20mg accutane longterm or proper accutane cycle?

[Zagoon]

I usually just have acne come and go every few weeks all resulting in new scars

wondering if i should run 20mg accutane daily for 2 ish years or just do a full cycle over 6 months

 

[amazigh_slayer]

I usually just have acne come and go every few weeks all resulting in new scars

wondering if i should run 20mg accutane daily for 2 ish years or just do a full cycle over 6 months

full cycle is probably smarter, you know what this contains right

 

[dirittomarco]

wondering if i should run 20mg accutane daily for 2 ish years or just do a full cycle over 6 months

same results

 

[Zagoon]

full cycle is probably smarter, you know what this contains right

wdym

 

[amazigh_slayer]

wdym

im asking if you know what a cycle of accutane is

 

[Zagoon]

im asking if you know what a cycle of accutane is

yeah just slowly building it up and getting a cumulative dose of around 12k mg (im 75kg) within 6 months

 

[amazigh_slayer]

yeah just slowly building it up and getting a cumulative dose of around 12k mg (im 75kg) within 6 months

aight that works then its better then just 20mgs overtime if you can handle the sides
because im jewish can u rep my posts and give solution

 

[killuacel]

20mg

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onlinelibrary.wiley.com

 

[Zagoon]

aight that works then its better then just 20mgs overtime if you can handle the sides
because im jewish can u rep my posts and give solution

i would've but this other guy just said 20 now yall gotta fight

 

[amazigh_slayer]

i would've but this other guy just said 20 now yall gotta fight

rep my posts first and then

 

[Zagoon]

rep my posts first and then

did i just get scammed

 

[amazigh_slayer]

i would've but this other guy just said 20 now yall gotta fight

The findings of this cohort study suggest that higher cumulative dosage may potentially reduce risk of acne relapse and isotretinoin retrial.(Source: Acne Relapse and Isotretinoin Retrial in Patients With Acne). 120–150 mg/kg were considered the gold standard cumulative dose, but it depends on the severity of acne (PMID: 26187395). Higher dosages reduce the risk of relapse (High-Dose Isotretinoin Treatment and the Rate of Retrial, Relapse, and Adverse Effects in Patients With Acne Vulgaris). Relapse occurred in 47.4% (CD <200mg/kg) and 26.9% (CD >220mg/kg) of patients. Higher daily doses of Accutane over 6 months were safe and effective, the cumulative dose was around 290 mg/kg, the risk of relapse was reduced to 12.5%.

 

[amazigh_slayer]

The findings of this cohort study suggest that higher cumulative dosage may potentially reduce risk of acne relapse and isotretinoin retrial.(Source: Acne Relapse and Isotretinoin Retrial in Patients With Acne). 120–150 mg/kg were considered the gold standard cumulative dose, but it depends on the severity of acne (PMID: 26187395). Higher dosages reduce the risk of relapse (High-Dose Isotretinoin Treatment and the Rate of Retrial, Relapse, and Adverse Effects in Patients With Acne Vulgaris). Relapse occurred in 47.4% (CD <200mg/kg) and 26.9% (CD >220mg/kg) of patients. Higher daily doses of Accutane over 6 months were safe and effective, the cumulative dose was around 290 mg/kg, the risk of relapse was reduced to 12.5%.

The daily dose is of lesser importance, the main factor is the cumulative dose (Acne Relapse and Isotretinoin Retrial in Patients With Acne). In other clinical observations with a wide range of doses (from very low to high), there was no clear association with relapse if the course was prolonged after clinical improvement.

The classic protocol among dermatologists: start with a low dosage, increase it with the aim of reaching a cumulative dose of 120–150 mg/kg. It works but… Different studies show different figures, but it can be concluded that the daily dosage does not play such a big role, and that a high cumulative dose (220–290 mg/kg) reduces the risk of relapse. If you add a topical retinoid to your routine after an Accutane course, we reduce the risk of relapse to a minimum…

So:Choose your dose individually (you can increase it or stay at the same dose to lower side effects tbh).

Track your cumulative dose (the higher, the better imho) and keep taking isotretinoin until you reach it.

Once you finish isotretinoin, switch to a topical retinoid 2–3 times per week.

written from me in old google doc

 

[Zagoon]

The daily dose is of lesser importance, the main factor is the cumulative dose (Acne Relapse and Isotretinoin Retrial in Patients With Acne). In other clinical observations with a wide range of doses (from very low to high), there was no clear association with relapse if the course was prolonged after clinical improvement.

The classic protocol among dermatologists: start with a low dosage, increase it with the aim of reaching a cumulative dose of 120–150 mg/kg. It works but… Different studies show different figures, but it can be concluded that the daily dosage does not play such a big role, and that a high cumulative dose (220–290 mg/kg) reduces the risk of relapse. If you add a topical retinoid to your routine after an Accutane course, we reduce the risk of relapse to a minimum…

So:Choose your dose individually (you can increase it or stay at the same dose to lower side effects tbh).

Track your cumulative dose (the higher, the better imho) and keep taking isotretinoin until you reach it.

Once you finish isotretinoin, switch to a topical retinoid 2–3 times per week.

written from me in old google doc

so it don't matter what you go with?

 

[amazigh_slayer]

so it don't matter what you go with?

well imo if you focus on culmative dose with higher being the better it works but run a course