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beachflow83
Iron
- Joined
- Nov 18, 2025
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Okay so just to set a timeline i started both isotretinoin and topical minoxidil for severe acne and androgenic alopecia in January of 2024.
As of the last test i have 30 nmol/L testosterone with a fairly high 22% body fat at that time so with proper body fat even higher naturally. From both sides of my family i inherited early AGA. I added oral finasteride by the end of february, temples fully regrew after 4-5 months so around May.
After i stopped accutane because my cycle was over (i took daily 2x20mg for 6 months) after a month or so in around august my temples went back to baseline even though i didn’t change dose or treatment.
There are 2 important facts to mention:
1. Temples have high DHT enzyme type I and type II activity
2. Accutane lowers Type 1 5α-reductase activity by ~50–70% in the skin
My theory is that accutane actually could have strongly contributed to my full temple recovery by blocking type 1 dht while finasteride blocked type 2, pretty much what just doing dutasteride would have done. While the thinned crown and frontal scalp fully recovered on fin temple relapse perfectly aligned with the discontinuation of accutane. 2 weeks ago started dutasteride so will see if my temples gets fully fixed or not.
TLDR: Accutane could indirectly help with temple regrowth in early stages of androgenic alopecia by blocking type I enzyme in the temples
As of the last test i have 30 nmol/L testosterone with a fairly high 22% body fat at that time so with proper body fat even higher naturally. From both sides of my family i inherited early AGA. I added oral finasteride by the end of february, temples fully regrew after 4-5 months so around May.
After i stopped accutane because my cycle was over (i took daily 2x20mg for 6 months) after a month or so in around august my temples went back to baseline even though i didn’t change dose or treatment.
There are 2 important facts to mention:
1. Temples have high DHT enzyme type I and type II activity
2. Accutane lowers Type 1 5α-reductase activity by ~50–70% in the skin
My theory is that accutane actually could have strongly contributed to my full temple recovery by blocking type 1 dht while finasteride blocked type 2, pretty much what just doing dutasteride would have done. While the thinned crown and frontal scalp fully recovered on fin temple relapse perfectly aligned with the discontinuation of accutane. 2 weeks ago started dutasteride so will see if my temples gets fully fixed or not.
TLDR: Accutane could indirectly help with temple regrowth in early stages of androgenic alopecia by blocking type I enzyme in the temples
