Anyone been on MT2 long term? Is it safe?

[Deleted member 319009]

MT2 sounds interesting. Tan + lowering the tism + libido

But do you get disgusting moles? Or cancer?

 

[aids]

MT2 sounds interesting. Tan + lowering the tism + libido

But do you get disgusting moles? Or cancer?

We can safely discern you are a retard that follows TikTok information.
Next time DYOR instead of perpetuating bullshit that just isn't true.

 

[Deleted member 319009]

We can safely discern you are a retard that follows TikTok information.
Next time DYOR instead of perpetuating bullshit that just isn't true.

Why are you so touchy? Stop bone smashing your brain

Melanocortin agonism in a social context selectively activates nucleus accumbens in an oxytocin-dependent manner

Social deficits are debilitating features of many psychiatric disorders, including autism. While time-intensive behavioral therapy is moderately effec…

www.sciencedirect.com

Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism - PMC

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social interactions, difficulty with communication, and repetitive behavior patterns. In humans affected by ASD, there is a male pre-disposition ...

pmc.ncbi.nlm.nih.gov

Those studies show MT2 affects the oxytocin reward circuit and can improve autistic behaviours in mice. Not that far fetched it could have a similar effect in people. It's worth a go, specially when there's a bunch of anecdotes of people feeling more sociable on MT2.

 

[aids]

Why are you so touchy? Stop bone smashing your brain

Melanocortin agonism in a social context selectively activates nucleus accumbens in an oxytocin-dependent manner

Social deficits are debilitating features of many psychiatric disorders, including autism. While time-intensive behavioral therapy is moderately effec…

www.sciencedirect.com

Melanotan-II reverses autistic features in a maternal immune activation mouse model of autism - PMC

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social interactions, difficulty with communication, and repetitive behavior patterns. In humans affected by ASD, there is a male pre-disposition ...

pmc.ncbi.nlm.nih.gov

Those studies show MT2 affects the oxytocin reward circuit and can improve autistic behaviours in mice. Not that far fetched it could have a similar effect in people. It's worth a go, specially when there's a bunch of anecdotes of people feeling more sociable on MT2.

Stop linking studies you haven't fucking read to try and prove to me some bullshit you are incorrect on.

MT2 has lesser affinity for the MC4R than a selective MC4R agonist as it was developed for MC1R agonism specifically.
Using MT2 for some bullshit pertaining to oxytocin is like using tren to feel confident.
Fuck off.

 

[Deleted member 319009]

Stop linking studies you haven't fucking read to try and prove to me some bullshit you are incorrect on.
View attachment 4567216
MT2 has lesser affinity for the MC4R than a selective MC4R agonist as it was developed for MC1R agonism specifically.
Using MT2 for some bullshit pertaining to oxytocin is like using tren to feel confident.
Fuck off.

“Selective MC4R agonist is more selective” no shit you're shadowboxing lad

I never said MT2 > a selective MC4R agonist or that it’s some precision oxytocin drug. I’m talking about the combo: tan + libido + maybe social. MT-II has rodent data (oxytocin-dependent NAc Fos in a social context, and improved autism like social deficits in an MIA mouse model).
And yeah, there are anecdotes of people feeling more social on MT2 — not proof, but at least plausible given the animal data. Your selective agonist gonna tan you too?

I'm done chatting with you lad, you clearly have high estrogen to be getting this emotional. "Fuck off." hahahah

 

[aids]

“Selective MC4R agonist is more selective” no shit you're shadowboxing lad

I never said MT2 > a selective MC4R agonist or that it’s some precision oxytocin drug. I’m talking about the combo: tan + libido + maybe social. MT-II has rodent data (oxytocin-dependent NAc Fos in a social context, and improved autism like social deficits in an MIA mouse model).
And yeah, there are anecdotes of people feeling more social on MT2 — not proof, but at least plausible given the animal data. Your selective agonist gonna tan you too?

I'm done chatting with you lad, you clearly have high estrogen to be getting this emotional. "Fuck off." hahahah

If you are going to argue with me, don't write two sentences that encase an AI-generated response you've copy-pasted.
And then you have the audacity to project your retardation onto me JFL

 

[Deleted member 319009]

If you are going to argue with me, don't write two sentences that encase an AI-generated response you've copy-pasted.
And then you have the audacity to project your retardation onto me JFL

English is not my first language retard, I got AI to translate it. What's your excuse for being this touchy?

