Out of curiosity what oral minoxidil dose would you consider sufficient to actually reach that point where the brows/lashes complete enough cycles (like you mentioned: 10–12 months) and potentially become permanent without continued use?
2.5mg is what I'm on. I recommend it. Most commonly formulated too. You get systemic delivery of minoxidil sulfate, reaches peripheral follicles through the bloodstream, allows them to complete multiple rapid cycles 4-6 months IIRC, after 2 full cycles, most them hairs are completely anchored and terminal.
Damn
I haven't even noticed this fast heartrate they always fearmonger. Reminder, it isn't as common as you think.
can i use topical and oral minox together?
Why would you even do this?
i already have 3 bottle of minox
doesn’t furosemide strip away every nutrient in your body
Then use them. If you note it doesn't help, then take oral. Topical is something I don't use simply for the fact it is very variable person-to-person.
im using topical since 2 years, the growth is extremely mid
Then get on oral. You might just be a non-responder. Totally a legitimate reason.
Minoxidil bloat had me contemplating gua Shua lymphatic ultimate debloat challenge shit at 12% bf lmao
Nope.
how do you max out lashes?
Latisee
Btw how long have you used it?
what about the orbital fat loss side
uncommon side effect u won’t get it if u apply it correctly
Off rn
Where’d u get ur hands on BTD PTDM?
It’s a topical solution
But if minoxidil is a vasodilator
TL;DR Not meaningfully.But if minoxidil is a vasodilator
And modafinil is a vasoconstrictor
Wouldn’t that just counter each other to a point
No need for tldr I’ll read every molecule lmaoTL;DR Not meaningfully.
Actually a very good question. But it's a bit more nuanced than "dilator vs constrictor cancel each other out"
I'll explain the mechanism and effect of each and why it doesn't actually matter.
Minox is a vasodilator as you said. It opens K+ channels -> hyperpolarises smooth muscle -> arteriolar vasodilation. Consequently, it lowers peripheral resistance (BP goes down) and improves blood flow. Often causes reflex tachycardia, fluid retention, and maybe even ankle swelling at high doses due to volume shifts.
Modafinil on the other hand is a central stimulant. Activates sympathetic nervous system -> increases norepinephrine -> systemic vasoconstriction. Thus causes a slight increase in BP, HR, and peripheral vasoconstriction. The focus is central, improving wakefulness and alertness. It doesn't target vasculature directly.
Sure, modafilin adds a vasoconstrictive push, but it's mild and centrally mediated. Oral minox's vasodilation is direct and pharmacological, stronger, and more targeted to arteriolar beds. You're not getting a cancel-out. Instead, modafilin might slightly blunt the drop in BP, or lesson edema (a good thing, who wants that fucking bloat??)
Using oral minox at even 1.25mg/day up to 5mg/day with modafinil will not cause any of them to meaningfully affect one another. If anything, you'll just remove the bloat.
I know @chadisbeingmade and @Jonasㅤㅤ⠀ hate minox, or at least oral, but I don't think it's so bad. Although it gets a bad rep due to Norwood Reaper victims.
It's so insignificant that it would be ignored clinically.
You have a minox bloat or in general it doesn't do much?
ever consider telimisartin too?
have u ran the lithium carbonate? I assume its for wnt/beta catenin pathway ye? lmk I wanna start using it soon
