Anyone have experience with Lasix?

[raspberryfart]

What are your thoughts on Lasix?

 

[IanIachimoe2491]

great shit

 

[jotunnr]

What are your thoughts on Lasix?

its ass i got ototoxicity and 10 other mineral deficiencies

switch to eplerenone

 

[raspberryfart]

its ass i got ototoxicity and 10 other mineral deficiencies

switch to eplerenone

How often did you use it?

 

[jotunnr]

great shit

 

[jotunnr]

How often did you use it?

only on special occasions, its dogshit

 

[Ahmed88]

Great shit, debloats you hard, has basically no sides aslong as you aren't retarded enough

It's ass switch to eplerenone

Fucking retard

 

[raspberryfart]

Great shit, debloats you hard, has basically no sides aslong as you aren't retarded enough

Fucking retard

Whats the safest way to take it? Im thinking no more than 3 times a month but Ill probably use less than that honestly.

 

[jotunnr]

has basically no sides aslong as you aren't retarded enough

Nigga what???

Lasix side effects

Eplerenone side effects

Both end up debloating you regardless, good luck performing dialysis for the rest of your life tho

 

[jotunnr]

Whats the safest way to take it? Im thinking no more than 3 times a month but Ill probably use less than that honestly.

Dont take this fucking garbage man, if you want to stay debloated permanently with minimal-zero risk switch to eplerenone, literally nobody uses lasix

It's a temporary thing that you use on special occasion and that's it, not something consistent

 

[raspberryfart]

Dont take this fucking garbage man, if you want to stay debloated permanently with minimal-zero risk switch to eplerenone, literally nobody uses lasix

It's a temporary thing that you use on special occasion and that's it, not something consistent

Thanks ill def check it out. I already ordered the lasix though but im only planning on using it on very special occasions.

 

[Ahmed88]

Whats the safest way to take it? Im thinking no more than 3 times a month but Ill probably use less than that honestly.

You could go higher. People fearmonger furosemide way too much. You can dose up to 120mg, but the main thing is keeping your electrolytes in check and monitoring your blood pressure and for any symptoms of dehydration or dizziness.

Mark as solution by pressing the checkmark ->

Both end up debloating you regardless

No, they don’t, you fucking retarded faggot. Eplerenone blocks aldosterone from binding to the mineralocorticoid receptor. Aldosterone is just one of many pathways that regulate sodium reabsorption. Unless someone has excess aldosterone activity, blocking it has a relatively modest effect because the body compensates through other mechanisms.


On top of that, the vast majority of sodium is reabsorbed before the late distal tubule and collecting duct, the part of the nephron where aldosterone acts. By the time the filtrate reaches that segment, only about 2–3% of filtered sodium remains to be fine-tuned. That’s why eplerenone is a relatively weak diuretic, even in people who benefit from it.

I don't want you talking bullshit every again faggot, delete your account

 

[jotunnr]

You could go higher. People fearmonger furosemide way too much. You can dose up to 120mg, but the main thing is keeping your electrolytes in check and monitoring your blood pressure and for any symptoms of dehydration or dizziness.

Mark as solution by pressing the checkmark ->


No, they don’t, you fucking retarded faggot. Eplerenone blocks aldosterone from binding to the mineralocorticoid receptor. Aldosterone is just one of many pathways that regulate sodium reabsorption. Unless someone has excess aldosterone activity, blocking it has a relatively modest effect because the body compensates through other mechanisms.


On top of that, the vast majority of sodium is reabsorbed before the late distal tubule and collecting duct, the part of the nephron where aldosterone acts. By the time the filtrate reaches that segment, only about 2–3% of filtered sodium remains to be fine-tuned. That’s why eplerenone is a relatively weak diuretic, even in people who benefit from it.

I don't want you talking bullshit every again faggot, delete your account

"People fearmonger furosemide way too much" I'm telling you right now mate I dosed up to 80mg kept my electros in check monitored my blood pressure and still ended up with ototoxicity.

Aldosterone and ADH are the primary hormones for water retention, E2, sodium permeability and everything else play a much milder effect.

Consistent use of eplerenone will drop you down a couple lbs of water weight with relatively low-zero risk at all. Yes it's a weak diuretic but unless you're a bloat monster like lucasegolifts you don't need anything more in the long run

Lasix is not a diuretic that you can take consistently, and you can't prevent ototoxicity.

"Mark as solution by pressing the checkmark"

 

[Ahmed88]

"People fearmonger furosemide way too much" I'm telling you right now mate I dosed up to 80mg kept my electros in check monitored my blood pressure and still ended up with ototoxicity.

Yeah, you’re a fucking braindead retard.


Ototoxicity with furosemide is fucking rare as shit, it’s as low as 1% according to some studies, and the highest reported cases are 6% and almost all of them say close to every single case is reversible, you apebrained nigger. That shit only happens in severe/high doses, rapid IV administration, kidney impairment, or other risk factors.

Aldosterone and ADH are the primary hormones for water retention, E2, sodium permeability and everything else play a much milder effect.

Consistent use of eplerenone will drop you down a couple lbs of water weight with relatively low-zero risk at all. Yes it's a weak diuretic but unless you're a bloat monster like lucasegolifts you don't need anything more in the long run

Lasix is not a diuretic that you can take consistently, and you can't prevent ototoxicity.

"Mark as solution by pressing the checkmark"

You have no fucking clue what you’re talking about, you clueless fagtard .





Eplerenone blocks the mineralocorticoid receptor, but aldosterone is only one goddamn component of sodium homeostasis, you moron. The kidney reabsorbs roughly 98–99% of filtered sodium before the late distal tubule and collecting duct, which is where aldosterone primarily acts via ENaC. That segment only fine-tunes the final 1–2% of sodium excretion rather than controlling the bulk of sodium handeling.





On top of that, chronic mineralocorticoid receptor blockade triggers a bunch of compensatory mechanisms that fuck your whole theory over. Renin and angiotensin II spike like crazy, sympathetic activity ramps up, and sodium reabsorption through aldosterone-independent transporters gets upregulated hard.

That’s well-established renal physiology, you fucking faggot, and exactly why eplerenone is classified as a weak-ass diuretic.

The rest of what you’re claiming is total bullshit and isn’t backed by any good evidence. There are no high-quality human studies showing that healthy people taking eplerenone chronically remain several pounds lighter from water alone, you deluded fuck. Even in people who need it, it only produces an initial natriuresis, but over time sodium excretion returns to match sodium intake as a new steady state is reached.