 

[aids]

“Selective MC4R agonist is more selective” no shit you're shadowboxing lad

I never said MT2 > a selective MC4R agonist or that it’s some precision oxytocin drug. I’m talking about the combo: tan + libido + maybe social. MT-II has rodent data (oxytocin-dependent NAc Fos in a social context, and improved autism like social deficits in an MIA mouse model).
And yeah, there are anecdotes of people feeling more social on MT2 — not proof, but at least plausible given the animal data. Your selective agonist gonna tan you too?

I'm done chatting with you lad, you clearly have high estrogen to be getting this emotional. "Fuck off." hahahah

Stop linking studies you haven't fucking read to try and prove to me some bullshit you are incorrect on.
View attachment 4567216
MT2 has lesser affinity for the MC4R than a selective MC4R agonist as it was developed for MC1R agonism specifically.
Using MT2 for some bullshit pertaining to oxytocin is like using tren to feel confident.
Fuck off.

Further, to clarify my claims because you are a retard.
MT2 can still have higher affinity for the MC4R than a selective MC4R agonist. The point is that it has low affinity for the MC4R relative to a selective MC4R agonist. So your theories are just that, theories.
Affinity and selectivity are not synonymous. You obviously can't understand that though because you are a retard for the reasons aforementioned.
MT2 would have a use case if it had high affinity for other receptors but if your use case involves libido or to not be an autistic faggot, then there's no hope for you.

 

[aids]

English is not my first language retard, I got AI to translate it. What's your excuse for being this touchy?

Then go to the subforums for your language. I don't want to argue with a gremlin that can't speak English properly hence perpetuating shitty arguments and using AI to translate for him.
Seems like you can speak pretty clear English even featuring informal colloquialisms so I don't understand why you'd need it for a formal response pertaining to the actual topic we're discussing => you're a liar that didn't think he'd get caught out for relying on AI for his arguments.
Again, go fuck off. And to clarify:

I'm done chatting with you lad, you clearly have high estrogen to be getting this emotional. "Fuck off." hahahah

I have absolutely zero negative emotion right now, but I am being emphatic because I do not want people like you flooding the forum with your shitty theories thereby just perpetuating incorrect/misleading information.

 

[Deleted member 319009]

Further, to clarify my claims because you are a retard.
MT2 can still have higher affinity for the MC4R than a selective MC4R agonist. The point is that it has low affinity for the MC4R relative to a selective MC4R agonist. So your theories are just that, theories.
Affinity and selectivity are not synonymous. You obviously can't understand that though because you are a retard for the reasons aforementioned.
MT2 would have a use case if it had high affinity for other receptors but if your use case involves libido or to not be an autistic faggot, then there's no hope for you.

I genuinely don’t get what you’re missing: rodent data + anecdotes = plausible, not proven. I never claimed it’s a human ASD treatment. You’re just emotional for some reason.

I used AI to translate it again, don't be upset about it

 

[iwantuinsideme]

the answer is no, you shouldn't be on it long term and this is why effectual drugs get banned because of retarded no hopers like you.

it's a tanning drug which means you produce more melanin, and that allows you to tan if you put your skin the sun microwave. taking it without the sun is less effectual than taking a tiny dose of steroids, not eating at all and never working out. you're not getting bigger. so you take it 1-2 weeks before you rape your skin with the sun and then do that.

side effects include increased libido and eppetite supression and development of moles.

if you're taking it long run it's completely ineffectual unless you're in the sun all the time which you wont be - and you're likely going to just be moley mcmoley. and yes you do develop moles ime - even if using for a few weeks, you'll get some.

the other problems with it are:
it's not the drug per se but the sun - you're aging yourself, there is no safe natural tan. now i actually think mt2 is excellent vs being a normie retard if you are going on a beach holiday and it seems as though you'll do yourself marginally less sun damage, but the best thing is not to expose yourself in the first place.

you will find out in time - it's not cancer, it's the destruction of your collagen which means the skin looks shit and will be prone to wrinkling.

also tans fade. they last for a bit, but it fades. it's not like you go super dark for life. although i have seen that old moreplatesmoredates video where he claims he was perma darker, but ime not true, didn't happen for me