anyone here tried dihexa?

[iblameautistickids]

been looking into it anyone here tried it

 

[iblameautistickids]

bump

 

[xlimz]

dih

 

[iblameautistickids]

dih

deriod

 

[iblameautistickids]

bump

 

[aids]

ACD856 or LDAR.

 

[iblameautistickids]

ACD856 or LDAR.

whats that never heard of it

 

[ASM5]

been looking into it anyone here tried it

have some coming td actually ill let you know

 

[iblameautistickids]

have some coming td actually ill let you know

Whats ur protocol with it

 

[iblameautistickids]

have some coming td actually ill let you know

Bookmark this post and tag me when u tried it brah

 

[Orthognathic]

been looking into it anyone here tried it

Honestly, I don't know much about it but what I've read about it so far makes me very skeptical.

Dihexa works by modulating HGF/c-Met signaling which is proven to be strongly linked with cancer cell growth, as well as the fact that c-Met plays a huge role in vascular remodeling & angiogenis. Disrupting it could result in a large plethora of cardiovascular issues

Not to mention that enhancing your brains neuroplasticity beyond your bodies natural capabilities will probably worsen or cause ocd, anxiety, psychosis, and just a lot of pretty fucked mental effects

 

[iblameautistickids]

Honestly, I don't know much about it but what I've read about it so far makes me very skeptical.

Dihexa works by modulating HGF/c-Met signaling which is proven to be strongly linked with cancer cell growth, as well as the fact that c-Met plays a huge role in vascular remodeling & angiogenis. Disrupting it could result in a large plethora of cardiovascular issues

Not to mention that enhancing your brains neuroplasticity beyond your bodies natural capabilities will probably worsen or cause ocd, anxiety, psychosis, and just a lot of pretty fucked mental effects

Not sure about the stuff u said but the anacdotes I’ve seen about it seems to be very good, I’ve seen people who use it to help there depression, anxiety and autism (not gonna cure but helps) I’ll try to find the posts about it later

 

[´´´´´´´´]

You probably don’t need it. Why is it you wanna try?

 

[iblameautistickids]

You probably don’t need it. Why is it you wanna try?

I wanna experiment with it for studying and heard it has a dopamergic effect (which I need tbh), still doing my research on it doe

 

[Orthognathic]

Not sure about the stuff u said but the anacdotes I’ve seen about it seems to be very good, I’ve seen people who use it to help there depression, anxiety and autism (not gonna cure but helps) I’ll try to find the posts about it later

Science > anecdotes any day of the week, rule of thumb is to follow scientific evidence that aligns with anecdotes. Hope all goes well for you brother

 

[slaters]

ACD856 or LDAR.

Curiosity is ascending

 

[´´´´´´´´]

I wanna experiment with it for studying and heard it has a dopamergic effect (which I need tbh), still doing my research on it doe

Adderall

 

[ASM5]

Whats ur protocol with it

 

[ASM5]

Bookmark this post and tag me when u tried it brah

gotchu I kind of phrased this bad since its just for me to understand its not a full guide but it does cover my complete stack

 

[enchanted_elixir]

I recommend using strong neurotrophins only if you also are doing neurogenic activities (ex. learning hard stuff, using your mind in novel ways)

 

[iblameautistickids]

gotchu I kind of phrased this bad since its just for me to understand its not a full guide but it does cover my complete stack

thanks brah ill look into it later

 

[iblameautistickids]

I recommend using strong neurotrophins only if you also are doing neurogenic activities (ex. learning hard stuff, using your mind in novel ways)

what neurotrophins do u reccomend

 

[kingofkings]

It works best when there’s actual damage to the brain. In mice studies it helped restore memory function in mice with artificially induced problems similar to alzheimers. But what’s really interesting is that in healthy mice, it doesn’t improve memory or seem to have any noticeable effect.

If you want a nootropic, try Lions Mane. Doesn't work for everyone but for me it has a pronounced effect. Mind you, you need a good source.

 

[enchanted_elixir]

what neurotrophins do u reccomend

Dihexa, Cerebrolysin.

