Anyone actually tried Kisspeptin (KP-10) for T levels?

[MakinItHappen]

Does anyone here has real-world experience running Kisspeptin-10 to boost testosterone?

Could it be a clean alternative to shutting down your own production with TRT? Theoretically, hitting the KISS1R receptors to pulse GnRH should signal LH and tell the Leydig cells to get to work for testosterone production, all-the-while keeping your fertility intact?

Seems like it could be a cleaner, though probably less powerful, alternative to actual TRT if you don't want to become Clavicular lol.

 

[MakinItHappen]

 

[Itsov3rlol]

Im searching about this on meso rx

 

[moliuny]

@nwed

Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men - PubMed

Kisspeptin-10 boluses potently evoke LH secretion in men, and continuous infusion increases testosterone, LH pulse frequency, and pulse size. Kisspeptin analogues have therapeutic potential as regulators of LH and thus testosterone secretion.

pubmed.ncbi.nlm.nih.gov

Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism - PubMed

Kisspeptin-10 administration increased LH pulse frequency and LH secretion in hypotestosteronaemic men with T2DM in this proof-of-concept study, with associated increases in serum testosterone. These data suggest a potential novel therapeutic role for kisspeptin agonists in enhancing endogenous...

pubmed.ncbi.nlm.nih.gov