Applied RU58841 for the first time today

[Deleted member 6963]

Noticed diffuse (?) thinning a while ago and decided to take action. Finasteride would be the last resort for me - not a fan of its effect on neurosteroids.

Ordered:
- RU58841 from a Chinese manufacturer (80g with 2 friends, 20g for me)
- Ethanol (non denatured, 96%)
- Propylene Glycol
- a small 0.01g scale
- set of 4 laboratory measuring cups (+pipettes)
- a funnel


I followed this guide to mix the RU58841: https://moreplatesmoredates.com/how-to-make-a-ru58841-solution/


Might update this thread in the future for other people interested in taking RU.
Feel free to comment in case you're interested in getting tagged for updates.

 

[randomvanish]

congrats. keep us updated.

 

[ifyouwannabemylover]

don't really understand using chinese rat piss over fin but you do you brah

 

[Kroker]

Interested in updates. How much did it cost you the 20mg RU only? and how much the rest?

I took Fin and I got sides so I'll look into RU. Include Dermaroller 1.5mm.

 

[Primordial]

RU58841 when absorbed goes systemic, so I hope you know the side effects for that. I don't get why ppl fear monger fin so much, chances of side effects are low and the side effects can be diminished if you take other actions jfl

 

[eduardkoopman]

RU58841 when absorbed goes systemic, so I hope you know the side effects for that. I don't get why ppl fear monger fin so much, chances of side effects are low and the side effects can be diminished if you take other actions jfl

what are the common side effects of RU58841??

 

[Mongrelcel]

Finasteride would be the last resort for me - not a fan of its effect on neurosteroids

elaborate?

 

[Primordial]

what are the common side effects of RU58841??

RU58841 is not FDA approved, not enough clinical trials so it's safety is not well known unlike finasteride which is FDA approved. So imagine saying fin is a last resort when RU58841 doesn't even have enough studies on it but it is known it goes systemic despite being applied topically. It is known that RU58841 affects your cardiovascular system, it causes chest pain and breathlessness, problems with vision, sexual problems. It blocks all androgens, even testosterone so if it's absorbed systemically then it could be really bad for men. Everything regarding it is based on anecdotes, they dropped the drug during the FDA approval process, it's unknown why so if ppl want to be their own test subjects and use it then go ahead. I would rather use a clinically proven treatment (finasteride) than this unknown drug which who knows could do what to you.

 

[eduardkoopman]

RU58841 is not FDA approved, not enough clinical trials so it's safety is not well known unlike finasteride which is FDA approved. So imagine saying fin is a last resort when RU58841 doesn't even have enough studies on it but it is known it goes systemic despite being applied topically. It is known that RU58841 affects your cardiovascular system, it causes chest pain and breathlessness, problems with vision, sexual problems. It blocks all androgens, even testosterone so if it's absorbed systemically then it could be really bad for men. Everything regarding it is based on anecdotes, they dropped the drug during the FDA approval process, it's unknown why so if ppl want to be their own test subjects and use it then go ahead. I would rather use a clinically proven treatment (finasteride) than this unknown drug which who knows could do what to you.

i Was thinking myself also. to add Ru58841 to my mix.
I am already on finastride and minoxidll, daily.

 

[CristianT]

@Linoob

 

[Primordial]

i Was thinking myself also. to add Ru58841 to my mix.
I am already on finastride and minoxidll, daily.

You don't need RU58841 if you're already on Finasteride.

 

[ChristianChad]

Keep us updated.

 

[eduardkoopman]

You don't need RU58841 if you're already on Finasteride.

I'm already on fina for like almost 2 years now. or maye 1.5 year. I added minox recently. like 2 months orso.
There was in the beginning some hair gains, on fina. But now it's stagant at best, but i think to feel like asif it's difuse thinning a bit now slowly over time. So, if that is true. i need to stop that process. because for me, hair = life. Without hair, I'm 100% sure game over with my skull shape, with my narrow-ish temples

 

[Primordial]

I'm already on fina for like almost 2 years now. or maye 1.5 year. I added minox recently. like 2 months orso.
There was in the beginning some hair gains, on fina. But now it's stagant at best, but i think to feel like asif it's difuse thinning a bit now slowly over time. So, if that is true. i need to stop that process. because for me, hair = life. Without hair, I'm 100% sure game over with my skull shape, with my narrow-ish temples

You might be getting shedding from the minoxidil since its only been 2 months. Finasteride should work for 10 years unless you have severe balding genes, in which case you can add dutasteride to your routine probably once or twice a week to prevent further baldness. It's most likely shedding from using minoxidil, which is normal.

