bonelessvirgin
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The following text comes from ChatGPT but its still very interesting:
When someone uses a high dose of androgens — for example, 500 mg of testosterone per week — both testosterone and estrogen rise because a portion of that testosterone is converted to estradiol via the aromatase enzyme. So, the ratio between androgens and estrogens often stays roughly stable (around 20:1 to 30:1) unless an aromatase inhibitor is used.
Now, to your main question:
Is high estrogen still beneficial as long as it’s in the right ratio to androgens?
For bone health, yes. Estrogen is absolutely essential for maintaining bone density — in men as well as women. When both testosterone and estrogen are elevated, bone density usually increases beyond normal physiological levels, because:
When someone uses a high dose of androgens — for example, 500 mg of testosterone per week — both testosterone and estrogen rise because a portion of that testosterone is converted to estradiol via the aromatase enzyme. So, the ratio between androgens and estrogens often stays roughly stable (around 20:1 to 30:1) unless an aromatase inhibitor is used.
Now, to your main question:
Is high estrogen still beneficial as long as it’s in the right ratio to androgens?
For bone health, yes. Estrogen is absolutely essential for maintaining bone density — in men as well as women. When both testosterone and estrogen are elevated, bone density usually increases beyond normal physiological levels, because:
- Testosterone directly stimulates osteoblasts (bone-building cells),
- Estrogen inhibits osteoclasts (bone-resorbing cells) and prolongs osteoblast lifespan.