 

[ASM5]

Dihexa, Cerebrolysin.

Cerebrolysin is cope its been debunked

 

[enchanted_elixir]

Cerebrolysin is cope its been debunked

How? Why?

 

[slaters]

How? Why?

A couple people say it’s just some bullshit that’s being pushed by a company I never looked into it though

 

[ASM5]

How? Why?

https://moreisdifferent.blog/p/wth-is-cerebrolysin-actually read this it does a pretty good job explaining why

 

[Kelly Oubre Jr]

 

[enchanted_elixir]

https://moreisdifferent.blog/p/wth-is-cerebrolysin-actually read this it does a pretty good job explaining why

I don't feel like reading this so now I must edit my perception of Cerebrolysin to "confident in its effects, but opinion ultimately undecided due to pending data to review"

 

[ASM5]

I don't feel like reading this so now I must edit my perception of Cerebrolysin to "confident in its effects, but opinion ultimately undecided due to pending data to review"

yeah I read half of it and got bored lmao

 

[ASM5]

I don't feel like reading this so now I must edit my perception of Cerebrolysin to "confident in its effects, but opinion ultimately undecided due to pending data to review"

Also btw is dihexa actually likely to cause cancer or should I be fine if I cycle on 3 weeks 4 off. In rat studies they they only tested them for 2-3 weeks they were all short term studies, so the long term effects are unclear. Was wondering if you had any anecdotal evidence.

 

[enchanted_elixir]

Also btw is dihexa actually likely to cause cancer or should I be fine if I cycle on 3 weeks 4 off. In rat studies they they only tested them for 2-3 weeks they were all short term studies, so the long term effects are unclear. Was wondering if you had any anecdotal evidence.

I don't know enough about Dihexa's mechanism of action to say anything worth your time, to be fair.

 

[CD34]

There was a really high iq brainmaxxing thread over here , there was everything explained

 

[fika2]

@ASM5 all of this just to get mogged by adderall, and caffeine

 

[CD34]

Neuroprotection and Recovery

• ARA-290: Enhances nerve fiber growth, reduces pain in various diseases.
• BPC-157: Repairs dopaminergic neurons, increases Nitric oxide.
• Cortagen: Aids posttraumatic recovery of peripheral nerve tissue.
• Cerebrolysin, N-PEP-12: Provides essential neurotrophic factors, enhances brain oxygen delivery.
• Cerluten: Regulates CNS, acts as antioxidant and adaptogen.
• Cortexin: Balances cortisol, boosts serotonin, GABA, and dopamine regulation.
• Dihexa: Stimulates synapse generation, potentially improving memory and motor functions.
• DNSP-5 & 11: Protects dopaminergic neurons, enhances motor performance.
• Glutathione: Combats oxidative stress in Parkinson’s disease.
• HAYED (5): Reduces oxidative damage in cells and brain.
• Humanin: Protects against neurotoxins, enhances neurological insulin sensitivity.
• Melanotan 1 & 2: Reduces neural inflammation, improves astrocyte function.
• Pinealon: Repairs neurologic and pituitary damage, improves circadian rhythms.
• Thymosin alpha-1, Thymosin Beta 4: Supports neuron growth and connectivity, reduces inflammation.
• WRW-4: Protects brain from amyloid β42 impairment.

Neurogenesis and Cognitive Enhancement

• FGLL/HA-FGL: Stimulates neurite outgrowth, reduces oxidative stress-induced neuronal death.
• GHK-Cu: Enhances angiogenesis and nerve growth, reduces CNS inflammation.
• IGF-2: Involved in myelinogenesis, neuronal growth, and memory improvement.
• P21: Mimics LIF, inhibits tau hyperphosphorylation, enhances neurogenesis.
• Rubiscolin-6, Semax: Stimulates memory consolidation, induces neurotrophic factors.
• Tesamorelin: Increases NAAG levels, potentially enhancing cognitive function.