 

[Deleted member 6963]

don't really understand using chinese rat piss over fin but you do you brah

Most big RU suppliers like Anageninc order from China and sell it for a profit. You're probably fine with tretinoin or Cialis from India. What's different about RU.
Also RU doesnt affect systemic hormone levels to the same degree Finasteride does.

Interested in updates. How much did it cost you the 20mg RU only? and how much the rest?

I took Fin and I got sides so I'll look into RU. Include Dermaroller 1.5mm.

20g. Don't remember tbh, I can look it up later again. But way cheaper than if I bought it from resellers.

RU58841 when absorbed goes systemic, so I hope you know the side effects for that. I don't get why ppl fear monger fin so much, chances of side effects are low and the side effects can be diminished if you take other actions jfl

Where do you have this from? RU might be go systemic to a very small degree. Fins mechanism of action is entirely systemic lol.
Also many people who experienced side effects on fin have no issues with RU.

what are the common side effects of RU58841??

None typically. In case side effects arise, they'd be what you'd expect from an androgen receptor antagonist.

RU58841 is not FDA approved, not enough clinical trials so it's safety is not well known unlike finasteride which is FDA approved. So imagine saying fin is a last resort when RU58841 doesn't even have enough studies on it but it is known it goes systemic despite being applied topically. It is known that RU58841 affects your cardiovascular system, it causes chest pain and breathlessness, problems with vision, sexual problems. It blocks all androgens, even testosterone so if it's absorbed systemically then it could be really bad for men. Everything regarding it is based on anecdotes, they dropped the drug during the FDA approval process, it's unknown why so if ppl want to be their own test subjects and use it then go ahead. I would rather use a clinically proven treatment (finasteride) than this unknown drug which who knows could do what to you.

I'm afraid you're ill informed.

You don't need RU58841 if you're already on Finasteride.

Can't generalize like this.



Funny video I found. The guy is pretty blackpilled jfl

 

[volcelfatcel]

Another cultured hairpilled man
@TRNA @SubhumanCurrycel

 

[Primordial]

@CookiesAndCream How am I ill-informed? RU58841 is not FDA approved, all we have are anecdotes and it's proven it does go systemic it's not a might. IT DOES. Finasteride has been studied for decades now so we know it's safety profile unlike RU58841. Use RU58841, I don't care, if you do get side effects let us know.

 

[Deleted member 6963]

@CookiesAndCream How am I ill-informed? RU58841 is not FDA approved, all we have are anecdotes and it's proven it does go systemic it's not a might. IT DOES. Finasteride has been studied for decades now so we know it's safety profile unlike RU58841. Use RU58841, I don't care, if you do get side effects let us know.

The FDA appoving or not is of major concern to me. It's a topical anti androgen. Not that complicated. No relevant side effects in the original trials.
Does a small percentage go systemic? Maybe, depends on many factors. Like I said, a small percentage.. with a very short half life.

I think most people eho used it will agree that the risk of side effects from it is lower than from Finasteride.

elaborate?

5 alpha reductase (which is inhibited by Finasteride/ dutasteride) does a lot more than just converting testosterone into dihydrotestosterone.
Mainly affects the GABAergic system in your brain.. might be a reason why some people have brain fog, feel depressed or have anxiety while on fin.

If you want to take Finasteride, it's up to you. I decided for myself that it won't be my first drug of choice.

 

[eduardkoopman]

unless you have severe balding genes,

i can't have servere blading genes. Because at age 37 when I started I was NW 2.5 at most.

 

[Primordial]

The FDA appoving or not is of major concern to me. It's a topical anti androgen. Not that complicated. No relevant side effects in the original trials.
Does a small percentage go systemic? Maybe, depends on many factors. Like I said, a small percentage.. with a very short half life.

I think most people eho used it will agree that the risk of side effects from it is lower than from Finasteride.



5 alpha reductase (which is inhibited by Finasteride/ dutasteride) does a lot more than just converting testosterone into dihydrotestosterone.
Mainly affects the GABAergic system in your brain.. might be a reason why some people have brain fog, feel depressed or have anxiety while on fin.

If you want to take Finasteride, it's up to you. I decided for myself that it won't be my first drug of choice.

Side effects seem to depend on the dosing, if you're doing 20mg I think you should be safe from the side effects.

 

[Primordial]

i can't have servere blading genes. Because at age 37 when I started I was NW 2.5 at most.

so it's shedding from minoxidil then?

