid)
- Brain fog
- Frequent urination during the night (small bladder feeling)
- Struggle to build muscle
- Gynecomastia
- Fatigue and depression
- Poor memory
- Mood swings
- Low libido
Keep in mind, estrogen and prolactin go hand in hand and some of these symptoms might be the same. More on lowering prolactin here. Estrogen also increases serotonin and inhibits 5-alpha reductase.
Estrogen is classified as a stress hormone. It increases in times of stress, both physical and emotional. Exercise, on the other hand, is a healthy stressor, and actually helps rid the body of estrogen.
Estrogen:
- potently lowers steroidogenesis, much more potent than DHT
- inhibits DHEA production by inhibiting 17 alpha-hydroxylase and (or) C17-C20 lyase activity (R)
- can promote thyroid dysfunction as well as autoimmunity by enhancing NADPH oxidase and excess free radical production (R)
- promotes excess lipolysis that leads to elevated free fatty acids and insulin resistance
- increases IL-17 (R), an inflammatory cytokine, which is potently correlated with anhedonia and autoimmune disease.
- increase the risk of stroke and thrombosis (R), by promoting excess blood clotting
- promotes anxiety
- increases serotonin production and potentiates the effect of serotonin
- creates gyno
- increases total and free cortisol. This effect is blunted by progesterone (R, R)
- elevates prolactin
- promotes aldosterone, which causes water retention (R)
- increases adipogenesis (creation of new fat cells) (R)
- increases thyroxine-binding globulin, which decreases free thyroid hormones (R)
- increases fat uptake in the adipose tissue by increasing PPARγ and fatty acid-binding protein (R).
- increases brain excitation and can contribute to seizures. Aromatase inhibitors are useful against epilepsy (R)
- Reduces bile flow from the liver to the gallbladder, which can lead to intrahepatic cholestasis (R). This can lead to the skin and whites of the eyes looking yellow, the skin itches, urine is dark, and stools may become light-coloured and smell foul.
- increases lactate production from glucose which is a very ineffective method of producing energy. Lactate itself also possesses many negative effects (R).
- promotes migraines (R)
- causes testicular degeneration (R)
- decreases FGF21, which result in lower thermogenesis and energy expenditure (R)