Regulatory and Signaling Pathways

• Epitalon (Epithalamin): Increases stress resistance, acts as antioxidant.
• Fermented rice peptide (FRP): Regulates ERK/CREB/BDNF signaling, memory function.
• GLP-1: Protects neurons, stimulates neurite outgrowth, reduces amyloid-beta levels.
• Gly-Pro-Glu (GPE): Modulates signaling pathways, facilitates dopamine release.
• Gonadorelin: Modulates testosterone levels, affecting neuroprotection.
• Mots-C: Sensitizes endothelial cells to signaling molecules.
• Noopept: Affects NGF and BDNF expression, enhances adaptation to environmental stress.
• Orexin-A: Improves memory tasks performance in sleep-deprived subjects.
• Phoenixin: Involved in regulation of memory, anxiety, and reproductive function.
• VGVAPG (pal-VGVAPG): Modulates astrocyte and neuroblastoma cell functions.
• VIP: Neuroprotective against inflammatory conditions, promotes repair and BDNF production.

Specialized Functions and Conditions

• Thyrotropin TRH: Facilitates motor learning, decreases ataxia in degenerative diseases.

---

Full list

• ARA-290 increases the number of small nerve fibers and reduces pain significantly, offering effective treatment for nerve damage seen in diseases like sarcoidosis, diabetes, thyroid dysfunction, celiac disease, HIV, and more. Dr. Daniel Culver states, "ARA 290 offers new hope for patients suffering debilitating pain and severe dysautonomia."
• BPC-157 repairs dopaminergic neurons and raises Nitric oxide levels.
• Cortagen demonstrated a pronounced therapeutic effect upon the structural and functional posttraumatic recovery of peripheral nerve tissue.
• Cerebrolysin (to a weaker extent N-PEP-12) contains GDNF, NGF, BDNF, CTNF, and many essential amino acids, encouraging more oxygen delivery into the brain.
• Cerluten helps regulate the CNS and cortex, acting as a neural antioxidant and perhaps as an adaptogen.
• Cortexin comprises BDNF and NGF peptides, reduces excessive levels of cortisol, and enhances serotonin and GABA production. Stimulates dopamine liberation and suppresses dopamine action on receptors.
• Dihexa is a hepatocyte growth factor agonist that stimulates nerve synapse generation, potentially overcoming memory and motor dysfunctions.
• DNSP-5 & 11 increase tyrosine hydroxylase positive neuronal sparing, enhance motor performance, and induce neurological GDNF(?), protecting dopaminergic neurons.
• Epitalon (A.K.A. Epithalamin) increases resistance to emotional stress and acts as an antioxidant.
• Fermented rice peptide (FRP)prevents memory impairment through regulation of the ERK/CREB/BDNF signaling pathway, decreasing acetylcholine levels and increasing acetylcholinesterase activity.
• FGLL/HA-FGL activates NCAM–FGFR signaling pathways, resulting in increased neurite outgrowth and survival, effects in memory, and decreased oxidative stress-induced neuronal cell death.
• GHK-Cu improves angiogenesis in the nervous system, boosts nerve outgrowth, and reduces inflammation in the central nervous system.
• GLP-1 protects against excitotoxic neuron damage and stimulates neurite outgrowth, reducing levels of amyloid-beta and the beta-amyloid precursor protein.
• Glutathione may combat oxidative stress that damages dopamine neurons in Parkinson’s disease.
• Gly-Pro-Glu (GPE) is neuroprotective, modulating calcium and GSK-3β signaling, facilitating dopamine release through NMDA receptor interaction.
• Gonadorelin raises LH, converting into testosterone, which contains neuroprotective effects against Dementia. Continuous use requires cycling due to natural testosterone shutdown.
• HAYED (5) decreases iron and radical levels, preventing cell and brain damage.
• Humanin protects the brain from neurotoxins like amyloid β, improves neurological insulin sensitivity, regulates IRS-1/mTOR signaling, and acts like an antioxidant to excitotoxins.
• IGF-2 plays a role in myelinogenesis, regulating growth, differentiation, survival of neurons, calcium homeostasis, and acetylcholinesterase enhancement.
• Melanotan 1 & 2 assist with neural inflammation and improve astrocyte functioning by increasing levels of BDNF.
• Mots-C sensitizes endothelial cells to effects of other signaling molecules like acetylcholine.
• Noopept positively affects psychological components for rapid climate adaptation, expression of NGF and BDNF mRNA, and increases DNA-binding activity of HIF-1.
• Orexin-A significantly improves performance in sleep-deprived subjects on short-term memory tasks.
• P21 is a LIF mimetic, inhibiting tau abnormal hyperphosphorylation, enhancing adult hippocampal progenitors proliferation and differentiation, and improving cognition.
• Phoenixin plays a role in reproductive function, memory, and anxiety regulation in the brain and periphery.
• Pinealon mends dopaminergic/serotonergic and pituitary damage caused by aging, may improve circadian rhythm disorders, and limits excitotoxic effects of NMDA activity.
• Rubiscolin-6 had an analgesic effect and stimulated memory consolidation.
• Semax, induces BDNF in the CNS, and improves gene expression for the hippocampus and frontal cortex, preventing long-term potentiation impairment.
• Tesamorelin raises NAAG levels.
• Thymosin alpha-1 advances neuron growth and development connections between neurons, protective for inflammation and neuron dysfunction.
• Thymosin Beta 4 might improve spinal cord wounds, promoting angiogenesis, neurogenesis, synaptogenesis, and oligodendrogenesis.
• Thyrotropin TRH enhances motor learning speed via exogenous administration, active in the cerebellum, and decreases ataxia in cerebellar degenerative disease models.
• VIP has a neuroprotective effect on inflammatory conditions, inhibiting production of microglia-derived proinflammatory factors and promoting axonal regrowth and BDNF production through the VPAC2 receptor.
• VGVAPG (sold as pal-VGVAPG) decreases secretion of P4 by astrocytes and SH-SY5Y Neuroblastoma cells proliferation, which is prevented by ROS scavenger N-acetyl-L-cysteine.
• WRW-4 protests the brain from amyloid β42 impairment, acting as a FPR2 antagonist

