anyone got a clue on how to home brew ghk-cu serum?

[Deleted member 86562]

im gonna use it instead of hyaluronic acid when I microneedle so the machine glides on my skin. Can I just mix pure ghk-cu powder with pbs and call it a day?

 

[LwsP7]

Do you not need BAC water or something

 

[Deleted member 86562]

Do you not need BAC water or something

im not planning on injecting it

 

[imontheloose]

Okay, you can. But you might want to add a sort of gel to it so it spreads nice. 0.05-0.1% w/v is typical.

 

[Deleted member 86562]

for anyoe wondering I found a real recipe for a home made serum
1. dissolve ghk-cu powder in pbs
2. gently stir glycerin and 1% hyaluronic acid into the solution
3. add preservatives (this one is safe from 0,1-0,5% Liquid Germall Plus)
4. check the ph


might need to change it to match the recipe they used in the studies

 

[imontheloose]

for anyoe wondering I found a real recipe for a home made serum
1. dissolve ghk-cu powder in pbs
2. gently stir glycerin and 1% hyaluronic acid into the solution
3. add preservatives (this one is safe from 0,1-0,5% Liquid Germall Plus)
4. check the ph


might need to change it to match the recipe they used in the studies

Nigga revoked my solution.

 

[Deleted member 86562]

Nigga revoked my solution.

Ye suck it up boss

 

[Deleted member 157297]

for anyoe wondering I found a real recipe for a home made serum
1. dissolve ghk-cu powder in pbs
2. gently stir glycerin and 1% hyaluronic acid into the solution
3. add preservatives (this one is safe from 0,1-0,5% Liquid Germall Plus)
4. check the ph


might need to change it to match the recipe they used in the studies

yeah that recipe’s not bad on paper, but it’s still kinda barebones compared to what’s used in actual research formulations.
the main issue is stability. GHK-Cu oxidizes super easily, especially once mixed with HA or glycerin. PBS + glycerin + HA sounds nice for texture, but it’s not ideal for keeping the peptide active long term.
here’s how i’d tweak it if you actually wanna make something close to study-grade:
dissolving:
dissolve your GHK-Cu in sterile distilled water or bacteriostatic water first, not straight PBS. then slowly add a phosphate or HEPES buffer to bring pH around 6.5-7.0 (that’s the sweet spot for peptide stability).
mixing:
after it’s fully dissolved, add your 1% HA (make sure it’s sodium hyaluronate, not the cosmetic gel type). add glycerin after HA is dispersed, around 2-5% of total volume is enough for glide.
preservation:
Liquid Germall Plus is fine at 0.3-0.5%, just make sure your total solution stays below 50C while mixing; heat kills it. mix gently, don’t shake peptides denature from bubbles and shear stress.
storage
store in small 5-10mL vials, airtight, dark, and cold (fridge at minimum). don’t make huge batches. Once you open a vial, it’s good for maybe 7-10 days tops.
optional but ideal: add a tiny bit of EDTA (0.01-0.05%) helps keep copper bound properly and prevents oxidation.

the recipe works as a starting point, but it’s more like a quick DIY version. if you want it to actually perform like the GHK-Cu used in studies, you gotta be precise about pH, buffering, and oxidation control. otherwise half your peptide will be dead before it even touches your skin.

 

[homer2000]

yeah that recipe’s not bad on paper, but it’s still kinda barebones compared to what’s used in actual research formulations.
the main issue is stability. GHK-Cu oxidizes super easily, especially once mixed with HA or glycerin. PBS + glycerin + HA sounds nice for texture, but it’s not ideal for keeping the peptide active long term.
here’s how i’d tweak it if you actually wanna make something close to study-grade:
dissolving:
dissolve your GHK-Cu in sterile distilled water or bacteriostatic water first, not straight PBS. then slowly add a phosphate or HEPES buffer to bring pH around 6.5-7.0 (that’s the sweet spot for peptide stability).
mixing:
after it’s fully dissolved, add your 1% HA (make sure it’s sodium hyaluronate, not the cosmetic gel type). add glycerin after HA is dispersed, around 2-5% of total volume is enough for glide.
preservation:
Liquid Germall Plus is fine at 0.3-0.5%, just make sure your total solution stays below 50C while mixing; heat kills it. mix gently, don’t shake peptides denature from bubbles and shear stress.
storage
store in small 5-10mL vials, airtight, dark, and cold (fridge at minimum). don’t make huge batches. Once you open a vial, it’s good for maybe 7-10 days tops.
optional but ideal: add a tiny bit of EDTA (0.01-0.05%) helps keep copper bound properly and prevents oxidation.

the recipe works as a starting point, but it’s more like a quick DIY version. if you want it to actually perform like the GHK-Cu used in studies, you gotta be precise about pH, buffering, and oxidation control. otherwise half your peptide will be dead before it even touches your skin.

js uploaded a better guide -> GHK-Cu Topical Serum Instructions