Zindaclin: The Most Underrated Acne Topical on the Market

[copercel123]

A short thread just to let yall know what of a masterpiece is it.
I gatekeeped it to see if it actually have some benefits and holy fuck, my skin is so much better- less acne, less breakouts, my skin became healthier, less redness, pustules shrank etc etc.

Nobody mentions Zindaclin, but they should.

Basically
It’s a topical clindamycin gel (1%) that quietly obliterates inflammatory acne without wrecking your skin barrier. No hype, no memes, just results (at least in my case)

I used it when tret nuked my skin. Within 2 weeks, redness calmed down, pustules shrank, skin tone normalized. Almost no side effects.

Zindaclin-
It’s good for

Red, swollen acne.
Jawline + cheek clusters.
Sensitive/reactive skin.
Barrier recovery while still treating acne.

Some tips to maximize its effectiveness-

Pair with BPO to prevent resistance.

Layer under moisturizer to reduce dryness.

Once inflammation is controlled, introduce retinoids (Taz) for long-term skin turnover.

ZINDACLIN 1% GEL | Drugs.com

Patient information for ZINDACLIN 1% GEL Including dosage instructions and possible side effects.

www.drugs.com

Good luck.

Tags
@kazama
@jeff1234
@Evgeniy291

 

[piec]

the most underrated is clearly accutane since there are still people who cope with this garbage

 

[Bryce]

If I had bad skin I'd definitely try this out

 

[chadisbeingmade]

Most underrated is unironically Dutasteride.

 

[kazama]

Zindaclin-
It’s good for

Red, swollen acne.
Jawline + cheek clusters.
Sensitive/reactive skin.
Barrier recovery while still treating acne

I fit into this, but apparently it is not available in my country

 

[DR. NICKGA]

Any studies?

 

[copercel123]

the most underrated is clearly accutane since there are still people who cope with this garbage

Accutane and underrated in the same sentence holy fuck. Accutane is the one of the most used acne medication in the world world right now

 

[copercel123]

Most underrated is unironically Dutasteride.

For acne?

 

[chadisbeingmade]

For acne?

Androgens = up regulation of sebaceous glands = more oil and sebum production = more acne.

 

[mogandpillage]

I used it when tret nuked my skin

why did it nuke ur skin? Maybe you should’ve carried on to see results

 

[copercel123]

Any studies?

https://onlinelibrary.wiley.com/doi/abs/10.1111/dth.12576?utm

 

[copercel123]

why did it nuke ur skin? Maybe you should’ve carried on to see results

No. Tret is shit, just take Tazerotene

 

[mogandpillage]

No. Tret is shit, just take Tazerotene

I’m already on tret but why do you say it’s shit?

 

[copercel123]

I’m already on tret but why do you say it’s shit?

Just isn’t potent enough to acne, Tazerotene is.

 

[piec]

Accutane is the one of the most used acne medication in the world world right now

apparently not enough

 

[Jonas2k7]

Androgens = up regulation of sebaceous glands = more oil and sebum production = more acne.

Zindaclin is a dogshit compound, like you said just block 5AR.

Add isotretinoin to that and you're set for life.

It's an antibiotic btw.

"the excessive use of clindamycin topicals in treating acne is thought to contribute to the greater incidence of 23S rRNA mutations in C. acnes strains"

Just let your genes mutate theory. You also build resistance to the compound.

Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease - PMC

Clindamycin is a highly effective antibiotic of the lincosamide class. It has been widely used for decades to treat a range of skin and soft tissue infections in dermatology and medicine. Clindamycin is commonly prescribed for acne vulgaris, with ...

pmc.ncbi.nlm.nih.gov

 

[mogandpillage]

Just isn’t potent enough to acne, Tazerotene is.

I’ll try both

 

[copercel123]

Zindaclin is a dogshit compound, like you said just block 5AR.

Add isotretinoin to that and you're set for life.

It's an antibiotic btw.

"the excessive use of clindamycin topicals in treating acne is thought to contribute to the greater incidence of 23S rRNA mutations in C. acnes strains"

Just let your genes mutate theory. You also build resistance to the compound.

Scientific Rationale and Clinical Basis for Clindamycin Use in the Treatment of Dermatologic Disease - PMC

Clindamycin is a highly effective antibiotic of the lincosamide class. It has been widely used for decades to treat a range of skin and soft tissue infections in dermatology and medicine. Clindamycin is commonly prescribed for acne vulgaris, with ...

pmc.ncbi.nlm.nih.gov

Yes, “excessive use” that’s the good part, when in a lot of cases you don’t need to use it excessively, you can use for 3 weeks or even to 12 weeks and in a lot of cases it will help reduce acne in the long term. So well yeah that’s True, Zindaclin is an antibiotic, so resistance is a real concern, especially if used long-term or without something like benzoyl peroxide. That’s why most derms recommend limiting clindamycin monotherapy duration and combining it with BPO to reduce resistance risk.