 

[User28823]

great for brain cancer

 

[ASM5]

M

@ASM5 all of this just to get mogged by adderall, and caffeine

Aderall is neurotoxic over time and I’ll be taking caffeine on occasion.

 

[ASM5]

great for brain cancer

Doubtful many people use dihexa in the biohacker space regularly if cycling in and off and given your brain proper time to recover you should be fine. Plus I feel like we would have heard about some anecdotal cancer reports by now I’ve searched around and haven’t found any.

 

[User28823]

Doubtful many people use dihexa in the biohacker space regularly if cycling in and off and given your brain proper time to recover you should be fine. Plus I feel like we would have heard about some anecdotal cancer reports by now I’ve searched around and haven’t found any.

"a while"

buddy u have no idea what long term effects these biohacking drugs have on u until they're studied for 50+ years

 

[ASM5]

"a while"

buddy u have no idea what long term effects these biohacking drugs have on u until they're studied for 50+ years

The only way Dihexa would cause cancer is through the HGF/c met pathway, it’s up regulation has correlated with cancer, when you stop taking Dihexa the overactivation of this path way ceases returning back to base line, once it’s at base line risks are gone.

 

[ASM5]

A

The only way Dihexa would cause cancer is through the HGF/c met pathway, it’s up regulation has correlated with cancer, when you stop taking Dihexa the overactivation of this path way ceases returning back to base line, once it’s at base line risks are gone.

And since we know it’s safe short term(at least in rat studies), that means the only risk of cancer is when actually on cycle since HGF pathway would be active for 3 weeks, since we know it’s safe for short term use I don’t see much risk

 

[fika2]

M

Aderall is neurotoxic over time and I’ll be taking caffeine on occasion.

really only neurotoxic if ur taking a lot / enough to feel euphoric 24/7

not to mention you can use the dopamine to get better at doing what you'd like to do then hop off

 

[bottleofwater]

Ill only ever use neurtropixs when i do my gcses