 

[eduardkoopman]

so it's shedding from minoxidil then?

yeah could be. I didn't even know that Minox could cause shedding. I'll wait it out a few months, to see what happens.
I hope adding Ru won't be needed.

But I am willing to take risks, if needed. When it comes to my hair.

Because hair, life.

 

[Linoob]

RU58841 gave me chest pain, shortness of breath, palpatations. When I had an echo done, my left ventricular function was mildy reduced relative to one I had 12 months ago.

Be careful.

No more than 10g a day and scale up from there.

 

[KraftDurchLeid]

RU58841 gave me chest pain, shortness of breath, palpatations. When I had an echo done, my left ventricular function was mildy reduced relative to one I had 12 months ago.

Be careful.

No more than 10g a day and scale up from there.

u mean 10mg?

 

[Deleted member 7098]

Tag me in updates

 

[Linoob]

u mean 10mg?

Yes of course

 

[SOS-Sonic]

RU58841 is not FDA approved, not enough clinical trials so it's safety is not well known unlike finasteride which is FDA approved. So imagine saying fin is a last resort when RU58841 doesn't even have enough studies on it but it is known it goes systemic despite being applied topically. It is known that RU58841 affects your cardiovascular system, it causes chest pain and breathlessness, problems with vision, sexual problems. It blocks all androgens, even testosterone so if it's absorbed systemically then it could be really bad for men. Everything regarding it is based on anecdotes, they dropped the drug during the FDA approval process, it's unknown why so if ppl want to be their own test subjects and use it then go ahead. I would rather use a clinically proven treatment (finasteride) than this unknown drug which who knows could do what to you.

Well actually, iirc only 1 out of 17 subjects had detectable RU in their bloodstream. However, there has been no evidence that it affected their cardiovascular system or testosterone levels in any way because it was traces. And since you mentioned that there are no clinical trials, how can you say that it causes side effects? Isn't this double standards? There are no experiments to prove its safety, but there are non to prove that it is unsafe either.

In theory yes, RU will cause severe sides pretty quickly since it will block all androgens not just DHT. However, when we only apply 50mgs on our scalps, only a very small percent of it enter the bloodstream, and if your testosterone get inhibited by like 0.3% I doubt you will notice at all. The natural fluctuation of testosterone is probably way bigger than the amount that RU can suppress even if it does go systematic.

You are right in a sense that it is an experimental, and there is not enough data behind it, and I agree with you that fin is better for various reasons. However, don't believe baldcels on reddit that say their dicks fell off and their heart exploded because they touched RU.

And not to mention that the half is extremely short (less than a day), so if one experiences sides they can quit and they will be back to baseline the next day essentially.

 

[SOS-Sonic]

RU58841 gave me chest pain, shortness of breath, palpatations. When I had an echo done, my left ventricular function was mildy reduced relative to one I had 12 months ago.

Be careful.

No more than 10g a day and scale up from there.

Well 50mg is barely enough to maintain hair for the vast majority of people. And RU has the same binding affinity of testosterone, there is no way in hell 10mg will nuke your androgens to the point where you experienced all those symptoms. You literally gotta chemically castrate yourself with God knows what to reach that state. So I am guessing its all in your head due to the conditioning of the fear mongering baldcels.

 

[Lev Peshkov]

Noticed diffuse (?) thinning a while ago and decided to take action. Finasteride would be the last resort for me - not a fan of its effect on neurosteroids.

Ordered:
- RU58841 from a Chinese manufacturer (80g with 2 friends, 20g for me)
- Ethanol (non denatured, 96%)
- Propylene Glycol
- a small 0.01g scale
- set of 4 laboratory measuring cups (+pipettes)
- a funnel


I followed this guide to mix the RU58841: https://moreplatesmoredates.com/how-to-make-a-ru58841-solution/


Might update this thread in the future for other people interested in taking RU.
Feel free to comment in case you're interested in getting tagged for updates.

Will be using when I use tren even though I don’t bald on roids tren is dangerous and hair is just too important

 

[TitusA]

Noticed diffuse (?) thinning a while ago and decided to take action. Finasteride would be the last resort for me - not a fan of its effect on neurosteroids.

Ordered:
- RU58841 from a Chinese manufacturer (80g with 2 friends, 20g for me)
- Ethanol (non denatured, 96%)
- Propylene Glycol
- a small 0.01g scale
- set of 4 laboratory measuring cups (+pipettes)
- a funnel


I followed this guide to mix the RU58841: https://moreplatesmoredates.com/how-to-make-a-ru58841-solution/


Might update this thread in the future for other people interested in taking RU.
Feel free to comment in case you're interested in getting tagged for updates.