But it’s still a solid anti-inflammatory option for mild to moderate acne, especially if you want to avoid the dryness and irritation of harsher treatments

 

[Evgeniy291]

dont be acne prone and have no breakouts at 3000ng/dl test theory

 

[AverageCurryEnjoyer]

low dose accutane mogs. Need to try it out soon

 

[Evgeniy291]

low dose accutane mogs. Need to try it out soon

ur 13 no accutane for u

 

[AverageCurryEnjoyer]

ur 13 no accutane for u

wouldnt matter, it doesnt close plates. Rep me as well

 

[org3cel.RR]

Most underrated is unironically Dutasteride.

You dont wanna block dht at 11 tho
Just take them accutane lol, skincare diet habits blah blah allll cope, just take 1 pill and ur good

 

[copercel123]

You dont wanna block dht at 11 tho
Just take them accutane lol, skincare diet habits blah blah allll cope, just take 1 pill and ur good

You don’t want to take accutane at 11 either.

 

[org3cel.RR]

You don’t want to take accutane at 11 either.

Well I did and only made me good, I did accutane from 11 to 12. Literally amazing except the depression part but guess what my skin was glass, then I stopped had a perfect diet and everything absolute trash my skin was dogshit. Hopped on accutane at 15 again and never been better

 

[Balten]

Well I did and only made me good, I did accutane from 11 to 12. Literally amazing except the depression part but guess what my skin was glass, then I stopped had a perfect diet and everything absolute trash my skin was dogshit. Hopped on accutane at 15 again and never been better

Having accutane at young age is fucking stupid idea

 

[org3cel.RR]

Having accutane at young age is fucking stupid idea

No it isnt, no it doesnt close growth plates, no it doesnt reduce testosterone, no it doesnt do any fucking single thing, no fucking side effects

 

[Balten]

No it isnt, no it doesnt close growth plates, no it doesnt reduce testosterone, no it doesnt do any fucking single thing, no fucking side effects

No it isnt, no it doesnt close growth plates, no it doesnt reduce testosterone, no it doesnt do any fucking single thing, no fucking side effects

Real, possible side effects:​

• Dry skin, lips, eyes – nearly universal.
• Liver enzyme elevation.
• Increased triglycerides.
• Mood changes – rare but documented.
• Joint pain, fatigue.
• Photosensitivity.
• Can affect bone growth if taken at very high doses during puberty, but this is rare and dose-dependent.
• Teratogenic (extremely dangerous during pregnancy).

 

[org3cel.RR]

Real, possible side effects:​

• Dry skin, lips, eyes – nearly universal.

Just drink water bud

• Liver enzyme elevation.

• Increased triglycerides.

Just dont take a very high dosage and this only happens if u already have very bad genes for it

• Mood changes – rare but documented.

Muh depression cuck

• Joint pain, fatigue.

All meds do this

• Photosensitivity.

Am I a fucking plant? Bro shut the fuck up

• Can affect bone growth if taken at very high doses during puberty, but this is rare and dose-dependent.

Yeah yeah IFFFFF TAKEN at HIGH dosages bud

• Teratogenic (extremely dangerous during pregnancy).

Am I a women to get pregnant?

You are so fucking retarded, end of debate bud now u were absolutely burned

 

[copercel123]

Well I did and only made me good, I did accutane from 11 to 12. Literally amazing except the depression part but guess what my skin was glass, then I stopped had a perfect diet and everything absolute trash my skin was dogshit. Hopped on accutane at 15 again and never been better

Yes your skin is better but at 11 or even at 15 you heath isn’t.
Accutane affects hormones an at a young age you don’t want it to happen (water), liver damage at 11 isn’t fun bro, it effects bone growth aswell and who tf gave you accutane at 15?!?!

 

[org3cel.RR]

Yes your skin is better but at 11 or even at 15 you heath isn’t.
Accutane affects hormones an at a young age you don’t want it to happen (water), liver damage at 11 isn’t fun bro, it effects bone growth aswell and who tf gave you accutane at 15?!?!

For liver damage you can just support it
Bone growth only on high dosages
And accutane in 11-12 is normal because I started puberty at 11