Sauce99
Iron
- Joined
- Feb 18, 2026
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I’m 16 and planning to start a testosterone cycle, and I’m trying to understand aromatase inhibitors (AIs) before I do anything.
I’m deciding between Arimidex and Aromasin ,and I want to know which one is better overall for managing estrogen (E2) on cycle.
From what I understand, Arimidex is a reversible inhibitor, while Aromasin is irreversible. I’ve also heard people say that after stopping Arimidex, all the estrogen that was suppressed during the cycle can “come back” or rebound. Is this actually true in practice,
Is this actually true, or is it exaggerated? Is the rebound something significant enough to worry about?
On the other hand, Aromasin supposedly has less rebound because it permanently deactivates the aromatase enzyme, but I’ve also heard that it can crash estrogen harder and be more difficult to manage if you take too much.
I’m deciding between Arimidex and Aromasin ,and I want to know which one is better overall for managing estrogen (E2) on cycle.
From what I understand, Arimidex is a reversible inhibitor, while Aromasin is irreversible. I’ve also heard people say that after stopping Arimidex, all the estrogen that was suppressed during the cycle can “come back” or rebound. Is this actually true in practice,
Is this actually true, or is it exaggerated? Is the rebound something significant enough to worry about?
On the other hand, Aromasin supposedly has less rebound because it permanently deactivates the aromatase enzyme, but I’ve also heard that it can crash estrogen harder and be more difficult to manage if you take too much.