Shit made my hair shed so using it for harsh steroid cycles only. Getting regrowth (temples grown to the point im cutting back the dose because its reverted to my 14 year old hairlin) results from dutasteride alone 2 years in on 400mg test cruise.

 

[Primordial]

Well actually, iirc only 1 out of 17 subjects had detectable RU in their bloodstream. However, there has been no evidence that it affected their cardiovascular system or testosterone levels in any way because it was traces. And since you mentioned that there are no clinical trials, how can you say that it causes side effects? Isn't this double standards? There are no experiments to prove its safety, but there are non to prove that it is unsafe either.

In theory yes, RU will cause severe sides pretty quickly since it will block all androgens not just DHT. However, when we only apply 50mgs on our scalps, only a very small percent of it enter the bloodstream, and if your testosterone get inhibited by like 0.3% I doubt you will notice at all. The natural fluctuation of testosterone is probably way bigger than the amount that RU can suppress even if it does go systematic.

You are right in a sense that it is an experimental, and there is not enough data behind it, and I agree with you that fin is better for various reasons. However, don't believe baldcels on reddit that say their dicks fell off and their heart exploded because they touched RU.

And not to mention that the half is extremely short (less than a day), so if one experiences sides they can quit and they will be back to baseline the next day essentially.

spare me pls
yh only way to know without clinical trials is reddit posts tbh even though its not reliable

 

[Linoob]

Well 50mg is barely enough to maintain hair for the vast majority of people. And RU has the same binding affinity of testosterone, there is no way in hell 10mg will nuke your androgens to the point where you experienced all those symptoms. You literally gotta chemically castrate yourself with God knows what to reach that state. So I am guessing its all in your head due to the conditioning of the fear mongering baldcels.

I wasn't taking 10mg a day, I was taking 50mg a day - that's why I advise people to start low.

An echocardiogram I had done 2 weeks post-symptom / chest pain / SOB / episodes shows decreased heart / left ventricular function (EF%)

I also compared the results from an older echocardiogram (~12 months) which shows perfectly healthy heart function and significantly higher left ventricular function (EF%).

I have no incentive to lie and if it weren't for the test results mentioned above I'd likely still be taking RU58841.

Ultimately you can process that information however you please.

I'm not here to convince anyone, just stating my case study.

It doesn't make sense that this type of drug could cause such issues, but I choose to avoid RU58841 moving forward.

The reality is a small percentage of guys may just experience adverse cardiac-related side effects while others remain unscathed.

Stay safe man.

 

[Preoximerianas]

Ordered:
- RU58841 from a Chinese manufacturer (80g with 2 friends, 20g for me)

> Chinese manufacturer

Invite me to your funeral.

 

[hypergamy]

Most big RU suppliers like Anageninc order from China and sell it for a profit. You're probably fine with tretinoin or Cialis from India. What's different about RU.
Also RU doesnt affect systemic hormone levels to the same degree Finasteride does.


20g. Don't remember tbh, I can look it up later again. But way cheaper than if I bought it from resellers.


Where do you have this from? RU might be go systemic to a very small degree. Fins mechanism of action is entirely systemic lol.
Also many people who experienced side effects on fin have no issues with RU.


None typically. In case side effects arise, they'd be what you'd expect from an androgen receptor antagonist.


I'm afraid you're ill informed.



Can't generalize like this.



Funny video I found. The guy is pretty blackpilled jfl

JFL this fucking stupid.

“LoW dHt CaUsEs worse Bea r d growth”

fucking stupid. takes fin, dosent realize DHT=body hair. 99% of people mess with there hormones and aren’t educated at all.

 

[eduardkoopman]

congrats. keep us updated.

I'm starting today.
The RU345677855 is in.

I was and am on minox (5%) topical and fina (pill. 0.33 mg) already daily.
Now I added 5% RU to da mix.

Lets pray, for NW0 and full density hair

 

[maxmax901]

I'm starting today.
The RU345677855 is in.

I was and am on minox (5%) topical and fina (pill. 0.33 mg) already daily.
Now I added 5% RU to da mix.

Lets pray, for NW0 and full density hair

Yoooooo
Update ?

 

[eduardkoopman]

Yoooooo
Update ?

I'm still alive

 

[maxmax901]

I'm still alive

Nice
But how many heart attacks you had since ?

 

[eduardkoopman]

Nice
But how many heart attacks you had since ?